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  1. Article ; Online: Author's response: "Lower mean phosphate independently predicts mortality in critically ill patients: results from a prospective cohort study".

    Lima Júnior, Washington / Calderaro, Débora Cerqueira / Passos, Rogério / Côrte, Margaret / Leal, Jose Adalberto / Mayrink, Marcelo Oliveira / Ferreira, Gilda

    Journal of critical care

    2023  Volume 78, Page(s) 154374

    MeSH term(s) Humans ; Prospective Studies ; Critical Illness ; Cohort Studies ; Intensive Care Units ; Phosphates
    Chemical Substances Phosphates
    Language English
    Publishing date 2023-08-01
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 632818-0
    ISSN 1557-8615 ; 0883-9441
    ISSN (online) 1557-8615
    ISSN 0883-9441
    DOI 10.1016/j.jcrc.2023.154374
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Lower mean phosphate independently predicts mortality in critically ill patients: Results from a prospective cohort study.

    Lima, Washington / Calderaro, Débora Cerqueira / Passos, Rogério / Côrte, Margaret / Leal, Jose Adalberto / Mayrink, Marcelo Oliveira / Ferreira, Gilda

    Journal of critical care

    2023  Volume 75, Page(s) 154273

    Abstract: Purpose: To evaluate lower mean phosphate as a prognostic tool in critically ill patients.: Methods: This is a prospective single-center cohort study including adult patients (> 18 years) with a length of intensive care unit (ICU) stay of at least 24  ...

    Abstract Purpose: To evaluate lower mean phosphate as a prognostic tool in critically ill patients.
    Methods: This is a prospective single-center cohort study including adult patients (> 18 years) with a length of intensive care unit (ICU) stay of at least 24 h. Phosphatemia was evaluated within 1 h of ICU admission and once daily. Mean phosphate, calculated by the simple arithmetic mean of daily phosphate measurements, was proposed and tested. Standard severity scores were applied. Multivariate and survival analyses were performed.
    Results: A total of 317 patients were included, of whom 111 (35%) presented hypophosphatemia. Hypophosphatemia associated with surgical conditions, nutritional therapy, hypovitaminosis D, hyperparathyroidism, mechanical ventilation (need and duration), and ICU and hospital length of stay were evaluated. Admission APACHE II and SOFA (ICU days 1, 3, and 7) scores and ICU and in-hospital mortality were greater in the hypophosphatemia group than control group. Higher APACHE II (RR: 1.1; 95%CI: 1.01-1.2; p = 0.045) and lower mean phosphate (RR: 0.02; 95%CI: 0.001-0.09; p = 0.044) independently predicted ICU and in-hospital mortality.
    Conclusions: Hypophosphatemia is frequent in the ICU, and was associated with unfavorable outcomes. This study introduces the importance of longitudinal monitoring of phosphate levels, since lower mean phosphate is an independent predictor of mortality in critically ill patients.
    MeSH term(s) Adult ; Humans ; Prospective Studies ; Cohort Studies ; Intensive Care Units ; Critical Illness/therapy ; Hospital Mortality ; Hypophosphatemia ; Phosphates ; Length of Stay
    Chemical Substances Phosphates
    Language English
    Publishing date 2023-02-02
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 632818-0
    ISSN 1557-8615 ; 0883-9441
    ISSN (online) 1557-8615
    ISSN 0883-9441
    DOI 10.1016/j.jcrc.2023.154273
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Author's response: Lower mean phosphate independently predicts mortality in critically ill patients: Results from a prospective cohort study.

    Lima Júnior, Washington / Calderaro, Débora Cerqueira / Passos, Rogério / Côrte, Margaret / Leal, Jose Adalberto / Mayrink, Marcelo Oliveira / Ferreira, Gilda

    Journal of critical care

    2023  Volume 76, Page(s) 154311

    MeSH term(s) Humans ; Prospective Studies ; Critical Illness ; Cohort Studies ; Intensive Care Units ; Phosphates
    Chemical Substances Phosphates
    Language English
    Publishing date 2023-05-03
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 632818-0
    ISSN 1557-8615 ; 0883-9441
    ISSN (online) 1557-8615
    ISSN 0883-9441
    DOI 10.1016/j.jcrc.2023.154311
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

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