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  1. Buch ; Dissertation / Habilitation: Ätiologie der distalen Urethrastenosen bei Mädchen

    Menne, Tobias

    eine retrospektive Studie mit histomorphologischer und immunhistologischer Anfärbung der resezierten Stenosepräparate

    1998  

    Verfasserangabe vorgelegt von Tobias Menne
    Sprache Deutsch
    Umfang 83 Bl. : Ill., graph. Darst.
    Ausgabenhinweis [Mikrofiche-Ausg.]
    Dokumenttyp Buch ; Dissertation / Habilitation
    Dissertation / Habilitation Berlin, Freie Univ., Diss., 1998
    Anmerkung Mikrofiche-Ausg.: 1 Mikrofiche : 24x
    HBZ-ID HT009322024
    Datenquelle Katalog ZB MED Medizin, Gesundheit

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    Verfügbar in ZB MED Köln/Königswinter

    SignaturLeihstatusStandort
    1998 MB 2310 bestellbar zur Ausleihe Magazin

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  2. Artikel ; Online: Subclinical immune responses to nickel in sensitized individuals-a dose-response study.

    Wennervaldt, Michael / Vaher, Helen / Ahlström, Malin G / Bischofberger, Nuno / Menné, Torkil / Thyssen, Jacob P / Johansen, Jeanne D / Bonefeld, Charlotte M

    Contact dermatitis

    2024  Band 91, Heft 1, Seite(n) 1–10

    Abstract: Background: Nickel is the leading cause of contact allergy in Europe, with 14.5% of the adult population being sensitized. Despite regulations limiting nickel release from consumer items, the incidence and prevalence of nickel allergy remain high.: ... ...

    Abstract Background: Nickel is the leading cause of contact allergy in Europe, with 14.5% of the adult population being sensitized. Despite regulations limiting nickel release from consumer items, the incidence and prevalence of nickel allergy remain high.
    Objective: To investigate the clinical and subclinical immune response to low-dose nickel exposure on nickel pre-exposed skin to assess the adequacy of current regulatory limits.
    Method: Nickel-allergic and healthy controls were patch tested with nickel twice with a 3-4 weeks interval. The first exposure used the diagnostic concentration of 2000 μg/cm
    Results: Two nickel-allergic participants (15%) had clinical reactions to the regulatory limiting doses for nickel (0.2/0.5 μg/cm
    Conclusion: Immune activation can be induced in skin with local memory to nickel upon challenge with nickel doses within the regulatory limits. Our findings suggest that the regulatory limits in the European nickel regulation may not provide sufficient protection for consumers against low-dose exposures.
    Mesh-Begriff(e) Humans ; Nickel/adverse effects ; Nickel/immunology ; Dermatitis, Allergic Contact/etiology ; Dermatitis, Allergic Contact/immunology ; Dermatitis, Allergic Contact/diagnosis ; Patch Tests ; Adult ; Female ; Male ; Middle Aged ; Case-Control Studies ; Cytokines/metabolism ; Dose-Response Relationship, Drug ; Young Adult ; Skin/drug effects ; Skin/immunology
    Chemische Substanzen Nickel (7OV03QG267) ; nickel sulfate (4FLT4T3WUN) ; Cytokines
    Sprache Englisch
    Erscheinungsdatum 2024-04-05
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 193121-0
    ISSN 1600-0536 ; 0105-1873
    ISSN (online) 1600-0536
    ISSN 0105-1873
    DOI 10.1111/cod.14549
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Buch ; Dissertation / Habilitation: NICKEL ALLERGY

    Menné, Torkil

    THE GENETIC AND EPIDEMIOLOGICAL ASPECTS ; RELATION BETWEEN NICKEL ALLERGY AND HAND ECZEMA

    1983  

    Umfang 69 S.
    Dokumenttyp Buch ; Dissertation / Habilitation
    Dissertation / Habilitation KOEBENHAVN, UNIV., DISS., 1983
    HBZ-ID HT002695518
    Datenquelle Katalog ZB MED Medizin, Gesundheit

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    Verfügbar in ZB MED Köln/Königswinter

    SignaturLeihstatusStandort
    84 E 156 bestellbar zur Ausleihe Magazin

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  4. Artikel ; Online: A qualitative service evaluation of patient and caregiver experiences of CAR-T therapy: Recommendations for service development and implications for palliative care teams.

    Stenson, Charlotte L / Vidrine, Jennifer / Dewhurst, Felicity / Osborne, Wendy / Menne, Tobias / Stocker, Rachel

    Palliative medicine

    2022  Band 37, Heft 2, Seite(n) 215–220

    Abstract: Background: Chimeric Antigen-Receptor-T-cell (CAR-T) therapy is a potentially life-saving treatment for refractory haematological malignancies. Internationally, CAR-T services are undergoing rapid development. Despite this, research on the lived ... ...

    Abstract Background: Chimeric Antigen-Receptor-T-cell (CAR-T) therapy is a potentially life-saving treatment for refractory haematological malignancies. Internationally, CAR-T services are undergoing rapid development. Despite this, research on the lived experiences of patients receiving novel immunotherapies is limited. Little is known about their supportive care needs. Consequently, dedicated palliative and supportive care services may not be considered.
    Aim: To explore the patient and caregiver experience of CAR-T therapy and identify unmet needs to inform service development.
    Design: A qualitative longitudinal service evaluation. Sixteen interviews were conducted between December 2020 and March 2021 with patients (
    Setting/participants: All patients and caregivers attending one UK centre for CAR-T therapy were eligible. Semi-structured interviews were conducted at specific time points: prior to infusion, one month after infusion and follow-up post-treatment (5-18 months).
    Results: Identified themes described the unique challenges of CAR-T therapy. From the point of referral patients had a wide range of supportive care needs. Initially, this was attributed to prior receipt of multiple failed treatments. Subsequently, CAR-T side-effects impacted on quality-of-life and physical function. Significant psychological morbidity from prognostic uncertainty was described throughout. Patients and caregivers reported that a dedicated nurse specialist - an expert, consistent point of contact - was essential.
    Conclusion: Patients and caregivers would benefit from early and ongoing support from palliative care, allied-health professionals and psychology. As indications for CAR-T therapy expand, there is an urgent need for multi-centre studies incorporating patient-reported outcome data to ensure patient-centred service delivery.
    Mesh-Begriff(e) Humans ; Palliative Care/psychology ; Caregivers/psychology ; Receptors, Chimeric Antigen ; Hospice and Palliative Care Nursing ; Hematologic Neoplasms ; Qualitative Research
    Chemische Substanzen Receptors, Chimeric Antigen
    Sprache Englisch
    Erscheinungsdatum 2022-11-25
    Erscheinungsland England
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 639247-7
    ISSN 1477-030X ; 0269-2163
    ISSN (online) 1477-030X
    ISSN 0269-2163
    DOI 10.1177/02692163221138880
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: Copper release from metals may mask positive nickel spot test results.

    Wennervaldt, Michael / Ahlström, Malin G / Menné, Torkil / Thyssen, Jacob P / Johansen, Jeanne D

    Contact dermatitis

    2022  Band 86, Heft 5, Seite(n) 431–433

    Mesh-Begriff(e) Copper/adverse effects ; Dermatitis, Allergic Contact/diagnosis ; Dermatitis, Allergic Contact/etiology ; Humans ; Jewelry/adverse effects ; Metals ; Nickel/adverse effects ; Oximes
    Chemische Substanzen Metals ; Oximes ; Copper (789U1901C5) ; Nickel (7OV03QG267)
    Sprache Englisch
    Erscheinungsdatum 2022-02-01
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 193121-0
    ISSN 1600-0536 ; 0105-1873
    ISSN (online) 1600-0536
    ISSN 0105-1873
    DOI 10.1111/cod.14049
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel ; Online: Impact of atopic dermatitis on occupational contact dermatitis among young people: A retrospective cohort study.

    Dietz, Jojo B / Menné, Torkil / Meyer, Harald W / Viskum, Sven / Flyvholm, Mari-Ann / Ahrensbøll-Friis, Ulrik / John, Swen M / Johansen, Jeanne D

    Contact dermatitis

    2023  Band 90, Heft 2, Seite(n) 143–152

    Abstract: Background: Occupational contact dermatitis (OCD) is a common occupational disease. Atopic dermatitis (AD) is a known risk factor for OCD.: Objectives: To determine the prevalence of previously diagnosed AD among young workers with recognized OCD and ...

    Abstract Background: Occupational contact dermatitis (OCD) is a common occupational disease. Atopic dermatitis (AD) is a known risk factor for OCD.
    Objectives: To determine the prevalence of previously diagnosed AD among young workers with recognized OCD and assess its impact on OCD prognosis.
    Methods: A retrospective cohort study. A questionnaire was sent to 6251 workers with recognized OCD who were under 35 years at notification (response rate: 47%). Of the respondents, 2392 answered a question about previous doctor-diagnosed AD and were included in the study. Eczema severity, occupational consequences and quality of life were examined using statistical analyses comparing workers with and without previously diagnosed AD.
    Results: The prevalence of previously diagnosed AD was 41.8% (95% CI: 39.8-43.8). Women had a higher AD prevalence, and workers with AD reported OCD at a younger age. Workers with AD reported more frequent and severe eczema symptoms and had a higher risk of OCD negatively affecting job and occupation choices. Health-related quality of life was more adversely affected in workers with AD.
    Conclusions: AD significantly impacts severity and has long-term consequences for young people with OCD. Targeted prevention strategies need to be developed.
    Mesh-Begriff(e) Humans ; Female ; Adolescent ; Dermatitis, Atopic/epidemiology ; Dermatitis, Atopic/complications ; Dermatitis, Allergic Contact/epidemiology ; Dermatitis, Allergic Contact/etiology ; Dermatitis, Allergic Contact/diagnosis ; Quality of Life ; Retrospective Studies ; Dermatitis, Occupational/epidemiology ; Dermatitis, Occupational/etiology ; Dermatitis, Occupational/diagnosis ; Eczema/complications
    Sprache Englisch
    Erscheinungsdatum 2023-09-26
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 193121-0
    ISSN 1600-0536 ; 0105-1873
    ISSN (online) 1600-0536
    ISSN 0105-1873
    DOI 10.1111/cod.14426
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel ; Online: Contact allergy to rubber accelerators remains prevalent: retrospective results from a tertiary clinic suggesting an association with facial dermatitis.

    Schwensen, J F / Menné, T / Johansen, J D / Thyssen, J P

    Journal of the European Academy of Dermatology and Venereology : JEADV

    2016  Band 30, Heft 10, Seite(n) 1768–1773

    Abstract: Introduction: Chemicals used for the manufacturing of rubber are known causes of allergic contact dermatitis on the hands. Recent European studies have suggested a decrease in thiuram contact allergy. Moreover, while an association with hand dermatitis ... ...

    Abstract Introduction: Chemicals used for the manufacturing of rubber are known causes of allergic contact dermatitis on the hands. Recent European studies have suggested a decrease in thiuram contact allergy. Moreover, while an association with hand dermatitis is well established, we have recently observed several clinical cases with allergic facial dermatitis to rubber.
    Objectives: To evaluate temporal trends of contact allergy to rubber accelerators from the European baseline series in a tertiary patch test clinic in Denmark, and examine associations with anatomical locations of dermatitis.
    Methods: Patch test and clinical data collected in a Danish tertiary dermatology clinic in Gentofte, Herlev, Copenhagen between 1 January 2005 and 31 December 2014 were analysed. The following rubber accelerators or mixtures in petrolatum from the European baseline patch test series were included: thiuram mix 1.0%, mercaptobenzothiazole 2.0% and mercapto mix 1.0%.
    Results: The overall prevalence of contact allergy to rubber accelerators was 3.1% with no significant change during the study period (P
    Conclusion: Contact allergy to rubber accelerators remains prevalent. Clinicians should be aware of the hitherto unexplored clinical association with facial dermatitis.
    Mesh-Begriff(e) Adult ; Dermatitis, Contact/epidemiology ; Face ; Female ; Humans ; Male ; Prevalence ; Retrospective Studies ; Rubber
    Chemische Substanzen Rubber (9006-04-6)
    Sprache Englisch
    Erscheinungsdatum 2016-10
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 1128828-0
    ISSN 1468-3083 ; 0926-9959
    ISSN (online) 1468-3083
    ISSN 0926-9959
    DOI 10.1111/jdv.13684
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel ; Online: Nickel release from metallic earrings: A survey of the Danish market and validation of the nickel spot test.

    Wennervaldt, Michael / Ahlström, Malin G / Menné, Torkil / Thyssen, Jacob P / Johansen, Jeanne D

    Contact dermatitis

    2021  

    Abstract: Background: Exposure to nickel-releasing ear-piercing jewellery may explain the persistently high prevalence of nickel allergy in Europe. While nickel release from earrings is regulated, field studies show that the regulation is not always respected. ... ...

    Abstract Background: Exposure to nickel-releasing ear-piercing jewellery may explain the persistently high prevalence of nickel allergy in Europe. While nickel release from earrings is regulated, field studies show that the regulation is not always respected. More knowledge is needed regarding the risk of piercing exposure including suitable screening methods.
    Objective: To examine the proportion of earrings on the Danish market that release more nickel than allowed, and to validate the use of the dimethylglyoxime (DMG) test as a screening tool.
    Methods: A total of 304 earrings were purchased and tested with the DMG test and X-ray fluorescence spectrometry. The level of nickel release was quantified in a selected subsample of 100 earrings by the European reference test EN 1811. The DMG spot test was validated against EN 1811 at different thresholds.
    Results: Excessive nickel release according to the European regulation was found in 45 (14.8%) tested earrings. The sensitivity of the DMG test decreased with reduced levels of nickel release (sensitivity of 45.2% at ≥0.2 μg/cm
    Conclusion: Excessive nickel release is common in earrings on the Danish market. Because of low sensitivity, the DMG test has limited use in screening of earrings for research but may still be used clinically.
    Sprache Englisch
    Erscheinungsdatum 2021-03-13
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 193121-0
    ISSN 1600-0536 ; 0105-1873
    ISSN (online) 1600-0536
    ISSN 0105-1873
    DOI 10.1111/cod.13832
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel ; Online: Occupational contact dermatitis among young people in Denmark - A survey of causes and long-term consequences.

    Dietz, Jojo B / Menné, Torkil / Meyer, Harald W / Viskum, Sven / Flyvholm, Mari-Ann / Ahrensbøll-Friis, Ulrik / John, Swen M / Johansen, Jeanne D

    Contact dermatitis

    2022  Band 86, Heft 5, Seite(n) 404–416

    Abstract: Background: Studies on the causes and consequences of occupational contact dermatitis (OCD) among young workers are non-existent.: Objectives: Determine causes and consequences of OCD among workers younger than 35 years of age.: Methods: A ... ...

    Abstract Background: Studies on the causes and consequences of occupational contact dermatitis (OCD) among young workers are non-existent.
    Objectives: Determine causes and consequences of OCD among workers younger than 35 years of age.
    Methods: A questionnaire was sent to 6251 workers younger than 35 years at notification with recognized OCD (response rate 47%).
    Results: The most prevalent occupations were health care workers, kitchen workers, nursery teachers, and hairdressers and beauticians. Seventy-six percent still had eczema, and 77% of these had eczema half to all the time over the last 3 months, with 61% evaluating their eczema as moderate to very severe. Fifty-three percent had changed their occupation since notification, and 42.5% had lost their job because of OCD. Allergic OCD increased the odds ratio (OR) for facial or foot eczema, job loss, change in work tasks, difficulties finding work, decrease in income, and sick leave. Age at notification of 25 years of age or younger increased the risk of job loss and feeling restricted in choice of job. Workers in the food industry had a higher OR for job loss, whereas hairdressers and beauticians had a higher risk of job loss and a decrease in income.
    Conclusions: The severe, long-term consequences of OCD notification signify the need for further preventive strategies among young workers.
    Mesh-Begriff(e) Adolescent ; Denmark/epidemiology ; Dermatitis, Allergic Contact/epidemiology ; Dermatitis, Allergic Contact/etiology ; Dermatitis, Occupational/complications ; Dermatitis, Occupational/etiology ; Eczema/complications ; Eczema/etiology ; Humans ; Surveys and Questionnaires
    Sprache Englisch
    Erscheinungsdatum 2022-03-09
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 193121-0
    ISSN 1600-0536 ; 0105-1873
    ISSN (online) 1600-0536
    ISSN 0105-1873
    DOI 10.1111/cod.14050
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  10. Artikel ; Online: Clinical consequences of sesquiterpene lactone mix contact allergy in Denmark.

    Andersen, R M / Skov, L / Menné, T / Johansen, J D

    The British journal of dermatology

    2015  Band 172, Heft 5, Seite(n) 1430–1431

    Mesh-Begriff(e) Activities of Daily Living ; Adrenal Cortex Hormones/therapeutic use ; Asteraceae/adverse effects ; Azathioprine/therapeutic use ; Denmark/epidemiology ; Dermatitis, Allergic Contact/drug therapy ; Dermatitis, Allergic Contact/epidemiology ; Dermatitis, Allergic Contact/etiology ; Female ; Humans ; Immunosuppressive Agents/therapeutic use ; Lactones/adverse effects ; Male ; Methotrexate/therapeutic use ; Middle Aged ; Patch Tests ; Seasons ; Sesquiterpenes/adverse effects
    Chemische Substanzen Adrenal Cortex Hormones ; Immunosuppressive Agents ; Lactones ; Sesquiterpenes ; Azathioprine (MRK240IY2L) ; Methotrexate (YL5FZ2Y5U1)
    Sprache Englisch
    Erscheinungsdatum 2015
    Erscheinungsland England
    Dokumenttyp Letter
    ZDB-ID 80076-4
    ISSN 1365-2133 ; 0007-0963
    ISSN (online) 1365-2133
    ISSN 0007-0963
    DOI 10.1111/bjd.13584
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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