Artikel ; Online: Sarcomes utérins du stroma de haut grade et sarcomes indifférenciés – Référentiels de prise en charge du Groupe Sarcome Français et du Groupe des Tumeurs Rares Gynécologiques.
2023 Band 110, Heft 7-8, Seite(n) 855–864
Abstract: High-grade endometrial stromal sarcoma (HGESS) and uterine undifferentiated sarcoma (UUS) are rare uterine malignancies arising from mesenchymal endometrial cells. They are characterized by aggressive behavior and poor prognosis. Median age of diagnostic ...
Titelübersetzung | Uterin sarcoma, high-grade stroma, indifferenciated, referential. |
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Abstract | High-grade endometrial stromal sarcoma (HGESS) and uterine undifferentiated sarcoma (UUS) are rare uterine malignancies arising from mesenchymal endometrial cells. They are characterized by aggressive behavior and poor prognosis. Median age of diagnostic is 55years. The most common symptoms are vaginal bleeding, abdominal pain, and pelvic mass. Approximately 65 % are diagnosed witch advance disease stage III or IV according to the International Federation of Gynecology and Obstetrics classification. Median overall survival is around 20months. The management of the disease must be discussed in multidisciplinary staff meetings. The standard management of HGESS and UUS is total hysterectomy with bilateral oophorectomy. Systematic lymphadenectomy is not recommended. Adjuvant therapies, such as chemotherapy and radiotherapy must be discussed. In case of oligo-metastasic disease, surgery of the primary tumor and metastasis must be discussed and if not operable the standard management is doxorubine-based chemotherapy. |
Mesh-Begriff(e) | Female ; Humans ; Middle Aged ; Uterine Neoplasms/surgery ; Sarcoma/surgery ; Combined Modality Therapy ; Hysterectomy ; Ovariectomy ; Endometrial Neoplasms/therapy ; Endometrial Neoplasms/pathology ; Neoplasm Staging |
Sprache | Französisch |
Erscheinungsdatum | 2023-04-14 |
Erscheinungsland | France |
Dokumenttyp | English Abstract ; Practice Guideline |
ZDB-ID | 213270-9 |
ISSN | 1769-6917 ; 0007-4551 |
ISSN (online) | 1769-6917 |
ISSN | 0007-4551 |
DOI | 10.1016/j.bulcan.2023.03.017 |
Datenquelle | MEDical Literature Analysis and Retrieval System OnLINE |
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