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  1. Artikel: The social dynamics of COVID-19.

    Lux, Thomas

    Physica A

    2021  Band 567, Seite(n) 125710

    Abstract: We add a simple dynamic process for adaptive "social distancing" measures to a standard SIR model of the COVID pandemic. With a limited attention span and in the absence of a consistent long-term strategy against the pandemic, this process leads to a ... ...

    Abstract We add a simple dynamic process for adaptive "social distancing" measures to a standard SIR model of the COVID pandemic. With a limited attention span and in the absence of a consistent long-term strategy against the pandemic, this process leads to a sweeping of an instability, i.e. fluctuations in the effective reproduction number around its bifurcation value of
    Sprache Englisch
    Erscheinungsdatum 2021-01-02
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article
    ZDB-ID 1466577-3
    ISSN 1873-2119 ; 0378-4371
    ISSN (online) 1873-2119
    ISSN 0378-4371
    DOI 10.1016/j.physa.2020.125710
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Konferenzbeitrag: Erfolgsfaktoren für die Einführung eines Clinical Trial Management System (CTMS)in der klinischen Forschung

    Lux, Thomas

    2021  , Seite(n) Abstr. 189

    Veranstaltung/Kongress 66. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie e. V. (GMDS), 12. Jahreskongress der Technologie- und Methodenplattform für die vernetzte medizinische Forschung e.V. (TMF); sine loco [digital]; Deutsche Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie; 2021
    Schlagwörter Medizin, Gesundheit ; Clinical Trial Management System ; Success Factors ; Health Information System
    Erscheinungsdatum 2021-09-24
    Verlag German Medical Science GMS Publishing House; Düsseldorf
    Dokumenttyp Konferenzbeitrag
    DOI 10.3205/21gmds133
    Datenquelle German Medical Science

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  3. Konferenzbeitrag: Erfolgsfaktoren von mHealth-Startups – explorative Ableitung und qualitative Analyse

    Lux, Thomas

    2021  , Seite(n) Abstr. 180

    Veranstaltung/Kongress 66. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie e. V. (GMDS), 12. Jahreskongress der Technologie- und Methodenplattform für die vernetzte medizinische Forschung e.V. (TMF); sine loco [digital]; Deutsche Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie; 2021
    Schlagwörter Medizin, Gesundheit ; mHealth ; eHealth ; Erfolgsfaktoren
    Erscheinungsdatum 2021-09-24
    Verlag German Medical Science GMS Publishing House; Düsseldorf
    Dokumenttyp Konferenzbeitrag
    DOI 10.3205/21gmds022
    Datenquelle German Medical Science

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  4. Artikel ; Online: Introgressions lead to reference bias in wheat RNA-seq analysis.

    Coombes, Benedict / Lux, Thomas / Akhunov, Eduard / Hall, Anthony

    BMC biology

    2024  Band 22, Heft 1, Seite(n) 56

    Abstract: Background: RNA-seq is a fundamental technique in genomics, yet reference bias, where transcripts derived from non-reference alleles are quantified less accurately, can undermine the accuracy of RNA-seq quantification and thus the conclusions made ... ...

    Abstract Background: RNA-seq is a fundamental technique in genomics, yet reference bias, where transcripts derived from non-reference alleles are quantified less accurately, can undermine the accuracy of RNA-seq quantification and thus the conclusions made downstream. Reference bias in RNA-seq analysis has yet to be explored in complex polyploid genomes despite evidence that they are often a complex mosaic of wild relative introgressions, which introduce blocks of highly divergent genes.
    Results: Here we use hexaploid wheat as a model complex polyploid, using both simulated and experimental data to show that RNA-seq alignment in wheat suffers from widespread reference bias which is largely driven by divergent introgressed genes. This leads to underestimation of gene expression and incorrect assessment of homoeologue expression balance. By incorporating gene models from ten wheat genome assemblies into a pantranscriptome reference, we present a novel method to reduce reference bias, which can be readily scaled to capture more variation as new genome and transcriptome data becomes available.
    Conclusions: This study shows that the presence of introgressions can lead to reference bias in wheat RNA-seq analysis. Caution should be exercised by researchers using non-sample reference genomes for RNA-seq alignment and novel methods, such as the one presented here, should be considered.
    Mesh-Begriff(e) RNA-Seq ; Triticum/genetics ; Transcriptome ; Genomics ; Polyploidy
    Sprache Englisch
    Erscheinungsdatum 2024-03-07
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 2133020-7
    ISSN 1741-7007 ; 1741-7007
    ISSN (online) 1741-7007
    ISSN 1741-7007
    DOI 10.1186/s12915-024-01853-w
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Buch ; Dissertation / Habilitation: Tumornachsorge von Patienten mit kolorektalen Karzinomen an der Chirurgischen Universitätsklinik Heidelberg

    Lux, Thomas

    2004  

    Verfasserangabe vorgelegt von Thomas Lux
    Sprache Deutsch
    Umfang 139 Bl. : Ill., graph. Darst.
    Erscheinungsland Deutschland
    Dokumenttyp Buch ; Dissertation / Habilitation
    Dissertation / Habilitation Heidelberg, Univ.,Diss., 2004
    HBZ-ID HT014286828
    Datenquelle Katalog ZB MED Medizin, Gesundheit

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  6. Artikel ; Online: A novel range telescope concept for proton CT.

    Granado-González, M / Jesús-Valls, C / Lux, T / Price, T / Sánchez, F

    Physics in medicine and biology

    2022  Band 67, Heft 3

    Abstract: Proton beam therapy can potentially offer improved treatment for cancers of the head and neck and in paediatric patients. There has been a sharp uptake of proton beam therapy in recent years as improved delivery techniques and patient benefits are ... ...

    Abstract Proton beam therapy can potentially offer improved treatment for cancers of the head and neck and in paediatric patients. There has been a sharp uptake of proton beam therapy in recent years as improved delivery techniques and patient benefits are observed. However, treatments are currently planned using conventional x-ray CT images due to the absence of devices able to perform high quality proton computed tomography (pCT) under realistic clinical conditions. A new plastic-scintillator-based range telescope concept, named ASTRA, is proposed here to measure the proton's energy loss in a pCT system. Simulations conducted using GEANT4 yield an expected energy resolution of 0.7%. If calorimetric information is used the energy resolution could be further improved to about 0.5%. In addition, the ability of ASTRA to track multiple protons simultaneously is presented. Due to its fast components, ASTRA is expected to reach unprecedented data collection rates, similar to 10
    Mesh-Begriff(e) Child ; Data Collection ; Humans ; Image Processing, Computer-Assisted ; Monte Carlo Method ; Phantoms, Imaging ; Proton Therapy/methods ; Protons ; Telescopes ; Tomography, X-Ray Computed/methods
    Chemische Substanzen Protons
    Sprache Englisch
    Erscheinungsdatum 2022-02-03
    Erscheinungsland England
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 208857-5
    ISSN 1361-6560 ; 0031-9155
    ISSN (online) 1361-6560
    ISSN 0031-9155
    DOI 10.1088/1361-6560/ac4b39
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel ; Konferenzbeitrag: IMPROVING USABILITY OF AI SYSTEMS FOR POLYP DETECTION BY RECOGNIZING DIFFERENT INTERVENTIONS DURING COLONOSCOPY

    Lux, T. / Troya, J. / Brand, M. / Meining, A. / Hann, A.

    Endoscopy

    2022  Band 54, Heft S 01

    Veranstaltung/Kongress ESGE Days 2022, Prague, Czech Republic, 2022-04-28
    Sprache Englisch
    Erscheinungsdatum 2022-04-01
    Verlag Georg Thieme Verlag KG
    Erscheinungsort Stuttgart ; New York
    Dokumenttyp Artikel ; Konferenzbeitrag
    ZDB-ID 80120-3
    ISSN 1438-8812 ; 0013-726X
    ISSN (online) 1438-8812
    ISSN 0013-726X
    DOI 10.1055/s-0042-1745072
    Datenquelle Thieme Verlag

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  8. Buch ; Dissertation / Habilitation: Gespräche mit afrikanischen Krankenpflegern und Heilern

    Lux, Thomas

    Bilder von Krankheit im Mikrokosmos von Malanville (Benin)

    (Medizin in Entwicklungsländern ; 30)

    1991  

    Serientitel Medizin in Entwicklungsländern ; 30
    Überordnung
    Schlagwörter Medicine, Traditional / Benin ; Attitude to Health / ethnology / Benin ; Nurses / Benin ; Malanville ; Volksmedizin ; Primäre Gesundheitsversorgung ; Kulturvergleich
    Schlagwörter Interkultureller Vergleich ; Cross-cultural Analysis ; Medizinische Grundversorgung ; Primärmedizin ; Basisgesundheitsversorgung ; Primary care ; Primary health care ; Health care marketing ; Volksheilkunde ; Volkstümliche Medizin
    Sprache Deutsch
    Umfang IX, 312 S. : Ill., Kt.
    Verlag Lang
    Erscheinungsort Frankfurt am Main u.a.
    Erscheinungsland Deutschland
    Dokumenttyp Buch ; Dissertation / Habilitation
    Dissertation / Habilitation Heidelberg, Univ., Diss., 1990
    HBZ-ID HT003964570
    ISBN 3-631-43760-9 ; 978-3-631-43760-5
    Datenquelle Katalog ZB MED Medizin, Gesundheit

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  9. Buch ; Dissertation / Habilitation: Gespräche mit afrikanischen Krankenpflegern und Heilern

    Lux, Thomas

    Bilder von Krankheit im Mikrokosmos von Malanville

    1990  

    Verfasserangabe vorgelegt von Thomas Lux
    Schlagwörter Medicine, Traditional / Benin ; Primary Health Care ; Health Services, Indigenous / Benin ; Cross-Cultural Comparison ; Cultural Characteristics ; Attitude to Health
    Sprache Deutsch
    Umfang IX, 299 S. : Ill., Kt.
    Dokumenttyp Buch ; Dissertation / Habilitation
    Dissertation / Habilitation Heidelberg, Univ., Diss., 1990
    HBZ-ID HT003842555
    Datenquelle Katalog ZB MED Medizin, Gesundheit

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  10. Buch ; Online: On the distribution of links in financial networks

    Lux, Thomas

    structural heterogeneity and functional form

    (Economics working paper / Christian-Albrechts-Universität Kiel, Department of Economics ; no 2017, 05)

    2017  

    Abstract: We investigate the distribution of links in three large data-sets, one of these covering interbank loans in the electronic trading platform e-MID, the other two covering a large part of the loans of banks to non-financial companies in the Spanish and ... ...

    Verfasserangabe by Thomas Lux
    Serientitel Economics working paper / Christian-Albrechts-Universität Kiel, Department of Economics ; no 2017, 05
    Abstract We investigate the distribution of links in three large data-sets, one of these covering interbank loans in the electronic trading platform e-MID, the other two covering a large part of the loans of banks to non-financial companies in the Spanish and Japanese economies, respectively. In contrast to all previous literature, we do not assume homogeneity of the link distribution over time and across different categories of agents (banks, firms) but apply our hypothesized distributions as regression models. As it turns out, many of the tested sources of heterogeneity turn out to be significant regressors. For instance, we find pervasive time heterogeneity of link formation in all three data sets, and also heterogeneity for different categories of banks/firms that can be identified in the data. Across all networks, the Negative Binominal model always outperforms all alternative models confirming its good performance as a model of economic count data in many previous applications.
    Schlagwörter Financial networks ; interbank market ; degree distribution ; credit network
    Sprache Englisch
    Umfang 1 Online-Ressource (circa 29 Seiten)
    Verlag Christian-Albrechts-Universität zu Kiel, Department of Economics
    Erscheinungsort Kiel
    Dokumenttyp Buch ; Online
    Datenquelle ECONomics Information System

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