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  1. Artikel ; Online: Construction of Harmful Gas Monitoring System in Coal Mine Working Environment

    Li Yijie

    E3S Web of Conferences, Vol 252, p

    2021  Band 03057

    Abstract: In order to improve the accuracy, sensitivity, reliability, stability and maintainability of the coal mine safety monitoring system, and enhance the coal mine safety guarantee ability, combined with the national coal mine environmental monitoring network ...

    Abstract In order to improve the accuracy, sensitivity, reliability, stability and maintainability of the coal mine safety monitoring system, and enhance the coal mine safety guarantee ability, combined with the national coal mine environmental monitoring network construction scheme and the coal mine safety production and environmental monitoring management regulations, the coal mine safety production status and environmental data are analyzed. In order to improve the production efficiency and provide reliable guarantee for the safety production of coal mine, the monitoring system of harmful gas in the working site of coal mine roadway is established.
    Schlagwörter Environmental sciences ; GE1-350
    Sprache Englisch
    Erscheinungsdatum 2021-01-01T00:00:00Z
    Verlag EDP Sciences
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  2. Artikel ; Online: Construction of ring monitoring network for river and lake environmental monitoring system

    Li Yijie

    E3S Web of Conferences, Vol 257, p

    2021  Band 03048

    Abstract: With the continuous improvement of the level of science and technology in China, people’s desire for green water and blue sky is becoming more and more intense. Water pollution, air pollution, soil pollution and other issues always affect the lives of ... ...

    Abstract With the continuous improvement of the level of science and technology in China, people’s desire for green water and blue sky is becoming more and more intense. Water pollution, air pollution, soil pollution and other issues always affect the lives of residents. Environmental detection is the basic work of environmental protection. In this paper, based on the problems of environmental monitoring of rivers and lakes, we set up a ring network for environmental monitoring of rivers and lakes. The system is mainly composed of sensor nodes and monitoring center to monitor the main indicators of river and lake environment. In order to ensure people’s high requirements and high standards for the environment. To realize the complete monitoring of rivers and lakes.
    Schlagwörter Environmental sciences ; GE1-350
    Sprache Englisch
    Erscheinungsdatum 2021-01-01T00:00:00Z
    Verlag EDP Sciences
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  3. Artikel ; Online: The Structure of Monitoring Node and Monitoring Center of Environmental Monitoring System

    Li Yijie

    E3S Web of Conferences, Vol 245, p

    2021  Band 02015

    Abstract: The monitoring items shall be determined in a scientific and reasonable way according to the environmental monitoring standards and specifications, The purpose of environmental monitoring is to reflect the monitoring data of environmental monitoring ... ...

    Abstract The monitoring items shall be determined in a scientific and reasonable way according to the environmental monitoring standards and specifications, The purpose of environmental monitoring is to reflect the monitoring data of environmental monitoring system in real time, accurately and comprehensively. It provides scientific basis for environmental planning and macro decision-making. It makes the environmental monitoring system feasible and economical. Guided by the technical route of environmental monitoring, combined with the practical principle and priority monitoring principle, the comprehensive planning and reasonable arrangement are made. Environmental protection, scientific research and other purposes. Aiming at the monitoring node and monitoring center of environmental monitoring system, this paper analyzes the important position of environmental management and monitoring plan. This paper discusses the composition and structure of the monitoring system, in order to maximize the role of environmental management, reduce and mitigate the impact of monitoring projects on the ecological environment, and realize the sustainable development and operation of environmental system monitoring.
    Schlagwörter Environmental sciences ; GE1-350
    Thema/Rubrik (Code) 333 ; 710
    Sprache Englisch
    Erscheinungsdatum 2021-01-01T00:00:00Z
    Verlag EDP Sciences
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  4. Artikel ; Online: BPTF promotes glioma development through USP34-mediated de-ubiquitination of FOXC1.

    Pan, Yanling / Yuan, Feng / Lin, Zhiren / Li, Yijie

    Histology and histopathology

    2024  , Seite(n) 18748

    Abstract: Glioma is the most prevalent malignant tumor of the brain, and the study of the molecular mechanisms associated with its development has important clinical significance. Our previous study found that BPTF promotes the malignant phenotype of glioma and is ...

    Abstract Glioma is the most prevalent malignant tumor of the brain, and the study of the molecular mechanisms associated with its development has important clinical significance. Our previous study found that BPTF promotes the malignant phenotype of glioma and is significantly associated with poor prognosis; the downstream regulatory mechanisms are explored in this study. Western blot and immunohistochemical staining were used to detect protein expression in cells or tissues. BPTF knockdown as well as FOXC1-overexpressing lentiviruses were used in combination for the construction of the U251 cell model, leading to functional rescue experiments. CCK8 assay, flow cytometry, scratch assay, and Transwell assay were used to detect cell proliferation, apoptosis, and migration, respectively. Finally, immunoprecipitation assays, combined with western blot (WB), were used to detect the interaction between proteins as well as the level of ubiquitination modification. The obtained results suggested that BPTF knockdown may inhibit the malignant behavior of glioma cells by downregulating FOXC1 expression. Moreover, FOXC1 expression was significantly higher in glioma tissues than in normal brain tissues and was significantly associated with higher tumor stage and worse patient prognosis. Finally, the mechanism of FOXC1 regulation by BPTF was found to result from the affected protein stability of FOXC1 through USP34-mediated de-ubiquitylation. In conclusion, the BPTF/FOXC1 axis was identified as a key promotor in glioma development and may be a potential target in the inhibition of glioma development.
    Sprache Englisch
    Erscheinungsdatum 2024-04-15
    Erscheinungsland Spain
    Dokumenttyp Journal Article
    ZDB-ID 83911-5
    ISSN 1699-5848 ; 0213-3911
    ISSN (online) 1699-5848
    ISSN 0213-3911
    DOI 10.14670/HH-18-748
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: An 800MΩ-Input-Impedance 95.3dB-DR Δ-ΔΣ AFE for Dry-Electrode Wearable EEG Recording.

    Li, Yuying / Li, Yijie / Li, Hao / Hong, Zhiliang / Xu, Jiawei

    IEEE transactions on biomedical circuits and systems

    2024  Band PP

    Abstract: Non-invasive, closed-loop brain modulation offers an accessible and cost-effective means of evaluating and modulating one's mental and physical well-being, such as Parkinson's disease, epilepsy, and sleep disorders. However, wearable EEG systems pose ... ...

    Abstract Non-invasive, closed-loop brain modulation offers an accessible and cost-effective means of evaluating and modulating one's mental and physical well-being, such as Parkinson's disease, epilepsy, and sleep disorders. However, wearable EEG systems pose significant challenges for the analog front-end (AFE) circuits in view of μV-level EEG signals of interest, multiple sources of interference, and ill-defined skin contact. This paper presents a direct-digitization AFE tailored for dry-electrode scalp EEG recording, characterized by wide input dynamic range (DR) and high input impedance. The AFE utilizes a second-order 5-bit delta-delta sigma (Δ-ΔΣ) ADC to shape DC electrode offset (DEO) and low-frequency disturbances while retaining high accuracy. A non-inverting pseudo-differential instrumentation amplifier (IA) embedded in the ADC ensures high input impedance (Zin) and common-mode rejection ratio (CMRR). Fabricated in a standard 0.18-μm CMOS process, the AFE delivers 700-mVpp input signal range, 95.3-dB DR, 87-dB SNDR, and 800-MΩ input impedance at 50 Hz while consuming 88.4μW from a 1.2 V supply. The benefits of high DR and high input impedance have been validated by dry-electrode EEG measurement.
    Sprache Englisch
    Erscheinungsdatum 2024-03-08
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ISSN 1940-9990
    ISSN (online) 1940-9990
    DOI 10.1109/TBCAS.2024.3374891
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel: Carborane-arene fused boracyclic analogues of polycyclic aromatic hydrocarbons accessed by intramolecular borylation.

    Li, Yijie / Tamizmani, Masilamani / Akram, Manjur O / Martin, Caleb D

    Chemical science

    2024  Band 15, Heft 20, Seite(n) 7568–7575

    Abstract: Arenes are 2D aromatics while dicarbadodecaborane clusters are branded as 3D aromatic molecules. In this work we prepare molecules that feature fused 2D/3D aromatic systems that represent boron-doped analogues of polycyclic aromatic hydrocarbons. The ... ...

    Abstract Arenes are 2D aromatics while dicarbadodecaborane clusters are branded as 3D aromatic molecules. In this work we prepare molecules that feature fused 2D/3D aromatic systems that represent boron-doped analogues of polycyclic aromatic hydrocarbons. The electron withdrawing nature of the
    Sprache Englisch
    Erscheinungsdatum 2024-04-16
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 2559110-1
    ISSN 2041-6539 ; 2041-6520
    ISSN (online) 2041-6539
    ISSN 2041-6520
    DOI 10.1039/d4sc00990h
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel: [Clinical and genetic analysis of a child with Cerebral creatine deficiency syndrome due to variant of SLC6A8 gene].

    Zhang, Yunjiang / Ding, Yifeng / Li, Yijie / Zhou, Shuizhen

    Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics

    2023  Band 40, Heft 11, Seite(n) 1397–1403

    Abstract: Objective: To explore the clinical features and genetic variant in a child with Cerebral creatine deficiency syndrome (CCDS).: Methods: A child who had presented at the Affiliated Children's Hospital of Fudan University on March 5, 2021 was selected ... ...

    Abstract Objective: To explore the clinical features and genetic variant in a child with Cerebral creatine deficiency syndrome (CCDS).
    Methods: A child who had presented at the Affiliated Children's Hospital of Fudan University on March 5, 2021 was selected as the study subject. Whole exome sequencing (WES) was carried out for the child, and candidate variant was verified by Sanger sequencing. The level of creatine in the brain was determined by magnetic resonance spectroscopy.
    Results: The patient, a 1-year-and-10-month male, had presented with developmental delay and epilepsy. Both his mother and grandmother had a history of convulsions. MRS showed reduced cerebral creatine in bilateral basal ganglia and thalamus. The child was found to harbor a hemizygous splicing variant of the SLC6A8 gene, namely c.1767+1_1767+2insA, which may lead to protein truncation. The variant was not found in the public databases. Both his mother and grandmother were heterozygous carriers for the same variant.
    Conclusion: The hemizygous c.1767+1_1767+2insA variant of the SLC6A8 gene probably underlay the CCDS in this child. Discovery of the novel variant has also expanded the mutational spectrum of the SLC6A8 gene.
    Mesh-Begriff(e) Humans ; Male ; Amino Acid Metabolism, Inborn Errors ; Brain ; Creatine/genetics ; Heterozygote ; Mothers ; Nerve Tissue Proteins ; Plasma Membrane Neurotransmitter Transport Proteins/genetics ; Infant
    Chemische Substanzen Creatine (MU72812GK0) ; Nerve Tissue Proteins ; Plasma Membrane Neurotransmitter Transport Proteins ; SLC6A8 protein, human
    Sprache Chinesisch
    Erscheinungsdatum 2023-10-31
    Erscheinungsland China
    Dokumenttyp Case Reports ; English Abstract ; Journal Article
    ISSN 1003-9406
    ISSN 1003-9406
    DOI 10.3760/cma.j.cn511374-20211025-00847
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel ; Online: A 107.6 dB-DR Three-Step Incremental ADC for Motion-Tolerate Biopotential Signals Recording.

    Fang, Lairong / Zhang, Shuwen / Li, Yijie / Wu, Shunmin / Zeng, Xiaoyang / Hong, Zhiliang / Xu, Jiawei

    IEEE transactions on biomedical circuits and systems

    2024  Band 18, Heft 1, Seite(n) 111–122

    Abstract: This article describes a power-efficient, high dynamic range (DR) incremental ADC (IADC) for wearable biopotential signals recording, where DC and low-frequency disturbances such as electrode offset, 50/60 Hz interference and motion artifact must be ... ...

    Abstract This article describes a power-efficient, high dynamic range (DR) incremental ADC (IADC) for wearable biopotential signals recording, where DC and low-frequency disturbances such as electrode offset, 50/60 Hz interference and motion artifact must be tolerated. To achieve a wide DR, the IADC performs a three-step conversion by combining zoom-SAR and extended counting (EC) on top of a second-order incremental delta-sigma modulator (ΔΣM). The hybrid architecture notably reduces the oversampling ratio (OSR) with respect to conventional incremental ΔΣMs, while using the EC further improves the Signal-to-Noise-and-Distortion Ratio (SNDR) by 7.4 to 25.6 dB. Fabricated in a 0.18-μm CMOS technology, the IADC achieves 107.6-dB DR, 104.9-dB peak SNR, and 99.3-dB peak SNDR at 2 kS/s while dissipating 130 μW from 1.8-V (analog) / 1.2-V (digital) supply. This translates to a highly competitive FoM
    Mesh-Begriff(e) Equipment Design ; Signal Processing, Computer-Assisted ; Electrocardiography ; Amplifiers, Electronic ; Motion
    Sprache Englisch
    Erscheinungsdatum 2024-01-26
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ISSN 1940-9990
    ISSN (online) 1940-9990
    DOI 10.1109/TBCAS.2023.3312976
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel ; Online: The use of supramolecular systems in biomedical applications for antimicrobial properties, biocompatibility, and drug delivery.

    Li, Yijie / Vrana, Nihal Engin / Letellier, Baptiste / Lavalle, Philippe / Guilbaud-Chéreau, Chloé

    Biomedical materials (Bristol, England)

    2024  

    Abstract: Supramolecular chemistry is versatile for developing stimuli-responsive, dynamic and multifunctional structures. In the context of biomedical engineering applications, supramolecular assemblies are particularly useful as coatings for they can closely ... ...

    Abstract Supramolecular chemistry is versatile for developing stimuli-responsive, dynamic and multifunctional structures. In the context of biomedical engineering applications, supramolecular assemblies are particularly useful as coatings for they can closely mimic the natural structure and organisation of the extracellular matrix (ECM), they can also fabricate other complex systems like drug delivery systems and bioinks. In the current context of growing medical device-associated complications and the developments in the controlled drug delivery and regenerative medicine fields,supramolecular assemblies are becoming an indispensable part of the biomedical engineering arsenal. This review covers the different supramolecular assemblies in different biomedical applications with a specific focus on antimicrobial coatings, coatings that enhance biocompatibility, surface modifications on implantable medical devices, systems that promote therapeutic efficiency in cancer therapy, and the development in bioinks. The introduced supramolecularsystems include multilayer coating by polyelectrolytes, polymers incorporated with nanoparticles, coating simulation of ECM, and drug delivery systems. A perspective on the application of supramolecular systems is also included.
    Sprache Englisch
    Erscheinungsdatum 2024-05-10
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 2265222-X
    ISSN 1748-605X ; 1748-6041
    ISSN (online) 1748-605X
    ISSN 1748-6041
    DOI 10.1088/1748-605X/ad49f4
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6626: Hefte anzeigen Standort:
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  10. Artikel: Genome-Wide Identification and Analysis of Cell Cycle Genes in Birch

    Li, Yijie / Chen, Song / Liu, Yuhang / Huang, Haijiao

    Forests. 2022 Jan. 14, v. 13, no. 1

    2022  

    Abstract: Research Highlights: This study identified the cell cycle genes in birch that likely play important roles during the plant’s growth and development. This analysis provides a basis for understanding the regulatory mechanism of various cell cycles in ... ...

    Abstract Research Highlights: This study identified the cell cycle genes in birch that likely play important roles during the plant’s growth and development. This analysis provides a basis for understanding the regulatory mechanism of various cell cycles in Betula pendula Roth. Background and Objectives: The cell cycle factors not only influence cell cycles progression together, but also regulate accretion, division, and differentiation of cells, and then regulate growth and development of the plant. In this study, we identified the putative cell cycle genes in the B. pendula genome, based on the annotated cell cycle genes in Arabidopsis thaliana (L.) Heynh. It can be used as a basis for further functional research. Materials and Methods: RNA-seq technology was used to determine the transcription abundance of all cell cycle genes in xylem, roots, leaves, and floral tissues. Results: We identified 59 cell cycle gene models in the genome of B. pendula, with 17 highly expression genes among them. These genes were BpCDKA.1, BpCDKB1.1, BpCDKB2.1, BpCKS1.2, BpCYCB1.1, BpCYCB1.2, BpCYCB2.1, BpCYCD3.1, BpCYCD3.5, BpDEL1, BpDpa2, BpE2Fa, BpE2Fb, BpKRP1, BpKRP2, BpRb1, and BpWEE1. Conclusions: By combining phylogenetic analysis and tissue-specific expression data, we identified 17 core cell cycle genes in the Betulapendula genome.
    Schlagwörter Arabidopsis thaliana ; Betula pendula ; cell cycle ; genes ; growth and development ; phylogeny ; sequence analysis ; xylem
    Sprache Englisch
    Erscheinungsverlauf 2022-0114
    Erscheinungsort Multidisciplinary Digital Publishing Institute
    Dokumenttyp Artikel
    ZDB-ID 2527081-3
    ISSN 1999-4907
    ISSN 1999-4907
    DOI 10.3390/f13010120
    Datenquelle NAL Katalog (AGRICOLA)

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