Artikel ; Online: EphB4 and ephrinB2 act in opposition in the head and neck tumor microenvironment
Nature Communications, Vol 13, Iss 1, Pp 1-
2022 Band 21
Abstract: EphrinB2 and its receptor EphB4 are highly expressed in head and neck squamous cell carcinoma (HNSCC) and disrupting EphB4-ephrinB2 interaction generates sub-optimal outcomes. Here, compartmental targeting of EphB4 and ephrinB2 in HNSCC cancer cell and ... ...
| Abstract | EphrinB2 and its receptor EphB4 are highly expressed in head and neck squamous cell carcinoma (HNSCC) and disrupting EphB4-ephrinB2 interaction generates sub-optimal outcomes. Here, compartmental targeting of EphB4 and ephrinB2 in HNSCC cancer cell and endothelial compartments suggests that ephrinB2 acts as a tumor promoter and EphB4 as a tumor suppressor. |
|---|---|
| Schlagwörter | Science ; Q |
| Sprache | Englisch |
| Erscheinungsdatum | 2022-06-01T00:00:00Z |
| Verlag | Nature Portfolio |
| Dokumenttyp | Artikel ; Online |
| Datenquelle | BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl) |
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