Artikel ; Online: Continuous glucose monitoring systems in well-controlled children with type 1 diabetes mellitus.
Pediatric endocrinology, diabetes, and metabolism
2023 Band 27, Heft 3, Seite(n) 151–158
Abstract: Introduction: Numerous studies have demonstrated the clinical benefits of using continuous glucose monitoring (CGM) systems among patients with type 1 diabetes (T1D). Aim of the study was to assess the effectiveness of CGM on metabolic control in ... ...
| Titelübersetzung | Zastosowanie systemu ciągłego monitorowania glikemii u dzieci z dobrze kontrolowaną cukrzycą typu 1. |
|---|---|
| Abstract | Introduction: Numerous studies have demonstrated the clinical benefits of using continuous glucose monitoring (CGM) systems among patients with type 1 diabetes (T1D). Aim of the study was to assess the effectiveness of CGM on metabolic control in children with T1D and well-controlled disease prior to the study. Material and methods: This prospective analysis included 99 children (46 girls) at the median age of 11.23 years and diabetes duration of at least 1 year (median: 5.16 years), generally well controlled metabolically (median HbA1c: 7.0%), and treated with continuous subcutaneous insulin infusion (CSII). The patients had used CGM for at least 150 days. We analysed the participants in subgroups based on baseline HbA1c < 7%, ≥ 7%, age, and sex. Results: Children with baseline HbA1c < 7% were characterized by significantly increased HbA1c after the median of 273 days (217; 320) of CGM usage (6.3% vs. 6.6%, respectively; p = 0.002). No significant change in HbA1c was noted in children with baseline HbA1c ≥ 7% (7.5% vs. 7.4%, respectively; p = 0.191), but 20% of the group reached the target of HbA1c < 7.0%. The analysis of CGM data revealed that no group achieved the CGM targets of good metabolic control. Total daily insulin requirements remained stable in both groups (p = 0.752; p = 0.274), but the amount of basal insulin increased statistically in both groups (p = 0.009; p ≤ 0.001). Conclusions: The application of CGM provides detailed information concerning glycaemic control and is beneficial in some, but not all, T1D children with good diabetes control. |
| Mesh-Begriff(e) | Blood Glucose ; Blood Glucose Self-Monitoring ; Child ; Diabetes Mellitus, Type 1/drug therapy ; Female ; Glycated Hemoglobin/analysis ; Humans ; Hypoglycemic Agents/therapeutic use ; Insulin/therapeutic use ; Insulin Infusion Systems |
| Chemische Substanzen | Blood Glucose ; Glycated Hemoglobin A ; Hypoglycemic Agents ; Insulin |
| Sprache | Englisch |
| Erscheinungsdatum | 2023-02-10 |
| Erscheinungsland | Poland |
| Dokumenttyp | Journal Article |
| ZDB-ID | 2617120-X |
| ISSN | 2083-8441 ; 2083-8441 |
| ISSN (online) | 2083-8441 |
| ISSN | 2083-8441 |
| DOI | 10.5114/pedm.2021.107717 |
| Datenquelle | MEDical Literature Analysis and Retrieval System OnLINE |
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