LIVIVO - Das Suchportal für Lebenswissenschaften

switch to English language
Erweiterte Suche

Suchergebnis

Treffer 1 - 5 von insgesamt 5

Suchoptionen

  1. Artikel ; Online: In Silico Investigation of Potential Applications of Gamma Carbonic Anhydrases as Catalysts of CO

    Manyumwa, Colleen Varaidzo / Bishop, Özlem Tastan

    International journal of molecular sciences

    2021  Band 22, Heft 6

    Abstract: Carbonic anhydrases (CAs) have been identified as ideal catalysts for ... ...

    Abstract Carbonic anhydrases (CAs) have been identified as ideal catalysts for CO
    Mesh-Begriff(e) Amino Acid Sequence ; Bacteria/enzymology ; Bacterial Proteins/chemistry ; Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Biomineralization ; Carbon Dioxide/chemistry ; Carbon Dioxide/metabolism ; Carbonic Anhydrases/chemistry ; Carbonic Anhydrases/genetics ; Carbonic Anhydrases/metabolism ; Catalysis ; Catalytic Domain ; Computer Simulation ; Hot Springs/microbiology ; Hydrothermal Vents/microbiology ; Molecular Dynamics Simulation ; Protein Conformation ; Sequence Homology, Amino Acid ; Temperature ; Thermus thermophilus/enzymology
    Chemische Substanzen Bacterial Proteins ; Carbon Dioxide (142M471B3J) ; Carbonic Anhydrases (EC 4.2.1.1)
    Sprache Englisch
    Erscheinungsdatum 2021-03-11
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms22062861
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

  2. Artikel ; Online: Genome Study of α-, β-, and γ-Carbonic Anhydrases from the Thermophilic Microbiome of Marine Hydrothermal Vent Ecosystems

    Gheibzadeh, Mohammad Sadegh / Manyumwa, Colleen Varaidzo / Tastan Bishop, Özlem / Shahbani Zahiri, Hossein / Parkkila, Seppo / Zolfaghari Emameh, Reza

    Biology (Basel). 2023 May 25, v. 12, no. 6

    2023  

    Abstract: Carbonic anhydrases (CAs) are metalloenzymes that can help organisms survive in hydrothermal vents by hydrating carbon dioxide (CO₂). In this study, we focus on alpha (α), beta (β), and gamma (γ) CAs, which are present in the thermophilic microbiome of ... ...

    Abstract Carbonic anhydrases (CAs) are metalloenzymes that can help organisms survive in hydrothermal vents by hydrating carbon dioxide (CO₂). In this study, we focus on alpha (α), beta (β), and gamma (γ) CAs, which are present in the thermophilic microbiome of marine hydrothermal vents. The coding genes of these enzymes can be transferred between hydrothermal-vent organisms via horizontal gene transfer (HGT), which is an important tool in natural biodiversity. We performed big data mining and bioinformatics studies on α-, β-, and γ-CA coding genes from the thermophilic microbiome of marine hydrothermal vents. The results showed a reasonable association between thermostable α-, β-, and γ-CAs in the microbial population of the hydrothermal vents. This relationship could be due to HGT. We found evidence of HGT of α- and β-CAs between Cycloclasticus sp., a symbiont of Bathymodiolus heckerae, and an endosymbiont of Riftia pachyptila via Integrons. Conversely, HGT of β-CA genes from the endosymbiont Tevnia jerichonana to the endosymbiont Riftia pachyptila was detected. In addition, Hydrogenovibrio crunogenus SP-41 contains a β-CA gene on genomic islands (GIs). This gene can be transferred by HGT to Hydrogenovibrio sp. MA2-6, a methanotrophic endosymbiont of Bathymodiolus azoricus, and a methanotrophic endosymbiont of Bathymodiolus puteoserpentis. The endosymbiont of R. pachyptila has a γ-CA gene in the genome. If α- and β-CA coding genes have been derived from other microorganisms, such as endosymbionts of T. jerichonana and Cycloclasticus sp. as the endosymbiont of B. heckerae, through HGT, the theory of the necessity of thermostable CA enzymes for survival in the extreme ecosystem of hydrothermal vents is suggested and helps the conservation of microbiome natural diversity in hydrothermal vents. These harsh ecosystems, with their integral players, such as HGT and endosymbionts, significantly impact the enrichment of life on Earth and the carbon cycle in the ocean.
    Schlagwörter Cycloclasticus ; Hydrogenovibrio ; biodiversity ; bioinformatics ; carbon cycle ; carbon dioxide ; carbonate dehydratase ; ecosystems ; endosymbionts ; genes ; genomics ; horizontal gene transfer ; methanotrophs ; microbiome ; thermal stability
    Sprache Englisch
    Erscheinungsverlauf 2023-0525
    Erscheinungsort Multidisciplinary Digital Publishing Institute
    Dokumenttyp Artikel ; Online
    ZDB-ID 2661517-4
    ISSN 2079-7737
    ISSN 2079-7737
    DOI 10.3390/biology12060770
    Datenquelle NAL Katalog (AGRICOLA)

    Zusatzmaterialien

    Kategorien

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

  3. Artikel ; Online: Alpha-Carbonic Anhydrases from Hydrothermal Vent Sources as Potential Carbon Dioxide Sequestration Agents:

    Manyumwa, Colleen Varaidzo / Emameh, Reza Zolfaghari / Tastan Bishop, Özlem

    International journal of molecular sciences

    2020  Band 21, Heft 21

    Abstract: With the increase in ... ...

    Abstract With the increase in CO
    Mesh-Begriff(e) Amino Acid Sequence ; Bacteria/enzymology ; Bacterial Proteins/metabolism ; Carbon Dioxide/isolation & purification ; Carbon Dioxide/metabolism ; Carbonic Anhydrases/chemistry ; Carbonic Anhydrases/metabolism ; Computer Simulation ; Hydrothermal Vents/microbiology ; Molecular Dynamics Simulation ; Sequence Homology ; Sequestering Agents/metabolism
    Chemische Substanzen Bacterial Proteins ; Sequestering Agents ; Carbon Dioxide (142M471B3J) ; Carbonic Anhydrases (EC 4.2.1.1)
    Schlagwörter covid19
    Sprache Englisch
    Erscheinungsdatum 2020-10-29
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms21218066
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

  4. Artikel: Genome Study of α-, β-, and γ-Carbonic Anhydrases from the Thermophilic Microbiome of Marine Hydrothermal Vent Ecosystems.

    Gheibzadeh, Mohammad Sadegh / Manyumwa, Colleen Varaidzo / Tastan Bishop, Özlem / Shahbani Zahiri, Hossein / Parkkila, Seppo / Zolfaghari Emameh, Reza

    Biology

    2023  Band 12, Heft 6

    Abstract: Carbonic anhydrases (CAs) are metalloenzymes that can help organisms survive in hydrothermal vents by hydrating carbon dioxide ( ... ...

    Abstract Carbonic anhydrases (CAs) are metalloenzymes that can help organisms survive in hydrothermal vents by hydrating carbon dioxide (CO
    Sprache Englisch
    Erscheinungsdatum 2023-05-25
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2661517-4
    ISSN 2079-7737
    ISSN 2079-7737
    DOI 10.3390/biology12060770
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

  5. Artikel ; Online: Decoding the Molecular Effects of Atovaquone Linked Resistant Mutations on

    Chebon-Bore, Lorna / Sanyanga, Taremekedzwa Allan / Manyumwa, Colleen Varaidzo / Khairallah, Afrah / Tastan Bishop, Özlem

    International journal of molecular sciences

    2021  Band 22, Heft 4

    Abstract: Atovaquone (ATQ) is a drug used to prevent and treat malaria that functions by targeting ... ...

    Abstract Atovaquone (ATQ) is a drug used to prevent and treat malaria that functions by targeting the
    Mesh-Begriff(e) Animals ; Atovaquone/chemistry ; Atovaquone/pharmacology ; Catalytic Domain ; Cattle ; Cytochromes b/genetics ; Drug Resistance/drug effects ; Drug Resistance/genetics ; Entropy ; Iron-Sulfur Proteins/genetics ; Iron-Sulfur Proteins/metabolism ; Ligands ; Lipid Bilayers/metabolism ; Models, Molecular ; Molecular Docking Simulation ; Molecular Dynamics Simulation ; Mutation/genetics ; Phospholipids/metabolism ; Plasmodium falciparum/drug effects ; Plasmodium falciparum/genetics ; Protein Conformation ; Protein Interaction Maps ; Protein Stability
    Chemische Substanzen Iron-Sulfur Proteins ; Ligands ; Lipid Bilayers ; Phospholipids ; Cytochromes b (9035-37-4) ; Atovaquone (Y883P1Z2LT)
    Sprache Englisch
    Erscheinungsdatum 2021-02-21
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms22042138
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

Zum Seitenanfang