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  1. Artikel ; Online: Crowdsourcing digital health measures to predict Parkinson’s disease severity

    Solveig K. Sieberts / Jennifer Schaff / Marlena Duda / Bálint Ármin Pataki / Ming Sun / Phil Snyder / Jean-Francois Daneault / Federico Parisi / Gianluca Costante / Udi Rubin / Peter Banda / Yooree Chae / Elias Chaibub Neto / E. Ray Dorsey / Zafer Aydın / Aipeng Chen / Laura L. Elo / Carlos Espino / Enrico Glaab /
    Ethan Goan / Fatemeh Noushin Golabchi / Yasin Görmez / Maria K. Jaakkola / Jitendra Jonnagaddala / Riku Klén / Dongmei Li / Christian McDaniel / Dimitri Perrin / Thanneer M. Perumal / Nastaran Mohammadian Rad / Erin Rainaldi / Stefano Sapienza / Patrick Schwab / Nikolai Shokhirev / Mikko S. Venäläinen / Gloria Vergara-Diaz / Yuqian Zhang / the Parkinson’s Disease Digital Biomarker Challenge Consortium / Yuanjia Wang / Yuanfang Guan / Daniela Brunner / Paolo Bonato / Lara M. Mangravite / Larsson Omberg

    npj Digital Medicine, Vol 4, Iss 1, Pp 1-

    the Parkinson’s Disease Digital Biomarker DREAM Challenge

    2021  Band 12

    Abstract: Abstract Consumer wearables and sensors are a rich source of data about patients’ daily disease and symptom burden, particularly in the case of movement disorders like Parkinson’s disease (PD). However, interpreting these complex data into so-called ... ...

    Abstract Abstract Consumer wearables and sensors are a rich source of data about patients’ daily disease and symptom burden, particularly in the case of movement disorders like Parkinson’s disease (PD). However, interpreting these complex data into so-called digital biomarkers requires complicated analytical approaches, and validating these biomarkers requires sufficient data and unbiased evaluation methods. Here we describe the use of crowdsourcing to specifically evaluate and benchmark features derived from accelerometer and gyroscope data in two different datasets to predict the presence of PD and severity of three PD symptoms: tremor, dyskinesia, and bradykinesia. Forty teams from around the world submitted features, and achieved drastically improved predictive performance for PD status (best AUROC = 0.87), as well as tremor- (best AUPR = 0.75), dyskinesia- (best AUPR = 0.48) and bradykinesia-severity (best AUPR = 0.95).
    Schlagwörter Computer applications to medicine. Medical informatics ; R858-859.7
    Thema/Rubrik (Code) 006
    Sprache Englisch
    Erscheinungsdatum 2021-03-01T00:00:00Z
    Verlag Nature Portfolio
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  2. Artikel ; Online: Genome sequences of two diploid wild relatives of cultivated sweetpotato reveal targets for genetic improvement

    Shan Wu / Kin H. Lau / Qinghe Cao / John P. Hamilton / Honghe Sun / Chenxi Zhou / Lauren Eserman / Dorcus C. Gemenet / Bode A. Olukolu / Haiyan Wang / Emily Crisovan / Grant T. Godden / Chen Jiao / Xin Wang / Mercy Kitavi / Norma Manrique-Carpintero / Brieanne Vaillancourt / Krystle Wiegert-Rininger / Xinsun Yang /
    Kan Bao / Jennifer Schaff / Jan Kreuze / Wolfgang Gruneberg / Awais Khan / Marc Ghislain / Daifu Ma / Jiming Jiang / Robert O. M. Mwanga / Jim Leebens-Mack / Lachlan J. M. Coin / G. Craig Yencho / C. Robin Buell / Zhangjun Fei

    Nature Communications, Vol 9, Iss 1, Pp 1-

    2018  Band 12

    Abstract: Sweetpotato is an important food security crop providing rich source of macro- and micronutrients including carbohydrates and vitamins. Here, the authors assemble of the two diploid relatives of cultivated sweetpotato and identify genes and alleles ... ...

    Abstract Sweetpotato is an important food security crop providing rich source of macro- and micronutrients including carbohydrates and vitamins. Here, the authors assemble of the two diploid relatives of cultivated sweetpotato and identify genes and alleles associated with carotenoid biosynthesis from breeding lines.
    Schlagwörter Science ; Q
    Sprache Englisch
    Erscheinungsdatum 2018-11-01T00:00:00Z
    Verlag Nature Publishing Group
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  3. Artikel ; Online: Genome sequences of two diploid wild relatives of cultivated sweetpotato reveal targets for genetic improvement

    Shan Wu / Kin H. Lau / Qinghe Cao / John P. Hamilton / Honghe Sun / Chenxi Zhou / Lauren Eserman / Dorcus C. Gemenet / Bode A. Olukolu / Haiyan Wang / Emily Crisovan / Grant T. Godden / Chen Jiao / Xin Wang / Mercy Kitavi / Norma Manrique-Carpintero / Brieanne Vaillancourt / Krystle Wiegert-Rininger / Xinsun Yang /
    Kan Bao / Jennifer Schaff / Jan Kreuze / Wolfgang Gruneberg / Awais Khan / Marc Ghislain / Daifu Ma / Jiming Jiang / Robert O. M. Mwanga / Jim Leebens-Mack / Lachlan J. M. Coin / G. Craig Yencho / C. Robin Buell / Zhangjun Fei

    Nature Communications, Vol 9, Iss 1, Pp 1-

    2018  Band 12

    Abstract: Sweetpotato is an important food security crop providing rich source of macro- and micronutrients including carbohydrates and vitamins. Here, the authors assemble of the two diploid relatives of cultivated sweetpotato and identify genes and alleles ... ...

    Abstract Sweetpotato is an important food security crop providing rich source of macro- and micronutrients including carbohydrates and vitamins. Here, the authors assemble of the two diploid relatives of cultivated sweetpotato and identify genes and alleles associated with carotenoid biosynthesis from breeding lines.
    Schlagwörter Science ; Q
    Sprache Englisch
    Erscheinungsdatum 2018-11-01T00:00:00Z
    Verlag Nature Portfolio
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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    Kategorien

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