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  1. Buch ; Dissertation / Habilitation: Aerosoltherapie der Pulmonalen Hypertonie

    Gessler, Tobias

    (Edition scientifique)

    2018  

    Verfasserangabe Tobias Gessler
    Serientitel Edition scientifique
    Schlagwörter Aerosoltherapie ; Allergene ; Allergie ; Allergieimpfung ; Anwendung ; Asthma ; Atem ; Atemnot ; Cortison ; Ernährung ; Habilitation ; Hausstaub ; Heuschnupfen ; Hyposensibilisierung ; Immunität ; Impfung ; Inhalation ; Inhalator ; Luft ; Lunge ; Milben ; Nanopartikel ; Nitrite ; Polen ; Respirationstrakt ; Schwellung ; Therapie ; Tierallergie ; bronchial
    Thema/Rubrik (Code) 610
    Sprache Deutsch ; Englisch
    Umfang 224 Seiten, Illustrationen, Diagramme, 21 cm
    Ausgabenhinweis 1. Auflage
    Verlag VVB Laufersweiler Verlag
    Erscheinungsort Giessen
    Erscheinungsland Deutschland
    Dokumenttyp Buch ; Dissertation / Habilitation
    Dissertation / Habilitation Habilitationsschrift, Justus-Liebig-Universität Gießen, 2016
    Anmerkung Enthält Sonderabdrucke in englischer Sprache
    HBZ-ID HT020366924
    ISBN 978-3-8359-6449-5 ; 3-8359-6449-6
    Datenquelle Katalog ZB MED Medizin, Gesundheit

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  2. Buch: Aerosoltherapie der Pulmonalen Hypertonie

    Gessler, Tobias

    (Edition Scientifique)

    2018  

    Abstract: Die Pulmonal Arterielle Hypertonie (PAH) ist eine seltene, aber schwerwiegende und lebensbedrohliche Erkrankung der distalen pulmonalen Arterien/Arteriolen, die durch einen Anstieg des Gefäßwiderstands und des Blutdrucks im Lungenkreislauf gekennzeichnet ...

    Serientitel Edition Scientifique
    Abstract Die Pulmonal Arterielle Hypertonie (PAH) ist eine seltene, aber schwerwiegende und lebensbedrohliche Erkrankung der distalen pulmonalen Arterien/Arteriolen, die durch einen Anstieg des Gefäßwiderstands und des Blutdrucks im Lungenkreislauf gekennzeichnet ist. Noch bis Ende des letzten Jahrhunderts waren bis auf das nebenwirkungsreiche intravenöse Prostazyklin keine spezifischen Medikamente verfügbar. Der pathophysiologische Hintergrund eines Ungleichgewichts zwischen Vasokonstriktion und Vas...
    Schlagwörter Ernährung ; Nitrite ; Habilitation ; Hyposensibilisierung ; Allergene ; Nanopartikel ; Polen ; Cortison ; Allergie ; Hausstaub ; Impfung ; Tierallergie ; Allergieimpfung ; Respirationstrakt ; Lunge ; Luft ; Heuschnupfen ; Schwellung ; Therapie ; Immunität ; Aerosoltherapie ; Asthma ; Milben ; Atem ; Inhalator ; Atemnot ; bronchial ; Anwendung ; Inhalation
    Sprache Deutsch
    Umfang 232 p.
    Verlag VVB Laufersweiler Verlag
    Dokumenttyp Buch
    Anmerkung Hochschulschriften Medizin
    Format 146 x 210
    ISBN 9783835964495 ; 3835964496
    Datenquelle PDA

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  3. Buch ; Dissertation / Habilitation: Einfluss der Ventilation und Perfusion auf die pulmonale Stickstoffmonoxid-Bildung im Modell der isolierten Kaninchenlunge

    Gessler, Tobias

    2013  

    Verfasserangabe vorgelegt von Tobias Gessler
    Schlagwörter Lungenkreislauf ; Stickstoffmonoxid ; Ventilation ; Perfusion ; Isoliert perfundiertes Organ ; Tiermodell
    Schlagwörter Perfusion ; Physiologische Beatmung ; Lungenventilation ; Lungenbelüftung ; Kleiner Kreislauf ; Pulmonalkreislauf
    Sprache Deutsch
    Umfang 111 S. : graph. Darst.
    Verlag VVB Laufersweiler Verlag
    Erscheinungsort Gießen, Lahn
    Erscheinungsland Deutschland
    Dokumenttyp Buch ; Dissertation / Habilitation
    Dissertation / Habilitation Gießen, Univ., Diss., 2013
    HBZ-ID HT017631401
    ISBN 978-3-8359-6000-8 ; 3-8359-6000-8
    Datenquelle Katalog ZB MED Medizin, Gesundheit

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  4. Artikel ; Online: lloprost delivered via the BREELIB

    Gessler, Tobias

    Therapeutic advances in respiratory disease

    2019  Band 13, Seite(n) 1753466619835497

    Abstract: Inhaled iloprost is a well-established medication to treat pulmonary arterial hypertension (PAH), a serious and potentially fatal disease of the pulmonary resistance vessels. The therapeutic administration of iloprost requires six to nine inhalations per ...

    Abstract Inhaled iloprost is a well-established medication to treat pulmonary arterial hypertension (PAH), a serious and potentially fatal disease of the pulmonary resistance vessels. The therapeutic administration of iloprost requires six to nine inhalations per day, due to the short biological half-life of this prostacyclin analogue. The I-Neb
    Mesh-Begriff(e) Administration, Inhalation ; Drug Administration Schedule ; Half-Life ; Humans ; Hypertension, Pulmonary/drug therapy ; Hypertension, Pulmonary/physiopathology ; Iloprost/administration & dosage ; Iloprost/adverse effects ; Iloprost/pharmacokinetics ; Nebulizers and Vaporizers ; Time Factors ; Vascular Resistance ; Vasodilator Agents/administration & dosage ; Vasodilator Agents/adverse effects ; Vasodilator Agents/pharmacokinetics
    Chemische Substanzen Vasodilator Agents ; Iloprost (JED5K35YGL)
    Sprache Englisch
    Erscheinungsdatum 2019-02-28
    Erscheinungsland England
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2476459-0
    ISSN 1753-4666 ; 1753-4658
    ISSN (online) 1753-4666
    ISSN 1753-4658
    DOI 10.1177/1753466619835497
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: Inhalation of repurposed drugs to treat pulmonary hypertension.

    Gessler, Tobias

    Advanced drug delivery reviews

    2018  Band 133, Seite(n) 34–44

    Abstract: Pulmonary arterial hypertension (PAH) is a rare, but severe and life-threatening disease characterized by vasoconstriction and remodeling of the pulmonary arterioles, leading to progressive increase in pulmonary vascular resistance and ultimately to ... ...

    Abstract Pulmonary arterial hypertension (PAH) is a rare, but severe and life-threatening disease characterized by vasoconstriction and remodeling of the pulmonary arterioles, leading to progressive increase in pulmonary vascular resistance and ultimately to right-heart failure. In the last two decades, significant progress in treatment of PAH has been made, with currently 12 drugs approved for targeted therapy. Among these, the stable prostacyclin analogues iloprost and treprostinil have been repurposed for inhalation. The paper highlights the development of the two drugs emphasizing the rationale and advantages of the inhalative approach. Despite substantial advances in the specific, mainly vasodilatory PAH therapy, disease progression is mostly inevitable and mortality remains unacceptably high. Thus, introduction of new drugs targeting the cancer-like remodeling of the diseased pulmonary arteries is urgently needed. Inhalation offers pulmonary selectivity and will hopefully pioneer the repurposing of novel highly potent drugs for effective aerosol therapy of PAH.
    Mesh-Begriff(e) Administration, Inhalation ; Antihypertensive Agents/administration & dosage ; Antihypertensive Agents/therapeutic use ; Drug Repositioning ; Epoprostenol/administration & dosage ; Epoprostenol/analogs & derivatives ; Epoprostenol/therapeutic use ; Humans ; Hypertension, Pulmonary/drug therapy ; Iloprost/administration & dosage ; Iloprost/therapeutic use
    Chemische Substanzen Antihypertensive Agents ; Epoprostenol (DCR9Z582X0) ; Iloprost (JED5K35YGL) ; treprostinil (RUM6K67ESG)
    Sprache Englisch
    Erscheinungsdatum 2018-06-08
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article ; Review
    ZDB-ID 639113-8
    ISSN 1872-8294 ; 0169-409X
    ISSN (online) 1872-8294
    ISSN 0169-409X
    DOI 10.1016/j.addr.2018.06.003
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel ; Online: Inhalative Pharmakotherapie in der Zukunft--Nanocarrier für die pulmonale Applikation von Arzneistoffen.

    Gessler, T

    Pneumologie (Stuttgart, Germany)

    2009  Band 63 Suppl 2, Seite(n) S113–6

    Abstract: Nanotechnological approaches promise considerable potential for the treatment of pneumological diseases, especially asthma and COPD (Chronic Obstructive Pulmonary Disease). At present numerous nanotechnological approaches are under examination, which ... ...

    Titelübersetzung Inhalative pharmacotherapy in the future--nanocarriers for pulmonary drug delivery.
    Abstract Nanotechnological approaches promise considerable potential for the treatment of pneumological diseases, especially asthma and COPD (Chronic Obstructive Pulmonary Disease). At present numerous nanotechnological approaches are under examination, which allow a controlled release of encapsulated drugs or diagnostics. These include nanocarriers composed of polymers or anorganic materials, liposomes, micelles, quantum dots, dendrimeres, polymer conjugates and other systems. Polymeric nanocarriers give the opportunity to control the temporal as well as the spatial distribution of drugs within the lung. By varying the composition, structure and dimension nanoparticles could offer a controlled and prolonged duration of effect of the encapsulated drugs as well as a regional and cell-specific drug targeting within the lung.
    Mesh-Begriff(e) Administration, Inhalation ; Asthma/drug therapy ; Drug Carriers/administration & dosage ; Drug Carriers/chemistry ; Forecasting ; Humans ; Nanomedicine/trends ; Nanostructures/administration & dosage ; Nanostructures/chemistry ; Nanostructures/ultrastructure ; Pulmonary Disease, Chronic Obstructive/drug therapy
    Chemische Substanzen Drug Carriers
    Sprache Deutsch
    Erscheinungsdatum 2009-12
    Erscheinungsland Germany
    Dokumenttyp English Abstract ; Journal Article ; Review
    ZDB-ID 607630-0
    ISSN 1438-8790 ; 0934-8387
    ISSN (online) 1438-8790
    ISSN 0934-8387
    DOI 10.1055/s-0029-1214768
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel ; Online: Conceptualizing, Measuring, and Mapping Contentiousness

    Gessler, Theresa / Hutter, Swen

    2021  

    Abstract: Portugal and Spain were among the countries hardest hit by the global financial crisis that led to the eurozone’s near collapse after the revelation of Greek public debt in late 2009. Both countries experienced a massive economic shock, as revealed by ... ...

    Abstract Portugal and Spain were among the countries hardest hit by the global financial crisis that led to the eurozone’s near collapse after the revelation of Greek public debt in late 2009. Both countries experienced a massive economic shock, as revealed by objective and subjective indicators (Chapter 3). Faced with a dire economic situation and increasing European pressure, the mainstream left in government – PS in Portugal and PSOE in Spain – announced severe austerity measures throughout 2009 and 2010 (Bremer and Vidal 2018). Consequently, the two countries saw union-organized protests against the measures early in the crisis (Accornero and Ramos Pinto 2015; Della Porta et al. 2017a; Kriesi et al. 2020; Portos 2019). Both countries experienced a turning point in 2011 when further noninstitutional actors entered the scene: Geração à Rasca [Screwed generation] in March 2011 in Portugal and 15M (named after the first large-scale protests on May 15, 2011) in Spain. According to some estimates, almost 5 percent of the Portuguese population took to the streets on March 12, 2011 (Carvalho 2018: 98). 15M and the battle cry of the central organizing network Democracia Real, Ya! [Real democracy now] led, after the first demonstration with about 20,000 participants on Puertas del Sol, to weeks of mass protests across the country.
    Schlagwörter ddc:320
    Thema/Rubrik (Code) 940
    Sprache Englisch
    Verlag Cambridge: Cambridge University Press
    Erscheinungsland de
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  8. Artikel ; Online: Social Media and Policy Responses to the COVID-19 Pandemic in Switzerland.

    Gilardi, Fabrizio / Gessler, Theresa / Kubli, Maël / Müller, Stefan

    Schweizerische Zeitschrift fur Politikwissenschaft = Revue suisse de science politique = Swiss political science review

    2021  Band 27, Heft 2, Seite(n) 243–256

    Abstract: We study the role of social media in debates regarding two policy responses to COVID-19 in Switzerland: face-mask rules and contact-tracing apps. We use a dictionary classifier to categorize 612'177 tweets by parties, politicians, and the public as well ... ...

    Abstract We study the role of social media in debates regarding two policy responses to COVID-19 in Switzerland: face-mask rules and contact-tracing apps. We use a dictionary classifier to categorize 612'177 tweets by parties, politicians, and the public as well as 441'458 articles published in 76 newspapers between February and August 2020. We distinguish between "problem" (COVID-19) and "solutions" (face masks and contact-tracing apps) and, using a vector autoregression approach, we analyze the relationship between their salience on social and traditional media, as well as among different groups on social media. We find that overall attention to COVID-19 was not driven by endogenous dynamics between the different actors. By contrast, the debate on face masks was led by the attentive public and by politicians, whereas parties and newspapers followed. The results illustrate how social media challenge the capacity of party and media elites to craft a consensus regarding the appropriateness of different measures as responses to a major crisis.
    Sprache Englisch
    Erscheinungsdatum 2021-05-25
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2085219-8
    ISSN 1662-6370 ; 1424-7755 ; 1420-3529
    ISSN (online) 1662-6370
    ISSN 1424-7755 ; 1420-3529
    DOI 10.1111/spsr.12458
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel: No Country for Asylum Seekers? How Short-Term Exposure to Refugees Influences Attitudes and Voting Behavior in Hungary.

    Gessler, Theresa / Tóth, Gergő / Wachs, Johannes

    Political behavior

    2021  Band 44, Heft 4, Seite(n) 1813–1841

    Abstract: How does exposure to refugees influence political behavior? We present evidence from Hungary, a country with widespread anti-immigration attitudes, that short term exposure during the 2015 refugee crisis predicts anti-refugee voting and sentiment. We ... ...

    Abstract How does exposure to refugees influence political behavior? We present evidence from Hungary, a country with widespread anti-immigration attitudes, that short term exposure during the 2015 refugee crisis predicts anti-refugee voting and sentiment. We code exposure to refugees at the settlement level using reports from state media, an independent online news site, and an online social media aggregator. Settlements through which refugees traveled showed significantly higher anti-refugee voting in a national referendum in 2016. The effect decreases sharply with distance. Using a difference-in-differences model, we find that the far-right opposition gained, while the governing right-wing party lost votes in these settlements in subsequent parliamentary elections. This suggests incumbents are punished by voters skeptical of immigration regardless of their policy position. Survey data supports this finding of a competition among right-wing parties, as individuals in exposed settlements are more fearful of immigrants and support restrictive policies only if they identify as right-wing.
    Sprache Englisch
    Erscheinungsdatum 2021-02-09
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 2018635-6
    ISSN 1573-6687 ; 0190-9320
    ISSN (online) 1573-6687
    ISSN 0190-9320
    DOI 10.1007/s11109-021-09682-1
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  10. Buch ; Online ; Dissertation / Habilitation: Development of FPGA-based algorithms for the data acquisition of the Belle II pixel detector

    Geßler, Thomas

    2015  

    Titelvarianten Entwicklung von FPGA-basierten Algorithmen für die Datenaufnahme des Belle II Pixeldetektors
    Verfasserangabe Thomas Geßler
    Sprache Englisch
    Umfang Online-Ressource
    Verlag Universitätsbibliothek
    Erscheinungsort Gießen
    Dokumenttyp Buch ; Online ; Dissertation / Habilitation
    Dissertation / Habilitation Gießen, Justus-Liebig-Universität, Diss., 2015
    Datenquelle Katalog der Technische Informationsbibliothek Hannover

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