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Artikel ; Online: Dynamic compartmentalization of the pro-invasive transcription factor NHR-67 reveals a role for Groucho in regulating a proliferative-invasive cellular switch in

Medwig-Kinney, Taylor N / Kinney, Brian A / Martinez, Michael A Q / Yee, Callista / Sirota, Sydney S / Mullarkey, Angelina A / Somineni, Neha / Hippler, Justin / Zhang, Wan / Shen, Kang / Hammell, Christopher / Pani, Ariel M / Matus, David Q

eLife

2023  Band 12

Abstract: A growing body of evidence suggests that cell division and basement membrane invasion are mutually exclusive cellular behaviors. How cells switch between proliferative and invasive states is not well understood. Here, we investigated this dichotomy in ... ...

Abstract A growing body of evidence suggests that cell division and basement membrane invasion are mutually exclusive cellular behaviors. How cells switch between proliferative and invasive states is not well understood. Here, we investigated this dichotomy in vivo by examining two cell types in the developing
Mesh-Begriff(e) Animals ; Basic Helix-Loop-Helix Transcription Factors/metabolism ; Caenorhabditis elegans/metabolism ; Caenorhabditis elegans Proteins/metabolism ; Cell Differentiation ; Gene Expression Regulation ; Transcription Factors/metabolism ; Receptors, Cytoplasmic and Nuclear/metabolism
Chemische Substanzen Basic Helix-Loop-Helix Transcription Factors ; Caenorhabditis elegans Proteins ; HLH-2 protein, C elegans ; Transcription Factors ; Nhr-67 protein, C elegans ; Receptors, Cytoplasmic and Nuclear ; unc-37 protein, C elegans
Sprache Englisch
Erscheinungsdatum 2023-12-01
Erscheinungsland England
Dokumenttyp Journal Article
ZDB-ID 2687154-3
ISSN 2050-084X ; 2050-084X
ISSN (online) 2050-084X
ISSN 2050-084X
DOI 10.7554/eLife.84355
Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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