Artikel: The 21-Gene Recurrence Score Assay Improved Multidisciplinary Treatment Compliance in Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Breast Cancer Patients: An Analysis of 2,323 Patients.
2024
Abstract: Purpose: The 21-gene recurrence score (RS) can guide adjuvant chemotherapy decisions in the multidisciplinary treatment (MDT) of patients with early breast cancer. This study aimed to evaluate the influence of the 21-gene RS assay on patient' compliance ...
Abstract | Purpose: The 21-gene recurrence score (RS) can guide adjuvant chemotherapy decisions in the multidisciplinary treatment (MDT) of patients with early breast cancer. This study aimed to evaluate the influence of the 21-gene RS assay on patient' compliance with MDT and its association with disease outcomes. Methods: Patients diagnosed with pN0-1, hormone receptor-positive, human epidermal growth factor receptor-2-negative breast cancer between January 2013 and June 2019 were enrolled. A logistic regression model was used to identify parameters associated with treatment adherence. Prognostic indicators were evaluated using the Cox proportional hazard models. Results: After the assay, patients were less likely to violate the treatment plan (14.9% vs. 23.1%, Conclusion: The 21-gene RS assay improved the MDT compliance rate in patients with early breast cancer. Adherence to MDT is associated with a better prognosis. |
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Sprache | Englisch |
Erscheinungsdatum | 2024-04-11 |
Erscheinungsland | Korea (South) |
Dokumenttyp | Journal Article |
ZDB-ID | 2559753-X |
ISSN | 2092-9900 ; 1738-6756 |
ISSN (online) | 2092-9900 |
ISSN | 1738-6756 |
DOI | 10.4048/jbc.2023.0248 |
Datenquelle | MEDical Literature Analysis and Retrieval System OnLINE |
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