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  1. Buch ; Dissertation / Habilitation: Einfluss der konstitutiven Aktivierung von STAT3 auf die Induktion und Aufrechterhaltung der leukämischen Stammzelle in der akuten myeloischen Leukämie

    Held, Hannelore

    2016  

    Verfasserangabe vorgelegt von Hannelore Held
    Sprache Deutsch
    Umfang 194 Seiten, Illustrationen, Diagramme
    Erscheinungsort Frankfurt am Main
    Erscheinungsland Deutschland
    Dokumenttyp Buch ; Dissertation / Habilitation
    Dissertation / Habilitation Dissertation, Johann Wolfgang Goethe-Universität Frankfurt am Main, 2017
    Anmerkung Zusammenfassung in deutscher und englischer Sprache
    HBZ-ID HT019625858
    Datenquelle Katalog ZB MED Medizin, Gesundheit

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  2. Artikel ; Online: Intensivmedizinisches Management akuter Aortenerkrankungen.

    Rand, A / Busch, A / Held, H / Reeps, C / Koch, T

    Die Anaesthesiologie

    2023  Band 72, Heft 4, Seite(n) 275–281

    Abstract: Acute aortic diseases represent a group of complex severe and often fatal medical conditions. Although they are significantly rarer than cardiac or thromboembolic events, they are an important differential diagnosis to be ruled out, e.g., in the clinical ...

    Titelübersetzung Intensive care management of acute diseases of the aorta.
    Abstract Acute aortic diseases represent a group of complex severe and often fatal medical conditions. Although they are significantly rarer than cardiac or thromboembolic events, they are an important differential diagnosis to be ruled out, e.g., in the clinical work-up of acute chest pain.Treatment, especially surgical interventions, depends on the progression, extent and size of the pathology and whenever possible should be performed in specialized centers with the appropriate experience.Intensive care monitoring is advisable as a range of peracute complications can occur even in initially stable patients. Depending on the clinical presentation and affected structures, a number of severe complications need to be anticipated by critical care physicians. Additionally, a notable symptom is severe and refractory hypertension, especially in the acute phase. This article provides a summary of the most frequent clinical pictures and corresponding treatment options. Furthermore, the principles of initial patient stabilization and treatment as well as the perioperative management of complex surgical procedures on the aorta are discussed.
    Mesh-Begriff(e) Humans ; Acute Disease ; Aortic Dissection ; Aorta/pathology ; Aortic Diseases/diagnosis ; Critical Care
    Sprache Deutsch
    Erscheinungsdatum 2023-02-03
    Erscheinungsland Germany
    Dokumenttyp English Abstract ; Journal Article ; Review
    ISSN 2731-6866
    ISSN (online) 2731-6866
    DOI 10.1007/s00101-023-01253-9
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Buch ; Dissertation / Habilitation: Detektion von einem differentiell exprimierten Gen in der Ovarialkarzinomzellinie NIH:OVCAR-3

    Held, Holger

    1998  

    Verfasserangabe vorgelegt von Holger Held
    Sprache Deutsch
    Umfang 57 S. : Ill., graph. Darst.
    Dokumenttyp Buch ; Dissertation / Habilitation
    Dissertation / Habilitation Kiel, Univ., Diss., 1998
    HBZ-ID HT008877638
    Datenquelle Katalog ZB MED Medizin, Gesundheit

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  4. Artikel ; Online: Climate targets and cost-effective climate stabilization pathways

    Held H.

    EPJ Web of Conferences, Vol 98, p

    2015  Band 06002

    Abstract: Climate economics has developed two main tools to derive an economically adequate response to the climate problem. Cost benefit analysis weighs in any available information on mitigation costs and benefits and thereby derives an “optimal” global mean ... ...

    Abstract Climate economics has developed two main tools to derive an economically adequate response to the climate problem. Cost benefit analysis weighs in any available information on mitigation costs and benefits and thereby derives an “optimal” global mean temperature. Quite the contrary, cost effectiveness analysis allows deriving costs of potential policy targets and the corresponding cost- minimizing investment paths. The article highlights pros and cons of both approaches and then focusses on the implications of a policy that strives at limiting global warming to 2 °C compared to pre-industrial values. The related mitigation costs and changes in the energy sector are summarized according to the IPCC report of 2014. The article then points to conceptual difficulties when internalizing uncertainty in these types of analyses and suggests pragmatic solutions. Key statements on mitigation economics remain valid under uncertainty when being given the adequate interpretation. Furthermore, the expected economic value of perfect climate information is found to be on the order of hundreds of billions of Euro per year if a 2°-policy were requested. Finally, the prospects of climate policy are sketched.
    Schlagwörter Science ; Q ; Physics ; QC1-999
    Sprache Englisch
    Erscheinungsdatum 2015-01-01T00:00:00Z
    Verlag EDP Sciences
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  5. Artikel: Cost Risk Analysis: Dynamically Consistent Decision-Making under Climate Targets

    Held, Hermann

    Environmental and resource economics. 2019 Jan., v. 72, no. 1

    2019  

    Abstract: Cost risk analysis (CRA) is currently emerging as a noticed decision-analytic framework within the field of climate economics. It combines the expected utility-based structure of cost–benefit analysis with the target-based approach of cost effectiveness ... ...

    Abstract Cost risk analysis (CRA) is currently emerging as a noticed decision-analytic framework within the field of climate economics. It combines the expected utility-based structure of cost–benefit analysis with the target-based approach of cost effectiveness analysis (CEA). As such, it offers a promising candidate for those decision-makers who would like to express their precautionary attitude in view of deeply uncertain global warming impacts through a temperature target, yet who would like to avoid the dynamic inconsistencies of CEA. We review both its rationale and key results derived from it. (1) Without a delay in mitigation policy as against the CRA-optimal solution, CRA produces solutions resembling those obtained by means of cost effectiveness analysis, thereby retroactively justifying the approach underlying the nearly 1000 scenarios gathered in IPCC AR5. (2) With an increasing delay, however, CRA would result in decreasing mitigation costs, contrary to CEA. (3) CRA has demonstrated that it is possible to determine the economic value of climate information, unlike CEA. Here, for the first time, a complete list of the assumptions on which CRA is based is presented, including a missing proof. In closing, we explain finding (1) and thereby also show that, without a delay, CRA-based solutions are universal in that they essentially do not depend on the choice of a ‘risk function.’
    Schlagwörter climate ; cost benefit analysis ; cost effectiveness ; decision making ; economic valuation ; environmental economics ; environmental policy ; global warming ; risk ; risk analysis ; temperature
    Sprache Englisch
    Erscheinungsverlauf 2019-01
    Umfang p. 247-261.
    Erscheinungsort Springer Netherlands
    Dokumenttyp Artikel
    ZDB-ID 1479788-4
    ISSN 1573-1502 ; 0924-6460
    ISSN (online) 1573-1502
    ISSN 0924-6460
    DOI 10.1007/s10640-018-0288-y
    Datenquelle NAL Katalog (AGRICOLA)

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  6. Artikel ; Online: Climate policy options and the transformation of the energy system

    Held H.

    EPJ Web of Conferences, Vol 54, p

    2013  Band 01002

    Abstract: The key lines of argument to estimate a meaningful degree of efforts to mitigate global warming are outlined. Potential implementations of a policy that strives to limit global warming to 2°C compared to pre-industrial values are discussed. A recent ... ...

    Abstract The key lines of argument to estimate a meaningful degree of efforts to mitigate global warming are outlined. Potential implementations of a policy that strives to limit global warming to 2°C compared to pre-industrial values are discussed. A recent model intercomparison study on mitigation costs is summarized. Conceptual difficulties when internalizing uncertainty in these types of analyses are highlighted and first attempts to overcome them are outlined. For the mitigation technology “carbon capture and storage” it is illustrated that mitigation technologies also require a proper treatment of their side-effects rather than just focusing on their cost-reduction potential in the context of mitigation. Finally, the prospects of climate policy are sketched.
    Schlagwörter Physics ; QC1-999 ; Science ; Q ; DOAJ:Physics (General) ; DOAJ:Physics and Astronomy
    Sprache Englisch
    Erscheinungsdatum 2013-06-01T00:00:00Z
    Verlag EDP Sciences
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  7. Artikel: Die Kosten des 2°-Ziels und seine klimapolitischen Herausforderungen

    Held, Hermann

    Die Nutzung von Ressourcen - mehr als eine ökonomische Fragestellung : vierte wissenschaftliche Tagung Economic Governance und Ordonomik : Beiträge zur Tagung 2016 im Festsaal des Siedehauses des Technischen Halloren- und Salinemuseums , p. 177-188

    2017  , Seite(n) 177–188

    Verfasserangabe Hermann Held
    Schlagwörter Klimaschutz ; Nachhaltige Energieversorgung ; Kosteneffizienz
    Sprache Deutsch
    Verlag Lehrstuhl für Wirtschaftspolitik und Wirtschaftsforschung, Martin-Luther-Universität Halle-Wittenberg
    Erscheinungsort Halle (Saale)
    Dokumenttyp Artikel
    ISBN 978-3-86829-870-3 ; 3-86829-870-3
    Datenquelle ECONomics Information System

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  8. Artikel: Schockraummanagement

    Mibelli, Nicolas / Kamin, Konrad / Gondert, Markus M. / Held, Hanns-Christoph

    Allgemein- und Viszeralchirurgie up2date

    2023  Band 17, Heft 05, Seite(n) 385–405

    Schlagwörter Notfallmedizin ; Polytrauma ; ABCDE-Schema ; Blutungskontrolle ; Verbrennung
    Sprache Deutsch
    Erscheinungsdatum 2023-09-29
    Verlag Georg Thieme Verlag KG
    Erscheinungsort Stuttgart ; New York
    Dokumenttyp Artikel
    ZDB-ID 2317051-7
    ISSN 1611-6461 ; 1611-6437
    ISSN (online) 1611-6461
    ISSN 1611-6437
    DOI 10.1055/a-2099-3327
    Datenquelle Thieme Verlag

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  9. Buch ; Dissertation / Habilitation: Sedimentation bei 1 [ein] g von menschlichen Blut- und Knochenmarkszellen zur Differenzierung von Lymphocyten und Stammzellen

    Held, Harald

    1983  

    Titelvarianten Sedimentation bei 1 g von menschlichen Blut- und Knochenmarkszellen zur Differenzierung von Lymphocyten und Stammzellen
    Umfang 56 S. : Ill., graph. Darst.
    Dokumenttyp Buch ; Dissertation / Habilitation
    Dissertation / Habilitation Kiel, Univ., Diss., 1983
    HBZ-ID HT002134782
    Datenquelle Katalog ZB MED Medizin, Gesundheit

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  10. Artikel: Giftige Verwandtschaft. Versuch der Herbeiführung einer Boraxintoxikation? Toxic relatives. Attempted poisoning with borax?

    Plenzig, S. / Held, H. / Verhoff, M. A.

    Rechtsmedizin

    2019  Band 29, Heft 3, Seite(n) 209

    Sprache Deutsch
    Dokumenttyp Artikel
    ZDB-ID 1064911-6
    ISSN 0937-9819
    Datenquelle Current Contents Medizin

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