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  1. Artikel: Traumatic lumbar spondylolisthesis: A case report and review of literature.

    Adjiou, François de Paule Dognon Kossi / Hakkou, El Mehdi / Abbas, Salma / El Manouni, Othmane / Kajeou, Meriem / El Ouahabi, Abdessamad

    Journal of neurosciences in rural practice

    2024  Band 15, Heft 2, Seite(n) 377–380

    Abstract: Traumatic spondylolisthesis of the lumbosacral junction (SPL) is a spinal injury rarely seen in current practice. Few cases are reported in the literature. It arises from complex trauma of high-energy mechanisms. We discussed the case of a young patient. ...

    Abstract Traumatic spondylolisthesis of the lumbosacral junction (SPL) is a spinal injury rarely seen in current practice. Few cases are reported in the literature. It arises from complex trauma of high-energy mechanisms. We discussed the case of a young patient. He is 24 years old without notable pathological history victim of a traffic road accident. Clinically, he has no sensory or motor deficit, it is a spinal trauma classified American spinal injury association E (ASIA E) with severe back pain. A whole-body CT scan performed on admission showed a grade 2 L5-S1 SPL. A lumbar MRI revealed a tear of the disc at L5-S1. We performed a laminectomy to decompress the dural sheath and cauda equina roots with transforaminal lumbar interbody fusion. A postoperative CT scan showed the reduction of the spondylolisthesis. Two months later, the patient resumed walking. Surgery is the gold standard for the management of traumatic SPL. The aim of surgery is to achieve neural structure decompression and obtain stability with fusion.
    Sprache Englisch
    Erscheinungsdatum 2024-02-13
    Erscheinungsland United States
    Dokumenttyp Case Reports
    ZDB-ID 2601242-X
    ISSN 0976-3155 ; 0976-3147
    ISSN (online) 0976-3155
    ISSN 0976-3147
    DOI 10.25259/JNRP_330_2023
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Glioma dataset from Rabat: Clinicopathological, immunohistochemical and disease progression features of 32 Moroccan patients with diffuse Glioma.

    Sfifou, Fatima / Ouzir, Mounir / Hakkou, El Mehdi / Obtel, Majdouline / Errihani, Hassan / Bouzidi, Abderrahmane Al / Abouqal, Redouane / Ouahabi, Abdessamad El / Cherradi, Nadia

    Data in brief

    2022  Band 42, Seite(n) 108265

    Abstract: The Moroccan Glioma Dataset contains the clinical data of 32 patients with glioma. The clinical data including demographic data (age, sex), tumor characteristics (tumor location, Glioma type, Karnofsky performance score, mitotic activity, cell density, ... ...

    Abstract The Moroccan Glioma Dataset contains the clinical data of 32 patients with glioma. The clinical data including demographic data (age, sex), tumor characteristics (tumor location, Glioma type, Karnofsky performance score, mitotic activity, cell density, necrosis, endotheliocapillary vascular proliferation, MRI contrast pick-up, corpus collosum infiltration and Oedema), treatment strategy (subtotal resection, gross resection, biopsy, radiotherapy, chemotherapy), expression pattern of tumor biomarkers (IDH1, HIF-1alpha, P53, Ki-67), and survival data (Kaplan-Meier curves for disease progression). The dataset can be used to relate tumor characteristics to tumor biomarkers and to predict disease progression for a better treatment management. The data were presented, analyzed, and described in the article "Immunohistochemical expression of HIF-1α, IDH1 and TP53: prognostic profile of Moroccan patients with diffuse glioma" published in Journal of Chemical Neuroanatomy [1].
    Sprache Englisch
    Erscheinungsdatum 2022-05-12
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article
    ZDB-ID 2786545-9
    ISSN 2352-3409 ; 2352-3409
    ISSN (online) 2352-3409
    ISSN 2352-3409
    DOI 10.1016/j.dib.2022.108265
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel: Glioma dataset from Rabat: Clinicopathological, immunohistochemical and disease progression features of 32 Moroccan patients with diffuse Glioma

    Sfifou, Fatima / Ouzir, Mounir / Hakkou, El Mehdi / Obtel, Majdouline / Errihani, Hassan / Bouzidi, Abderrahmane Al / Abouqal, Redouane / Ouahabi, Abdessamad El / Cherradi, Nadia

    Data in Brief. 2022 June, v. 42

    2022  

    Abstract: The Moroccan Glioma Dataset contains the clinical data of 32 patients with glioma. The clinical data including demographic data (age, sex), tumor characteristics (tumor location, Glioma type, Karnofsky performance score, mitotic activity, cell density, ... ...

    Abstract The Moroccan Glioma Dataset contains the clinical data of 32 patients with glioma. The clinical data including demographic data (age, sex), tumor characteristics (tumor location, Glioma type, Karnofsky performance score, mitotic activity, cell density, necrosis, endotheliocapillary vascular proliferation, MRI contrast pick-up, corpus collosum infiltration and Oedema), treatment strategy (subtotal resection, gross resection, biopsy, radiotherapy, chemotherapy), expression pattern of tumor biomarkers (IDH1, HIF-1alpha, P53, Ki-67), and survival data (Kaplan-Meier curves for disease progression). The dataset can be used to relate tumor characteristics to tumor biomarkers and to predict disease progression for a better treatment management. The data were presented, analyzed, and described in the article “Immunohistochemical expression of HIF-1α, IDH1 and TP53: prognostic profile of Moroccan patients with diffuse glioma” published in Journal of Chemical Neuroanatomy [1].
    Schlagwörter biomarkers ; biopsy ; data collection ; disease progression ; drug therapy ; edema ; glioma ; immunohistochemistry ; mitosis ; necrosis ; radiotherapy ; resection
    Sprache Englisch
    Erscheinungsverlauf 2022-06
    Erscheinungsort Elsevier Inc.
    Dokumenttyp Artikel
    ZDB-ID 2786545-9
    ISSN 2352-3409
    ISSN 2352-3409
    DOI 10.1016/j.dib.2022.108265
    Datenquelle NAL Katalog (AGRICOLA)

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  4. Artikel ; Online: Letter: Neurosurgical Patients' Management During the COVID-19 Pandemic-An Institutional Report From an African Neurosurgical Center.

    Oudrhiri, Mohammed Yassaad / Bechri, Hajar / Hakkou, El Mehdi / Melhaoui, Adyl / Arkha, Yasser / El Ouahabi, Abdessamad

    Neurosurgery

    2020  Band 87, Heft 2, Seite(n) E230–E231

    Schlagwörter covid19
    Sprache Englisch
    Erscheinungsdatum 2020-01-28
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 135446-2
    ISSN 1524-4040 ; 0148-396X
    ISSN (online) 1524-4040
    ISSN 0148-396X
    DOI 10.1093/neuros/nyaa182
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: Letter to the Editor: How the Pandemic Is Changing Neurosurgical Education in Morocco.

    Oudrhiri, Mohammed Yassaad / Bechri, Hajar / Hakkou, El Mehdi / Arkha, Yasser / El Ouahabi, Abdessamad

    World neurosurgery

    2020  Band 140, Seite(n) 474–475

    Mesh-Begriff(e) Betacoronavirus ; COVID-19 ; Coronavirus Infections ; Humans ; Morocco/epidemiology ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2
    Schlagwörter covid19
    Sprache Englisch
    Erscheinungsdatum 2020-06-06
    Erscheinungsland United States
    Dokumenttyp Letter ; Comment
    ZDB-ID 2534351-8
    ISSN 1878-8769 ; 1878-8750
    ISSN (online) 1878-8769
    ISSN 1878-8750
    DOI 10.1016/j.wneu.2020.05.281
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel ; Online: Immunohistochemical expression of HIF-1α, IDH1 and TP53: Prognostic profile of Moroccan patients with diffuse glioma.

    Sfifou, Fatima / Ouzir, Mounir / Hakkou, El Mehdi / Obtel, Majdouline / Errihani, Hassan / Bouzidi, Abderrahmane Al / Abouqal, Redouane / El Ouahabi, Abdessamad / Cherradi, Nadia

    Journal of chemical neuroanatomy

    2021  Band 119, Seite(n) 102056

    Abstract: Diffuse gliomas are growing brain tumors that occur in adult life. This study was designed to determine whether the immunohistochemical analysis of IDH1, HIF-1alpha, or TP53 can provide useful biomarkers of clinical severity and progression of diffuse ... ...

    Abstract Diffuse gliomas are growing brain tumors that occur in adult life. This study was designed to determine whether the immunohistochemical analysis of IDH1, HIF-1alpha, or TP53 can provide useful biomarkers of clinical severity and progression of diffuse gliomas. Also, it is hypothesized that the expression of IDH1 mutant induces HIF-1alpha. Immunohistochemical staining for HIF-1alpha, IDH1, and TP 53 was performed in biopsy or resection (sub-total or gross-total) tissue from diffuse gliomas in a clinical series of 32 patients. Associations of the HIF-1alpha, IDH1, and TP53 with clinical characteristics were evaluated and the co-expression of two biomarkers (HIF-1alpha and IDH1) was tested. Our data revealed that each biomarker is expressed in a subset of gliomas (IDH1 was positive in 56% cases, HIF-1alpha was positive in 50% cases and TP53 was positive in 44% cases). While no associations were found between clinical characteristics and the expression of HIF-1alpha, and TP53, IDH1 expression was associated with less severe clinical presentation (Karnofsky Performance Status) and disease progression and was more often expressed in females than males. In addition, there was no clear association between IDH1 and HIF-1alpha expression (21.9% of patients co-expressed IDH1 and HIF-1alpha). The current series provides clinical and immunohistochemical findings that can be useful for the clinical management of patients with diffused gliomas.
    Mesh-Begriff(e) Adult ; Brain Neoplasms/genetics ; Brain Neoplasms/metabolism ; Female ; Glioma/diagnosis ; Glioma/metabolism ; Glioma/pathology ; Humans ; Hypoxia-Inducible Factor 1, alpha Subunit ; Isocitrate Dehydrogenase/genetics ; Isocitrate Dehydrogenase/metabolism ; Male ; Morocco ; Prognosis ; Tumor Suppressor Protein p53/metabolism
    Chemische Substanzen HIF1A protein, human ; Hypoxia-Inducible Factor 1, alpha Subunit ; TP53 protein, human ; Tumor Suppressor Protein p53 ; Isocitrate Dehydrogenase (EC 1.1.1.41) ; IDH1 protein, human (EC 1.1.1.42.)
    Sprache Englisch
    Erscheinungsdatum 2021-12-03
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article
    ZDB-ID 639443-7
    ISSN 1873-6300 ; 0891-0618
    ISSN (online) 1873-6300
    ISSN 0891-0618
    DOI 10.1016/j.jchemneu.2021.102056
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel: Letter to the Editor regarding "COVID-19 and Neurosurgical Education in Africa"; How the pandemic is changing neurosurgical education in Morocco

    Oudrhiri, Mohammed Yassaad / Bechri, Hajar / Hakkou, El Mehdi / Arkha, Yasser / El Ouahabi, Abdessamad

    World neurosurgery (Online)

    Schlagwörter covid19
    Verlag WHO
    Dokumenttyp Artikel
    Anmerkung WHO #Covidence: #548028
    Datenquelle COVID19

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  8. Artikel: Letter: Neurosurgical Patients' Management During the COVID-19 Pandemic-An Institutional Report From an African Neurosurgical Center

    Oudrhiri, Mohammed Yassaad / Bechri, Hajar / Hakkou, El Mehdi / Melhaoui, Adyl / Arkha, Yasser / El Ouahabi, Abdessamad

    Neurosurgery

    Schlagwörter covid19
    Verlag WHO
    Dokumenttyp Artikel
    Anmerkung WHO #Covidence: #155201
    Datenquelle COVID19

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  9. Artikel: Letter to the Editor: How the Pandemic Is Changing Neurosurgical Education in Morocco

    Oudrhiri, Mohammed Yassaad / Bechri, Hajar / Hakkou, El Mehdi / Arkha, Yasser / El Ouahabi, Abdessamad

    World Neurosurg

    Schlagwörter covid19
    Verlag WHO
    Dokumenttyp Artikel
    Anmerkung WHO #Covidence: #548028
    Datenquelle COVID19

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  10. Artikel ; Online: Letter

    Oudrhiri, Mohammed Yassaad / Bechri, Hajar / Hakkou, El Mehdi / Melhaoui, Adyl / Arkha, Yasser / El Ouahabi, Abdessamad

    Neurosurgery

    Neurosurgical Patients’ Management During the COVID-19 Pandemic—An Institutional Report From an African Neurosurgical Center

    2020  Band 87, Heft 2, Seite(n) E230–E231

    Schlagwörter Surgery ; Clinical Neurology ; covid19
    Sprache Englisch
    Verlag Oxford University Press (OUP)
    Erscheinungsland uk
    Dokumenttyp Artikel ; Online
    ZDB-ID 135446-2
    ISSN 1524-4040 ; 0148-396X
    ISSN (online) 1524-4040
    ISSN 0148-396X
    DOI 10.1093/neuros/nyaa182
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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