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  1. Buch ; Online: Oriental, Black, and White

    Lee, Josephine

    The Formation of Racial Habits in American Theater

    2022  

    Schlagwörter Black & Asian studies ; Theatre studies ; History of the Americas ; Cross-racial performance ; blackface minstrelsy ; yellowface ; American orientalism ; racial stereotypes ; all-Black musical ; nineteenth-century American theater ; racial habit ; Aladdin ; Shuffle Along ; Ira Aldridge ; Japanese Tommy ; Bert Williams ; George Walker ; In Dahomey ; Abyssinia ; Aida Overton Walker ; Salome ; Chinese laundry ; representations of the Philippine-American War ; Flower Drum Song ; Juanita Long Hall ; Princess Sotanki ; Sissieretta Jones ; Afro-Asian ; chop suey
    Sprache Englisch
    Umfang 1 electronic resource (344 pages)
    Verlag The University of North Carolina Press
    Erscheinungsort Chapel Hill
    Dokumenttyp Buch ; Online
    Anmerkung English
    HBZ-ID HT030613525
    ISBN 9781469669632 ; 1469669633
    Datenquelle ZB MED Katalog Medizin, Gesundheit, Ernährung, Umwelt, Agrar

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  2. Buch: Practical Emergency Resuscitation and Critical Care

    Lee, Jarone / Shah, Kaushal

    2023  

    Umfang 648 p.
    Verlag Cambridge University Press
    Dokumenttyp Buch
    Anmerkung PDA Manuell_25
    Format 158 x 229 x 32
    ISBN 9781009055628 ; 1009055623
    Datenquelle PDA

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  3. Buch ; Online: Embracing Analytics in the Drinking Water Industry

    Lee, Juneseok

    2022  

    Schlagwörter Environmental science, engineering & technology ; Industrial applications of scientific research & technological innovation ; Mining technology & engineering ; Science ; Environmental Science ; Applied Sciences ; Technology & Engineering ; Mining
    Sprache 0|e
    Umfang 1 Online-Ressource
    Verlag IWA Publishing
    Dokumenttyp Buch ; Online
    Anmerkung English ; Open Access
    HBZ-ID HT021616994
    ISBN 9781789062380 ; 1789062381
    Datenquelle ZB MED Katalog Medizin, Gesundheit, Ernährung, Umwelt, Agrar

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  4. Buch ; Online ; E-Book: Model-assisted Bayesian designs for dose finding and optimization

    Yuan, Ying / Lin, Ruitao / Lee, J. Jack

    methods and applications

    (Chapman & Hall/CRC biostatistics series)

    2023  

    Abstract: Bayesian adaptive designs provide a critical approach to improve the efficiency and success rate of drug development that has been embraced by the US Food and Drug Administration (FDA). This is particularly important for early phase trials as they forms ...

    Verfasserangabe Ying Yuan, Ruitao Lin, J. Jack Lee
    Serientitel Chapman & Hall/CRC biostatistics series
    Abstract "Bayesian adaptive designs provide a critical approach to improve the efficiency and success rate of drug development that has been embraced by the US Food and Drug Administration (FDA). This is particularly important for early phase trials as they forms the basis for the development and success of subsequent phase II and III trials. The objective of this book is to describes the state-of-the-art model-assisted designs to faciliate and accelerate the use of novel adaptive designs for early phase clinical trials. Model-assisted designs possess avant-garde features where superiority meets simplicity. Model-assisted designs enjoy exceptional performance comparable to more complicated model-based adaptive designs, yet their decision rules often can be pre-tabulated and included in the protocol-making implementation as simple as conventional algorithm-based designs. An example is the Bayesian optimal interval (BOIN) design, the first dose-finding design to receive the fit-for-purpose designation from the FDA. This designation underscores the regulatory agency's support of the use of the novel adaptive design to improve drug development. Features Represents the first book to provide comprehensive coverage of model-assisted designs for various types of dose-finding and optimization clinical trials Describes the up-to-date theory and practice for model-assisted designs Presents many practical challenges and issues arising from early-phase clinical trials Illustrates with many real trial applications Offers numerous tips and guidance on designing dose finding and optimization trials Provides step-by-step illustration of using software to design trials Develops a companion website (www.trialdesign.org) to provide easy-to-use software to assist learning and implementing model-assisted designs Written by internationally recognized research leaders who pioneered model-assisted designs from the University of Texas MD Anderson Cancer Center, this book shows how model-assisted designs can greatly improve the efficiency and simplify the conduct of early-phase dose finding and optimization trials. It should therefore be a very useful practical reference for biostatisticians, clinicians working in clinical trials, and drug regulatory professionals, as well as graduate students of biostatistics. Novel model-assisted designs showcase the new KISS principle: Keep it simple and smart!"--
    Mesh-Begriff(e) Drug Development/methods ; Drug Design/methods ; Drug Dosage Calculations ; Models, Statistical ; Bayes Theorem ; Clinical Trials, Phase I as Topic
    Schlagwörter Pharmaceutical arithmetic ; Drug development/Statistical methods ; Drug development
    Thema/Rubrik (Code) 615.1/9
    Sprache Englisch
    Erscheinungsverlauf 2023-2023
    Umfang 1 online resource (xiii, 219 pages) :, illustrations.
    Ausgabenhinweis First edition.
    Verlag CRC Press
    Erscheinungsort Boca Raton, Florida ; London ; New York
    Dokumenttyp Buch ; Online ; E-Book
    Bemerkung Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 0-429-05278-2 ; 0-429-62683-5 ; 0-367-14624-X ; 978-0-429-05278-1 ; 978-0-429-62683-8 ; 978-0-367-14624-5
    Datenquelle ZB MED Katalog Medizin, Gesundheit, Ernährung, Umwelt, Agrar

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  5. Artikel: The potential use of bromelain as a natural oral medicine having anticarcinogenic activities

    lee, jungha

    Food Science & Nutrition, 7(5):1656-1667

    2019  

    Abstract: Bromelain (BR), a protease extracted from Ananas comosus, reportedly possesses pharmacological activities including the reduction of thrombogenesis, and antihypertensive, and antimicrobial effects. This study aimed to investigate the potential effects of ...

    Abstract Bromelain (BR), a protease extracted from Ananas comosus, reportedly possesses pharmacological activities including the reduction of thrombogenesis, and antihypertensive, and antimicrobial effects. This study aimed to investigate the potential effects of BR on oral cancer cells. The effect of BR on the viability of Ca9‐22 and SCC25 cells was determined using the MTT assay. These cells were also treated with different doses of BR, and Western blotting was conducted to monitor apoptosis. Finally, flow cytometry analysis was performed to identify sub‐G1 populations of oral cancer cells. After treatment, the viability of both Ca9‐22 and SCC25 cells was markedly reduced, in a dose‐dependent manner. BR induced poly (ADP‐ribose) polymerase (PARP) and lamin A/C degradation, and generated cleavage products. Flow cytometry analysis showed that BR treatment significantly increased the sub‐G1 population. Our findings therefore indicate that BR has potential as a novel, natural anticarcinogenic medicine.
    Schlagwörter anticarcinogenic effect ; bromelain ; oral squamous cell carcinoma ; public oral health
    Sprache Englisch
    Dokumenttyp Artikel
    Datenquelle Fachrepositorium Lebenswissenschaften

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  6. Buch ; Online: Applications on Ultrasonic Wave

    Lee, Jaesun

    2021  

    Schlagwörter Technology: general issues ; tomographic imaging ; DHB algorithm ; noncontact ; air-coupled transducer ; steel wire rod ; nonlinear ultrasonic ; EMAT ; guided wave ; ultrasonic sensors ; GPS ; surface monitoring ; image processing ; dynamic time warping ; piezoelectric materials ; transversely isotropic material ; IEEE resonance method ; resonant and anti-resonant frequencies ; dynamic non-destructive evaluation ; acoustic wave ; scattering ; random rough surface ; impedance
    Umfang 1 electronic resource (112 pages)
    Verlag MDPI - Multidisciplinary Digital Publishing Institute
    Erscheinungsort Basel, Switzerland
    Dokumenttyp Buch ; Online
    Anmerkung English ; Open Access
    HBZ-ID HT021289584
    ISBN 9783036511214 ; 3036511210
    Datenquelle ZB MED Katalog Medizin, Gesundheit, Ernährung, Umwelt, Agrar

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  7. Buch ; Online: Nazism and Neo-Nazism in Film and Media

    Lee , Jason

    2018  

    Schlagwörter Digital, video and new media arts ; Film history, theory or criticism ; Film theory ; video art
    Sprache Englisch
    Umfang 1 electronic resource (264 pages)
    Verlag Amsterdam University Press
    Erscheinungsort Amsterdam
    Dokumenttyp Buch ; Online
    Anmerkung English
    HBZ-ID HT030721915
    ISBN 9789089649362 ; 9089649360
    Datenquelle ZB MED Katalog Medizin, Gesundheit, Ernährung, Umwelt, Agrar

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  8. Artikel ; Online: Interventricular Septal Aneurysm: Reconsidering the Risk.

    Lee, Jongmin

    Journal of the Korean Society of Radiology

    2024  Band 85, Heft 1, Seite(n) 215–216

    Sprache Englisch
    Erscheinungsdatum 2024-01-22
    Erscheinungsland Korea (South)
    Dokumenttyp Editorial
    ISSN 2951-0805
    ISSN (online) 2951-0805
    DOI 10.3348/jksr.2023.0159
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel: Disparities in the impact of economic well-being on self-esteem in adulthood: Race and ethnicity.

    Lee, Jaewon

    World journal of psychiatry

    2024  Band 14, Heft 2, Seite(n) 296–307

    Abstract: Background: Most studies have defined economic well-being as socioeconomic status, with little attention given to whether other indicators influence self-esteem. Little is known about racial/ethnic disparities in the relationship between economic well- ... ...

    Abstract Background: Most studies have defined economic well-being as socioeconomic status, with little attention given to whether other indicators influence self-esteem. Little is known about racial/ethnic disparities in the relationship between economic well-being and self-esteem during adulthood.
    Aim: To explore the impact of economic well-being on self-esteem in adulthood and differences in the association across race/ethnicity.
    Methods: The current study used data from the National Longitudinal Survey of Youth 1979. The final sample consisted of 2267 African Americans, 1425 Hispanics, and 3678 non-Hispanic Whites. Ordinary linear regression analyses and logistic regression analyses were conducted.
    Results: African Americans and Hispanics were more likely to be in poverty in comparison with non-Hispanic Whites. More African Americans were unemployed than Whites. Those who received fringe benefits, were more satisfied with jobs, and were employed were more likely to have higher levels of self-esteem. Poverty was negatively associated with self-esteem. Interaction effects were found between African Americans and job satisfaction predicting self-esteem.
    Conclusion: The role of employers is important in cultivating employees' self-esteem. Satisfactory outcomes or feelings of happiness from the workplace may be more important to non-Hispanic Whites compared to African Americans and Hispanics.
    Sprache Englisch
    Erscheinungsdatum 2024-02-19
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ISSN 2220-3206
    ISSN 2220-3206
    DOI 10.5498/wjp.v14.i2.296
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  10. Artikel: Tetrahydrocannabinol and dopamine D1 receptor.

    Lee, Jiwon

    Frontiers in neuroscience

    2024  Band 18, Seite(n) 1360205

    Abstract: Dopamine is a hormone that is released by the adrenal gland and influences motor control and motivation. Dopamine is known to have 5 receptors which are D1, D2, D3, D4 and D5, which are further categorized into 2 families: D1 family and D2 family. The D1 ...

    Abstract Dopamine is a hormone that is released by the adrenal gland and influences motor control and motivation. Dopamine is known to have 5 receptors which are D1, D2, D3, D4 and D5, which are further categorized into 2 families: D1 family and D2 family. The D1 family is known to play a role in motivation and motor control whereas the D2 family is known to affect attention and sleep. THC, a type of cannabinoid, can lead to feelings of euphoria, anxiety, fear, distrust, or panic. THC is known to affect dopamine in regions such as the anterior cingulate cortex (ACC), and plays a role in fundamental cognitive processes. Although there is a vast amount of research between the relationship of THC on dopamine, there continues to be limited research in relation to THC on dopamine receptors. The D1 receptor plays a role in several essential functions, such as memory, attention, impulse control, regulation of renal function, and locomotion. Accordingly, this review is intended to summarize the relationship between THC and D1 receptors, highlighting key gaps in the literature and avenues for future research.
    Sprache Englisch
    Erscheinungsdatum 2024-02-14
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2411902-7
    ISSN 1662-453X ; 1662-4548
    ISSN (online) 1662-453X
    ISSN 1662-4548
    DOI 10.3389/fnins.2024.1360205
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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