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  1. Artikel ; Online: [Titelangabe fehlt]

    Gräfe, Daniel

    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin

    2023  Band 195, Heft 10, Seite(n) 873

    Titelübersetzung Kommentar zu „KINDER – MRT-Befunde nach COVID-19-Infektion bei Kindern“.
    Sprache Deutsch
    Erscheinungsdatum 2023-10-04
    Erscheinungsland Germany
    Dokumenttyp Journal Article
    ZDB-ID 554830-5
    ISSN 1438-9010 ; 0340-1618 ; 0936-6652 ; 1433-5972 ; 1438-9029
    ISSN (online) 1438-9010
    ISSN 0340-1618 ; 0936-6652 ; 1433-5972 ; 1438-9029
    DOI 10.1055/a-2101-9301
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Buch ; Dissertation / Habilitation: Strahlentherapie des Analkarzinoms

    Gräfe, Daniel / Kocher, Martin / Goeser, Tobias

    2020  

    Körperschaft Universitätsklinikum Köln / Klinik und Poliklinik für Radioonkologie, Cyberknife- und Strahlentherapie
    Verfasserangabe vorgelegt von Daniel Gräfe ; 1. Gutachter: Professor Dr. med. M. Kocher, 2. Gutachter: Universitätsprofessor Dr. med. T. Goeser ; aus der Klinik und Poliklinik für Radioonkologie, Cyberknife udn Strahlentherapie der Universität zu Köln
    Thema/Rubrik (Code) 610
    Sprache Deutsch
    Umfang 72 Seiten, Diagramme
    Erscheinungsort Köln
    Erscheinungsland Deutschland
    Dokumenttyp Buch ; Dissertation / Habilitation
    Dissertation / Habilitation Dissertation, Universität zu Köln, 2020
    HBZ-ID HT020563760
    Datenquelle Katalog ZB MED Medizin, Gesundheit

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  3. Artikel: Kommentar zu „KINDER – MRT-Befunde nach COVID-19-Infektion bei Kindern“

    Gräfe, Daniel

    RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren

    2023  Band 195, Heft 10, Seite(n) 873–873

    Sprache Deutsch
    Erscheinungsdatum 2023-10-01
    Verlag Georg Thieme Verlag KG
    Erscheinungsort Stuttgart ; New York
    Dokumenttyp Artikel
    ZDB-ID 554830-5
    ISSN 1438-9010 ; 1438-9029 ; 0340-1618 ; 0936-6652 ; 1433-5972
    ISSN (online) 1438-9010
    ISSN 1438-9029 ; 0340-1618 ; 0936-6652 ; 1433-5972
    DOI 10.1055/a-2101-9301
    Datenquelle Thieme Verlag

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  4. Buch ; Dissertation / Habilitation: Vergleichende Genexpressionsanalyse zwischen dem nukleären Antigen La und der überlappenden putativen Methyltransferase HSPC133 in einem neuen transgenen Autoimmunmodell

    Gräfe, Daniel

    2008  

    Verfasserangabe vorgelegt von Daniel Gräfe
    Sprache Deutsch
    Umfang 160 Bl., Ill., graph. Darst.
    Erscheinungsland Deutschland
    Dokumenttyp Buch ; Dissertation / Habilitation
    Dissertation / Habilitation Dresden, Techn. Univ., Diss., 2008
    HBZ-ID HT015875569
    Datenquelle Katalog ZB MED Medizin, Gesundheit

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  5. Artikel ; Online: Kongenitale Lungenfehlbildungen : Diagnostik und Therapie.

    Dohna, M / Hirsch, W F / Dingemann, J / Gräfe, D

    Radiologie (Heidelberg, Germany)

    2024  Band 64, Heft 5, Seite(n) 357–365

    Abstract: Performance: Congenital pulmonary malformations (CPM) are rare and can be associated with high morbidity. Clinical presentation, diagnostic procedures, imaging, and therapy of CPM are discussed.: Achievements: Today, most CPM can be diagnosed ... ...

    Titelübersetzung Congenital pulmonary malformations : Diagnosis and treatment.
    Abstract Performance: Congenital pulmonary malformations (CPM) are rare and can be associated with high morbidity. Clinical presentation, diagnostic procedures, imaging, and therapy of CPM are discussed.
    Achievements: Today, most CPM can be diagnosed prenatally by ultrasound. Postnatally, respiratory symptoms up to respiratory failure and recurrent lower respiratory tract infection are typical findings. Due to low diagnostic accuracy of chest x‑ray in CPM, all children with prenatal diagnosis of CPM or postnatally suspected CPM should undergo cross-sectional imaging.
    Practical recommendations: Based on imaging alone, the various subtypes of CPM cannot be definitively differentiated, which is why histological confirmation remains the gold standard. Surgical resection is the standard of care with minimally invasive procedures increasingly being employed. In certain situations, a watch-and-wait approach is possible.
    Mesh-Begriff(e) Humans ; Lung/abnormalities ; Lung/diagnostic imaging ; Lung/surgery ; Infant, Newborn ; Respiratory System Abnormalities/diagnosis ; Respiratory System Abnormalities/therapy ; Respiratory System Abnormalities/surgery ; Female ; Male ; Tomography, X-Ray Computed ; Lung Diseases/diagnosis ; Lung Diseases/therapy ; Lung Diseases/congenital ; Lung Diseases/diagnostic imaging ; Ultrasonography, Prenatal
    Sprache Deutsch
    Erscheinungsdatum 2024-03-28
    Erscheinungsland Germany
    Dokumenttyp English Abstract ; Journal Article ; Review
    ISSN 2731-7056
    ISSN (online) 2731-7056
    DOI 10.1007/s00117-024-01291-3
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel: Large Numbers for Small Children-Up to What Age Do Infants Benefit from a Longer Echo Time in Cerebral T2 MRI Sequences?

    Beeskow, Anne Bettina / Hirsch, Franz Wolfgang / Denecke, Timm / Sorge, Ina / Gräfe, Daniel

    Children (Basel, Switzerland)

    2024  Band 11, Heft 5

    Abstract: In newborns, white matter shows a high T2-weighted (T2w) signal in MRI with poor grey-white matter contrast. To increase this contrast, an extremely long echo time (TE) is used in the examination of children. It is not known up to what age this long TE ... ...

    Abstract In newborns, white matter shows a high T2-weighted (T2w) signal in MRI with poor grey-white matter contrast. To increase this contrast, an extremely long echo time (TE) is used in the examination of children. It is not known up to what age this long TE should be used. The purpose of this study was to find up to what age a long TE should be used in infants. In the prospective study, 101 infants (0-18 months) underwent cranial MRI at 3 Tesla. T2-weighted Fast Spin Echo sequences with long TE (200 ms) and medium TE (100 ms) were used. The signal intensities of the cortex and white matter were measured and the grey-white matter contrast (MC) was calculated. A cut-off age was determined. The T2w sequences with long TE had a statistically significantly higher MC until the age of six months (medium TE: 0.1 ± 0.05, Long TE: 0.19 ± 0.07;
    Sprache Englisch
    Erscheinungsdatum 2024-04-24
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2732685-8
    ISSN 2227-9067
    ISSN 2227-9067
    DOI 10.3390/children11050511
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel ; Konferenzbeitrag: Auswirkung von Übergewicht im Kindes- und Jugendalter auf den Kniegelenksknorpel: Erste vorläufige Ergebnisse einer prospektiven monozentrischen T2-Mapping-Studie

    Roth, C / Sorge, I / Gräfe, D / Witt, M / Böker, E / Hirsch, F W

    RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren

    2023  Band 195, Heft S 02

    Veranstaltung/Kongress 60. GPR Jahrestagung, Wien, 2023-09-14
    Sprache Deutsch
    Erscheinungsdatum 2023-09-01
    Verlag Georg Thieme Verlag
    Erscheinungsort Stuttgart ; New York
    Dokumenttyp Artikel ; Konferenzbeitrag
    ZDB-ID 554830-5
    ISSN 1438-9010 ; 1438-9029 ; 0340-1618 ; 0936-6652 ; 1433-5972
    ISSN (online) 1438-9010
    ISSN 1438-9029 ; 0340-1618 ; 0936-6652 ; 1433-5972
    DOI 10.1055/s-0043-1771424
    Datenquelle Thieme Verlag

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  8. Artikel ; Online: Chest magnetic resonance imaging in cystic fibrosis: technique and clinical benefits.

    Gräfe, Daniel / Prenzel, Freerk / Hirsch, Franz Wolfgang

    Pediatric radiology

    2022  Band 53, Heft 4, Seite(n) 640–648

    Abstract: Cystic fibrosis (CF) is one of the most common inherited and life-shortening pulmonary diseases in the Caucasian population. With the widespread introduction of newborn screening and the development of modulator therapy, tremendous advances have been ... ...

    Abstract Cystic fibrosis (CF) is one of the most common inherited and life-shortening pulmonary diseases in the Caucasian population. With the widespread introduction of newborn screening and the development of modulator therapy, tremendous advances have been made in recent years both in diagnosis and therapy. Since paediatric CF patients tend to be younger and have lower morbidity, the type of imaging modality that should be used to monitor the disease is often debated. Computed tomography (CT) is sensitive to many pulmonary pathologies, but radiation exposure limits its use, especially in children and adolescents. Conventional pulmonary magnetic resonance imaging (MRI) is a valid alternative to CT and, in most cases, provides sufficient information to guide treatment. Given the expected widespread availability of sequences with ultra-short echo times, there will be even fewer reasons to perform CT for follow-up of patients with CF. This review aims to provide an overview of the process and results of monitoring CF with MRI, particularly for centres not specialising in the disease.
    Mesh-Begriff(e) Adolescent ; Infant, Newborn ; Humans ; Child ; Cystic Fibrosis/diagnostic imaging ; Cystic Fibrosis/pathology ; Lung/pathology ; Magnetic Resonance Imaging/methods ; Tomography, X-Ray Computed/methods ; Neonatal Screening
    Sprache Englisch
    Erscheinungsdatum 2022-11-14
    Erscheinungsland Germany
    Dokumenttyp Review ; Journal Article
    ZDB-ID 124459-0
    ISSN 1432-1998 ; 0301-0449
    ISSN (online) 1432-1998
    ISSN 0301-0449
    DOI 10.1007/s00247-022-05539-9
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel ; Online: Managing an open nasofrontal encephalocele after birth.

    Apostolou, Nicolas / Gräfe, Daniel / Knüpfer, Matthias / Krause, Matthias

    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery

    2022  Band 39, Heft 2, Seite(n) 535–540

    Abstract: Encephaloceles are relatively uncommon in western countries. Most of the reported cases involve occipital encephaloceles. Open frontal encephaloceles comprise a rare entity. Most of them will be detected during early prenatal diagnostic, whereas the ... ...

    Abstract Encephaloceles are relatively uncommon in western countries. Most of the reported cases involve occipital encephaloceles. Open frontal encephaloceles comprise a rare entity. Most of them will be detected during early prenatal diagnostic, whereas the majority of the pregnancies will be terminated after the consent of the parents. Open frontal encephaloceles pose a great challenge to neurosurgeons as well as anesthesiologists, as these infants present with a microcephaly, non-physiological intracranial anatomy, and low birth weight, thus making the infant prone to excessive blood loss, hypothermia, and death. Neonates born with an incomplete cutaneous coverage are exposed to an imminent threat to life due to the risk of meningitis, necessitating surgical repair in the first days of life. We represent a rare case of an open nasofrontal encephalocele managed surgically in the first day of life. Surgery did not influence the neurological outcome of the patient.
    Mesh-Begriff(e) Infant ; Infant, Newborn ; Humans ; Encephalocele/surgery ; Neurosurgeons ; Microcephaly
    Sprache Englisch
    Erscheinungsdatum 2022-11-10
    Erscheinungsland Germany
    Dokumenttyp Case Reports ; Journal Article
    ZDB-ID 605988-0
    ISSN 1433-0350 ; 0302-2803 ; 0256-7040
    ISSN (online) 1433-0350
    ISSN 0302-2803 ; 0256-7040
    DOI 10.1007/s00381-022-05620-6
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  10. Artikel ; Online: Increased Musculoskeletal Deformities And Decreased Lung Volume In Patients After Ea/Tef Repair - A Real-Time Mri Study.

    Aubert, Ophelia / Lacher, Martin / Mayer, Steffi / Frahm, Jens / Voit, Dirk / Rosolowski, Maciej / Widenmann, Anke / Hirsch, Franz Wolfgang / Gräfe, Daniel

    Annals of surgery

    2024  

    Abstract: Objective: This study aims to assess morphological and functional postoperative changes after open or minimally invasive (MIS) repair of esophageal atresia (EA) compared to healthy controls by thoracic real-time MRI.: Summary background data: ... ...

    Abstract Objective: This study aims to assess morphological and functional postoperative changes after open or minimally invasive (MIS) repair of esophageal atresia (EA) compared to healthy controls by thoracic real-time MRI.
    Summary background data: Musculoskeletal deformities and pulmonary morbidity are common in children after EA repair. The real-time MRI is a novel technique that provides ultrafast, high-quality images during spontaneous breathing, without sedation even in young children.
    Methods: Children aged 3-18 years were prospectively examined with a 3 Tesla MRI. Musculoskeletal deformities, static thoracic cross-sectional areas (CSA) at three different levels and lung volumes, as well as dynamic right-to-left ratio of CSA of hemithoraces and lung volumes during forced breathing were evaluated.
    Results: 72 children (42 open, 8 MIS, 22 controls) were recruited. In the EA group, rib fusions and adhesions (78%, P<0.01) and scoliosis (15%, P=0.32) were found after thoracotomy, but not after MIS. Mean right-to-left ratio of CSA and lung volumes were lower after EA repair compared to controls (P <0.05), indicating impaired thoracic and lung development. The number of thoracotomies was a significant risk factor for smaller thoracic volumes (P<0.05).
    Conclusions: For the first time, morphological changes and thoracic motility after EA repair were visualized by dynamic real-time MRI. Children after EA repair show decreased right-sided thoracic and lung development compared to controls. Open repair leads to significantly more musculoskeletal deformities. This study emphasizes that musculoskeletal morbidity following a thoracotomy in infancy is high.
    Sprache Englisch
    Erscheinungsdatum 2024-02-08
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 340-2
    ISSN 1528-1140 ; 0003-4932
    ISSN (online) 1528-1140
    ISSN 0003-4932
    DOI 10.1097/SLA.0000000000006193
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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