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Artikel ; Online: NAADP-Evoked Ca

Pereira, Cássia Arruda de Souza / Medaglia, Natalia de Castro / Ureshino, Rodrigo Portes / Bincoletto, Claudia / Antonioli, Manuela / Fimia, Gian Maria / Piacentini, Mauro / Pereira, Gustavo José da Silva / Erustes, Adolfo Garcia / Smaili, Soraya Soubhi

International journal of molecular sciences

2023  Band 24, Heft 6

Abstract: Huntington's disease (HD) is a progressive neurodegenerative disease characterized by mutations in the huntingtin gene (mHtt), causing an unstable repeat of the CAG trinucleotide, leading to abnormal long repeats of polyglutamine (poly-Q) in the N- ... ...

Abstract Huntington's disease (HD) is a progressive neurodegenerative disease characterized by mutations in the huntingtin gene (mHtt), causing an unstable repeat of the CAG trinucleotide, leading to abnormal long repeats of polyglutamine (poly-Q) in the N-terminal region of the huntingtin, which form abnormal conformations and aggregates. Alterations in Ca
Mesh-Begriff(e) Mice ; Animals ; Calcium Channels/metabolism ; Astrocytes/metabolism ; Neurodegenerative Diseases/metabolism ; NADP/metabolism ; Lysosomes/metabolism ; Autophagy ; Calcium/metabolism ; Huntingtin Protein/genetics ; Huntingtin Protein/metabolism
Chemische Substanzen Calcium Channels ; NAADP (5502-96-5) ; NADP (53-59-8) ; Calcium (SY7Q814VUP) ; Huntingtin Protein
Sprache Englisch
Erscheinungsdatum 2023-03-15
Erscheinungsland Switzerland
Dokumenttyp Journal Article
ZDB-ID 2019364-6
ISSN 1422-0067 ; 1422-0067 ; 1661-6596
ISSN (online) 1422-0067
ISSN 1422-0067 ; 1661-6596
DOI 10.3390/ijms24065593
Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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