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  1. Artikel ; Online: Optimizing electrical impedance myography of the tongue in amyotrophic lateral sclerosis.

    Mcilduff, Courtney E / Yim, Sung J / Pacheck, Adam K / Rutkove, Seward B

    Muscle & nerve

    2017  Band 55, Heft 4, Seite(n) 539–543

    Abstract: Introduction: Electrical impedance myography (EIM) can quantify muscle health at a range of frequencies, including that most commonly employed, 50 kHz. However, disease-related changes in EIM data suggest the distinction between normal and patient EIM ... ...

    Abstract Introduction: Electrical impedance myography (EIM) can quantify muscle health at a range of frequencies, including that most commonly employed, 50 kHz. However, disease-related changes in EIM data suggest the distinction between normal and patient EIM values could be more apparent at frequencies of >50 kHz. We investigated at what other selected frequencies tongue EIM may differentiate healthy individuals and amyotrophic lateral sclerosis (ALS) patients, remain reliable, and correlate with a standard metric of bulbar function.
    Methods: Tongue EIM phase data from 30 volunteers and 11 ALS patients were analyzed at 6 discrete frequencies from 50 to 500 kHz.
    Results: Of the frequencies assessed, EIM demonstrated maximal separation and reliability at 100 kHz, where phase value was also significantly correlated with the bulbar subscore on the revised version of the ALS Functional Rating Scale.
    Conclusions: One hundred kilohertz could serve as an optimal frequency at which to measure EIM phase values of the tongue in ALS. Muscle Nerve 55: 539-543, 2017.
    Mesh-Begriff(e) Adult ; Aged ; Amyotrophic Lateral Sclerosis/diagnosis ; Amyotrophic Lateral Sclerosis/pathology ; Electric Impedance ; Female ; Humans ; Male ; Middle Aged ; Muscle, Skeletal/physiopathology ; Myography ; Reproducibility of Results ; Tongue/physiopathology ; Young Adult
    Sprache Englisch
    Erscheinungsdatum 2017
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 438353-9
    ISSN 1097-4598 ; 0148-639X
    ISSN (online) 1097-4598
    ISSN 0148-639X
    DOI 10.1002/mus.25375
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Best practices protocol for the evaluation of bulbar dysfunction: summary recommendations from the NEALS bulbar subcommittee symposium.

    Pattee, Gary L / Plowman, Emily K / Brooks, Benjamin R / Berry, James D / Atassi, Nazem / Chapin, Jennifer L / Garand, Kendrea / Yunusova, Yana / Mcilduff, Courtney E / Young, Eufrosina / Costello, John M / Macklin, Eric A / Locatelli, Eduardo R / Silani, Vincenzo / Heitzman, Daragh / Wymer, James / Goutman, Stephen A / Gelinas, Deborah F / Smith, Richard /
    Perry, Bridget / Nalipinski, Paige / Stipancic, Kaila / O'Brien, Meghan / Sullivan, Stacey L / Green, Jordan

    Amyotrophic lateral sclerosis & frontotemporal degeneration

    2017  Band 19, Heft 3-4, Seite(n) 311–312

    Abstract: Objective: The aim of this Symposium was to develop a consensus based, bulbar assessment protocol for implementation within NEALS clinics.: Methods: A one-day symposium, held in April 2017, was organized into Speech and Swallowing sections to ... ...

    Abstract Objective: The aim of this Symposium was to develop a consensus based, bulbar assessment protocol for implementation within NEALS clinics.
    Methods: A one-day symposium, held in April 2017, was organized into Speech and Swallowing sections to establish summary recommendations for the assessment of bulbar dysfunction within each group.
    Results: Summary recommendations included speech referrals and AAC evaluations at initial visit, CNS-BFS, maximum sustained phonation, and speaking rate. Dysarthria evaluation included the speech subsystem involvement of respiration, phonation, resonance, and articulation. Specific recommendations for swallowing were established for each of the following domains: dietary/oral intake, airway defense physiologic capacity, swallow safety screen, patient-reported swallow-related outcomes, oral sensorimotor exam, and pulmonary function. Practice parameters focused upon patient education and unresolved questions included the use of videofluoscopy, monitoring diet progression, and swallow safety screening.
    Conclusions: The working goal is to establish a clinical bulbar protocol, designed to be incorporated within ALS clinics and ultimately to formulate a best practice set of bulbar ALS guidelines, available for implementation throughout the international ALS community.
    Mesh-Begriff(e) Amyotrophic Lateral Sclerosis/complications ; Deglutition Disorders/diagnosis ; Deglutition Disorders/etiology ; Disease Progression ; Dysarthria/diagnosis ; Dysarthria/etiology ; Female ; Humans ; Male ; Retrospective Studies ; Severity of Illness Index ; Speech Disorders/diagnosis ; Speech Disorders/etiology
    Sprache Englisch
    Erscheinungsdatum 2017-12-05
    Erscheinungsland England
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2705049-X
    ISSN 2167-9223 ; 2167-8421
    ISSN (online) 2167-9223
    ISSN 2167-8421
    DOI 10.1080/21678421.2017.1404109
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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