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  1. Artikel ; Online: Telehealth use and perceptions among prostate cancer survivors.

    Chen, Luke W / Usinger, Deborah S / Katz, Aaron J

    Cancer medicine

    2023  Band 12, Heft 16, Seite(n) 17308–17312

    Abstract: Background: Reasons underlying disparities in telehealth use among cancer survivors are unknown.: Methods: We surveyed a sociodemographically diverse population-based cohort of 487 prostate cancer survivors regarding their use and perceptions of ... ...

    Abstract Background: Reasons underlying disparities in telehealth use among cancer survivors are unknown.
    Methods: We surveyed a sociodemographically diverse population-based cohort of 487 prostate cancer survivors regarding their use and perceptions of telehealth during the COVID-19 pandemic.
    Results: Overall, only 28.5% of survivors had used telehealth at the time of survey and just 10% felt care through telehealth is comparable to that of an in-person visit. Still, over 55% felt telehealth is a good option for initial consultations or basic care and 15% felt more likely to use telehealth since the pandemic. After adjusting for other socioeconomic factors, survivors with lower education (≤high school vs. any college) had marginally lower use of telehealth (risk ratio [RR], 0.65 [95% CI, 0.42-1.01]) and lower probability of feeling more likely to use telehealth since the pandemic (RR, 0.39 [95% CI, 0.20-0.77]).
    Conclusions: Differences in survivor perceptions of telehealth by education level highlight new insights underlying disparities in telehealth use and potential targets for interventions.
    Mesh-Begriff(e) Male ; Humans ; Prostate ; Cancer Survivors ; Pandemics ; COVID-19/epidemiology ; Prostatic Neoplasms/epidemiology ; Prostatic Neoplasms/therapy ; Survivors ; Telemedicine
    Sprache Englisch
    Erscheinungsdatum 2023-07-16
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, U.S. Gov't, Non-P.H.S. ; Research Support, U.S. Gov't, P.H.S.
    ZDB-ID 2659751-2
    ISSN 2045-7634 ; 2045-7634
    ISSN (online) 2045-7634
    ISSN 2045-7634
    DOI 10.1002/cam4.6328
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: A targeted fluorescent nanosensor for ratiometric pH sensing at the cell surface.

    Kromer, Charlotte / Katz, Aaron / Feldmann, Ines / Laux, Peter / Luch, Andreas / Tschiche, Harald R

    Scientific reports

    2024  Band 14, Heft 1, Seite(n) 12302

    Abstract: The correlation between altered extracellular pH and various pathological conditions, including cancer, inflammation and metabolic disorders, is well known. Bulk pH measurements cannot report the extracellular pH value at the cell surface. However, there ...

    Abstract The correlation between altered extracellular pH and various pathological conditions, including cancer, inflammation and metabolic disorders, is well known. Bulk pH measurements cannot report the extracellular pH value at the cell surface. However, there is a limited number of suitable tools for measuring the extracellular pH of cells with high spatial resolution, and none of them are commonly used in laboratories around the world. In this study, a versatile ratiometric nanosensor for the measurement of extracellular pH was developed. The nanosensor consists of biocompatible polystyrene nanoparticles loaded with the pH-inert reference dye Nile red and is surface functionalized with a pH-responsive fluorescein dye. Equipped with a targeting moiety, the nanosensor can adhere to cell membranes, allowing direct measurement of extracellular pH at the cell surface. The nanosensor exhibits a sensitive ratiometric pH response within the range of 5.5-9.0, with a calculated pKa of 7.47. This range optimally covers the extracellular pH (pH
    Mesh-Begriff(e) Hydrogen-Ion Concentration ; Humans ; Fluorescent Dyes/chemistry ; Nanoparticles/chemistry ; Cell Membrane/metabolism ; Biosensing Techniques/methods ; Biosensing Techniques/instrumentation ; Oxazines/chemistry ; Polystyrenes/chemistry
    Chemische Substanzen Fluorescent Dyes ; Oxazines ; nile red (P476F1L81G) ; Polystyrenes
    Sprache Englisch
    Erscheinungsdatum 2024-05-29
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-62976-2
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Differences in Rural Versus Urban Patients With Prostate Cancer in Diagnosis and Treatment: An Analysis of a Population-Based Cohort.

    Shen, Xinglei / Kane, Katelyn / Katz, Aaron J / Usinger, Deborah / Cao, Ying / Chen, Ronald C

    JCO oncology practice

    2024  , Seite(n) OP2300547

    Abstract: Purpose: Patients living in rural communities have greater barriers to cancer care and poorer outcomes. We hypothesized that rural patients with prostate cancer have less access and receive different treatments compared with urban patients.: Methods: ...

    Abstract Purpose: Patients living in rural communities have greater barriers to cancer care and poorer outcomes. We hypothesized that rural patients with prostate cancer have less access and receive different treatments compared with urban patients.
    Methods: We used a population-based prospective cohort, the North Carolina Prostate Cancer Comparative Effectiveness and Survivorship Study, to compare differences in prostate cancer diagnosis, access to care, and treatment in patients by geographic residence. The 2013 rural-urban continuum code (RUCC) was used to determine urban (RUCC 1-3) versus rural (RUCC 4-9) location of residence.
    Results: Patients with rural residence comprised 25% of the cohort (364 of 1,444); they were less likely to be White race and had lower income and educational attainment. Rural patients were more likely to have <12 cores on biopsy (47.1%
    Conclusion: Patients with prostate cancer who live in rural versus urban areas experience several differences in care that are likely clinically meaningful, including fewer cores in the diagnostic biopsy, less utilization of multidisciplinary consultation, less use of active surveillance, or observation for low-risk disease. Future studies are needed to assess the efficacy of interventions in mitigating these disparities.
    Sprache Englisch
    Erscheinungsdatum 2024-05-13
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 3028198-2
    ISSN 2688-1535 ; 2688-1527
    ISSN (online) 2688-1535
    ISSN 2688-1527
    DOI 10.1200/OP.23.00547
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel ; Online: A framework policy analysis of national health insurance policymaking in sub-Saharan Africa.

    Roll, Amy / Katz, Aaron / Lane, Jeff

    Health policy and planning

    2021  Band 36, Heft 8, Seite(n) 1246–1256

    Abstract: National health insurance (NHI) is a financing mechanism established by a national government with the goal of covering all or almost all of its citizens. A number of low- and middle-income countries have established NHIs as part of a strategy to ... ...

    Abstract National health insurance (NHI) is a financing mechanism established by a national government with the goal of covering all or almost all of its citizens. A number of low- and middle-income countries have established NHIs as part of a strategy to progress towards universal health coverage. The establishment of an NHI presents a potentially significant shift in national health sector governance, but little is available in the literature regarding how policymaking authority and health governance is shared between NHIs and ministries of health (MOHs). To answer this question, we conducted a descriptive, qualitative comparative analysis of policies, including legislation, guidelines and webpages, from four sub-Saharan African countries that have established or are in the process of establishing an NHI scheme as of 2019 (Ghana, Kenya, Zambia and South Africa). We developed a novel conceptual framework comprising 16 NHI policy domains and conducted a deductive review of relevant policies. We then extracted and indexed policy elements according to this framework to facilitate comparative analysis. We found substantial variation across countries in the types of policies developed and the decision-making authority around those policies. MOHs in all four countries retained at least some decision-making power over the NHIs through regulations and appointment of board members. However, NHIs were often delegated policymaking authority in key areas including financing mechanisms, provider payments, member payments, benefit schemes, accreditation and relationships with private health insurance schemes. The results of this analysis illustrate many aspects of health regulatory power and oversight that will need to be defined as part of establishing NHIs. The approaches from these four countries and the conceptual framework presented in this manuscript may be helpful for other countries in evaluating differing approaches to shared health governance between NHIs and MOHs.
    Mesh-Begriff(e) Health Policy ; Humans ; Insurance, Health ; Kenya ; National Health Programs ; Policy Making ; Universal Health Insurance
    Sprache Englisch
    Erscheinungsdatum 2021-04-09
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 632896-9
    ISSN 1460-2237 ; 0268-1080
    ISSN (online) 1460-2237
    ISSN 0268-1080
    DOI 10.1093/heapol/czaa160
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: Evaluation of a New Cystoscopic Cryocatheter and Method for the

    Baust, John M / Corcoran, Anthony / Robilotto, Anthony / Katz, Aaron / Santucci, Kimberly / Van Buskirk, Robert G / Baust, John G / Snyder, Kristi K

    Journal of endourology

    2024  Band 38, Heft 5, Seite(n) 513–520

    Abstract: Purpose: ...

    Abstract Purpose:
    Mesh-Begriff(e) Animals ; Cryosurgery/methods ; Urinary Bladder Neoplasms/surgery ; Urinary Bladder Neoplasms/pathology ; Urinary Bladder Neoplasms/diagnostic imaging ; Cystoscopy/methods ; Urinary Bladder/surgery ; Urinary Bladder/pathology ; Sus scrofa ; Preliminary Data ; Swine
    Sprache Englisch
    Erscheinungsdatum 2024-02-26
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Evaluation Study
    ZDB-ID 356931-7
    ISSN 1557-900X ; 0892-7790
    ISSN (online) 1557-900X
    ISSN 0892-7790
    DOI 10.1089/end.2023.0635
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel ; Online: Reply.

    Werneburg, Glenn T / Katz, Aaron E

    Urology

    2018  Band 113, Seite(n) 117–118

    Sprache Englisch
    Erscheinungsdatum 2018-02-01
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Comment
    ZDB-ID 192062-5
    ISSN 1527-9995 ; 0090-4295
    ISSN (online) 1527-9995
    ISSN 0090-4295
    DOI 10.1016/j.urology.2017.10.056
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel ; Online: A need for open public data standards and sharing in light of COVID-19.

    Gardner, Lauren / Ratcliff, Jeremy / Dong, Ensheng / Katz, Aaron

    The Lancet. Infectious diseases

    2020  Band 21, Heft 4, Seite(n) e80

    Mesh-Begriff(e) Administrative Personnel ; COVID-19/epidemiology ; Consumer Health Information/standards ; Humans ; Information Dissemination ; Pandemics ; Public Health ; Reference Standards ; SARS-CoV-2/isolation & purification
    Schlagwörter covid19
    Sprache Englisch
    Erscheinungsdatum 2020-08-10
    Erscheinungsland United States
    Dokumenttyp Letter
    ZDB-ID 2061641-7
    ISSN 1474-4457 ; 1473-3099
    ISSN (online) 1474-4457
    ISSN 1473-3099
    DOI 10.1016/S1473-3099(20)30635-6
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel ; Online: Evaluation of Telemedicine Use Among US Patients With Newly Diagnosed Cancer by Socioeconomic Status.

    Katz, Aaron J / Haynes, Kevin / Du, Simo / Barron, John / Kubik, Rhyan / Chen, Ronald C

    JAMA oncology

    2022  Band 8, Heft 1, Seite(n) 161–163

    Mesh-Begriff(e) Humans ; Neoplasms/diagnosis ; Neoplasms/epidemiology ; Neoplasms/therapy ; Social Class ; Telemedicine
    Sprache Englisch
    Erscheinungsdatum 2022-01-20
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ISSN 2374-2445
    ISSN (online) 2374-2445
    DOI 10.1001/jamaoncol.2021.5784
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel ; Online: Antipsychotic Use in Early Pregnancy and the Risk of Maternal and Neonatal Complications.

    Lin, Hsuan-Yu / Lin, Fang-Ju / Katz, Aaron J / Wang, I-Te / Wu, Chung-Hsuen

    Mayo Clinic proceedings

    2022  Band 97, Heft 11, Seite(n) 2086–2096

    Abstract: Objective: To assess the association between antipsychotic use in early pregnancy and the risk of maternal and neonatal metabolic complications.: Methods: We conducted a population-based retrospective cohort study (January 1, 2010, to December 31, ... ...

    Abstract Objective: To assess the association between antipsychotic use in early pregnancy and the risk of maternal and neonatal metabolic complications.
    Methods: We conducted a population-based retrospective cohort study (January 1, 2010, to December 31, 2016) using the Health and Welfare Database in Taiwan. Pregnant women (18 to 49 years of age) were grouped as antipsychotic users (ie, received oral antipsychotic monotherapy during the first 20 weeks of pregnancy) and nonusers. Antipsychotic users were further categorized into first-generation antipsychotic and second-generation antipsychotic users. Propensity score methods, including matching and inverse probability of treatment weighting, were used to balance covariates. Conditional logistic regression and Cox proportional hazards models were used to compare risks of maternal (gestational diabetes mellitus, preterm birth) and neonatal (low birth weight [LBW], macrosomia) outcomes.
    Results: Antipsychotic users had a notably higher risk of preterm birth compared with nonusers (adjusted HR, 1.29; 95% CI, 1.04 to 1.60), but the risk of gestational diabetes mellitus (HR, 1.21; 95% CI, 0.94 to 1.56), LBW (odds ratio [OR], 1.07; 95% CI, 0.84 to 1.37), and macrosomia (OR, 1.36; 95% CI, 0.63 to 2.92) did not differ between the two groups. Among women who received antipsychotics, the odds of LBW were significantly higher in second-generation antipsychotic users compared with first-generation antipsychotic users (adjusted OR, 1.32; 95% CI, 1.04 to 1.68).
    Conclusion: This study found that using antipsychotics in early pregnancy did not result in a greater risk of metabolic complications both for mothers and newborns. For women requiring treatment with antipsychotics during pregnancy, they should be monitored for the risk of preterm birth and low infant birth weight.
    Mesh-Begriff(e) Infant, Newborn ; Female ; Pregnancy ; Humans ; Infant ; Premature Birth/chemically induced ; Premature Birth/epidemiology ; Antipsychotic Agents/adverse effects ; Fetal Macrosomia/chemically induced ; Fetal Macrosomia/epidemiology ; Diabetes, Gestational/chemically induced ; Diabetes, Gestational/drug therapy ; Diabetes, Gestational/epidemiology ; Retrospective Studies ; Pregnancy Complications/drug therapy ; Pregnancy Complications/epidemiology ; Pregnancy Outcome/epidemiology
    Chemische Substanzen Antipsychotic Agents
    Sprache Englisch
    Erscheinungsdatum 2022-10-07
    Erscheinungsland England
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 124027-4
    ISSN 1942-5546 ; 0025-6196
    ISSN (online) 1942-5546
    ISSN 0025-6196
    DOI 10.1016/j.mayocp.2022.04.006
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  10. Artikel ; Online: Effect of Prostate Volume and Minimum Tumor Temperature on 4-Year Quality-of-Life After Focal Cryoablation Compared with Active Surveillance in Men with Prostate Cancer.

    Monaco, Ashley / Sommer, Jessica / Akerman, Meredith / Joshi, Parth / Corcoran, Anthony / Katz, Aaron

    Journal of endourology

    2022  Band 36, Heft 12, Seite(n) 1625–1631

    Abstract: Background: ...

    Abstract Background:
    Mesh-Begriff(e) Humans ; Male ; Quality of Life ; Prostate/surgery ; Watchful Waiting ; Prostatic Neoplasms/surgery
    Sprache Englisch
    Erscheinungsdatum 2022-10-07
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 356931-7
    ISSN 1557-900X ; 0892-7790
    ISSN (online) 1557-900X
    ISSN 0892-7790
    DOI 10.1089/end.2022.0068
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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