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  1. Artikel: Evaluation of the Treatment Effects of Intervention in Cortical Watershed Infarction Caused by Middle Cerebral Artery Stenosis.

    Li, Jianjun / Huang, Riming / Li, Jia / Wu, Wei

    Alternative therapies in health and medicine

    2024  

    Abstract: Objective: This study aims to evaluate the efficacy of interventional treatment in patients with hypoperfusion cerebral infarction in the territory of the lenticulostriate arteries caused by middle cerebral artery (MCA) stenosis.: Methods: A ... ...

    Abstract Objective: This study aims to evaluate the efficacy of interventional treatment in patients with hypoperfusion cerebral infarction in the territory of the lenticulostriate arteries caused by middle cerebral artery (MCA) stenosis.
    Methods: A prospective, single-center, non-blinded research design was employed to assess the efficacy of interventional treatment for hypoperfusion cerebral infarction in the territory of the lenticulostriate arteries caused by MCA stenosis. Clinical and surgical data were collected from patients with MCA atherosclerotic disease who underwent interventional therapy at our hospital between January 2020 and December 2022. The intervention group consisted of 8 patients meeting the criteria for hypoperfusion cerebral infarction caused by MCA stenosis, while the control group comprised 8 patients with hypoperfusion cerebral infarction caused by middle cerebral artery stenosis who received conventional treatment. Clinical and imaging characteristics, perioperative complications, and follow-up outcomes were compared between the two groups.
    Results: Pre-intervention cerebral perfusion imaging revealed significantly prolonged rMTT and rTTP, decreased rCBF, and altered rCBV within the territory of the lenticulostriate arteries in all 8 patients. Follow-up imaging showed restoration of blood flow and comparable perfusion to the healthy contralateral side. A case demonstrating successful restoration of vessel patency, good recovery, and absence of complications was presented. Both groups had favorable outcomes during follow-up, with no cases of stroke, transient ischemic attack (TIA), or death in the perioperative period. There were no significant differences in relative perfusion parameters, NIHSS scores, and mRS scores between the two groups.
    Conclusion: Interventional treatment demonstrates good efficacy and low risk of complications in treating cortical watershed cerebral infarction caused by middle cerebral artery stenosis. It is an effective and safe alternative to conventional treatment.
    Sprache Englisch
    Erscheinungsdatum 2024-02-09
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 1225073-9
    ISSN 1078-6791
    ISSN 1078-6791
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Encapsulated starch characteristics and its shell matrix mechanisms controlling starch digestion.

    Kraithong, Supaluck / Theppawong, Atiruj / Huang, Riming

    Food chemistry

    2023  Band 423, Seite(n) 136322

    Abstract: Encapsulated starch can be classified as physically inaccessible starch or type 1 resistant starch (RS1), which is produced by encapsulating starch granules within food matrices using various encapsulation techniques. Encapsulated starch has the ... ...

    Abstract Encapsulated starch can be classified as physically inaccessible starch or type 1 resistant starch (RS1), which is produced by encapsulating starch granules within food matrices using various encapsulation techniques. Encapsulated starch has the potential to be used as a functional ingredient in low-/medium-glycemic index (GI) foods as it can help control glycemic and insulin responses. Despite its remarkable benefits, the relevant information related to entrapped starch and its application is still insufficient and needs further elucidation. The objective of this work is to present a comprehensive overview of the current techniques utilized for the preparation of encapsulated starch and its characteristics, thereby extending the fundamental knowledge. Furthermore, this review delves into the mechanisms governing starch hydrolysis regulated by shell matrices and provides the prospective utilization of encapsulated starch in food production.
    Mesh-Begriff(e) Starch ; Prospective Studies ; Insulin ; Food ; Digestion ; Glycemic Index
    Chemische Substanzen Starch (9005-25-8) ; Insulin
    Sprache Englisch
    Erscheinungsdatum 2023-05-12
    Erscheinungsland England
    Dokumenttyp Journal Article ; Review
    ZDB-ID 243123-3
    ISSN 1873-7072 ; 0308-8146
    ISSN (online) 1873-7072
    ISSN 0308-8146
    DOI 10.1016/j.foodchem.2023.136322
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Diversified Chemical Structures and Bioactivities of the Chemical Constituents Found in the Brown Algae Family Sargassaceae.

    Peng, Yan / Yang, Xianwen / Huang, Riming / Ren, Bin / Chen, Bin / Liu, Yonghong / Zhang, Hongjie

    Marine drugs

    2024  Band 22, Heft 2

    Abstract: Sargassaceae, the most abundant family in Fucales, was recently formed through the merging of the two former families Sargassaceae and Cystoseiraceae. It is widely distributed in the world's oceans, notably in tropical coastal regions, with the exception ...

    Abstract Sargassaceae, the most abundant family in Fucales, was recently formed through the merging of the two former families Sargassaceae and Cystoseiraceae. It is widely distributed in the world's oceans, notably in tropical coastal regions, with the exception of the coasts of Antarctica and South America. Numerous bioactivities have been discovered through investigations of the chemical diversity of the Sargassaceae family. The secondary metabolites with unique structures found in this family have been classified as terpenoids, phlorotannins, and steroids, among others. These compounds have exhibited potent pharmacological activities. This review describes the new discovered compounds from Sargassaceae species and their associated bioactivities, citing 136 references covering from March 1975 to August 2023.
    Mesh-Begriff(e) Humans ; Phaeophyceae ; Oceans and Seas ; Antarctic Regions
    Sprache Englisch
    Erscheinungsdatum 2024-01-24
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2175190-0
    ISSN 1660-3397 ; 1660-3397
    ISSN (online) 1660-3397
    ISSN 1660-3397
    DOI 10.3390/md22020059
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel ; Online: Advancements in understanding low starch hydrolysis in pigmented rice: A comprehensive overview of mechanisms.

    Kraithong, Supaluck / Theppawong, Atiruj / Bunyameen, Nasuha / Zhang, Xiaoyong / Huang, Riming

    Food chemistry

    2023  Band 439, Seite(n) 138079

    Abstract: This review explores the health-promoting properties of pigmented rice, focusing on its unique ability to promote slow starch digestion and improve blood sugar regulation. While the impact of slow starch digestibility is widely acknowledged, our current ... ...

    Abstract This review explores the health-promoting properties of pigmented rice, focusing on its unique ability to promote slow starch digestion and improve blood sugar regulation. While the impact of slow starch digestibility is widely acknowledged, our current understanding of the underlying mechanisms remains insufficient. Therefore, this review aims to bridge the gap by examining the intricate factors and mechanisms that contribute to the low starch hydrolysis of pigmented rice to better understand how it promotes slower starch digestion and improves blood sugar regulation. This paves the way for future advancements in utilizing pigmented rice by enhancing our understanding of the mechanisms behind low starch hydrolysis. These may include the development of food products aimed at mitigating hyperglycemic symptoms and reducing the risk of diabetes. This research broadens our understanding of pigmented rice and facilitates the development of strategies to promote health outcomes by incorporating pigmented rice into our diets.
    Mesh-Begriff(e) Starch ; Hydrolysis ; Oryza ; Blood Glucose ; Health Promotion ; Digestion
    Chemische Substanzen Starch (9005-25-8) ; Blood Glucose
    Sprache Englisch
    Erscheinungsdatum 2023-11-30
    Erscheinungsland England
    Dokumenttyp Journal Article ; Review
    ZDB-ID 243123-3
    ISSN 1873-7072 ; 0308-8146
    ISSN (online) 1873-7072
    ISSN 0308-8146
    DOI 10.1016/j.foodchem.2023.138079
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  5. Artikel: Identification and Structure-Activity Relationship of Recovered Phenolics with Antioxidant and Antihyperglycemic Potential from Sugarcane Molasses Vinasse.

    Huang, Zhe / Chen, Yinning / Huang, Riming / Zhao, Zhengang

    Foods (Basel, Switzerland)

    2022  Band 11, Heft 19

    Abstract: Sugarcane molasses vinasse is the residue of the fermentation of molasses and the water and soil environmental pollutants from distilleries. However, its recycling value has been neglected. The chemical analysis of the molasses vinasse led to the ... ...

    Abstract Sugarcane molasses vinasse is the residue of the fermentation of molasses and the water and soil environmental pollutants from distilleries. However, its recycling value has been neglected. The chemical analysis of the molasses vinasse led to the isolation of a new benzoyl chloride called 2,3,4-trihydroxy-5-methoxy benzoyl chloride, as well as thirteen known compounds, including six benzoic acids. The structure of the new benzoyl chloride was elucidated on the basis of extensive spectroscopic analysis. The antioxidant activity of all isolated compounds was measured using the ORAC assay. Moreover, we compared the cellular antioxidant activity (CAA) and inhibitory activity against α-amylase and α-glucosidase for structure-activity analysis. The results showed that only vanillic acid had CAA (8.64 μmol QE/100 μmol in the no PBS wash protocol and 6.18 μmol QE/100 μmol in the PBS wash protocol), although other benzoic acid derivatives had high ORAC values ranging between 1879.9 and 32,648.1 μmol TE/g. Additional methoxy groups at the
    Sprache Englisch
    Erscheinungsdatum 2022-10-08
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2704223-6
    ISSN 2304-8158
    ISSN 2304-8158
    DOI 10.3390/foods11193131
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  6. Artikel ; Online: Anti-Inflammatory and Gut Microbiota Modulation Potentials of Flavonoids Extracted from Passiflora foetida Fruits

    Han, Xiangpeng / Song, Ya / Huang, Riming / Zhu, Minqian / Li, Meiying / Requena, Teresa / Wang, Hong

    Foods. 2023 July 29, v. 12, no. 15

    2023  

    Abstract: This study aimed to explore the anti-inflammatory and gut microbiota modulation potentials of flavonoid-rich fraction (PFF) extracted from Passiflora foetida fruits. The results showed that PFF markedly reduced the production of nitric oxide (NO), tumor ... ...

    Abstract This study aimed to explore the anti-inflammatory and gut microbiota modulation potentials of flavonoid-rich fraction (PFF) extracted from Passiflora foetida fruits. The results showed that PFF markedly reduced the production of nitric oxide (NO), tumor necrosis factor α (TNF-α), and interleukin 6 (IL-6) in LPS-stimulated RAW 264.7 cells. Meanwhile, PFF treatment also effectively decreased the phosphorylation levels of MAPK, PI3K/Akt, and NF-κB signaling-pathway-related proteins (ERK, JNK, p38, Akt, and p65). Moreover, PFF had an impact on microbial composition and metabolites in a four-stage dynamic simulator of human gut microbiota (BFBL gut model). Specifically, PFF exhibited the growth-promoting ability of several beneficial bacteria, including Bifidobacterium, Enterococcus, Lactobacillus, and Roseburia, and short-chain fatty acid (SCFA) generation ability in gut microbiota. In addition, spectroscopic data revealed that PFF mainly contained five flavonoid compounds, which may be bioactive compounds with anti-inflammatory and gut microbiota modulation potentials. Therefore, PFF could be utilized as a natural anti-inflammatory agent or supplement to health products.
    Schlagwörter Bifidobacterium ; Enterococcus ; Lactobacillus ; Passiflora foetida ; Roseburia ; anti-inflammatory agents ; digestive system ; flavonoids ; humans ; interleukin-6 ; intestinal microorganisms ; metabolites ; models ; nitric oxide ; phosphorylation ; short chain fatty acids ; spectral analysis ; tumor necrosis factors
    Sprache Englisch
    Erscheinungsverlauf 2023-0729
    Erscheinungsort Multidisciplinary Digital Publishing Institute
    Dokumenttyp Artikel ; Online
    ZDB-ID 2704223-6
    ISSN 2304-8158
    ISSN 2304-8158
    DOI 10.3390/foods12152889
    Datenquelle NAL Katalog (AGRICOLA)

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  7. Artikel: Understanding of hydrocolloid functions for enhancing the physicochemical features of rice flour and noodles

    Kraithong, Supaluck / Theppawong, Atiruj / Lee, Suyong / Huang, Riming

    Food hydrocolloids

    2023  Band 142, Heft 142, Seite(n) 108821

    Sprache Englisch
    Dokumenttyp Artikel
    ZDB-ID 742742-6
    ISSN 0268-005X
    Datenquelle Current Contents Ernährung, Umwelt, Agrar

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  8. Artikel ; Online: Curcumin Alleviates Arsenic Trioxide–Induced Inflammation and Pyroptosis via the NF-κB/NLRP3 Signaling Pathway in the Hypothalamus of Ducks

    Gan, Rao / Liu, Haiyan / Wu, Shaofeng / Huang, Riming / Tang, Zhaoxin / Zhang, Ning / Hu, Lianmei

    Biol Trace Elem Res. 2023 May, v. 201, no. 5 p.2503-2511

    2023  

    Abstract: Arsenic (As) as a neurotoxic environmental pollutant has attracted extensive attention. Curcumin (Cur) is a natural antioxidant that shows an excellent protective effect against arsenic trioxide (ATO)–induced toxicity in many animal organs. However, the ... ...

    Abstract Arsenic (As) as a neurotoxic environmental pollutant has attracted extensive attention. Curcumin (Cur) is a natural antioxidant that shows an excellent protective effect against arsenic trioxide (ATO)–induced toxicity in many animal organs. However, the mechanism of Cur against ATO-induced hypothalamic toxicity in ducks has not yet been fully elucidated. Here, ducks were treated with ATO and/or Cur during 28 days; the results showed that ATO exposure induced growth retardation, messy feathers, and abnormal posture in ducks. Moreover, ATO caused neuron vacuolar degeneration and disintegration in the hypothalamus of ducks. Simultaneously, ATO induced blood–brain barrier damage, downregulated the expression of ZO-1, Occludin, and mediated NF‐κB activation, resulting in an increase in inflammatory factors (TLR-4, NF-κB, TNF-α, IL-2, and IL-6). Furthermore, ATO increased the production of pyroptosis-related factors (Caspase-1, IL-18, IL-1), exacerbating the inflammatory damage through NLRP3-mediated inflammasome activation. Cur, on the other hand, exerted excellent inhibitory effects on inflammation and pyroptosis. In summary, our study revealed that ATO triggered inflammation and pyroptosis by modulating NF-κB/NLRP3 signaling pathways in the hypothalamus of ducks, and Cur can alleviate inflammation and pyroptosis caused by ATO. Therefore, as a plant extract, Cur has the potential to prevent and cure ATO-induced hypothalamus toxicity.
    Schlagwörter animals ; antioxidants ; arsenic ; arsenic oxide ; blood-brain barrier ; caspase-1 ; curcumin ; growth retardation ; hypothalamus ; inflammasomes ; inflammation ; interleukin-1 ; interleukin-18 ; interleukin-2 ; interleukin-6 ; neurons ; neurotoxicity ; occludins ; plant extracts ; pollutants ; posture ; protective effect ; pyroptosis ; vacuoles
    Sprache Englisch
    Erscheinungsverlauf 2023-05
    Umfang p. 2503-2511.
    Erscheinungsort Springer US
    Dokumenttyp Artikel ; Online
    ZDB-ID 445336-0
    ISSN 1559-0720 ; 0163-4984
    ISSN (online) 1559-0720
    ISSN 0163-4984
    DOI 10.1007/s12011-022-03321-4
    Datenquelle NAL Katalog (AGRICOLA)

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  9. Artikel ; Online: Structural characterization and ferroptosis-related immunomodulatory of a novel exopolysaccharide isolated from marine fungus Aspergillus medius.

    Yang, Jiajia / Liu, Jun / Kuang, Weiyang / Lin, Yuqi / Zhong, Saiyi / Kraithong, Supaluck / Zhang, Xiaoyong / Wong, Io Nam / Huang, Riming

    International journal of biological macromolecules

    2024  Band 265, Heft Pt 1, Seite(n) 130703

    Abstract: Marine fungal exopolysaccharides play a crucial role in immunoregulation. In this investigation, a novel polysaccharide was extracted from the culture medium of the marine fungus Aspergillus medius SCAU-236. Compositional analysis revealed a structure ... ...

    Abstract Marine fungal exopolysaccharides play a crucial role in immunoregulation. In this investigation, a novel polysaccharide was extracted from the culture medium of the marine fungus Aspergillus medius SCAU-236. Compositional analysis revealed a structure composed of glucose units with (1,4)-α-D-Glcp, (1,3,4)-β-D-Glcp, and (1,4,6)-α-D-Glcp, along with side chains of 1-α-D-Glcp linked to carbon 6 of (1,4,6)-α-D-Glcp and carbon 3 of (1,3,4)-β-D-Glcp. Functional evaluations on RAW264.7 macrophage cells demonstrated Aspergillus medius polysaccharide (ASMP)'s effects on cell proliferation, nitric oxide levels, and the secretion of TNF-α, IL-6, and IL-1β cytokines. Additionally, metabolomics indicated ASMP's potential to modulate macrophage immune function by impacting key regulatory molecules, including COX-2, iNOS, Nrf2, SLC7A11, GPX4, and ACSL4. The Nrf2/SLC7A11/GPX4 axis and ACSL4 were suggested to be involved in ASMP-induced ferroptosis, leading to increased reactive oxygen species (ROS) levels and lipid peroxidation. These findings propose a unique mechanism by which ASMP exerts immunomodulatory effects through ferroptosis induction, contributing to the understanding of marine-derived compounds in immunomodulation research.
    Mesh-Begriff(e) Animals ; Mice ; NF-E2-Related Factor 2 ; Ferroptosis ; Aspergillus/chemistry ; Polysaccharides/chemistry ; RAW 264.7 Cells ; Immunity ; Immunomodulation ; Carbon ; Adenosine Monophosphate/analogs & derivatives ; Thionucleotides
    Chemische Substanzen 5'-deoxy-5'-thioadenosine 5'-monophosphate (55036-25-4) ; NF-E2-Related Factor 2 ; Polysaccharides ; Carbon (7440-44-0) ; Adenosine Monophosphate (415SHH325A) ; Thionucleotides
    Sprache Englisch
    Erscheinungsdatum 2024-03-06
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article
    ZDB-ID 282732-3
    ISSN 1879-0003 ; 0141-8130
    ISSN (online) 1879-0003
    ISSN 0141-8130
    DOI 10.1016/j.ijbiomac.2024.130703
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  10. Artikel ; Online: Colon cancer inhibitory properties of Caulerpa lentillifera polysaccharide and its molecular mechanisms based on three-dimensional cell culture model.

    Xia, Xuewei / Wu, Yulin / Chen, Zexin / Du, Danyi / Chen, Xiaodan / Zhang, Rongxin / Yan, Jun / Wong, Io Nam / Huang, Riming

    International journal of biological macromolecules

    2024  Band 267, Heft Pt 1, Seite(n) 131574

    Abstract: Caulerpa lentillifera is rich in polysaccharides, and its polysaccharides show a significant effect in different biological activities including anti-cancer activity. As an edible algae-derived polysaccharide, exploring the role of colon cancer can ... ...

    Abstract Caulerpa lentillifera is rich in polysaccharides, and its polysaccharides show a significant effect in different biological activities including anti-cancer activity. As an edible algae-derived polysaccharide, exploring the role of colon cancer can better develop the application from a dietary therapy perspective. However, more in-depth studies of C. lentillifera polysaccharide on anti-colon cancer activity and mechanism are needed. In this study, we found that Caulerpa lentillifera polysaccharides (CLP) showed potential anti-colon cancer effect on human colon cancer cell HT29 in monolayer (IC
    Mesh-Begriff(e) Humans ; Polysaccharides/pharmacology ; Polysaccharides/chemistry ; Colonic Neoplasms/drug therapy ; Colonic Neoplasms/metabolism ; Colonic Neoplasms/pathology ; Caulerpa/chemistry ; Spheroids, Cellular/drug effects ; Spheroids, Cellular/metabolism ; Cell Culture Techniques, Three Dimensional/methods ; Cell Proliferation/drug effects ; HT29 Cells ; Cell Line, Tumor ; HCT116 Cells ; Gene Expression Regulation, Neoplastic/drug effects ; Edible Seaweeds
    Chemische Substanzen Polysaccharides
    Sprache Englisch
    Erscheinungsdatum 2024-04-12
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article
    ZDB-ID 282732-3
    ISSN 1879-0003 ; 0141-8130
    ISSN (online) 1879-0003
    ISSN 0141-8130
    DOI 10.1016/j.ijbiomac.2024.131574
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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