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  1. Artikel ; Online: Transforming the Stability, Encapsulation, and Sustained Release Properties of Calcium Alginate Beads through Gel-Confined Coacervation.

    Egbeyemi, Oluwadamilola I / Hatem, Wesam A / Kober, Umberto A / Lapitsky, Yakov

    Langmuir : the ACS journal of surfaces and colloids

    2024  

    Abstract: Calcium alginate ( ... ...

    Abstract Calcium alginate (Ca
    Sprache Englisch
    Erscheinungsdatum 2024-05-28
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 2005937-1
    ISSN 1520-5827 ; 0743-7463
    ISSN (online) 1520-5827
    ISSN 0743-7463
    DOI 10.1021/acs.langmuir.4c00297
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel: Equilibration of precipitants in a counter-diffusion apparatus for protein crystallization.

    Kober, Umberto A / Ogbuoji, Ebuka A / Hutchinson, John A / Mueser, Timothy C / Schall, Constance A

    Journal of applied crystallography

    2023  Band 56, Heft Pt 4, Seite(n) 1057–1065

    Abstract: A cost-effective capillary dialysis apparatus (Toledo Capillary Box, TCB) developed for biomacromolecule crystal growth in microgravity and unit gravity environments can provide slow equilibration between the precipitant reservoir and capillary solutions, ...

    Abstract A cost-effective capillary dialysis apparatus (Toledo Capillary Box, TCB) developed for biomacromolecule crystal growth in microgravity and unit gravity environments can provide slow equilibration between the precipitant reservoir and capillary solutions, nurturing growth of neutron-diffraction-quality crystals. Under microgravity conditions, mass transfer of precipitants and biomacro-mol-ecules occurs under diffusion-controlled conditions, promoting slow growth and suppressing defect formation. The equilibration of common precipitants (polyethyl-ene glycol and salts such as ammonium sulfate) between capillary and reservoir solutions was measured for capillaries oriented horizontally or vertically with respect to the gravitational field at unit gravity. Precipitants equilibrated less rapidly in the vertical orientation when capillary solution densities were lower than those of the reservoir solutions. A plug filled with agarose gel was introduced in the TCB apparatus for salt precipitants since salts often exhibit relatively high free diffusion. Equilibration of the capillaries with reservoir solutions was significantly delayed for many of the salt precipitants tested. Analytical and semi-analytical models allow the prediction of precipitant equilibration of capillary and reservoir solutions under diffusion-controlled transport and show good agreement with experimental results.
    Sprache Englisch
    Erscheinungsdatum 2023-06-23
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 2020879-0
    ISSN 1600-5767 ; 0021-8898
    ISSN (online) 1600-5767
    ISSN 0021-8898
    DOI 10.1107/S1600576723004958
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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