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Artikel ; Online: Assessment of cognitive functioning using the Mini Mental State Examination in men with Alcohol and Crack Cocaine Use Disorder.

Schuch, Jaqueline B / Becker, Natália / Rabelo-da-Ponte, Francisco Diego / Ornell, Felipe / Freitas, Hellen J M / Rebelatto, Fernando P / Sordi, Anne O / Pechansky, Flavio / von Diemen, Lisia / Kessler, Felix H P

Trends in psychiatry and psychotherapy

2023  Band 45, Seite(n) e20220567

Abstract: Introduction: Consumption of substances has been associated with cognitive impairment. The Mini Mental State Examination (MMSE) is an easy-to-apply screening tool used to assess cognitive functions.: Objectives: To evaluate the cognitive performance ... ...

Abstract Introduction: Consumption of substances has been associated with cognitive impairment. The Mini Mental State Examination (MMSE) is an easy-to-apply screening tool used to assess cognitive functions.
Objectives: To evaluate the cognitive performance of individuals with alcohol (AUD) and/or crack cocaine use disorder (CUD) and polysubstance use using the MMSE and to investigate the impact of substance use profile and the moderation effect of educational level on MMSE performance.
Methods: Cross-sectional study with 508 adult male inpatients diagnosed with substance use disorders (245 with AUD, 85 with CUD, and 178 with polysubstance use). Cognitive performance was assessed using the MMSE scale (total and composite scores).
Results: Individuals with AUD had worse total MMSE scores and scored worse for all three MMSE components compared to individuals with polysubstance use (p < 0.001, oral/written language comprehension, p < 0.001, attention/memory, and p = 0.007, motor functions). MMSE scores were positively correlated with educational level (p < 0.017), but were not associated with age, recent drug use, or years of drug use. Educational level moderated the impact of substance use on MMSE performance, especially total score and composite language comprehension score. Individuals with a low educational level (≤ 8 years) had worse performance than those with a high educational level (≥ 9 years), mainly in individuals with AUD (p < 0.001).
Discussion: Individuals with a low educational level and alcohol use are more prone to present cognitive impairment than crack cocaine users, especially involving language aspects. Better-preserved cognitive function could impact treatment adherence and might guide the decision of therapeutic strategies.
Mesh-Begriff(e) Adult ; Humans ; Male ; Crack Cocaine ; Cross-Sectional Studies ; Cognition ; Mental Status and Dementia Tests ; Substance-Related Disorders ; Ethanol
Chemische Substanzen Crack Cocaine ; Ethanol (3K9958V90M)
Sprache Englisch
Erscheinungsdatum 2023-03-08
Erscheinungsland Brazil
Dokumenttyp Journal Article
ZDB-ID 2708374-3
ISSN 2238-0019 ; 2238-0019
ISSN (online) 2238-0019
ISSN 2238-0019
DOI 10.47626/2237-6089-2022-0567
Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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