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  1. Book: Fundamentals of clinical trials

    Friedman, Lawrence M. / Furberg, Curt / DeMets, David L. / Reboussin, David M. / Granger, Christopher B.

    2015  

    Author's details Lawrence M. Friedman, Curt D. Furberg, David L. DeMets, David M. Reboussin, Christopher B. Granger
    Keywords Clinical Trials as Topic ; Research Design ; Klinische Prüfung
    Subject Arzneimittel ; Arzneimittelstudie
    Language English
    Size xxi, 550 Seiten, Diagramme
    Edition Fifth edition
    Publisher Springer
    Publishing place Cham
    Publishing country Switzerland
    Document type Book
    HBZ-ID HT019054042
    ISBN 978-3-319-307732 ; 9783319185392 ; 3-319-30773-8 ; 331918539X
    Database Catalogue ZB MED Medicine, Health

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  2. Book: Fundamentals of clinical trials

    Friedman, Lawrence M. / Furberg, Curt / DeMets, David L.

    2010  

    Author's details Lawrence M. Friedman ; Curt D. Furberg ; David L. DeMets
    Keywords Clinical Trials as Topic ; Research Design
    Language English
    Size XVIII, 445 S. : graph. Darst.
    Edition 4. ed.
    Publisher Springer
    Publishing place New York u.a.
    Publishing country United States
    Document type Book
    Note Literaturangaben
    HBZ-ID HT016556592
    ISBN 978-1-4419-1585-6 ; 9781441915863 ; 1-4419-1585-0 ; 1441915869
    Database Catalogue ZB MED Medicine, Health

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  3. Article ; Online: Approaches to data analyses of clinical trials.

    Furberg, Curt D / Friedman, Lawrence M

    Progress in cardiovascular diseases

    2012  Volume 54, Issue 4, Page(s) 330–334

    Abstract: There are two types of data analyses of randomized clinical trials (RCTs). The primary analyses are pre-specified in the protocol and the findings form the basis for recommendations and clinical decisions. They typically adhere to the intention-to-treat ... ...

    Abstract There are two types of data analyses of randomized clinical trials (RCTs). The primary analyses are pre-specified in the protocol and the findings form the basis for recommendations and clinical decisions. They typically adhere to the intention-to-treat principle. Secondary analyses are supplemental and of various sorts. Although some may be pre-specified, many are not. We encourage the use of the rich sources of data from large RCTs for these secondary purposes. Depending on the kinds of secondary analyses, whether they are pre-specified, and whether intention-to-treat analysis is used, the results range from being quite conclusive to being hypothesis generating. In this article we answer four questions related to secondary analysis with emphasis on sharing of data primarily from NIH-sponsored trials: Who has access to this information? What questions can be asked? What are the requirements? What are the common challenges?
    MeSH term(s) Access to Information ; Data Interpretation, Statistical ; Humans ; Randomized Controlled Trials as Topic/standards
    Language English
    Publishing date 2012-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 209312-1
    ISSN 1873-1740 ; 1532-8643 ; 0033-0620
    ISSN (online) 1873-1740 ; 1532-8643
    ISSN 0033-0620
    DOI 10.1016/j.pcad.2011.07.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Book: Fundamentals of clinical trials

    Friedman, Lawrence M. / Furberg, Curt / DeMets, David L.

    1996  

    Author's details Lawrence M. Friedman ; Curt D. Furberg ; David L. DeMets
    Keywords Clinical Trials ; Research Design ; Klinische Prüfung
    Subject Arzneimittel ; Arzneimittelstudie
    Language English
    Size XVIII, 361 S. : graph. Darst.
    Edition 3. ed.
    Publisher Mosby
    Publishing place St. Louis u.a.
    Publishing country Great Britain
    Document type Book
    Old title Bis 2. Aufl. u.d.T. Friedman, Lawrence M.: Fundamentals of clinical trials
    HBZ-ID HT006882019
    ISBN 0-8151-3356-1 ; 978-0-8151-3356-8
    Database Catalogue ZB MED Medicine, Health

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  5. Book: Fundamentals of clinical trials

    Friedman, Lawrence M / Furberg, Curt / DeMets, David L / Reboussin, David / Granger, Christopher B

    2015  

    Author's details Lawrence M. Friedman, Curt D. Furberg, David L. DeMets, David M. Reboussin, Christopher B. Granger
    MeSH term(s) Clinical Trials as Topic ; Research Design
    Language English
    Size xxi, 550 pages :, illustrations ;, 25 cm.
    Edition Fifth edition.
    Document type Book
    ISBN 9783319185385 ; 3319185381 ; 9783319185392 ; 331918539X
    Database Catalogue of the US National Library of Medicine (NLM)

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  6. Article: Von Mehren

    Friedman, Lawrence M / Macaulay, Stewart / Rehbinder, Manfred

    Von Mehren, Arthur T., [Geb. Ausg.]. - Tübingen : Mohr Siebeck [u.a.]

    2008  

    Document type Article
    Database Former special subject collection: coastal and deep sea fishing

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  7. Article: Von Mehren

    Friedman, Lawrence M / Macaulay, Stewart / Rehbinder, Manfred

    Von Mehren, Arthur T., [Geb. Ausg.]. - Tübingen : Mohr Siebeck [u.a.]

    2008  

    Document type Article
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  8. Book: Fundamentals of clinical trials

    Friedman, Lawrence M. / Furberg, Curt / DeMets, David L.

    1985  

    Author's details Lawrence M. Friedman ; Curt D. Furberg ; David L. DeMets
    Keywords Clinical Trials ; Research Design
    Language English
    Size XI, 302 S. : graph. Darst.
    Edition 2. ed., 1. print
    Publisher PSG Publ. Co
    Publishing place Littleton, Mass
    Publishing country United States
    Document type Book
    New title 3. Aufl. u.d.T. Fundamentals of clinical trials
    HBZ-ID HT003011273
    ISBN 0-88416-499-3 ; 978-0-88416-499-9
    Database Catalogue ZB MED Medicine, Health

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  9. Book: Data monitoring in clinical trials

    DeMets, David L / Furberg, Curt / Friedman, Lawrence M

    a case studies approach

    2006  

    Author's details David L. DeMets, Curt D. Furberg, Lawrence M. Friedman, editors
    MeSH term(s) Biomedical Research/standards ; Randomized Controlled Trials as Topic ; Clinical Trials Data Monitoring Committees
    Language English
    Size xxvi, 374 p. :, ill. ;, 24 cm.
    Publisher Springer
    Publishing place New York, NY
    Document type Book
    ISBN 9780387203300 ; 0387203303
    Database Catalogue of the US National Library of Medicine (NLM)

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  10. Book: Fundamentals of clinical trials

    Friedman, Lawrence M / Furberg, Curt / DeMets, David L

    2010  

    Author's details Lawrence M. Friedman, Curt D. Furberg, David L. DeMets
    MeSH term(s) Clinical Trials as Topic ; Research Design
    Language English
    Size xviii, 445 p. :, ill. ;, 24 cm.
    Edition 4th ed.
    Publisher Springer
    Publishing place New York
    Document type Book
    ISBN 9781441915856 ; 1441915850 ; 9781441915863 ; 1441915869
    Database Catalogue of the US National Library of Medicine (NLM)

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