Artikel: Characterization of
2021 Band 12, Seite(n) 613808
Abstract: The SALL2 transcription factor, an evolutionarily conserved gene through vertebrates, is involved in normal development and neuronal differentiation. In disease, SALL2 is associated with eye, kidney, and brain disorders, but mainly is related to cancer. ... ...
Abstract | The SALL2 transcription factor, an evolutionarily conserved gene through vertebrates, is involved in normal development and neuronal differentiation. In disease, SALL2 is associated with eye, kidney, and brain disorders, but mainly is related to cancer. Some studies support a tumor suppressor role and others an oncogenic role for SALL2, which seems to depend on the cancer type. An additional consideration is tissue-dependent expression of different SALL2 isoforms. Human and mouse |
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Sprache | Englisch |
Erscheinungsdatum | 2021-02-22 |
Erscheinungsland | Switzerland |
Dokumenttyp | Journal Article |
ZDB-ID | 2606823-0 |
ISSN | 1664-8021 |
ISSN | 1664-8021 |
DOI | 10.3389/fgene.2021.613808 |
Datenquelle | MEDical Literature Analysis and Retrieval System OnLINE |
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