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Artikel: Prostaglandin D2 synthase controls Schwann cells metabolism.

Trimarco, Amelia / Audano, Matteo / Marca, Rosa La / Cariello, Mariaconcetta / Falco, Marta / Pedretti, Silvia / Imperato, Gabriele / Cestaro, Alessandro / Podini, Paola / Dina, Giorgia / Quattrini, Angelo / Massimino, Luca / Caruso, Donatella / Mitro, Nico / Taveggia, Carla

bioRxiv : the preprint server for biology

2024  

Abstract: We previously reported that in the absence of Prostaglandin D2 synthase (L-PGDS) peripheral nerves are hypomyelinated in development and that with aging they present aberrant myelin sheaths. We now demonstrate that L-PGDS expressed in Schwann cells is ... ...

Abstract We previously reported that in the absence of Prostaglandin D2 synthase (L-PGDS) peripheral nerves are hypomyelinated in development and that with aging they present aberrant myelin sheaths. We now demonstrate that L-PGDS expressed in Schwann cells is part of a coordinated program aiming at preserving myelin integrity.
Sprache Englisch
Erscheinungsdatum 2024-03-04
Erscheinungsland United States
Dokumenttyp Preprint
DOI 10.1101/2024.02.29.582775
Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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