LIVIVO - Das Suchportal für Lebenswissenschaften

switch to English language
Erweiterte Suche

Suchergebnis

Treffer 1 - 10 von insgesamt 266

Suchoptionen

  1. Buch: Dermatopathologie

    Kempf, Werner Bernhard

    2015  

    Verfasserangabe Werner Kempf
    Schlagwörter Skin Diseases / pathology ; Diagnosis, Differential ; Histopathologie bei Hautveränderungen ; Dermatologische Pathologie ; Histopathologie der Haut ; Dermatohistopathologie ; Dermatologische Histologie ; Hautkrankheit ; Histopathologie
    Schlagwörter Gewebepathologie ; Histologische Diagnose ; Histologische Pathologie ; Pathohistologie ; Pathologische Histologie ; Dermatose ; Haut ; Hauterkrankung ; Hautkrankheiten
    Sprache Deutsch
    Umfang XI, 328 S. : zahlr. Ill.
    Ausgabenhinweis 3. Aufl.
    Verlag Springer
    Erscheinungsort Berlin u.a.
    Erscheinungsland Deutschland
    Dokumenttyp Buch
    HBZ-ID HT018669023
    ISBN 978-3-662-46407-6 ; 3-662-46407-1 ; 9783662464083 ; 366246408X
    Datenquelle Katalog ZB MED Medizin, Gesundheit

    Zusatzmaterialien

    Kategorien

  2. Buch: Dermatopathologie

    Kempf, Werner

    2011  

    Verfasserangabe Werner Kempf
    Schlagwörter Skin Diseases / pathology ; Diagnosis, Differential ; Hautkrankheit ; Histopathologie
    Schlagwörter Gewebepathologie ; Histologische Diagnose ; Histologische Pathologie ; Pathohistologie ; Pathologische Histologie ; Dermatose ; Haut ; Hauterkrankung ; Hautkrankheiten
    Sprache Deutsch
    Umfang XI, 304 S. : zahlr. Ill.
    Ausgabenhinweis 2., erg. Aufl.
    Verlag Springer
    Erscheinungsort Berlin u.a.
    Erscheinungsland Deutschland
    Dokumenttyp Buch
    Anmerkung 1. Aufl. erschienen im Steinkopff-Verl., Darmstadt
    HBZ-ID HT016454173
    ISBN 978-3-642-12895-0 ; 3-642-12895-5
    Datenquelle Katalog ZB MED Medizin, Gesundheit

    Zusatzmaterialien

    Kategorien

  3. Buch ; Online ; E-Book: Atlas of clinical dermatopathology

    Burg, Günter / Kutzner, Heinz / Kempf, Werner / Feit, Josef / Sangueza, Omar

    infectious and parasitic dermatoses

    2021  

    Verfasserangabe editor-in-chief Günter Burg ; associate editors Heinz Kutzner, Werner Kempf, Josef Feit, Omar Sangueza
    Schlagwörter Electronic books
    Sprache Englisch
    Umfang 1 Online-Ressource (xiii, 194 Seiten), Illustrationen, Diagramme
    Verlag Wiley Blackwell
    Erscheinungsort Hoboken, NJ
    Erscheinungsland Vereinigte Staaten
    Dokumenttyp Buch ; Online ; E-Book
    Bemerkung Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT020931288
    ISBN 978-1-119-64708-9 ; 978-1-119-64705-8 ; 9781119647065 ; 1-119-64708-8 ; 1-119-64705-3 ; 1119647061
    Datenquelle ZB MED Katalog Medizin, Gesundheit, Ernährung, Umwelt, Agrar

    Kategorien

  4. Buch: Dermatopathologie

    Kempf, Werner

    2007  

    Verfasserangabe W. Kempf
    Schlagwörter Hautkrankheit ; Histopathologie
    Schlagwörter Gewebepathologie ; Histologische Diagnose ; Histologische Pathologie ; Pathohistologie ; Pathologische Histologie ; Dermatose ; Haut ; Hauterkrankung ; Hautkrankheiten
    Sprache Deutsch
    Umfang XII, 294 S. : zahlr. Ill.
    Verlag Steinkopff
    Erscheinungsort Darmstadt
    Erscheinungsland Deutschland
    Dokumenttyp Buch
    Anmerkung 2. Aufl. erschienen im Springer-Verl., Berlin
    HBZ-ID HT014899423
    ISBN 978-3-7985-1647-2 ; 3-7985-1647-2
    Datenquelle Katalog ZB MED Medizin, Gesundheit

    Zusatzmaterialien

    Kategorien

  5. Buch ; Online ; E-Book: Dermatopathologie

    Kempf, Werner / Hantschke, Markus / Kutzner, Heinz

    2020  

    Verfasserangabe Werner Kempf, Markus Hantschke, Heinz Kutzner
    Schlagwörter Dermatology ; Pathology ; Oncology
    Thema/Rubrik (Code) 616.5
    Sprache Deutsch
    Umfang 1 Online-Ressource (XI, 349 Seiten)
    Ausgabenhinweis 4. Auflage
    Verlag Springer
    Erscheinungsort Berlin
    Erscheinungsland Deutschland
    Dokumenttyp Buch ; Online ; E-Book
    Bemerkung Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT020394580
    ISBN 978-3-662-59240-3 ; 9783662592397 ; 3-662-59240-1 ; 3662592398
    DOI 10.1007/978-3-662-59240-3
    Datenquelle ZB MED Katalog Medizin, Gesundheit, Ernährung, Umwelt, Agrar

    Kategorien

  6. Artikel ; Online: Follicular T helper cells and cutaneous T-cell lymphomas.

    Kempf, Werner

    The British journal of dermatology

    2022  Band 187, Heft 6, Seite(n) 841–842

    Mesh-Begriff(e) Humans ; Lymphoma, T-Cell, Cutaneous/pathology ; T-Lymphocytes, Helper-Inducer/pathology ; Skin Neoplasms/pathology ; Lymphoma, Follicular/pathology
    Sprache Englisch
    Erscheinungsdatum 2022-08-31
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 80076-4
    ISSN 1365-2133 ; 0007-0963
    ISSN (online) 1365-2133
    ISSN 0007-0963
    DOI 10.1111/bjd.21839
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  7. Artikel: A new era for cutaneous CD30-positive T-cell lymphoproliferative disorders.

    Kempf, Werner

    Seminars in diagnostic pathology

    2017  Band 34, Heft 1, Seite(n) 22–35

    Abstract: Cutaneous CD30+ T-cell lymphoproliferative disorders (CD30+ T-LPD) represent a spectrum encompassing lymphomatoid papulosis (LyP), primary cutaneous anaplastic large-cell lymphoma (pcALCL) and borderline lesions. They share the expression of CD30 as a ... ...

    Abstract Cutaneous CD30+ T-cell lymphoproliferative disorders (CD30+ T-LPD) represent a spectrum encompassing lymphomatoid papulosis (LyP), primary cutaneous anaplastic large-cell lymphoma (pcALCL) and borderline lesions. They share the expression of CD30 as a common phenotypic marker. They differ however in their clinical presentation, the histological features and clinical course. Moreover, LyP and PcALCL show numerous clinical, histological and phenotypic variants. Overlapping features of LyP and pcALCL with themselves and with other cutaneous and systemic lymphomas emphasize the importance of careful clinicopathologic correlation and staging in the diagnosis of CD30+ T-LPD. Furthermore, an increasing number of inflammatory and infectious skin disorders harboring medium-sized to large CD30+ cells have to be considered in the differential diagnosis. Whereas the expression of CD30 in cutaneous CD30+ T-LPD stands for a favourable prognosis, its expression in other cutaneous and systemic lymphomas has a divergent impact. The assessment of CD30 expression does not only provide prognostic information, but is of potential therapeutic relevance as CD30 can serve as a therapeutic target. This review focuses on the clinicopathological and phenotypic spectrum of CD30+ T-LPD, its differential diagnoses and the role of CD30 as a diagnostic, prognostic and therapeutic marker.
    Mesh-Begriff(e) Humans ; Ki-1 Antigen/metabolism ; Lymphoma, T-Cell/diagnosis ; Lymphoma, T-Cell/pathology ; Lymphoma, T-Cell/therapy ; Lymphomatoid Papulosis/diagnosis ; Lymphomatoid Papulosis/pathology ; Lymphomatoid Papulosis/therapy ; Skin Neoplasms/diagnosis ; Skin Neoplasms/pathology ; Skin Neoplasms/therapy
    Chemische Substanzen Ki-1 Antigen
    Sprache Englisch
    Erscheinungsdatum 2017-01
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Review
    ZDB-ID 605834-6
    ISSN 1930-1111 ; 0740-2570
    ISSN (online) 1930-1111
    ISSN 0740-2570
    DOI 10.1053/j.semdp.2016.11.005
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  8. Artikel ; Online: Cutaneous T-cell lymphomas-An update 2021.

    Kempf, Werner / Mitteldorf, Christina

    Hematological oncology

    2021  Band 39 Suppl 1, Seite(n) 46–51

    Abstract: Cutaneous T-cell lymphomas (CTCL) represent the majority of primary cutaneous lymphomas (CL). Mycosis fungoides (MF) and cutaneous CD30+ lymphoproliferative disorders account for 80% of all CTCL. CTCL show overlapping histological features. Thus clinical- ...

    Abstract Cutaneous T-cell lymphomas (CTCL) represent the majority of primary cutaneous lymphomas (CL). Mycosis fungoides (MF) and cutaneous CD30+ lymphoproliferative disorders account for 80% of all CTCL. CTCL show overlapping histological features. Thus clinical-pathological correlation is of importance to achieve final diagnosis. MF shows a characteristic evolution with patches, plaques, and in a subset of patients (10%-20%) with tumors. Therapy is stage-adapted with skin-directed therapies such as UV-light therapies and corticosteroids in early disease stage (i.e., patch and limited plaque stage) and systemic therapies (retinoids, interferon, mono chemotherapy, targeted therapy) and/or radiation therapy (local or total skin beam electron) in advanced stages. Novel therapies include targeted therapy such as mogamulizumab (anti-CCR4) or brentuximab vedotin (anti-CD30) and histone deacetylase inhibitors. Considering the impact of targeted therapies, biomarkers such as CD30 are not only crucial for the diagnosis and correct classification of an individual lymphoma case, but also for therapy as they may represent therapeutic targets. In the recently revised WHO classification 2017 and the updated WHO-EORTC classification for CL 2018, primary cutaneous CD8+ acral T-cell lymphoma has been introduced as a new still provisional entity. It displays characteristic clinical, histological, and phenotypic features and exhibits an excellent prognosis. Rare, but aggressive CTCL include cutaneous primary cutaneous aggressive epidermotropic CD8-positive T-cell lymphoma and cutaneous gamma/delta T-cell lymphoma, which present with rapid onset of necrotic or ulcerated plaques and tumors. As they have a poor prognosis, treatment includes multiagent chemotherapy and hematopoietic stem cell transplantation.
    Mesh-Begriff(e) Humans ; Mycosis Fungoides/diagnosis ; Mycosis Fungoides/immunology ; Mycosis Fungoides/pathology ; Mycosis Fungoides/therapy ; Skin Neoplasms/diagnosis ; Skin Neoplasms/immunology ; Skin Neoplasms/pathology ; Skin Neoplasms/therapy
    Sprache Englisch
    Erscheinungsdatum 2021-06-08
    Erscheinungsland England
    Dokumenttyp Journal Article ; Review
    ZDB-ID 604884-5
    ISSN 1099-1069 ; 0278-0232
    ISSN (online) 1099-1069
    ISSN 0278-0232
    DOI 10.1002/hon.2850
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  9. Artikel: Cutaneous Reactions after COVID-19 Vaccines: Analysis of the Clinical and Histopathological Spectrum-Case Series and Review of the Literature.

    Schmid, Ursina / Galambos, Jörg / Pfaltz, Katrin / Hegyi, Ivan / Courvoisier, Salomé / Kempf, Werner

    Dermatopathology (Basel, Switzerland)

    2024  Band 11, Heft 1, Seite(n) 130–141

    Abstract: 1) Background: Various cutaneous adverse drug reactions (ADRs) are observed with the implementation of mRNA COVID-19 vaccines. To gain insight into the clinicopathologic features, we analyzed the correlation of histological and clinical data in 48 ... ...

    Abstract (1) Background: Various cutaneous adverse drug reactions (ADRs) are observed with the implementation of mRNA COVID-19 vaccines. To gain insight into the clinicopathologic features, we analyzed the correlation of histological and clinical data in 48 patients with these ADRs. (2) Methods: Single-center retrospective study in patients with ADRs after mRNA COVID-19 vaccination (mRNA-1273 and BNT162b2 vaccines). (3) Results: Distant generalized ADRs prevailed (91%), often appearing clinically as spongiotic dermatitis or maculopapular exanthema. Histopathological analysis revealed spongiotic changes (46%) and dermal superficial perivascular predominantly lymphocytic infiltrates (17%). Eosinophils were found in 66% of biopsies, neutrophils in 29%, and plasma cells only in 8% of biopsies. Most ADRs occurred after the second vaccine dose (44%). Histologically spongiotic changes were associated with clinical features of spongiotic dermatitis in only 50% of patients and maculopapular exanthema in the remaining patients. ADRs represented an aggravation of preexisting skin disease in 23% of patients. ADRs regressed within 28 days or less in 53% of patients and persisted beyond a month in the remaining patients. (4) Conclusions: Our study demonstrates a diverse spectrum of generalized ADRs, revealing correlations between histology and clinical features but also instances of divergence. Interestingly, in about half of our patients, ADRs were self-limited, whereas ADRs extended beyond a month in the other half.
    Sprache Englisch
    Erscheinungsdatum 2024-03-14
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2777118-0
    ISSN 2296-3529
    ISSN 2296-3529
    DOI 10.3390/dermatopathology11010013
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  10. Buch ; Online: Cutaneous Lymphomas Unusual Cases 2

    Michaelis, S. / Burg, Günter / Feit, J. / Kempf, Werner

    2006  

    Verfasserangabe edited by S. Michaelis, J. Feit, Günter Burg, Werner Kempf
    Schlagwörter Dermatology ; Pathology
    Sprache Englisch
    Verlag Steinkopff Verlag Darmstadt
    Erscheinungsort Darmstadt
    Dokumenttyp Buch ; Online
    HBZ-ID TT050387851
    ISBN 978-3-7985-1609-0 ; 978-3-7985-1610-6 ; 3-7985-1609-X ; 3-7985-1610-3
    DOI 10.1007/3-7985-1610-3
    Datenquelle ZB MED Katalog Medizin, Gesundheit, Ernährung, Umwelt, Agrar

    Kategorien

Zum Seitenanfang