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  1. Article: Cardiac resynchronization therapy with conduction system pacing in a long-term heart transplant recipient: A case report.

    Taddeucci, Simone / Marallo, Carmine / Merello, Giacomo / Santoro, Amato

    Indian pacing and electrophysiology journal

    2024  Volume 24, Issue 3, Page(s) 147–149

    Abstract: We performed cardiac resynchronization therapy by means of conduction system pacing in a heart transplant patient suffering from heart failure with reduced ejection fraction and atrial fibrillation with conduction disturbance (bifascicular block and QRS > ...

    Abstract We performed cardiac resynchronization therapy by means of conduction system pacing in a heart transplant patient suffering from heart failure with reduced ejection fraction and atrial fibrillation with conduction disturbance (bifascicular block and QRS >160 ms). ECG monitoring showed paroxysmal atrioventricular block. Biventricular pacing was not feasible due to the absence of a suitable coronary sinus branch for pacing. His bundle pacing was performed, and an implantable cardioverter-defibrillator was implanted due to severe left ventricular dysfunction. Cardiac allograft vasculopathy was excluded. During follow-up, the patient's left ventricular function improved, and symptoms alleviated with a high percentage of ventricular stimulation.
    Language English
    Publishing date 2024-01-09
    Publishing country Netherlands
    Document type Case Reports
    ZDB-ID 2123606-9
    ISSN 0972-6292
    ISSN 0972-6292
    DOI 10.1016/j.ipej.2024.01.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: The interventricular conduction delays guide best cardiac resynchronization therapy: A tailored-patient approach to perform a CRT through Conduction System Pacing.

    Santoro, Amato / Barilli, Maria / Marallo, Carmine / Baiocchi, Claudia

    Indian pacing and electrophysiology journal

    2023  Volume 24, Issue 1, Page(s) 42–44

    Abstract: Evaluation of conduction intervals to predict success of resynchronization in biventricular pacing(BiVP) or Conduction System Pacing(CSP) is not spread in clinical practice. A right ventricle-to-left ventricle intrinsic conduction interval (RVs-LVs) > 70  ...

    Abstract Evaluation of conduction intervals to predict success of resynchronization in biventricular pacing(BiVP) or Conduction System Pacing(CSP) is not spread in clinical practice. A right ventricle-to-left ventricle intrinsic conduction interval (RVs-LVs) > 70 ms or prolonged RVpaced - LVs(RVp-LVs)interval can predict Cardiac Resynchronization Therapy (CRT)response.This paper describes a case of cardiac resynchronization guided by spontaneous and paced interventricular conduction delays (IVCD) obtained in BiVP that led to changing intraoperative approach. A strategy for cardiac resynchronization based on the CSP/BiVP approach according to the IVCD could represent a viable and reliable solution to obtain a narrow paced QRS and to improve the CRT response.
    Language English
    Publishing date 2023-11-17
    Publishing country Netherlands
    Document type Case Reports
    ZDB-ID 2123606-9
    ISSN 0972-6292
    ISSN 0972-6292
    DOI 10.1016/j.ipej.2023.11.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Moderator Band and Ventricular Tachycardia: Structural or Functional Substrate?

    Landra, Federico / Marallo, Carmine / Santoro, Amato / Taddeucci, Simone / Tavera, Maria Cristina / Baiocchi, Claudia / Palazzuoli, Alberto

    Journal of cardiovascular development and disease

    2023  Volume 10, Issue 4

    Abstract: The moderator band (MB) is an intracavitary structure of the right ventricle composed of muscular fibers encompassing specialized Purkinje fibers, separated each other by collagen and adipose tissue. In the last decades, premature ventricular complexes ... ...

    Abstract The moderator band (MB) is an intracavitary structure of the right ventricle composed of muscular fibers encompassing specialized Purkinje fibers, separated each other by collagen and adipose tissue. In the last decades, premature ventricular complexes originating within the Purkinje network have been implicated in the genesis of life-threatening arrhythmias. However, right Purkinje network arrhythmias have been much less reported in the literature compared to the left counterpart. The MB has unique anatomical and electrophysiological properties, which may account for its arrhythmogenicity and may be responsible for a significant portion of idiopathic ventricular fibrillation. MB embodies autonomic nervous system cells, with important implications in arrhythmogenesis. Some idiopathic ventricular arrhythmias, defined as the absence of any identifiable structural heart disorder, can begin from this site. Due to these complex structural and functional peculiarities strictly interplayed each other, it is arduous to determine the precise mechanism underlying MB arrhythmias. MB-related arrhythmias should be differentiated from other right Purkinje fibers arrhythmias because of the opportunity for intervention and the unusual site for the ablation poorly described in the literature. In the current paper, we report the characteristics and electrical properties of the MB, their involvement in arrhythmogenesis, clinical and electrophysiological peculiarities of MB-related arrhythmias, and current treatment options.
    Language English
    Publishing date 2023-04-06
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2777082-5
    ISSN 2308-3425 ; 2308-3425
    ISSN (online) 2308-3425
    ISSN 2308-3425
    DOI 10.3390/jcdd10040159
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Reverse Septal Movement: A Step Forward in the Comprehension of the Underlying Causes.

    Diviggiano, Enrico Emilio / Rosi, Sara / Landra, Federico / Marallo, Carmine / Scoppa, Cristina / Castellani, Debora / Mandoli, Giulia Elena / Pastore, Maria Concetta / Cavigli, Luna / D'Ascenzi, Flavio / Cameli, Matteo / Focardi, Marta

    Journal of clinical medicine

    2024  Volume 13, Issue 4

    Abstract: 1) ...

    Abstract (1)
    Language English
    Publishing date 2024-02-06
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm13040928
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Biventricular or Conduction System Pacing for Cardiac Resynchronization Therapy: A Strategy for Cardiac Resynchronization Based on a Hybrid Approach.

    Santoro, Amato / Landra, Federico / Marallo, Carmine / Taddeucci, Simone / Sisti, Nicolò / Pica, Andrea / Stefanini, Andrea / Tavera, Maria Cristina / Pagliaro, Antonio / Baiocchi, Claudia / Cameli, Matteo

    Journal of cardiovascular development and disease

    2023  Volume 10, Issue 4

    Abstract: Background: Cardiac resynchronization therapy (CRT) is usually performed with biventricular pacing (BiVP), but recently, conduction system pacing (CSP) has been proposed as an alternative in case of BiVP failure. The aim of this study is to define an ... ...

    Abstract Background: Cardiac resynchronization therapy (CRT) is usually performed with biventricular pacing (BiVP), but recently, conduction system pacing (CSP) has been proposed as an alternative in case of BiVP failure. The aim of this study is to define an algorithm to choose between BiVP and CSP resynchronization using the interventricular conduction delays (IVCD) as a guide.
    Methods: Consecutive patients from January 2018 to December 2020 with an indication for CRT were prospectively enrolled in the study group (delays-guided resynchronization group, DRG). A treatment algorithm based on IVCD was used to decide whether to leave the left ventricular (LV) lead to perform BiVP or pull it out and perform CSP. Outcomes from the DRG group were compared to a historical cohort of CRT patients who underwent CRT procedures between January 2016 and December 2017 (resynchronization standard guide group, SRG). The primary endpoint was a composite of cardiovascular mortality, heart failure (HF) hospitalization, or HF event at 1 year after the date of intervention.
    Results: The study population consisted of 292 patients, of which 160 (54.8%) were in the DRG and 132 (45.2%) in the SRG. In the DRG, 41 of 160 patients underwent CSP based on the treatment algorithm (25.6%). The primary endpoint was significantly higher in the SRG (48/132, 36.4%) compared to the DRG (35/160, 21.8%) (hazard ratio (HR): 1.72; 95% confidence interval (CI): 1.12-2.65;
    Conclusions: A treatment algorithm based on IVCD shifted one patient out of every four from BiVP to CSP, with consequent reduction in the primary endpoint after implantation. Therefore, its application could be useful to determine whether to perform BiVP or CSP.
    Language English
    Publishing date 2023-04-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2777082-5
    ISSN 2308-3425 ; 2308-3425
    ISSN (online) 2308-3425
    ISSN 2308-3425
    DOI 10.3390/jcdd10040169
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: The role of cardiac computed tomography in sports cardiology: back to the future!

    D'Ascenzi, Flavio / Baggiano, Andrea / Cavigli, Luna / Mandoli, Giulia Elena / Andreini, Daniele / Marallo, Carmine / Valente, Serafina / Focardi, Marta / Cameli, Matteo / Pontone, Gianluca

    European heart journal. Cardiovascular Imaging

    2022  Volume 23, Issue 11, Page(s) e481–e493

    Abstract: In recent years, the role of pre-participation evaluation (PPE) in the prevention of sudden cardiac death in competitive athletes has become evident. Most physicians routinely supplement assessment by resting electrocardiogram with imaging techniques, ... ...

    Abstract In recent years, the role of pre-participation evaluation (PPE) in the prevention of sudden cardiac death in competitive athletes has become evident. Most physicians routinely supplement assessment by resting electrocardiogram with imaging techniques, such as echocardiography. The primary goal of imaging in the clinical assessment of competitive athletes is to exclude cardiovascular conditions associated with adverse outcomes. Cardiac computed tomography is emerging as an important technique for stratifying cardiovascular risk and assessing coronary artery disease (CAD), particularly in master athletes. Conversely, in young athletes, this technique has the best non-invasive coronary artery resolution and provides valuable details on coronary artery anatomy. Recent technical developments have brought about a dramatic reduction in radiation exposure, a major drawback of this diagnostic method; nowadays cardiac computed tomography may be performed at a dose of barely one millisievert. The present review provides a practical guide for the use of cardiac computed tomography in the PPE of competitive athletes, with a specific focus on its value for detecting congenital coronary anomalies and CAD in young and master athletes, respectively.
    MeSH term(s) Humans ; Sports ; Death, Sudden, Cardiac/prevention & control ; Athletes ; Coronary Artery Disease/diagnostic imaging ; Echocardiography ; Cardiology ; Tomography
    Language English
    Publishing date 2022-04-18
    Publishing country England
    Document type Review ; Journal Article
    ZDB-ID 2638345-7
    ISSN 2047-2412 ; 2047-2404
    ISSN (online) 2047-2412
    ISSN 2047-2404
    DOI 10.1093/ehjci/jeac069
    Database MEDical Literature Analysis and Retrieval System OnLINE

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