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  1. Buch: The new executive brain

    Goldberg, Elkhonon

    frontal lobes in a complex world

    2009  

    Verfasserangabe Elkhonon Goldberg
    Schlagwörter Frontal Lobe / physiology ; Brain Diseases / physiopathology ; Mental Processes / physiology ; Frontal lobes ; Neuropsychology ; Frontal lobes--Physiology ; Brain--Diseases--Pathophysiology
    Thema/Rubrik (Code) 612.825
    Sprache Englisch
    Umfang XV, 334 S. : Ill., 24 cm
    Verlag Oxford Univ. Press
    Erscheinungsort Oxford u.a.
    Erscheinungsland Vereinigtes Königreich
    Dokumenttyp Buch
    Anmerkung Includes bibliographical references and index
    HBZ-ID HT016161287
    ISBN 978-0-19-532940-7 ; 0-19-532940-6
    Datenquelle Katalog ZB MED Medizin, Gesundheit

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  2. Buch: Die Regie im Gehirn

    Goldberg, Elkhonon

    wo wir Pläne schmieden und Entscheidungen treffen

    2002  

    Titelübersetzung The executive brain
    Verfasserangabe Elkhonon Goldberg. Vorw. von Oliver Sacks. [Übers.: Andrea Viala]
    Schlagwörter Frontal Lobe / physiopathology ; Brain Damage, Chronic / physiopathology ; Mental Processes / physiology ; Stirnhirn ; Hirnfunktion
    Schlagwörter Gehirn ; Hirnleistung ; Hirnaktivität ; Hirnphysiologie ; Gehirnphysiologie ; Gehirnaktivität ; Gehirnfunktion ; Frontalhirn ; Lobus frontalis cerebri ; Stirnlappen ; Frontallappen ; Scheitellappen
    Sprache Deutsch
    Umfang 340 S. : Ill., 22 cm
    Verlag VAK-Verl.-GmbH
    Erscheinungsort Kirchzarten bei Freiburg
    Erscheinungsland Deutschland
    Dokumenttyp Buch
    Anmerkung Aus dem Engl. übers.
    HBZ-ID HT013315057
    ISBN 3-935767-04-8 ; 978-3-935767-04-0
    Datenquelle Katalog ZB MED Medizin, Gesundheit

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  3. Artikel ; Online: Commentary on "Consciousness in a multilevel architecture: Evidence from the right side of the brain" by B.M. Velichkovsky et al.

    Goldberg, Elkhonon

    Consciousness and cognition

    2019  Band 73, Seite(n) 102753

    Mesh-Begriff(e) Brain ; Consciousness ; Humans
    Sprache Englisch
    Erscheinungsdatum 2019-05-30
    Erscheinungsland United States
    Dokumenttyp Letter ; Comment
    ZDB-ID 1106647-7
    ISSN 1090-2376 ; 1053-8100
    ISSN (online) 1090-2376
    ISSN 1053-8100
    DOI 10.1016/j.concog.2019.05.001
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel ; Online: Large-scale distributed networks and cerebral hemispheres.

    Goldberg, Elkhonon / Tulviste, Jaan

    Cortex; a journal devoted to the study of the nervous system and behavior

    2022  Band 152, Seite(n) 53–58

    Abstract: The two main large-scale distributed networks, Central Executive (CEN) and Default Mode (DMN) have been extensively studied, but their relationship to hemispheric specialization has not been comprehensively addressed. We present evidence that they are ... ...

    Abstract The two main large-scale distributed networks, Central Executive (CEN) and Default Mode (DMN) have been extensively studied, but their relationship to hemispheric specialization has not been comprehensively addressed. We present evidence that they are neuroanatomically asymmetric: the CEN components are volumetrically larger in the right hemisphere, and DMN components are volumetrically larger in the left hemisphere. Based on this, the possibility that CEN and DMN are also functionally asymmetric is introduced and implications of the putative functional asymmetry of large-scale distributed networks for refining our understanding of hemispheric specialization are examined.
    Mesh-Begriff(e) Brain ; Cerebrum ; Humans ; Magnetic Resonance Imaging ; Nerve Net
    Sprache Englisch
    Erscheinungsdatum 2022-04-05
    Erscheinungsland Italy
    Dokumenttyp Journal Article
    ZDB-ID 280622-8
    ISSN 1973-8102 ; 0010-9452
    ISSN (online) 1973-8102
    ISSN 0010-9452
    DOI 10.1016/j.cortex.2022.03.010
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Buch: Creativity

    Goldberg, Elkhonon

    the human brain in the age of innovation

    2018  

    Verfasserangabe by Elkhonon Goldberg
    Mesh-Begriff(e) Brain/physiology ; Creativity
    Sprache Englisch
    Umfang p. ;, cm.
    Dokumenttyp Buch
    ISBN 9780190466497 ; 0190466499
    Datenquelle Katalog der US National Library of Medicine (NLM)

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  6. Buch ; Online: Deep learning in a bilateral brain with hemispheric specialization

    Rajagopalan, Chandramouli / Rawlinson, David / Goldberg, Elkhonon / Kowadlo, Gideon

    2022  

    Abstract: The brains of all bilaterally symmetric animals on Earth are divided into left and right hemispheres. The anatomy and functionality of the hemispheres have a large degree of overlap, but there are asymmetries and they specialize to possess different ... ...

    Abstract The brains of all bilaterally symmetric animals on Earth are divided into left and right hemispheres. The anatomy and functionality of the hemispheres have a large degree of overlap, but there are asymmetries and they specialize to possess different attributes. Several studies have used computational models to mimic hemispheric asymmetries with a focus on reproducing human data on semantic and visual processing tasks. In this study, we aimed to understand how dual hemispheres could interact in a given task. We propose a bilateral artificial neural network that imitates a lateralization observed in nature: that the left hemisphere specializes in specificity and the right in generalities. We used two ResNet-9 convolutional neural networks with different training objectives and tested it on an image classification task. Our analysis found that the hemispheres represent complementary features that are exploited by a network head which implements a type of weighted attention. The bilateral architecture outperformed a range of baselines of similar representational capacity that don't exploit differential specialization. The results demonstrate the efficacy of bilateralism, contribute to an understanding of bilateralism in biological brains and the architecture serves as an inductive bias when designing new AI systems.

    Comment: 14 pages, 11 figures
    Schlagwörter Quantitative Biology - Neurons and Cognition ; Computer Science - Artificial Intelligence ; Computer Science - Machine Learning ; Computer Science - Neural and Evolutionary Computing ; I.2.6 ; I.5.0 ; I.5.1
    Thema/Rubrik (Code) 501 ; 006
    Erscheinungsdatum 2022-09-08
    Erscheinungsland us
    Dokumenttyp Buch ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  7. Artikel ; Online: Multiple Neuroinvasive Pathways in COVID-19.

    Bougakov, Dmitri / Podell, Kenneth / Goldberg, Elkhonon

    Molecular neurobiology

    2020  Band 58, Heft 2, Seite(n) 564–575

    Abstract: COVID-19 is a highly infectious viral disease caused by the novel coronavirus SARS-CoV-2. While it was initially regarded as a strictly respiratory illness, the impact of COVID-19 on multiple organs is increasingly recognized. The brain is among the ... ...

    Abstract COVID-19 is a highly infectious viral disease caused by the novel coronavirus SARS-CoV-2. While it was initially regarded as a strictly respiratory illness, the impact of COVID-19 on multiple organs is increasingly recognized. The brain is among the targets of COVID-19, and it can be impacted in multiple ways, both directly and indirectly. Direct brain infection by SARS-CoV-2 may occur via axonal transport via the olfactory nerve, eventually infecting the olfactory cortex and other structures in the temporal lobe, and potentially the brain stem. A hematogenous route, which involves viral crossing of blood-brain barrier, is also possible. Secondary mechanisms involve hypoxia due to respiratory failure, as well as aberrant immune response leading to various forms of encephalopathy, white matter damage, and abnormal blood clotting resulting in stroke. Multiple neurological symptoms of COVID-19 have been described. These involve anosmia/ageusia, headaches, seizures, mental confusion and delirium, and coma. There is a growing concern that in a number of patients, long-term or perhaps even permanent cognitive impairment will persist well after the recovery from acute illness. Furthermore, COVID-19 survivors may be at increased risk for developing neurodegenerative diseases years or decades later. Since COVID-19 is a new disease, it will take months or even years to characterize the exact nature, scope, and temporal extent of its long-term neurocognitive sequelae. To that end, rigorous and systematic longitudinal follow-up will be required. For this effort to succeed, appropriate protocols and patient registries should be developed and put in place without delay now.
    Mesh-Begriff(e) Anosmia/virology ; Blood-Brain Barrier/virology ; Brain/virology ; COVID-19/complications ; Coma/virology ; Delirium/virology ; Headache/virology ; Humans ; Seizures/virology
    Schlagwörter covid19
    Sprache Englisch
    Erscheinungsdatum 2020-09-29
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Review
    ZDB-ID 645020-9
    ISSN 1559-1182 ; 0893-7648
    ISSN (online) 1559-1182
    ISSN 0893-7648
    DOI 10.1007/s12035-020-02152-5
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel ; Online: The brain after COVID-19: Compensatory neurogenesis or persistent neuroinflammation?

    Goldberg, Elkhonon / Podell, Kenneth / Sodickson, Daniel K / Fieremans, Els

    EClinicalMedicine

    2020  Band 31, Seite(n) 100684

    Sprache Englisch
    Erscheinungsdatum 2020-12-24
    Erscheinungsland England
    Dokumenttyp Journal Article
    ISSN 2589-5370
    ISSN (online) 2589-5370
    DOI 10.1016/j.eclinm.2020.100684
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel: Multiple Neuroinvasive Pathways in COVID-19

    Bougakov, Dmitri / Podell, Kenneth / Goldberg, Elkhonon

    Mol. Neurobiol

    Abstract: COVID-19 is a highly infectious viral disease caused by the novel coronavirus SARS-CoV-2. While it was initially regarded as a strictly respiratory illness, the impact of COVID-19 on multiple organs is increasingly recognized. The brain is among the ... ...

    Abstract COVID-19 is a highly infectious viral disease caused by the novel coronavirus SARS-CoV-2. While it was initially regarded as a strictly respiratory illness, the impact of COVID-19 on multiple organs is increasingly recognized. The brain is among the targets of COVID-19, and it can be impacted in multiple ways, both directly and indirectly. Direct brain infection by SARS-CoV-2 may occur via axonal transport via the olfactory nerve, eventually infecting the olfactory cortex and other structures in the temporal lobe, and potentially the brain stem. A hematogenous route, which involves viral crossing of blood-brain barrier, is also possible. Secondary mechanisms involve hypoxia due to respiratory failure, as well as aberrant immune response leading to various forms of encephalopathy, white matter damage, and abnormal blood clotting resulting in stroke. Multiple neurological symptoms of COVID-19 have been described. These involve anosmia/ageusia, headaches, seizures, mental confusion and delirium, and coma. There is a growing concern that in a number of patients, long-term or perhaps even permanent cognitive impairment will persist well after the recovery from acute illness. Furthermore, COVID-19 survivors may be at increased risk for developing neurodegenerative diseases years or decades later. Since COVID-19 is a new disease, it will take months or even years to characterize the exact nature, scope, and temporal extent of its long-term neurocognitive sequelae. To that end, rigorous and systematic longitudinal follow-up will be required. For this effort to succeed, appropriate protocols and patient registries should be developed and put in place without delay now.
    Schlagwörter covid19
    Verlag WHO
    Dokumenttyp Artikel
    Anmerkung WHO #Covidence: #808452
    Datenquelle COVID19

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  10. Artikel ; Online: Multiple Neuroinvasive Pathways in COVID-19

    Bougakov, Dmitri / Podell, Kenneth / Goldberg, Elkhonon

    Molecular Neurobiology ; ISSN 0893-7648 1559-1182

    2020  

    Schlagwörter Cellular and Molecular Neuroscience ; covid19
    Sprache Englisch
    Verlag Springer Science and Business Media LLC
    Erscheinungsland us
    Dokumenttyp Artikel ; Online
    DOI 10.1007/s12035-020-02152-5
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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