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  1. Artikel ; Online: Disseminated intravascular coagulation in perinatal medicine

    M. A. Mingalimov / K. N. Grigorieva / M. V. Tretyakova / I. Elalamy / Kh. G. Sultangadzhieva / V. O. Bitsadze / J. Kh. Khizroeva / A. D. Makatsariya

    Акушерство, гинекология и репродукция, Vol 14, Iss 1, Pp 56-

    2020  Band 68

    Abstract: Introduction. Disseminated intravascular coagulation (DIC) is an acquired syndrome characterized by intravascular activation of blood clotting without specific localization and arising from various causes. DIC is the most complex and high-priority ... ...

    Abstract Introduction. Disseminated intravascular coagulation (DIC) is an acquired syndrome characterized by intravascular activation of blood clotting without specific localization and arising from various causes. DIC is the most complex and high-priority problem in contemporary clinical medicine including obstetrics and perinatology. DIC significance is related to its peak perinatal mortality, as well as a large rate of complications during childbirth and postpartum period.Aim: to conduct comprehensive data assessment related to DIC pathogenesis and management in pregnant women and newborns.Materials and methods. A search for DIC-related publications within the past 10 years was conducted in international research databases: Scientific Electronic Library Online eLibrary, Google Scholar, ScienceDirect, Cochrane Library, PubMed/Medline. The data regarding DIC diagnostic criteria and markers, as well as current approach to its treatment are presented.Results. DIC may be considered as one of the causes resulting in massive obstetric bleeding. The majority of pregnancy-related complications is manifested as preeclampsia, premature detachment of normally situated placenta and anaphylactoid syndrome of pregnancy. Any massive bleeding should be perceived as hemorrhage resulting from the DIC progression.Conclusion. Knowledge of the DIC pathogenetic mechanisms is necessary for conducting a differential diagnosis and applying timely treatment.
    Schlagwörter disseminated intravascular coagulation ; dic ; perinatal medicine ; thromboses ; hemostatic disorders ; anticoagulant therapy ; gestation ; neonatal thromboses ; Gynecology and obstetrics ; RG1-991
    Thema/Rubrik (Code) 610
    Sprache Russisch
    Erscheinungsdatum 2020-04-01T00:00:00Z
    Verlag IRBIS LLC
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  2. Artikel ; Online: Coronavirus disease (COVID-19) and disseminated intravascular coagulation syndrome

    A. D. Makatsariya / K. N. Grigoreva / M. A. Mingalimov / V. O. Bitsadze / J. Kh. Khizroeva / M. V. Tretyakova / I. Elalamy / A. S. Shkoda / V. B. Nemirovskiy / D. V. Blinov / D. V. Mitryuk

    Акушерство, гинекология и репродукция, Vol 0, Iss

    2020  

    Abstract: COVID-19 is an infectious disease caused by the beta coronavirus SARS-CoV-2, which became widespread worldwide in 2020. In most severe patients, the clinical picture begins with respiratory failure, then progressing to polyorgan failure. The most adverse ...

    Abstract COVID-19 is an infectious disease caused by the beta coronavirus SARS-CoV-2, which became widespread worldwide in 2020. In most severe patients, the clinical picture begins with respiratory failure, then progressing to polyorgan failure. The most adverse prognostic sign is the development of coagulopathy. Based on the analysis of clinical data available to date, 71.4% of those who died and 0.6% of those who survived showed signs of explicit disseminated intravascular coagulation syndrome (DIC-syndrome). Monitoring of D-dimer, prothrombin time (PT), platelet and fibrinogen count are important for determining treatment and indications for hospitalization among patients with COVID-19. If these parameters deteriorate, more "aggressive" intensive care should be performed. Lowmolecular weight heparin (LMWH) should be administered to all patients with diagnosed COVID-19 infection (including non-critical patients) who require hospitalization if these patients have no contraindications for LMWH.
    Schlagwörter sars-cov-2 ; covid-19 ; coronavirus ; disseminated intravascular coagulation syndrome ; dicsyndrome ; anticoagulant therapy ; low molecular weight heparin ; lmwh ; Gynecology and obstetrics ; RG1-991 ; covid19
    Thema/Rubrik (Code) 610
    Sprache Russisch
    Erscheinungsdatum 2020-04-01T00:00:00Z
    Verlag IRBIS LLC
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

    Volltext online

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    Fernleihe an ZB MED

    Sie können sich den gewünschten Titel als lokale Nutzerin oder lokaler Nutzer von ZB MED direkt an den Standort Köln schicken lassen.

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