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  1. Buch: Weedon's Skin Pathology Essentials

    Johnston, Ronald

    2023  

    Verfasserangabe Dr. Johnston was a Colonel in the US Air Force (F15 Fighter pilot) and was Chief of Dermatology at Eglin Air Force base in Florida. He is now retired from Air Force and has an academic position at the dermatology department at the University of South Florida as well as a private practice "Advanced Dermatology and Skin Care Center) in Tampa
    Sprache Englisch
    Umfang 808 p.
    Ausgabenhinweis 3
    Verlag Elsevier Science
    Dokumenttyp Buch
    Anmerkung PDA Manuell_21
    Format 255 x 317 x 36
    ISBN 9780702084478 ; 0702084476
    Datenquelle PDA

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  2. Artikel ; Online: The first 6 months of HIV-SARS-CoV-2 coinfection: outcomes for 6947 individuals.

    Johnston, Rowena

    Current opinion in HIV and AIDS

    2021  Band 16, Heft 1, Seite(n) 54–62

    Abstract: Purpose of review: The aim of this review is to summarize the clinical outcomes of people living with HIV (PWH) coinfected with SARS-CoV-2 during the first six months of the COVID-19 pandemic.: Recent findings: Several reports from single centers ... ...

    Abstract Purpose of review: The aim of this review is to summarize the clinical outcomes of people living with HIV (PWH) coinfected with SARS-CoV-2 during the first six months of the COVID-19 pandemic.
    Recent findings: Several reports from single centers have described increased, decreased, or no difference in outcomes of COVID-19 in PWH. These studies have come from a range of locations, each with different underlying HIV prevalence and access to various antiretroviral therapy (ART) regimens. Differences in healthcare quality, access and policies may also affect reported outcomes in PWH across different locations, making interpretation of results more challenging. Meanwhile, different components of ART have been proposed to protect against SARS-CoV-2 acquisition or disease progression.
    Summary: The current review considers 6 months of data across geographic regions with a range of healthcare quality and access and ART regimens to generate a wider view of COVID-19 outcomes in PWH. Taken together, these studies indicate that HIV infection may be associated with increased risk of COVID-19 diagnosis, but comorbidities appear to play a larger role than HIV-specific variables in outcomes of COVID-19 among PWH. ART does not appear to protect from COVID-19 disease acquisition, progression or death.
    Mesh-Begriff(e) Animals ; COVID-19/epidemiology ; COVID-19/virology ; Coinfection/epidemiology ; Coinfection/virology ; HIV/genetics ; HIV/physiology ; HIV Infections/epidemiology ; HIV Infections/virology ; Humans ; Pandemics ; SARS-CoV-2/genetics ; SARS-CoV-2/physiology
    Schlagwörter covid19
    Sprache Englisch
    Erscheinungsdatum 2021-01-22
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2502511-9
    ISSN 1746-6318 ; 1746-630X
    ISSN (online) 1746-6318
    ISSN 1746-630X
    DOI 10.1097/COH.0000000000000654
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel: Brain-wide arousal signals are segregated from movement planning in the superior colliculus.

    Johnston, Richard / Smith, Matthew A

    bioRxiv : the preprint server for biology

    2024  

    Abstract: The superior colliculus (SC) is traditionally considered a brain region that functions as an interface between processing visual inputs and generating eye movement outputs. Although its role as a primary reflex center is thought to be conserved across ... ...

    Abstract The superior colliculus (SC) is traditionally considered a brain region that functions as an interface between processing visual inputs and generating eye movement outputs. Although its role as a primary reflex center is thought to be conserved across vertebrate species, evidence suggests that the SC has evolved to support higher-order cognitive functions including spatial attention. When it comes to oculomotor areas such as the SC, it is critical that high precision fixation and eye movements are maintained even in the presence of signals related to ongoing changes in cognition and brain state, both of which have the potential to interfere with eye position encoding and movement generation. In this study, we recorded spiking responses of neuronal populations in the SC while monkeys performed a memory-guided saccade task and found that the activity of some of the neurons fluctuated over tens of minutes. By leveraging the statistical power afforded by high-dimensional neuronal recordings, we were able to identify a low-dimensional pattern of activity that was correlated with the subjects' arousal levels. Importantly, we found that the spiking responses of deep-layer SC neurons were less correlated with this brain-wide arousal signal, and that neural activity associated with changes in pupil size and saccade tuning did not overlap in population activity space with movement initiation signals. Taken together, these findings provide a framework for understanding how signals related to cognition and arousal can be embedded in the population activity of oculomotor structures without compromising the fidelity of the motor output.
    Sprache Englisch
    Erscheinungsdatum 2024-04-29
    Erscheinungsland United States
    Dokumenttyp Preprint
    DOI 10.1101/2024.04.26.591284
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel ; Online: What Might Surviving Coronavirus Disease 2019 Look Like for People Living with HIV?

    Johnston, Rowena

    AIDS patient care and STDs

    2020  Band 35, Heft 1, Seite(n) 1–4

    Sprache Englisch
    Erscheinungsdatum 2020-12-16
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 1326868-5
    ISSN 1557-7449 ; 0893-5068 ; 1087-2914
    ISSN (online) 1557-7449
    ISSN 0893-5068 ; 1087-2914
    DOI 10.1089/apc.2020.29006.com
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: Engaging Cell and Gene Therapists in HIV Cure.

    Johnston, Rowena

    Human gene therapy

    2020  Band 32, Heft 1-2, Seite(n) 17–20

    Abstract: Cell and gene therapy (CGT) has a variety of potential applications in HIV prevention and management. Bibliometric and network analyses suggest potential points of entry for gene therapists into HIV cure research. The existing network of CGT researchers ... ...

    Abstract Cell and gene therapy (CGT) has a variety of potential applications in HIV prevention and management. Bibliometric and network analyses suggest potential points of entry for gene therapists into HIV cure research. The existing network of CGT researchers for HIV cure will benefit from an influx of fresh ideas and energy from CGT researchers keen to embrace a new challenge for an old virus.
    Mesh-Begriff(e) Genetic Therapy ; HIV Infections/genetics ; HIV Infections/therapy ; HIV-1/genetics ; Hematopoietic Stem Cell Transplantation ; Humans ; Research Personnel
    Schlagwörter covid19
    Sprache Englisch
    Erscheinungsdatum 2020-10-15
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 1028152-6
    ISSN 1557-7422 ; 1043-0342
    ISSN (online) 1557-7422
    ISSN 1043-0342
    DOI 10.1089/hum.2020.236
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Buch: Climate change, water and agriculture in the Greater Mekong Subregion

    Johnston, Robyn

    (IWMI research report ; 136)

    2010  

    Verfasserangabe Robyn Johnston
    Serientitel IWMI research report ; 136
    Research report / International Water Management Institute
    Überordnung Research report / International Water Management Institute
    Sprache Englisch
    Umfang VII, 52 S. : graph. Darst., Kt.
    Verlag IWMI
    Erscheinungsort Colombo
    Erscheinungsland Sri Lanka
    Dokumenttyp Buch
    HBZ-ID HT017202749
    ISBN 978-92-9090-728-2 ; 92-9090-728-2
    Datenquelle Katalog ZB MED Ernährung, Umwelt, Agrar

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  7. Artikel ; Online: Water stresses and responses in Myanmar’s Central Dry Zone

    Drury, L. / Johnston, R. / Schmitter, Petra

    2023  

    Abstract: In Ojha, H.; Schofield, N.; Camkin, J. (Eds.). Climate risks to water security: framing effective response in Asia and the Pacific. Cham, Switzerland: Palgrave Macmillan ... The Central Dry Zone (CDZ) of Myanmar is the heartland of the Burmese culture, and ...

    Abstract In Ojha, H.; Schofield, N.; Camkin, J. (Eds.). Climate risks to water security: framing effective response in Asia and the Pacific. Cham, Switzerland: Palgrave Macmillan

    The Central Dry Zone (CDZ) of Myanmar is the heartland of the Burmese culture, and in many ways, it is socially and culturally coherent with the other rice-centred cultures of mainland Southeast Asia. In climatic terms, it is a semi-arid outlier in a mostly wet-tropical region. Climate change is exacerbating weather variability and water insecurity, and the CDZ thus epitomises the challenges posed by climate change for much of the region. This chapter describes two examples of interventions aimed at addressing water insecurity in the CDZ: pumped irrigation at Pyawt Ywar; and artesian groundwater in the Pale Subbasin. Both address the interconnections between social and physical drivers of vulnerability. They demonstrate the challenges and importance of working across institutional scales. These examples demonstrate that progress is possible at local levels despite a lack of (or inappropriate) national policy and regulations, which limit the scale, and possibly the long-term sustainability of such gains.
    Schlagwörter water stress ; arid zones ; water scarcity ; surface water ; surface irrigation ; climate change ; groundwater irrigation ; groundwater management ; tube wells ; aquifers
    Sprache Englisch
    Erscheinungsdatum 2023-01-31T23:31:22Z
    Verlag Springer
    Erscheinungsland fr
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  8. Artikel: Engaging cell and gene therapists in HIV cure

    Johnston, Rowena

    Hum. gene ther

    Abstract: Cell and gene therapy (CGT) has a variety of potential applications in human immunodeficiency virus (HIV) prevention and management. The existing network of CGT researchers for HIV cure will benefit from an influx of fresh ideas and energy from CGT ... ...

    Abstract Cell and gene therapy (CGT) has a variety of potential applications in human immunodeficiency virus (HIV) prevention and management. The existing network of CGT researchers for HIV cure will benefit from an influx of fresh ideas and energy from CGT researchers keen to embrace a new challenge for an old virus.
    Schlagwörter covid19
    Verlag WHO
    Dokumenttyp Artikel
    Anmerkung WHO #Covidence: #32962421
    Datenquelle COVID19

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  9. Artikel: The first 6 months of HIV-SARS-CoV-2 coinfection: outcomes for 6947 individuals

    Johnston, Rowena

    Curr. opin. HIV AIDS

    Abstract: PURPOSE OF REVIEW: The aim of this review is to summarize the clinical outcomes of people living with HIV (PWH) coinfected with SARS-CoV-2 during the first six months of the COVID-19 pandemic. RECENT FINDINGS: Several reports from single centers have ... ...

    Abstract PURPOSE OF REVIEW: The aim of this review is to summarize the clinical outcomes of people living with HIV (PWH) coinfected with SARS-CoV-2 during the first six months of the COVID-19 pandemic. RECENT FINDINGS: Several reports from single centers have described increased, decreased, or no difference in outcomes of COVID-19 in PWH. These studies have come from a range of locations, each with different underlying HIV prevalence and access to various antiretroviral therapy (ART) regimens. Differences in healthcare quality, access and policies may also affect reported outcomes in PWH across different locations, making interpretation of results more challenging. Meanwhile, different components of ART have been proposed to protect against SARS-CoV-2 acquisition or disease progression. SUMMARY: The current review considers 6 months of data across geographic regions with a range of healthcare quality and access and ART regimens to generate a wider view of COVID-19 outcomes in PWH. Taken together, these studies indicate that HIV infection may be associated with increased risk of COVID-19 diagnosis, but comorbidities appear to play a larger role than HIV-specific variables in outcomes of COVID-19 among PWH. ART does not appear to protect from COVID-19 disease acquisition, progression or death.
    Schlagwörter covid19
    Verlag WHO
    Dokumenttyp Artikel
    Anmerkung WHO #Covidence: #915919
    Datenquelle COVID19

    Kategorien

  10. Artikel ; Online: The first 6 months of HIV-SARS-CoV-2 coinfection ; outcomes for 6947 individuals

    Johnston, Rowena

    Current Opinion in HIV and AIDS

    2020  Band Publish Ahead of Print

    Schlagwörter Immunology ; Oncology(nursing) ; Oncology ; Virology ; Infectious Diseases ; Hematology ; covid19
    Sprache Englisch
    Verlag Ovid Technologies (Wolters Kluwer Health)
    Erscheinungsland us
    Dokumenttyp Artikel ; Online
    ZDB-ID 2502511-9
    ISSN 1746-630X
    ISSN 1746-630X
    DOI 10.1097/coh.0000000000000654
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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