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Artikel ; Online: VANESSA-Shiny Apps for Accelerated Time-series Analysis and Visualization of

Ghosh, Arijit / Sheeba, Vasu

2022 Band 37, Heft 2, Seite(n) 222–231

Abstract: Chronobiologists and sleep researchers often need to estimate various rhythm and sleep parameters from locomotor activity data from different organisms. The available open-source or expensive paid tools do not offer consolidated analysis and ... ...

Abstract	Chronobiologists and sleep researchers often need to estimate various rhythm and sleep parameters from locomotor activity data from different organisms. The available open-source or expensive paid tools do not offer consolidated analysis and visualization options in one bundle, are often cumbersome for users unfamiliar with coding, offer very low customization options, introduce sources of human errors by requiring users to manually pick period and power values from periodogram plots, and do not generate reproducible reports. We present VANESSA, a family of cross-platform apps written in R, which, in our opinion, have several advantages compared with available tools-(a) open-source; (b) automatic period-power detection; (c) time-series filtering and smoothing; (d) high-resolution publication-quality figures with dynamic coloring, resizing, and light/dark shading; (e) reproducible code-report generation; (f) analysis and visualization of multiple monitor files, defining genotypes and replicates separately; and (g) sleep profile analysis, various sleep parameter estimations, quantification, bout analysis, and latency analysis. The current version of the app is for data acquired through
Mesh-Begriff(e)	Animals ; Circadian Rhythm ; Drosophila ; Sleep
Sprache	Englisch
Erscheinungsdatum	2022-02-25
Erscheinungsland	United States
Dokumenttyp	Letter ; Research Support, Non-U.S. Gov't
ZDB-ID	896387-3
ISSN	1552-4531 ; 0748-7304
ISSN (online)	1552-4531
ISSN	0748-7304
DOI	10.1177/07487304221077662
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel: Amelioration of sodium and arsenic toxicity in Salvinia natans L. with 2,4-D priming through physiological responses

Saha, Indraneel / Ghosh, Arijit / Adak, Malay Kumar

Environmental science and pollution research. 2022 Feb., v. 29, no. 6

2022

Abstract: Sodium (Na) and arsenic (As) toxicity were monitored by hyperaccumulation of metals in Salvinia natans L. with 2,4-dichlorophenoxyacetic acid (2,4-D) induction. Salvinia was recorded with significant bioaccumulation of those metals with de-folding of ... ...

Abstract	Sodium (Na) and arsenic (As) toxicity were monitored by hyperaccumulation of metals in Salvinia natans L. with 2,4-dichlorophenoxyacetic acid (2,4-D) induction. Salvinia was recorded with significant bioaccumulation of those metals with de-folding of cellular attributes in sustenance under toxic environment. 2,4-D priming has revised the growth components like net assimilation rate and relative water content to register initial plants’ survival against Na and As. Proline biosynthesis supported in the maintenance of osmotic adjustment and plants sustained better activity through subdued electrolytic leakage. Oxidative stress due to both Na and As exposure is responsible for induction under significant moderation of lipid peroxidation and protein carbonization by 2,4-D application was evident to release the stress from metal and metalloids. Reactive oxygen species (ROS) like superoxide and hydrogen peroxide accumulation were monitored with activity of NADP(H)-oxidase. However, it was downregulated by 2,4-D to check the oxidative damages. Superoxide dismutase and peroxidases were significantly moderated to reduce the oxidative degradation for both metals with 2,4-D induction. Glutathione metabolism and recycling of ascorbate with monodehydroascorbate activity were other features to maintain the redox homeostasis for metal toxicity. At the molecular level, polymorphic variations of concern genes in redox cascades demarked significantly for those two metals and established the biomarker for those metals, respectively. As a whole, the biocompatibility of auxin herbicide in Salvinia may raise the possibility for auxin metabolism and thereby, the bioaccumulation to Na and As vis-à-vis tolerance for ecological safety is established.
Schlagwörter	2,4-D ; Salvinia natans ; arsenic ; auxins ; bioaccumulation ; biocompatibility ; biomarkers ; biosynthesis ; carbonization ; glutathione ; homeostasis ; hydrogen peroxide ; hyperaccumulators ; lipid peroxidation ; net assimilation rate ; oxidative stress ; peroxidases ; pollution ; research ; sodium ; superoxide dismutase ; toxicity ; water content
Sprache	Englisch
Erscheinungsverlauf	2022-02
Umfang	p. 9232-9247.
Erscheinungsort	Springer Berlin Heidelberg
Dokumenttyp	Artikel
ZDB-ID	1178791-0
ISSN	1614-7499 ; 0944-1344
ISSN (online)	1614-7499
ISSN	0944-1344
DOI	10.1007/s11356-021-16246-7
Datenquelle	NAL Katalog (AGRICOLA)

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Artikel ; Online: Deciphering the Origin of Regioselectivity in Ru(II)-Catalyzed C-H Annulation of

Rajput, Janavi / Ghosh, Arijit / Pawar, Amit B / Mondal, Bhaskar

The Journal of organic chemistry

2024 Band 89, Heft 10, Seite(n) 6838–6846

Abstract: Understanding the reaction mechanism and origin of regioselectivity in transition metal-catalyzed C-H activation/annulation reactions with 1,3-diynes has remained an intriguing challenge. In this article, to establish the mechanism and decipher the ... ...

Abstract	Understanding the reaction mechanism and origin of regioselectivity in transition metal-catalyzed C-H activation/annulation reactions with 1,3-diynes has remained an intriguing challenge. In this article, to establish the mechanism and decipher the origin of regioselectivity, we report a detailed computational density functional theory-based mechanistic investigation on the recently developed Ru(II)-catalyzed [4 + 2] annulation of
Sprache	Englisch
Erscheinungsdatum	2024-05-03
Erscheinungsland	United States
Dokumenttyp	Journal Article
ZDB-ID	123490-0
ISSN	1520-6904 ; 0022-3263
ISSN (online)	1520-6904
ISSN	0022-3263
DOI	10.1021/acs.joc.4c00209
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Buch ; Online: Sparse Geometric Set Systems and the Beck-Fiala Conjecture

Dutta, Kunal / Ghosh, Arijit

2023

Abstract: We investigate the combinatorial discrepancy of geometric set systems having bounded shallow cell complexity in the \emph{Beck-Fiala} setting, where each point belongs to at most $t$ ranges. For set systems with shallow cell complexity $\psi(m,k)=g(m)k^{ ... ...

Abstract	We investigate the combinatorial discrepancy of geometric set systems having bounded shallow cell complexity in the \emph{Beck-Fiala} setting, where each point belongs to at most $t$ ranges. For set systems with shallow cell complexity $\psi(m,k)=g(m)k^{c}$, where $(i)$ $g(m) = o(m^{\varepsilon})$ for any $\varepsilon\in (0,1],$ $(ii)$ $\psi$ is non-decreasing in $m$, and $(iii)$ $c>0$ is independent of $m$ and $k$, we get a discrepancy bound of \[ O\left(\sqrt{\left(\log n+\left(t^{c}g(n)\right)^{\frac{1}{1+c}}\right)\log n}\right).\] For $t=\omega(\log^2 n)$, in several cases, such as for set systems of points and half-planes / disks / pseudo-disks in $\mathbb{R}^2$, points and orthants in $\mathbb{R}^3$ etc., these bounds are $o(\sqrt{t})$, which verifies (and improves upon) the conjectured bound of Beck and Fiala~\emph{(Disc. Appl. Math., 1981)}. Our bounds are obtained by showing the existence of \emph{matchings with low crossing number}, using the multiplicative weights update method of Welzl \emph{(SoCG, 1988)}, together with the recent bound of Mustafa \emph{(Disc. Comp. Geom., 2015)} on \emph{shallow packings} of set systems in terms of their shallow cell complexity. For set systems of shallow cell complexity $\psi(m,k)=m^{c_1}g(m)k^{c}$, we obtain matchings with crossing number at most \[ O\left(\left(n^{c_1}g(n)t^{c}\right)^{\frac{1}{1+c_1+c}}\right).\] These are of independent interest.
Schlagwörter	Computer Science - Computational Geometry
Thema/Rubrik (Code)	511
Erscheinungsdatum	2023-01-09
Erscheinungsland	us
Dokumenttyp	Buch ; Online
Datenquelle	BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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Artikel ; Online: Socio-economic impact of COVID-19 pandemic: evidence from India and Bangladesh

Deb, Santus Kumar / Sarkar, Anirban / Ghosh, Arijit

Journal of Foodservice Business Research. 2023 Mar. 04, v. 26, no. 2 p.402-423

2023

Abstract: COVID-19 has destabilized economies, lives all over the globe with devastating impacts. Physical and mental health suffered hugely due to this pandemic. Moreover, educational institutes were forced to shift from offline to online mode. This study aims to ...

Abstract	COVID-19 has destabilized economies, lives all over the globe with devastating impacts. Physical and mental health suffered hugely due to this pandemic. Moreover, educational institutes were forced to shift from offline to online mode. This study aims to identify critical societal constructs which got impacted due to the COVID-19 pandemic in India and Bangladesh. Further, a comparative analysis has been carried out to assess these impacts between these two countries from a social science point of view. A cross-sectional study has been conducted through a structured questionnaire based on pilot study. Google Survey form link of questionnaire was active from March 15, 2020 to July 14, 2020 in which 1023 responses were received with a response rate of 54%. After the elimination of missing responses, 802 complete responses were finally coded on 48 variables including demographic profile of the respondents. Factor analysis is used to identify critical constructs of the study whereas hypothesis testing to carry out for comparative understanding. The study found that COVID-19 pandemic has severely impact on psychological, educational, economic, and social aspects of both countries whereas Bangladesh has significant adverse impact than India. Economic stimulus program such as tax exemption, EMI moratoriums, mental health training, E-learning, low interest rate of soft loan disbursement are noteworthy requirement to overcome the adverse impact of COVID-19.
Schlagwörter	COVID-19 infection ; cross-sectional studies ; electronic learning ; factor analysis ; food service ; loans ; mental health ; pandemic ; questionnaires ; research ; social sciences ; socioeconomic factors ; surveys ; Bangladesh ; India ; Anxiety ; COVID-19 ; social science ; stress
Sprache	Englisch
Erscheinungsverlauf	2023-0304
Umfang	p. 402-423.
Erscheinungsort	Routledge
Dokumenttyp	Artikel ; Online
ZDB-ID	2094789-6
ISSN	1537-8039 ; 1537-8020
ISSN (online)	1537-8039
ISSN	1537-8020
DOI	10.1080/15378020.2022.2063619
Datenquelle	NAL Katalog (AGRICOLA)

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Artikel ; Online: Ru(II)-Catalyzed Regioselective Redox-Neutral [4 + 2] Annulation of

Ghosh, Arijit / Sapkal, Goraksha T / Pawar, Amit B

The Journal of organic chemistry

2023 Band 88, Heft 7, Seite(n) 4704–4719

Abstract: Herein, we report Ru(II)-catalyzed C-H/N-H bond functionalization ... ...

Abstract	Herein, we report Ru(II)-catalyzed C-H/N-H bond functionalization of
Sprache	Englisch
Erscheinungsdatum	2023-03-09
Erscheinungsland	United States
Dokumenttyp	Journal Article
ZDB-ID	123490-0
ISSN	1520-6904 ; 0022-3263
ISSN (online)	1520-6904
ISSN	0022-3263
DOI	10.1021/acs.joc.3c00175
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: High-grade serous ovarian carcinoma, the "Achiles' hill" for clinicians and molecular biologists: a molecular insight.

Bhattacharya, Rittwika / Ghosh, Arijit / Mukhopadhyay, Soma

Molecular biology reports

2023 Band 50, Heft 11, Seite(n) 9511–9519

Abstract: High-grade serous ovarian carcinoma (HGSOC), the deadliest ovarian cancer, alone accounts for 90% of all its subtypes. Characterized by hallmark mutation of TP53, HGSOC show diverse molecular etiology. HGSOC can arise from both ovarian epithelium as well ...

Abstract	High-grade serous ovarian carcinoma (HGSOC), the deadliest ovarian cancer, alone accounts for 90% of all its subtypes. Characterized by hallmark mutation of TP53, HGSOC show diverse molecular etiology. HGSOC can arise from both ovarian epithelium as well as the fimbrial epithelium of the fallopian tube. Ovulation induced reactive oxygen species, follicular fluid associated growth factor induced stemness, deregulation of hormone receptors like ER, FSHR, AR and hormones like FSH, LH, prolonged ovulation cycle, use of oral contraceptives are agonists of HGSOC while parity, breastfeeding provide protective effect from HGSOC development. Apart from a generic TP53 mutation, mutation of BRCA1/2, RAD51, BRIP1, PALB2, CHEK2, RAD50 etc., were reportedly associated with development of HGSOC. Epigenetic events like methylation of RASSF1A of RAS signaling pathway,OR51L1, OR51I1, OR51F1 etc. has been reported in HGSOC. Micro-RNAs like miR-1290, miR 27-a-3p miR23a, miR205 were reportedly upregulated in HGSOC. Amongst its cognate subtypes viz. differentiated, immunoreactive, mesenchymal, and proliferative, mesenchymal, and proliferative show worst prognosis. A system biology approach showed five major altered pathways in HGSOC, namely, RB, PI3K/RAS, NOTCH, HRR and FOXM1 signaling. For chemonaive patients, drugs that helps in efflux of reduced glutathione or prevent the redox coupling of GSH-GSSG, like Cisplatin, could be considered as the best therapeutic choice for HGSOC. For patients with BRCA1/2 mutations, PARP inhibitors alone or with Bevacizumab can be effective. Immune checkpoint inhibitors could be effective against immunoreactive subtypes. Identification of genes deregulated in chemoresistance could provide better insights in dealing with the disease.
Mesh-Begriff(e)	Pregnancy ; Female ; Humans ; BRCA1 Protein ; BRCA2 Protein ; Ovarian Neoplasms/pathology ; MicroRNAs/genetics ; MicroRNAs/therapeutic use
Chemische Substanzen	BRCA1 protein, human ; BRCA1 Protein ; BRCA2 protein, human ; BRCA2 Protein ; MicroRNAs
Sprache	Englisch
Erscheinungsdatum	2023-09-22
Erscheinungsland	Netherlands
Dokumenttyp	Journal Article ; Review
ZDB-ID	186544-4
ISSN	1573-4978 ; 0301-4851
ISSN (online)	1573-4978
ISSN	0301-4851
DOI	10.1007/s11033-023-08760-3
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Buch ; Online ; Dissertation / Habilitation: Empirical analyses in applied microeconomics against spatial settings

Ghosh, Arijit [Verfasser] / Bauer, Thomas K. [Gutachter] / Ahlfeldt, Gabriel [Gutachter]

2024

Verfasserangabe	Arijit Ghosh ; Gutachter: Thomas K. Bauer, Gabriel Ahlfeldt ; Fakultät für Wirtschaftswissenschaften
Schlagwörter	Wirtschaft ; Economics
Thema/Rubrik (Code)	sg330
Sprache	Englisch
Verlag	Ruhr-Universität Bochum
Erscheinungsort	Bochum
Dokumenttyp	Buch ; Online ; Dissertation / Habilitation
Datenquelle	Digitale Dissertationen im Internet

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Buch ; Artikel ; Online: Replication

Garnache, Cloé / Ghosh, Arijit / Gibney, Garreth

Can Technology Solve the Principal-Agent Problem? Evidence from China's War on Air Pollution

2024

Abstract: Greenstone et al. examine the effect of the introduction of automatic air pollution monitoring on the reporting of local air pollution in China. Using 654 regression discontinuity designs (RDDs) based on city-level variation in the day that monitoring ... ...

Abstract	Greenstone et al. examine the effect of the introduction of automatic air pollution monitoring on the reporting of local air pollution in China. Using 654 regression discontinuity designs (RDDs) based on city-level variation in the day that monitoring was automated, they find an immediate and lasting increase of 35 percent in reported PM10 concentrations post-automation. Moreover, they find that automation's introduction increases online searches for face masks and air filters by 200 percent and 28 percent, respectively, using an RDD. Results are consistent when using an event study design. First, we were able to computationally replicate the results. Second, we find that results are robust to more flexible specifications of the weather variables, to re-constructed weather variables using the same matching procedure as the authors (i.e., closest station) and meteorological data with additional weather stations, to alternative construction of the weather variables using an inverse distance weighted approach of the surrounding weather stations, and to more flexible choices of fixed effects (up to the city level). Finally, we find limited evidence of discontinuity in objective measures of ground pollution (i.e., AOD) for a sub-sample using alternative weather variables. The estimate, however, is economically insignificant. Moreover, no discontinuity is observed in the full sample. Therefore, we believe this result does not invalidate the original study's findings.
Schlagwörter	ddc:330 ; D82 ; O13 ; P28 ; Q53 ; Q55 ; Q58
Thema/Rubrik (Code)	333
Sprache	Englisch
Verlag	s.l.: Institute for Replication (I4R)
Erscheinungsland	de
Dokumenttyp	Buch ; Artikel ; Online
Datenquelle	BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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Artikel ; Online: Highly selective fluorescent turn-on-off sensing of OH

Bhowal, Soumya / Ghosh, Arijit

RSC advances

2021 Band 11, Heft 45, Seite(n) 27787–27800

Abstract: Herein we report a multifunctional high performance metal organic framework (Zn-DHNDC MOF) based chemosensor that displays an exceptional excited state intramolecular proton transfer (ESIPT) tuned fluorescence turn-on-off response for ... ...

Abstract	Herein we report a multifunctional high performance metal organic framework (Zn-DHNDC MOF) based chemosensor that displays an exceptional excited state intramolecular proton transfer (ESIPT) tuned fluorescence turn-on-off response for OH
Sprache	Englisch
Erscheinungsdatum	2021-08-16
Erscheinungsland	England
Dokumenttyp	Journal Article
ISSN	2046-2069
ISSN (online)	2046-2069
DOI	10.1039/d1ra03078g
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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