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Artikel ; Online: Author's reply: To PMID 23148932.

Lee, I S / Yook, J H

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

2013 Band 39, Heft 7, Seite(n) 805

Mesh-Begriff(e)	Female ; Gastrectomy ; Humans ; Lymph Node Excision ; Male ; Neoplasm Recurrence, Local/epidemiology ; Peritoneal Neoplasms/epidemiology ; Stomach Neoplasms/epidemiology ; Stomach Neoplasms/surgery
Sprache	Englisch
Erscheinungsdatum	2013-07
Erscheinungsland	England
Dokumenttyp	Comment ; Letter
ZDB-ID	632519-1
ISSN	1532-2157 ; 0748-7983
ISSN (online)	1532-2157
ISSN	0748-7983
DOI	10.1016/j.ejso.2013.03.018
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel: Effect of weight bearing exercise to improve bone mineral density in children with cerebral palsy: a meta-analysis.

Kim, S J / Kim, S-N / Yang, Y-N / Lee, I-S / Koh, S-E

Journal of musculoskeletal & neuronal interactions

2017 Band 17, Heft 4, Seite(n) 334–340

Abstract: Background: Despite widespread clinical use of weight bearing exercises to manage low bone mineral density (BMD) in children and adolescents with cerebral palsy (CP), previous studies have reported heterogeneous results on the effect of weight bearing ... ...

Abstract	Background: Despite widespread clinical use of weight bearing exercises to manage low bone mineral density (BMD) in children and adolescents with cerebral palsy (CP), previous studies have reported heterogeneous results on the effect of weight bearing exercise on BMD. Purpose: We performed the current meta-analysis to assess the effects of weight bearing exercise on increasing BMD in children who have CP with low BMD. Materials and methods: We searched PubMed, Cochrane, and Embase from inception through to October 2016 for studies that aims to investigate the effect of weight bearing exercise on BMD in children with CP. Following the searching result, the 118 relevant studies were reviewed and undergone selection process. Standardized mean difference (SMD), 95% confidence intervals (CIs) and p-values were calculated for analysis. Results: Three studies were ultimately included in the meta-analysis: one randomized-controlled study and two case-controlled studies. No significant difference was observed in the BMD of the lumbar spine between before treatment and after treatment (SMD,0.341; 95% CI,-0.647-1.330; p=0.449) but the BMD of the femur significantly improved after applying weight bearing exercise compared to pre-treatment values (SMD, 0.916; 95% CI, 0.382-1.114; p⟨0.001). Conclusions: Weight bearing exercise has a significant effect on improving BMD of the femur in children with CP.
Mesh-Begriff(e)	Adolescent ; Bone Density ; Cerebral Palsy/rehabilitation ; Child ; Female ; Humans ; Male ; Resistance Training/methods
Sprache	Englisch
Erscheinungsdatum	2017-12-01
Erscheinungsland	Greece
Dokumenttyp	Journal Article ; Meta-Analysis
ZDB-ID	2041366-X
ISSN	1108-7161
ISSN	1108-7161
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Functional neuroimaging studies in functional dyspepsia patients: a systematic review.

Lee, I-S / Wang, H / Chae, Y / Preissl, H / Enck, P

Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society

2016 Band 28, Heft 6, Seite(n) 793–805

Abstract: Background: There is increasing evidence in support of the presence of abnormal central changes (compared to healthy controls) in functional dyspepsia (FD) in addition to the peripheral changes in gastrointestinal tract.: Purpose: This systematic ... ...

Abstract	Background: There is increasing evidence in support of the presence of abnormal central changes (compared to healthy controls) in functional dyspepsia (FD) in addition to the peripheral changes in gastrointestinal tract. Purpose: This systematic review aims to provide an integrative understanding of the abnormal functional brain activity, visceral sensation, dyspeptic symptoms, and psychological changes of FD. Electronic and hand searches were conducted to identify functional neuroimaging studies involving FD patients. Sixteen studies were selected and divided into three categories: 10 resting state studies, three visceral distention studies, and three acupuncture studies. Changes were reported in several brain areas in FD patients including the frontal cortex, somatosensory cortex, insula, anterior cingulate cortex, thalamus, hippocampus, and amygdala. These brain activity changes were associated with visceral hypersensitivity, dyspeptic symptoms, poorer quality of life, anxiety, and depression. The results show that FD is associated with functional abnormalities in sensory and pain modulation, emotion, saliency, and homeostatic processing regions. The diversity of conditions, heterogeneous results, poorly standardized diagnoses of FD, and various comorbidities may be responsible for the variability in the results.
Sprache	Englisch
Erscheinungsdatum	2016-06
Erscheinungsland	England
Dokumenttyp	Journal Article ; Review
ZDB-ID	1186328-6
ISSN	1365-2982 ; 1350-1925
ISSN (online)	1365-2982
ISSN	1350-1925
DOI	10.1111/nmo.12793
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel: New constructive heuristics for the total weighted tardiness problem

Yoon, S. H / Lee, I. S

Journal of the Operational Research Society : OR Vol. 62, No. 1 , p. 232-237

2011 Band 62, Heft 1, Seite(n) 232–237

Verfasserangabe	S. H. Yoon and I. S. Lee
Sprache	Englisch
Verlag	Palgrave
Erscheinungsort	Basingstoke, Hampshire
Dokumenttyp	Artikel
ZDB-ID	716033-1 ; 2069025-3
ISSN	0030-3623 ; 1473-2858 ; 1473-284X
ISSN	0030-3623 ; 1473-2858 ; 1473-284X
Datenquelle	ECONomics Information System

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Artikel: Network Approaches to the genetic dissection of phenotypes in animals and humans

Lee, I.S., Yonsei University, Seoul, Republic of korea

Animal Cells and Systems

(Apr 2013) Band v. 17, Heft (2), Seite(n) p. 75–79

Abstract: various genome-wide approaches to identifying the genetic components that underlie phenotypes in animals and humans have been developed during the last several decades. The relationship between gene and phenotype, however, cannot be represented by a ... ...

Abstract	various genome-wide approaches to identifying the genetic components that underlie phenotypes in animals and humans have been developed during the last several decades. The relationship between gene and phenotype, however, cannot be represented by a simple one-to-one correspondence. Rather, many genes are typically related to a single phenotype and many phenotypes can be associated with a single gene, a major theme not only identify the genetic components involved but also the relationships between genes.
Schlagwörter	COMPLEXACION ; COMPLEXATION ; COMPLEXING
Sprache	Englisch
Dokumenttyp	Artikel
ISSN	1976-8354
Datenquelle	AGRIS - International Information System for the Agricultural Sciences and Technology

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Artikel ; Online: Comparative outcomes of robot-assisted minimally invasive versus open esophagectomy in patients with esophageal squamous cell carcinoma: a propensity score-weighted analysis.

Yun, J K / Chong, B K / Kim, H J / Lee, I-S / Gong, C-S / Kim, B S / Lee, G D / Choi, S / Kim, H R / Kim, D K / Park, S-I / Kim, Y-H

Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

2019 Band 33, Heft 5

Abstract: Robots are increasingly used in minimally invasive surgery. We evaluated the clinical benefits of robot-assisted minimally invasive esophagectomy (RAMIE) in comparison with the conventional open esophageal surgery. From 2012 to 2016, 371 patients with ... ...

Abstract	Robots are increasingly used in minimally invasive surgery. We evaluated the clinical benefits of robot-assisted minimally invasive esophagectomy (RAMIE) in comparison with the conventional open esophageal surgery. From 2012 to 2016, 371 patients with esophageal squamous cell carcinoma underwent an Ivor Lewis or McKeown procedure at our institution. Of these, 130 patients underwent laparoscopic gastric conduit formation followed by RAMIE, whereas 241 patients underwent conventional esophageal surgery, including laparotomy and open esophagectomy (OE). We compared the short- and long-term clinical outcomes of these patients using the propensity score-based inverse probability of treatment weighting technique (IPTW). Among the early outcomes, the OE group showed a higher incidence of pneumonia (P = 0.035) and a higher requirement for vasopressors (P = 0.001). Regarding the long-term outcomes, all-cause mortality was significantly higher (P = 0.001) and disease-free survival was lower (P = 0.006) in the OE group. Wound-related problems also occurred more frequently in the OE group (P = 0.020) during the long-term follow-up. There was no statistical intergroup difference in the recurrence rates (P = 0.191). The Cox proportional-hazard analysis demonstrated that wound problems (HR 0.16, 95% CI 0.02-0.57; P = 0.017), pneumonia (HR 0.23, 95% CI 0.06-0.68; P = 0.019), and use of vasopressors (HR 0.14, 95% CI 0.08-0.25; P = 0.001) were independent predictors of mortality. RAMIE could be a better surgical option for selected patients with esophageal squamous cell carcinoma.
Mesh-Begriff(e)	Esophageal Neoplasms/surgery ; Esophageal Squamous Cell Carcinoma/surgery ; Esophagectomy/adverse effects ; Head and Neck Neoplasms ; Humans ; Minimally Invasive Surgical Procedures ; Neoplasm Recurrence, Local ; Postoperative Complications/epidemiology ; Postoperative Complications/etiology ; Propensity Score ; Robotic Surgical Procedures ; Robotics ; Treatment Outcome
Sprache	Englisch
Erscheinungsdatum	2019-11-04
Erscheinungsland	United States
Dokumenttyp	Journal Article
ZDB-ID	639470-x
ISSN	1442-2050 ; 1120-8694
ISSN (online)	1442-2050
ISSN	1120-8694
DOI	10.1093/dote/doz071
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Biomimetic fibronectin/mineral and osteogenic growth peptide/mineral composites synthesized on calcium phosphate thin films.

Chen, C / Qiu, Z Y / Zhang, S M / Lee, I-S

Chemical communications (Cambridge, England)

2011 Band 47, Heft 39, Seite(n) 11056–11058

Abstract: Composites of fibronectin/mineral and osteogenic growth peptide/mineral were synthesized on calcium phosphate coated substrates immersed in Dulbecco's phosphate-buffered saline solution containing biomolecules. The kinetics of coprecipitation for two ... ...

Abstract	Composites of fibronectin/mineral and osteogenic growth peptide/mineral were synthesized on calcium phosphate coated substrates immersed in Dulbecco's phosphate-buffered saline solution containing biomolecules. The kinetics of coprecipitation for two biomolecules was similar, and the biomolecules participated in the formation of the crystal latticework and influenced the mineral structure and composition.
Mesh-Begriff(e)	Biomimetic Materials/chemical synthesis ; Biomimetic Materials/metabolism ; Calcium Phosphates/chemistry ; Calcium Phosphates/metabolism ; Chemical Precipitation ; Fibronectins/chemistry ; Fibronectins/metabolism ; Histones/chemistry ; Histones/metabolism ; Intercellular Signaling Peptides and Proteins/chemistry ; Intercellular Signaling Peptides and Proteins/metabolism ; Minerals/chemistry ; Minerals/metabolism
Chemische Substanzen	Calcium Phosphates ; Fibronectins ; Histones ; Intercellular Signaling Peptides and Proteins ; Minerals ; osteogenic growth peptide (132996-61-3) ; calcium phosphate (97Z1WI3NDX)
Sprache	Englisch
Erscheinungsdatum	2011-10-21
Erscheinungsland	England
Dokumenttyp	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1472881-3
ISSN	1364-548X ; 1359-7345 ; 0009-241X
ISSN (online)	1364-548X
ISSN	1359-7345 ; 0009-241X
DOI	10.1039/c1cc13480a
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel: Extraction and on-line concentration of flavonoids in Brassica oleracea by capillary electrophoresis using large volume sample stacking

Lee, I. S. L. / Boyce, M. C. / Breadmore, M. C.

Food chemistry

2012 Band 133, Heft 1, Seite(n) 205

Sprache	Englisch
Dokumenttyp	Artikel
ZDB-ID	243123-3
ISSN	0308-8146
Datenquelle	Current Contents Ernährung, Umwelt, Agrar

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Artikel ; Online: Polynucleotide phosphorylase (PNPase) is required for Salmonella enterica serovar Typhimurium colonization in swine.

Bearson, S M D / Bearson, B L / Lee, I S / Kich, J D

Microbial pathogenesis

2013 Band 65, Seite(n) 63–66

Abstract: The pnp gene encodes polynucleotide phosphorylase, an exoribonuclease involved in RNA processing and degradation. A mutation in the pnp gene was previously identified by our group in a signature-tagged mutagenesis screen designed to search for Salmonella ...

Abstract	The pnp gene encodes polynucleotide phosphorylase, an exoribonuclease involved in RNA processing and degradation. A mutation in the pnp gene was previously identified by our group in a signature-tagged mutagenesis screen designed to search for Salmonella enterica serovar Typhimurium genes required for survival in an ex vivo swine stomach content assay. In the current study, attenuation and colonization potential of a S. Typhimurium pnp mutant in the porcine host was evaluated. Following intranasal inoculation with 10(9) cfu of either the wild-type S. Typhimurium χ4232 strain or an isogenic derivative lacking the pnp gene (n = 5/group), a significant increase (p < 0.05) in rectal temperature (fever) was observed in the pigs inoculated with wild-type S. Typhimurium compared to the pigs inoculated with the pnp mutant. Fecal shedding of the pnp mutant was significantly reduced during the 7-day study compared to the wild-type strain (p < 0.001). Tissue colonization was also significantly reduced in the pigs inoculated with the pnp mutant compared to the parental strain, including the tonsils, ileocecal lymph nodes, Peyer's Patch region of the ileum, cecum and contents of the cecum (p < 0.05). The data indicate that the pnp gene is required for S. Typhimurium virulence and gastrointestinal colonization of the natural swine host.
Mesh-Begriff(e)	Animals ; Feces/microbiology ; Gastrointestinal Tract/microbiology ; Mutation ; Polyribonucleotide Nucleotidyltransferase/genetics ; Polyribonucleotide Nucleotidyltransferase/metabolism ; Salmonella Infections, Animal/enzymology ; Salmonella Infections, Animal/genetics ; Salmonella Infections, Animal/microbiology ; Salmonella typhimurium/enzymology ; Salmonella typhimurium/genetics ; Swine/microbiology ; Swine Diseases/enzymology ; Swine Diseases/genetics ; Swine Diseases/microbiology
Chemische Substanzen	Polyribonucleotide Nucleotidyltransferase (EC 2.7.7.8)
Sprache	Englisch
Erscheinungsdatum	2013-12
Erscheinungsland	England
Dokumenttyp	Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
ZDB-ID	632772-2
ISSN	1096-1208 ; 0882-4010
ISSN (online)	1096-1208
ISSN	0882-4010
DOI	10.1016/j.micpath.2013.10.001
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Diagnostic Performance of Multidetector Computerized Tomography in the Detection of Abdominal Complications Early and Late After Liver Transplantation: A 10-Year Experience.

Lee, I S / Park, S H / Choi, S J / Shim, Y / Ahn, S-J / Kim, K W / Kim, K K / Jeong, Y M / Choe, Y H

Transplantation proceedings

2018 Band 50, Heft 10, Seite(n) 3673–3680

Abstract: Background: Multidetector computerized tomography (MDCT) is considered to be a fast noninvasive diagnostic technique for the evaluation of postoperative complications in patients with liver transplantation (LT). However, its role has not been fully ... ...

Abstract	Background: Multidetector computerized tomography (MDCT) is considered to be a fast noninvasive diagnostic technique for the evaluation of postoperative complications in patients with liver transplantation (LT). However, its role has not been fully established in the diagnosis for detecting complications after liver transplantation. The aim of this work was to evaluate the diagnostic performance of MDCT for detecting abdominal complications in the early and late periods after LT. Methods: We retrospectively enrolled 75 patients who had undergone LT from March 2006 to January 2010, followed by MDCT from March 2006 to November 2017. Patients were divided into 2 groups according to the timing after LT: within the first 3 months (early period) or ≥3 months after LT (late period). We evaluated vascular, biliary, and other complications on MDCT. Angiography, endoscopic retrograde cholangiography, and percutaneous transhepatic cholangiography were used as reference standards. Results: We initially found 77 complications in 45 patients (60.0%) with the use of MDCT. After comparison with the reference standards, 83 complications were diagnosed in 49 patients (65.3%). Forty-seven complications (34 vascular, 10 biliary, 3 other complications) were diagnosed in 33 patients (44.0%) during the early period, and 36 complications (6 vascular, 20 biliary, 10 other complications) were detected in 27 patients (36.0%) in the late period. The sensitivity, specificity, and diagnostic accuracy of MDCT for diagnosing overall complications were, respectively, 93.6%, 90.2%, and 92.0% in the early period (for vascular complications: 97.1%, 92.6%, and 94.3%,; for biliary complications: 80.0%, 100%, and 97.7%) and 77.8%, 98.1%, and 89.8% in the late period (for vascular complications: 83.3%, 100%, and 98.9%; for biliary complications: 65.0%, 98.6%, and 90.9%). Conclusions: Although MDCT in the late period should be interpreted with caution in patients with suspected biliary complication, MDCT is a reliable diagnostic technique for the identification of early and late abdominal complications after LT.
Mesh-Begriff(e)	Adult ; Female ; Humans ; Liver Transplantation/adverse effects ; Male ; Middle Aged ; Multidetector Computed Tomography/methods ; Postoperative Complications/diagnostic imaging ; Postoperative Complications/etiology ; Retrospective Studies ; Sensitivity and Specificity
Sprache	Englisch
Erscheinungsdatum	2018-09-10
Erscheinungsland	United States
Dokumenttyp	Journal Article
ZDB-ID	82046-5
ISSN	1873-2623 ; 0041-1345
ISSN (online)	1873-2623
ISSN	0041-1345
DOI	10.1016/j.transproceed.2018.09.016
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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