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  1. Buch: Connective tissue disorders

    Gordon, Caroline / Gross, Wolfgang L.

    (An atlas of investigation and management)

    2011  

    Verfasserangabe Caroline Gordon ; Wolfgang L. Gross
    Serientitel An atlas of investigation and management
    Sprache Englisch
    Umfang X, 122 S. : zahlr. Ill.
    Verlag Clinical Publ
    Erscheinungsort Oxford u.a.
    Erscheinungsland Vereinigte Staaten
    Dokumenttyp Buch
    HBZ-ID HT016686806
    ISBN 978-1-84692-074-5 ; 1-84692-074-4 ; 9781846926341 ; 1846926343
    Datenquelle Katalog ZB MED Medizin, Gesundheit

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  2. Buch ; Konferenzbeitrag: ANCA associated vasculitides

    Gross, Wolfgang L.

    immunological and clinical aspects ; [proceedings of the Fourth International Workshop on ANCA (Antineutrophil Cytoplasmic Antibodies) and the Second International Colloquium on Wegener's Granulomatosis and Vasculitic Disorders, held May 28 - 30, 1992, in Lübeck, Germany]

    (Advances in experimental medicine and biology ; 336)

    1993  

    Titelvarianten ANCA-associated
    Veranstaltung/Kongress International Colloquium on Wegener's Granulomatosis and Vasculitic Disorders (2, 1992, Lübeck) ; International Workshop on ANCA (4, 1992, Lübeck)
    Verfasserangabe ed. by Wolfgang L. Gross
    Serientitel Advances in experimental medicine and biology ; 336
    Überordnung
    Schlagwörter Vasculitis / congresses ; Autoantibodies / congresses ; Wegener's Granulomatosis / congresses ; Vaskulitis ; Granulomatose mit Polyangiitis
    Schlagwörter Morbus Wegener ; Wegenersche Granulomatose ; Granulomatosis Wegener ; Wegener Granulomatose ; Wegener Granulomatose Syndrom ; Wegener-Klinger Granulomatose ; Klinger-Wegener-Granulomatose ; GPA ; Granuloma gangraenescens ; Gefäßentzündung ; Vasculitis ; Vascularitis ; Vaskulitiden ; Angiitis ; Systemische Vasculitis ; Vasculitides ; Angiitides
    Sprache Englisch
    Umfang XIX, 552 S. : Ill., graph. Darst.
    Verlag Plenum Press
    Erscheinungsort New York u.a.
    Erscheinungsland Vereinigte Staaten
    Dokumenttyp Buch ; Konferenzbeitrag
    HBZ-ID HT006133742
    ISBN 0-306-44573-5 ; 978-0-306-44573-6
    Datenquelle Katalog ZB MED Medizin, Gesundheit

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  3. Buch: Therapie der Immunvaskulitiden

    Gross, Wolfgang L.

    (UNI-MED science)

    2000  

    Verfasserangabe [Wolfgang L. Gross]
    Serientitel UNI-MED science
    Schlagwörter Vaskulitis ; Immunkrankheit ; Therapie
    Schlagwörter Medizinische Behandlung ; Behandlung ; Krankenbehandlung ; Immunopathie ; Immunologische Krankheit ; Immunologische Erkrankung ; Gefäßentzündung ; Vasculitis ; Vascularitis ; Vaskulitiden ; Angiitis ; Systemische Vasculitis ; Vasculitides ; Angiitides
    Sprache Deutsch
    Umfang 136 S. : Ill., graph. Darst.
    Ausgabenhinweis 1. Aufl.
    Verlag UNI-MED-Verl
    Erscheinungsort Bremen u.a.
    Erscheinungsland Deutschland
    Dokumenttyp Buch
    HBZ-ID HT013017071
    ISBN 3-89599-512-6 ; 978-3-89599-512-5
    Datenquelle Katalog ZB MED Medizin, Gesundheit

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  4. Buch: Systemic lupus erythematosus

    Gordon, Caroline / Gross, Wolfgang L

    (Visual guide for clinicians)

    2012  

    Verfasserangabe [edited by] Caroline Gordon, Wolfgang L. Gross
    Serientitel Visual guide for clinicians
    Mesh-Begriff(e) Lupus Erythematosus, Systemic/diagnosis ; Lupus Erythematosus, Systemic/therapy ; Sjogren's Syndrome/diagnosis ; Sjogren's Syndrome/therapy
    Sprache Englisch
    Umfang viii, 56 p. :, ill., ;, 31 cm.
    Verlag Clinical Pub
    Erscheinungsort Oxford
    Dokumenttyp Buch
    Anmerkung Content first published in 2011 as part of Connective tissue diseases : an atlas of investigation and management (Oxford : Clinical Publishing).
    ISBN 9781846921001 ; 1846921007 ; 9781846926433 ; 1846926432
    Datenquelle Katalog der US National Library of Medicine (NLM)

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  5. Buch: Connective tissue diseases

    Gordon, Caroline / Gross, Wolfgang L

    an atlas of investigation and management

    2011  

    Verfasserangabe [editors], Caroline Gordon, Wolfgang L. Gross
    Mesh-Begriff(e) Connective Tissue Diseases ; Autoimmune Diseases
    Sprache Englisch
    Umfang x, 122 p. :, ill.
    Verlag Clinical Pub
    Erscheinungsort Oxford
    Dokumenttyp Buch
    ISBN 9781846920745 ; 9781846926341 ; 1846920744 ; 1846926343
    Datenquelle Katalog der US National Library of Medicine (NLM)

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  6. Artikel ; Online: Current understanding of the pathogenesis of granulomatosis with polyangiitis (Wegener's).

    Csernok, Elena / Gross, Wolfgang L

    Expert review of clinical immunology

    2013  Band 9, Heft 7, Seite(n) 641–648

    Abstract: Granulomatosis with polyangiitis (Wegener's) (GPA) is a multisystem disease of unknown etiology, characterized by granulomata of the respiratory tract and systemic necrotizing vasculitis. Antineutrophil cytoplasmic antibodies (ANCA) with specificity for ... ...

    Abstract Granulomatosis with polyangiitis (Wegener's) (GPA) is a multisystem disease of unknown etiology, characterized by granulomata of the respiratory tract and systemic necrotizing vasculitis. Antineutrophil cytoplasmic antibodies (ANCA) with specificity for proteinase 3 (PR3) are a defining feature of this disease. GPA usually starts as a granulomatous disease of the respiratory tract and, in the majority of patients, progresses to systemic disease with PR3-ANCA-associated vasculitis. Today, epidemiological evidence indicates that GPA develops as a result of complex gene-environment interactions. The nature of these risk factors and pathogenic mechanisms involved, however, are only just beginning to be understood. Clinical data and in vitro experimental results point to the pathogenic pathways involved in tissue lesion development, in which ANCA, cellular immunity, neutrophils extracellular traps, fibroblasts, vascular endothelial cells and inflammatory mediators play a major role. Today, the pathophysiological significance of PR3-ANCA is still unclear and the pathogenic pathways leading to granuloma formation are not explained. New data unexpectedly suggest that the destruction of nasal cartilage in GPA is mainly mediated by fibroblasts that can be blocked by corticosteroids.
    Mesh-Begriff(e) Adrenal Cortex Hormones/therapeutic use ; Antibodies, Antineutrophil Cytoplasmic/metabolism ; Autoantigens/immunology ; Endothelium, Vascular/immunology ; Gene-Environment Interaction ; Granuloma/immunology ; Granulomatosis with Polyangiitis/drug therapy ; Granulomatosis with Polyangiitis/immunology ; Humans ; Immunity, Cellular ; Microscopic Polyangiitis/drug therapy ; Microscopic Polyangiitis/immunology ; Myeloblastin/immunology ; Nasal Cartilages/drug effects ; Nasal Cartilages/pathology ; Respiratory System/pathology
    Chemische Substanzen Adrenal Cortex Hormones ; Antibodies, Antineutrophil Cytoplasmic ; Autoantigens ; Myeloblastin (EC 3.4.21.76)
    Sprache Englisch
    Erscheinungsdatum 2013-07
    Erscheinungsland England
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2274260-8
    ISSN 1744-8409 ; 1744-666X
    ISSN (online) 1744-8409
    ISSN 1744-666X
    DOI 10.1586/1744666X.2013.811052
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel ; Online: Treatment of ANCA-associated vasculitides (AAV).

    Holle, Julia U / Gross, Wolfgang L

    Autoimmunity reviews

    2013  Band 12, Heft 4, Seite(n) 483–486

    Abstract: Treatment of AAV follows the principle of a combined remission induction and maintenance strategy and is adapted in a stage and activity-adapted fashion. So far the combination therapy of glucocorticoids and conventional immunosuppressive drugs has ... ...

    Abstract Treatment of AAV follows the principle of a combined remission induction and maintenance strategy and is adapted in a stage and activity-adapted fashion. So far the combination therapy of glucocorticoids and conventional immunosuppressive drugs has mainly been used to control disease. This approach has led to a significant improvement in outcome in spite of persistently high early mortality rates of nearly 11% within the first year. Besides conventional treatment, biologics have emerged as a new treatment option. The paper summarizes the current evidence for the use of conventional therapy and biologics in AAV.
    Mesh-Begriff(e) Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis/drug therapy ; Churg-Strauss Syndrome/drug therapy ; Granulomatosis with Polyangiitis/drug therapy ; Humans ; Immunosuppressive Agents/therapeutic use ; Microscopic Polyangiitis/drug therapy ; Recurrence ; Remission Induction
    Chemische Substanzen Immunosuppressive Agents
    Sprache Englisch
    Erscheinungsdatum 2013-02
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2144145-5
    ISSN 1873-0183 ; 1568-9972
    ISSN (online) 1873-0183
    ISSN 1568-9972
    DOI 10.1016/j.autrev.2012.08.007
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel: Zeitschrift für Rheumatologie in neuer Gestalt. Was kommt--was bleibt?

    Gross, Wolfgang L

    Zeitschrift fur Rheumatologie

    2006  Band 65, Heft 1, Seite(n) 5

    Titelübersetzung Publications for rheumatology in new forms. What will come--what will remain?.
    Mesh-Begriff(e) Germany ; Information Dissemination/methods ; Information Storage and Retrieval/methods ; Information Storage and Retrieval/trends ; Internet ; Online Systems ; Periodicals as Topic/trends ; Publishing/trends ; Rheumatology/trends
    Sprache Deutsch
    Erscheinungsdatum 2006-06-19
    Erscheinungsland Germany
    Dokumenttyp Editorial
    ZDB-ID 124985-x
    ISSN 1435-1250 ; 0340-1855 ; 0301-6382
    ISSN (online) 1435-1250
    ISSN 0340-1855 ; 0301-6382
    DOI 10.1007/s00393-006-0043-6
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel ; Online: Vasculitis in 2011: the renaissance of granulomatous inflammation in AAV.

    Gadola, Stephan D / Gross, Wolfgang L

    Nature reviews. Rheumatology

    2012  Band 8, Heft 2, Seite(n) 74–76

    Abstract: In 2011, the year that subtypes of ANCA-associated vasculitis (AAV) were officially renamed according to key pathological characteristics, important progress was made not only in differentiating these subtypes, but also in understanding—and treating— ... ...

    Abstract In 2011, the year that subtypes of ANCA-associated vasculitis (AAV) were officially renamed according to key pathological characteristics, important progress was made not only in differentiating these subtypes, but also in understanding—and treating—their eponymous manifestations.
    Mesh-Begriff(e) Antibodies, Antineutrophil Cytoplasmic/blood ; Antibodies, Monoclonal, Murine-Derived/therapeutic use ; Granulomatosis with Polyangiitis/blood ; Granulomatosis with Polyangiitis/classification ; Granulomatosis with Polyangiitis/diagnosis ; Granulomatosis with Polyangiitis/drug therapy ; Humans ; Immunologic Factors/therapeutic use ; Neural Networks, Computer ; Rituximab ; Terminology as Topic ; Vasculitis/blood ; Vasculitis/classification ; Vasculitis/diagnosis ; Vasculitis/drug therapy
    Chemische Substanzen Antibodies, Antineutrophil Cytoplasmic ; Antibodies, Monoclonal, Murine-Derived ; Immunologic Factors ; Rituximab (4F4X42SYQ6)
    Sprache Englisch
    Erscheinungsdatum 2012-01-10
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2491532-4
    ISSN 1759-4804 ; 1759-4790
    ISSN (online) 1759-4804
    ISSN 1759-4790
    DOI 10.1038/nrrheum.2011.218
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  10. Artikel ; Online: Pathogenesis of anti-neutrophil cytoplasmic antibody-associated vasculitis: challenges and solutions 2014.

    Schönermarck, Ulf / Csernok, Elena / Gross, Wolfgang L

    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association

    2015  Band 30 Suppl 1, Seite(n) i46–52

    Abstract: Anti-neutrophil cytoplasmic autoantibodies (ANCA) with specificity for proteinase 3 (PR3-ANCA) or myeloperoxidase (MPO-ANCA) are a defining feature of ANCA-associated vasculitides (AAV). They play a pivotal role in disease pathophysiology and have ... ...

    Abstract Anti-neutrophil cytoplasmic autoantibodies (ANCA) with specificity for proteinase 3 (PR3-ANCA) or myeloperoxidase (MPO-ANCA) are a defining feature of ANCA-associated vasculitides (AAV). They play a pivotal role in disease pathophysiology and have strongly improved early diagnosis and treatment of these infrequent, but potentially fatal diseases. Neutrophils and their products are major players in initiating the autoimmune response and tissue destruction in vasculitic as well as granulomatous inflammation. This review highlights recent findings on old and novel players (ANCA, neutrophils, neutrophil extracellular traps, fibroblasts, immune cells and complement) and puts them into context with the current understanding of disease mechanisms in AAV.
    Mesh-Begriff(e) Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis/etiology ; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis/immunology ; Autoimmunity/immunology ; Complement System Proteins/immunology ; Humans ; Neutrophils/immunology
    Chemische Substanzen Complement System Proteins (9007-36-7)
    Sprache Englisch
    Erscheinungsdatum 2015-04
    Erscheinungsland England
    Dokumenttyp Journal Article ; Review
    ZDB-ID 90594-x
    ISSN 1460-2385 ; 0931-0509
    ISSN (online) 1460-2385
    ISSN 0931-0509
    DOI 10.1093/ndt/gfu398
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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