Artikel: Restorable, high-strength poly(N-isopropylacrylamide) hydrogels constructed through chitosan-based dual macro-cross-linkers with rapid response to temperature jumps
RSC advances. 2017 Oct. 11, v. 7, no. 75
2017
Abstract: To address the poor mechanical performance of conventional thermo-responsive poly(N-isopropylacrylamide) (pNIPAM) hydrogels, methacryloyl covalently-modified chitosan (methacryloylchitosan, MACS) was conceived as the chemical macro-cross-linker and ... ...
| Abstract | To address the poor mechanical performance of conventional thermo-responsive poly(N-isopropylacrylamide) (pNIPAM) hydrogels, methacryloyl covalently-modified chitosan (methacryloylchitosan, MACS) was conceived as the chemical macro-cross-linker and employed cooperatively with chitosan, as the physical macro-cross-linker, to construct dually macro-cross-linked pNIPAM hydrogels for the first time. The employed MACS was synthesized through acylation of chitosan using methacrylic acid activated by N-(3-dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride (EDC) and N-hydroxy-succinimide (NHS). The influence of the preparation conditions, including the solids content, the dosage and component of the cross-linkers as well as the amount of the initiator, on the mechanical performance and swelling/deswelling properties of the obtained hydrogels was investigated systematically. The prepared dual-cross-linked pNIPAM hydrogels exhibit high mechanical strength, manifested in the achieved compressive stress of 8.75 MPa at 98% strain and tensile strength of 0.105 MPa. The high recovery efficiency (beyond 95%) from cyclic tensile tests reveals the good recoverability of these hydrogels. Moreover, they exhibit excellent thermo-responsiveness, to be more specific, rapid deswelling rates, i.e., most can release 50% of the absorbed water in ∼10 minutes on the temperature jump across the phase transition temperature. In particular, the deswelling rate increases with the increase of either the cross-linkers or MACS. The prominent mechanical performance and rapid responsiveness of the novel pNIPAM hydrogels is highly conductive for their future applications. |
|---|---|
| Schlagwörter | acylation ; chitosan ; hydrogels ; phase transition ; temperature ; tensile strength |
| Sprache | Englisch |
| Erscheinungsverlauf | 2017-1011 |
| Umfang | p. 47767-47774. |
| Erscheinungsort | The Royal Society of Chemistry |
| Dokumenttyp | Artikel |
| ISSN | 2046-2069 |
| DOI | 10.1039/c7ra10148a |
| Datenquelle | NAL Katalog (AGRICOLA) |
Zusatzmaterialien
Kategorien
Über subito bestellen
Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.
Fernleihe an ZB MED
Sie können sich den gewünschten Titel als lokale Nutzerin oder lokaler Nutzer von ZB MED direkt an den Standort Köln schicken lassen.