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  1. Artikel ; Online: Usefulness of lung ultrasound in the early identification of severe COVID-19: results from a prospective study.

    Hernández-Píriz, Alba / Tung-Chen, Yale / Jiménez-Virumbrales, David / Ayala-Larrañaga, Ibone / Barba-Martín, Raquel / Canora-Lebrato, Jesús / Zapatero-Gaviria, Antonio / García De Casasola-Sánchez, Gonzalo

    Medical ultrasonography

    2021  Band 24, Heft 2, Seite(n) 146–152

    Abstract: Aim: There is growing evidence regarding the imaging findings of coronavirus disease 2019 (COVID-19) in lung ultrasound (LUS); however, its role in predicting the prognosis has yet to be explored. The aim of the study was to assess the relationship ... ...

    Abstract Aim: There is growing evidence regarding the imaging findings of coronavirus disease 2019 (COVID-19) in lung ultrasound (LUS); however, its role in predicting the prognosis has yet to be explored. The aim of the study was to assess the relationship between lung ultrasound findings with the degree of respiratory failure measured by the PaO2/FiO2 ratio (PaFi) andthe prognosis of these patients: need for non-invasive mechanical ventilation (NIMV), admission to the Intensive Care Unit (ICU) and mortality.
    Material and method: Prospective, longitudinal and observational study performed in patients with confirmed COVID-19 underwent a LUS examination and laboratory tests.
    Results: A total of 107 patients were enrolled: 93.4% with bilateral involvement and 73.83% presented at least one consolidation. A good inverse correlation (Rho Spearman coefficient -0.897) between the ultrasound score and PaFi was obtained. The AUC for identification of patients with more severe respiratory failure, a moderate and severe ARDS, was 0.97 (CI 95%: 0.95-1) and a cut-off score of 34.5 showed a sensitivity of 0.94 and a specificity of 0.91. The Kappa index showed a high concordance (0.83) of the classification by ultrasound lunginvolvement and ARDS.
    Conclusions: The combination of the ultrasound score and the presence of respiratory failure can easily identify patients with a higher risk to present complications.
    Mesh-Begriff(e) COVID-19/diagnostic imaging ; Humans ; Lung/diagnostic imaging ; Prospective Studies ; Respiratory Distress Syndrome/diagnostic imaging ; Respiratory Insufficiency ; Ultrasonography/methods
    Sprache Englisch
    Erscheinungsdatum 2021-11-10
    Erscheinungsland Romania
    Dokumenttyp Journal Article ; Observational Study
    ZDB-ID 2529606-1
    ISSN 2066-8643 ; 1844-4172
    ISSN (online) 2066-8643
    ISSN 1844-4172
    DOI 10.11152/mu-3263
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel: Importance of Lung Ultrasound Follow-Up in Patients Who Had Recovered from Coronavirus Disease 2019: Results from a Prospective Study.

    Hernández-Píriz, Alba / Tung-Chen, Yale / Jiménez-Virumbrales, David / Ayala-Larrañaga, Ibone / Barba-Martín, Raquel / Canora-Lebrato, Jesús / Zapatero-Gaviria, Antonio / Casasola-Sánchez, Gonzalo García De

    Journal of clinical medicine

    2021  Band 10, Heft 14

    Abstract: There is growing evidence regarding the imaging findings of coronavirus disease 2019 (COVID-19) in lung ultrasounds, however, their role in predicting the prognosis has yet to be explored. Our objective was to assess the usefulness of lung ultrasound in ... ...

    Abstract There is growing evidence regarding the imaging findings of coronavirus disease 2019 (COVID-19) in lung ultrasounds, however, their role in predicting the prognosis has yet to be explored. Our objective was to assess the usefulness of lung ultrasound in the short-term follow-up (1 and 3 months) of patients with SARS-CoV-2 pneumonia, and to describe the progression of the most relevant lung ultrasound findings. We conducted a prospective, longitudinal and observational study performed in patients with confirmed COVID-19 who underwent a lung ultrasound examination during hospitalization and repeated it 1 and 3 months after hospital discharge. A total of 96 patients were enrolled. In the initial ultrasound, bilateral involvement was present in 100% of the patients with mild, moderate or severe ARDS. The most affected lung area was the posteroinferior (93.8%) followed by the lateral (88.7%). Subpleural consolidations were present in 68% of the patients and consolidations larger than 1 cm in 24%. One month after the initial study, only 20.8% had complete resolution on lung ultrasound. This percentage rose to 68.7% at 3 months. Residual lesions were observed in a significant percentage of patients who recovered from moderate or severe ARDS (32.4% and 61.5%, respectively). In conclusion, lung injury associated with COVID-19 might take time to resolve. The findings in this report support the use of lung ultrasound in the short-term follow-up of patients recovered from COVID-19, as a radiation-sparing, easy to use, novel care path worth exploring.
    Sprache Englisch
    Erscheinungsdatum 2021-07-20
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm10143196
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Utility of lateral flow tests in SARS-CoV-2 infection monitorization.

    Candel, F J / Viñuela-Prieto, J M / González Del Castillo, J / Barreiro García, P / Fragiel Saavedra, M / Hernández Píriz, A / Jiménez Virumbrales, D / Canora Lebrato, J / García de Casasola, G / Gil Prieto, R / San-Román Montero, J / Ortega Anselmi, J / Barba Martín, R / Prados Roa, F / Marco Martínez, J / Zapatero Gaviria, A

    Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia

    2020  Band 33, Heft 4, Seite(n) 258–266

    Abstract: Objective: The diagnosis of SARS-CoV-2 infection is crucial for medical and public health reasons, to allow the best treatment of cases and the best control of the pandemic. Serology testing allows for the detection of asymptomatic infections and 19- ... ...

    Abstract Objective: The diagnosis of SARS-CoV-2 infection is crucial for medical and public health reasons, to allow the best treatment of cases and the best control of the pandemic. Serology testing allows for the detection of asymptomatic infections and 19-COVID cases once the virus has been cleared. We analyzed the usefulness of the SARS-CoV-2 rapid test of Autobio and tried to correlate its pattern with the severity of COVID19 infection.
    Methods: We analyzed the accuracy and clinical usefulness of a point-of-care IgM and/or IgG test for SARS-CoV-2 in 35 COVID-19 patients [12 (34.3%) mild-moderate and 23 (65.7%) severe-critical] admitted to a field hospital in Madrid, as well as in 5 controls.
    Results: The mean time from the first day of symptoms to the antibody test was 28 days (SD: 8.7), similar according to the severity of the disease. All patients with SARS-CoV-2 PCR+ showed the corresponding IgG positivity, while these results were negative in all control individuals. A total of 26 (74%) cases also presented with positive IgM, 19 (83%) were severe-critical cases and 7 (58%) were mild-moderate cases. The IgM response lasted longer in the severe critical cases (mean: 29.7 days; SD: 8.4) compared to the moderate cases (mean: 21.2 days; SD: 2.0)..
    Conclusions: Rapid serology tests are useful for the diagnosis of patients with COVID-19 (mainly IgG detection) and may also be correlated with the severity of the infection (based on IgM detection).
    Mesh-Begriff(e) Adult ; Aged ; Antibodies, Viral/blood ; Asymptomatic Infections ; Betacoronavirus/immunology ; COVID-19 ; COVID-19 Testing ; Clinical Laboratory Techniques/methods ; Coronavirus Infections/diagnosis ; Coronavirus Infections/virology ; Cross-Sectional Studies ; Female ; Humans ; Immunoassay/methods ; Immunoglobulin G/blood ; Immunoglobulin M/blood ; Male ; Middle Aged ; Pandemics ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/virology ; Point-of-Care Testing ; Reverse Transcriptase Polymerase Chain Reaction ; SARS-CoV-2 ; Sensitivity and Specificity ; Severity of Illness Index ; Symptom Assessment/statistics & numerical data ; Time Factors
    Chemische Substanzen Antibodies, Viral ; Immunoglobulin G ; Immunoglobulin M
    Schlagwörter covid19
    Sprache Englisch
    Erscheinungsdatum 2020-06-04
    Erscheinungsland Spain
    Dokumenttyp Evaluation Study ; Journal Article
    ZDB-ID 1018135-0
    ISSN 1988-9518 ; 0214-3429
    ISSN (online) 1988-9518
    ISSN 0214-3429
    DOI 10.37201/req/052.2020
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel: Utility of lateral flow tests in SARS-CoV-2 infection monitorization

    Candel, F J / Viñuela-Prieto, J M / González Del Castillo, J / Barreiro García, P / Fragiel Saavedra, M / Hernández Píriz, A / Jiménez Virumbrales, D / Canora Lebrato, J / García de Casasola, G / Gil Prieto, R / San-Román Montero, J / Ortega Anselmi, J / Barba Martín, R / Prados Roa, F / Marco Martínez, J / Zapatero Gaviria, A

    Rev Esp Quimioter

    Abstract: OBJECTIVE: The diagnosis of SARS-CoV-2 infection is crucial for medical and public health reasons, to allow the best treatment of cases and the best control of the pandemic. Serology testing allows for the detection of asymptomatic infections and 19- ... ...

    Abstract OBJECTIVE: The diagnosis of SARS-CoV-2 infection is crucial for medical and public health reasons, to allow the best treatment of cases and the best control of the pandemic. Serology testing allows for the detection of asymptomatic infections and 19-COVID cases once the virus has been cleared. We analyzed the usefulness of the SARS-CoV-2 rapid test of Autobio and tried to correlate its pattern with the severity of COVID19 infection. METHODS: We analyzed the accuracy and clinical usefulness of a point-of-care IgM and/or IgG test for SARS-CoV-2 in 35 COVID-19 patients [12 (34.3%) mild-moderate and 23 (65.7%) severe-critical] admitted to a field hospital in Madrid, as well as in 5 controls. RESULTS: The mean time from the first day of symptoms to the antibody test was 28 days (SD: 8.7), similar according to the severity of the disease. All patients with SARS-CoV-2 PCR+ showed the corresponding IgG positivity, while these results were negative in all control individuals. A total of 26 (74%) cases also presented with positive IgM, 19 (83%) were severe-critical cases and 7 (58%) were mild-moderate cases. The IgM response lasted longer in the severe critical cases (mean: 29.7 days; SD: 8.4) compared to the moderate cases (mean: 21.2 days; SD: 2.0).. CONCLUSIONS: Rapid serology tests are useful for the diagnosis of patients with COVID-19 (mainly IgG detection) and may also be correlated with the severity of the infection (based on IgM detection).
    Schlagwörter covid19
    Verlag WHO
    Dokumenttyp Artikel
    Anmerkung WHO #Covidence: #530953
    Datenquelle COVID19

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