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  1. Article ; Online: Electrochemiluminescent determination of sphingomyelin in milk based on polyaniline hydrogel coupled with enzyme-functionalized Au nanoparticles.

    Wang, Chang-Ji / Li, Han-Xu

    Analytical biochemistry

    2023  Volume 677, Page(s) 115266

    Abstract: In this paper, sphingomyelin (SM) is detected by a polyaniline hydrogel and Au nanoparticles with enzyme modified electrode (GCE/PAniH/AuNPs@enzyme). After a battery of enzymic degradation, SM can generate ... ...

    Abstract In this paper, sphingomyelin (SM) is detected by a polyaniline hydrogel and Au nanoparticles with enzyme modified electrode (GCE/PAniH/AuNPs@enzyme). After a battery of enzymic degradation, SM can generate H
    MeSH term(s) Animals ; Gold ; Sphingomyelins ; Metal Nanoparticles ; Milk ; Hydrogels ; Hydrogen Peroxide ; Luminescent Measurements ; Luminol ; Biosensing Techniques/methods ; Limit of Detection ; Electrochemical Techniques
    Chemical Substances Gold (7440-57-5) ; polyaniline ; Sphingomyelins ; Hydrogels ; Hydrogen Peroxide (BBX060AN9V) ; Luminol (5EXP385Q4F)
    Language English
    Publishing date 2023-07-29
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1110-1
    ISSN 1096-0309 ; 0003-2697
    ISSN (online) 1096-0309
    ISSN 0003-2697
    DOI 10.1016/j.ab.2023.115266
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 389: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  2. Article ; Online: Electrochemiluminescent determination of sphingomyelin in milk based on polyaniline hydrogel coupled with enzyme-functionalized Au nanoparticles

    Wang, Chang-Ji / Li, Han-Xu

    Analytical Biochemistry. 2023 Sept., v. 677 p.115266-

    2023  

    Abstract: In this paper, sphingomyelin (SM) is detected by a polyaniline hydrogel and Au nanoparticles with enzyme modified electrode (GCE/PAniH/AuNPs@enzyme). After a battery of enzymic degradation, SM can generate H₂O₂ and enhance the electrochemiluminescence ( ... ...

    Abstract In this paper, sphingomyelin (SM) is detected by a polyaniline hydrogel and Au nanoparticles with enzyme modified electrode (GCE/PAniH/AuNPs@enzyme). After a battery of enzymic degradation, SM can generate H₂O₂ and enhance the electrochemiluminescence (ECL) response of luminol, which endows the sensor with good sensitivity, specifiity and repeatability. Additionally, the proposed ECL biosensor displays good analytical performances with a wide range from 10.0 μg·mL⁻¹ to 250.0 μg·mL⁻¹ as well as a low detection limit of 3.50 μg·mL⁻¹ (S/N = 3). When the ECL biosensor is used in the detection of SM in milk samples, satisfactory results are obtained, indicating that PAniH/AuNPs@enzyme will serve as a promising ECL material in the applications of H₂O₂-related bioassay in the future.
    Keywords bioassays ; biosensors ; detection limit ; electrochemiluminescence ; electrodes ; enzymes ; hydrogels ; milk ; nanogold ; polyaniline ; sphingomyelins ; Sphingomyelin ; Luminol
    Language English
    Dates of publication 2023-09
    Publishing place Elsevier Inc.
    Document type Article ; Online
    ZDB-ID 1110-1
    ISSN 1096-0309 ; 0003-2697
    ISSN (online) 1096-0309
    ISSN 0003-2697
    DOI 10.1016/j.ab.2023.115266
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    In stock of ZB MED Bonn / Germany

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  3. Article ; Online: Synthesis and Evaluation of Novel Nitric Oxide-Donating Ligustrazine Derivatives as Potent Antiplatelet Aggregation Agents.

    Li, Han-Xu / Tian, Jian-Hui / Li, Hua-Yu / Wan, Xin / Zou, Yu

    Molecules (Basel, Switzerland)

    2023  Volume 28, Issue 8

    Abstract: Antiplatelet aggregation agents have demonstrated clinical benefits in the treatment of ischemic stroke. In our study, a series of novel nitric oxide (NO)-donating ligustrazine derivatives were designed and synthesized as antiplatelet aggregation agents. ...

    Abstract Antiplatelet aggregation agents have demonstrated clinical benefits in the treatment of ischemic stroke. In our study, a series of novel nitric oxide (NO)-donating ligustrazine derivatives were designed and synthesized as antiplatelet aggregation agents. They were evaluated for the inhibitory effect on 5'-diphosphate (ADP)-induced and arachidonic acid (AA)-induced platelet aggregation in vitro. The results showed that compound
    MeSH term(s) Platelet Aggregation Inhibitors/pharmacology ; Nitric Oxide/pharmacology ; Platelet Aggregation ; Pyrazines/pharmacology ; Structure-Activity Relationship ; Arachidonic Acid/pharmacology
    Chemical Substances Platelet Aggregation Inhibitors ; tetramethylpyrazine (V80F4IA5XG) ; Nitric Oxide (31C4KY9ESH) ; Pyrazines ; Arachidonic Acid (27YG812J1I)
    Language English
    Publishing date 2023-04-11
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules28083355
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    Zs.MO 81: Show issues

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  4. Article ; Online: The clinical feasibility and performance of an orthogonal X-ray imaging system for image-guided radiotherapy in nasopharyngeal cancer patients: Comparison with cone-beam CT.

    Zhao, Li-Rong / Zhou, Yi-Bing / Li, Guang-Hui / Li, Qi-Ming / Yang, Ding-Qiang / Li, Han-Xu / Wan, Jiu-Qing / Sun, Jian-Guo

    Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)

    2015  Volume 32, Issue 1, Page(s) 266–271

    Abstract: The demand for greater accuracy of intensity-modulated radiotherapy (IMRT) has driven the development of more advanced verification systems for image-guided radiotherapy (IGRT). The purpose of this study is to investigate setup discrepancies measured ... ...

    Abstract The demand for greater accuracy of intensity-modulated radiotherapy (IMRT) has driven the development of more advanced verification systems for image-guided radiotherapy (IGRT). The purpose of this study is to investigate setup discrepancies measured between an orthogonal X-ray guidance system (XGS-10) and cone-beam computed tomography (CBCT) of Varian in the IMRT of patients with nasopharyngeal cancer (NPC). The setup errors measured by XGS-10 and CBCT at the treatment unit with respect to the planning CTs were recorded for 30 patients with NPC. The differences in residual setup errors between XGS-10 system and CBCT were computed and quantitatively analyzed. The time of image acquisition and image registration was recorded. The radiation doses delivered by CBCT and XGS-10 were measured using PTW0.6CC ionization chambers and a water phantom. The differences between setup errors measured by the XGS-10 system and CBCT were generally <1.5 mm for translations, indicating a reasonably good agreement between the two systems for patients with NPC in the translation directions of A-P (P = 0.856), L-R (P = 0.856) and S-I (P = 0.765). Moreover, compared with CBCT, XGS-10 took much shorter image acquisition and registration time (P <0.001) and delivered only a small fraction of extra radiation dose to the patients (P <0.001). These results indicate that XGS-10 offers high localization accuracy similar to CBCT and additional benefits including prompt imaging process, low imaging radiation exposure, real time monitoring, which therefore represents a potential attractive alternative to CBCT for clinical use.
    MeSH term(s) Algorithms ; Carcinoma ; Computer Simulation ; Cone-Beam Computed Tomography/methods ; Equipment Design ; Humans ; Image Processing, Computer-Assisted ; Nasopharyngeal Carcinoma ; Nasopharyngeal Neoplasms/radiotherapy ; Phantoms, Imaging ; Radiation Dosage ; Radiography/methods ; Radiometry ; Radiotherapy Planning, Computer-Assisted/methods ; Radiotherapy, Image-Guided/methods ; Radiotherapy, Intensity-Modulated ; Reproducibility of Results ; Retrospective Studies ; Water ; X-Rays
    Chemical Substances Water (059QF0KO0R)
    Language English
    Publishing date 2015-12-15
    Publishing country Italy
    Document type Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1122650-x
    ISSN 1724-191X ; 1120-1797
    ISSN (online) 1724-191X
    ISSN 1120-1797
    DOI 10.1016/j.ejmp.2015.11.010
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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2941: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  5. Article: [Study on the occurrence of ferrum in coal by ultrasound-assisted sequential chemical extraction].

    Xiong, Jin-Yu / Li, Han-Xu / Dong, Zhong-Bing / Zhang, Song / Qian, Ning-Bo / Wu, Cheng-Li

    Huan jing ke xue= Huanjing kexue

    2014  Volume 34, Issue 11, Page(s) 4490–4494

    Abstract: To reveal the occurrence of Ferrum in coal, seven coal samples were selected according to the different contents of ferric oxide in the coal ash, and the content of Ferric element was determined by atomic absorption spectrophotometer (AAS) using nitric ... ...

    Abstract To reveal the occurrence of Ferrum in coal, seven coal samples were selected according to the different contents of ferric oxide in the coal ash, and the content of Ferric element was determined by atomic absorption spectrophotometer (AAS) using nitric acid-perchloric acid-hydrofluoric acid wet digestion. Modes of occurrence of ferrium in the seven coal samples were studied by AAS using ultrasound-assisted sequential chemical extraction experiment (SCEE). Ultrasound promoted the contact of the extraction reagent with the coal particles and enhanced the dissolution process by producing characteristic acoustic cavitations, which greatly shortened the experimental time. The total amount of ferrium obtained by sequential extraction was approximate to the result of wet digestion, which indicated the procedure of SCEE was reasonable. The results showed that the ferric element mainly occurred in forms of carbonate state, Fe-Mn oxides state, sulfide state, sialic state and organic bound Fe in these coal samples. Among the various forms of these occurrences, the content of carbonate was the least, below 3.1%, while the content of sulfide was the dominant occurrence, ranging from 40% to 81.5%.
    MeSH term(s) Carbonates/analysis ; Chemical Fractionation/methods ; Coal/analysis ; Coal Ash/analysis ; Ferric Compounds/analysis ; Spectrophotometry, Atomic ; Sulfides/analysis ; Ultrasonics
    Chemical Substances Carbonates ; Coal ; Coal Ash ; Ferric Compounds ; Sulfides ; ferric oxide (1K09F3G675)
    Language Chinese
    Publishing date 2014-01-22
    Publishing country China
    Document type Journal Article
    ISSN 0250-3301
    ISSN 0250-3301
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