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  1. Artikel ; Online: Monofilament threads in treatment of female hair loss.

    Metwalli, Mohamed / Khattab, Fathia M / Mandour, Samira

    The Journal of dermatological treatment

    2020  Band 32, Heft 5, Seite(n) 521–525

    Abstract: Background: Recently, thread treatment has been commonly used in Korean medicine for cosmetic reasons such as decreasing skin wrinkles. It was noted that an inserted thread caused constant stimulation, followed by assistance for connective tissue ... ...

    Abstract Background: Recently, thread treatment has been commonly used in Korean medicine for cosmetic reasons such as decreasing skin wrinkles. It was noted that an inserted thread caused constant stimulation, followed by assistance for connective tissue regeneration. However, its role in hair development has not yet been revealed.
    Objective: To perform a pilot study on the effect of monofilament threads scalp injections in women with female androgenetic alopecia.
    Materials and methods: This double-blind, multicenter, placebo-controlled study compared the effect of monofilament threads with that of saline as placebo. The endpoints were hair count and hair mass index (HMI), along with patient-opinion survey responses.
    Results: HMI or hair count has statistically significantly differed between the study and placebo groups. However, 73.3% of the treatment subjects (vs. 0% of the placebo subjects) experienced substantial improvement in hair loss, rate of hair loss, hair thickness, and ease of managing/styling hair, and 76.8% (vs. 18.4% of the placebo group) reported that their hair felt coarser or heavier after the treatment.
    Conclusion: Monofilament threads demonstrate highly statistically significant improvement in HMI or hair count in women female pattern hair loss. The patient survey results suggest a therapeutic advantage of monofilament threads as perceived by patients and according to hair count or HMI.
    Mesh-Begriff(e) Adult ; Alopecia/therapy ; Double-Blind Method ; Female ; Hair/growth & development ; Humans ; Pilot Projects ; Prospective Studies ; Scalp
    Sprache Englisch
    Erscheinungsdatum 2020-03-03
    Erscheinungsland England
    Dokumenttyp Journal Article ; Randomized Controlled Trial
    ZDB-ID 1036299-x
    ISSN 1471-1753 ; 0954-6634
    ISSN (online) 1471-1753
    ISSN 0954-6634
    DOI 10.1080/09546634.2019.1682499
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Combination of oral methotrexate and oral mini-pulse dexamethasone vs either agent alone in vitiligo treatment with follow up by dermoscope.

    ElGhareeb, Mohamed Ibrahim / Metwalli, Mohamed / AbdelMoneim, Nehal

    Dermatologic therapy

    2020  Band 33, Heft 4, Seite(n) e13586

    Abstract: This study aimed to compare the efficacy and safety of oral methotrexate (MTX) and oral mini-pulse (OMP) dexamethasone alone and in combination in the treatment of vitiligo. A total of 42 patients with vitiligo were included in the study. The patients ... ...

    Abstract This study aimed to compare the efficacy and safety of oral methotrexate (MTX) and oral mini-pulse (OMP) dexamethasone alone and in combination in the treatment of vitiligo. A total of 42 patients with vitiligo were included in the study. The patients were treated for three months and randomly assigned into three groups including 14 patients each: group A received oral MTX, group B received OMP dexamethasone, and group C received a combination of both. Follow-up was performed using digital photographs, Vitiligo European Task Force score, and dermoscopy. Disease extension significantly decreased in group C compared with that in groups A (P < .001) and B (P < .05). The frequency of intralesional pigmentation significantly increased (P < .05) in groups A and C and decreased (P < .05) in group B posttreatment noted using a dermoscope. Moreover, the frequency of micro-Koebner's phenomenon and starburst pattern significantly decreased (P < .05) in groups B and C and that of tapioca sago in group C only posttreatment.
    Mesh-Begriff(e) Administration, Oral ; Dexamethasone/adverse effects ; Follow-Up Studies ; Humans ; Methotrexate/adverse effects ; Treatment Outcome ; Vitiligo/diagnosis ; Vitiligo/drug therapy
    Chemische Substanzen Dexamethasone (7S5I7G3JQL) ; Methotrexate (YL5FZ2Y5U1)
    Sprache Englisch
    Erscheinungsdatum 2020-05-28
    Erscheinungsland United States
    Dokumenttyp Clinical Trial ; Journal Article
    ZDB-ID 1354801-3
    ISSN 1529-8019 ; 1396-0296
    ISSN (online) 1529-8019
    ISSN 1396-0296
    DOI 10.1111/dth.13586
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Ruptured pancreaticoduodenal artery aneurysm presenting with duodenal obstruction

    Nakul Reddy, MD / Zeyad Ahmed Metwalli, MD

    Radiology Case Reports, Vol 14, Iss 5, Pp 568-

    2019  Band 571

    Abstract: Visceral aneurysms of the pancreaticoduodenal arcades are rare. Although these aneurysms are often asymptomatic and identified incidentally on cross-sectional imaging, aneurysm rupture presents significant morbidity. Ruptured pancreaticoduodenal arcade ... ...

    Abstract Visceral aneurysms of the pancreaticoduodenal arcades are rare. Although these aneurysms are often asymptomatic and identified incidentally on cross-sectional imaging, aneurysm rupture presents significant morbidity. Ruptured pancreaticoduodenal arcade aneurysms typically present with abdominal pain, hemorrhagic shock, or gastrointestinal bleeding. A 72-year-old male presented with nausea and vomiting and was found to have imaging evidence of duodenal obstruction. This was due to a duodenal intramural hematoma caused by a ruptured submucosal aneurysm supplied by a branch of the inferior pancreaticoduodenal artery in the presence of median arcuate ligament compression of the celiac artery. This was subsequently treated with endovascular embolization with clinical improvement in duodenal obstruction. This case illustrates an unusual presentation of a ruptured pancreaticoduodenal arcade aneurysm. Keywords: Pancreaticoduodenal artery aneurysm, Duodenal stenosis, Duodenal obstruction
    Schlagwörter Medical physics. Medical radiology. Nuclear medicine ; R895-920
    Sprache Englisch
    Erscheinungsdatum 2019-05-01T00:00:00Z
    Verlag Elsevier
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  4. Artikel: Topical liquiritin improves melasma.

    Amer, M / Metwalli, M

    International journal of dermatology

    2000  Band 39, Heft 4, Seite(n) 299–301

    Abstract: Twenty women with a clinical diagnosis of melasma were treated with liquiritin cream on one side of the face and with a vehicle cream on the other side twice daily for 4 weeks. Patients were advised to avoid sun exposure and/or used topical sunscreen ... ...

    Abstract Twenty women with a clinical diagnosis of melasma were treated with liquiritin cream on one side of the face and with a vehicle cream on the other side twice daily for 4 weeks. Patients were advised to avoid sun exposure and/or used topical sunscreen during the entire period of treatment. Inclusion criteria included an age range from 18 to 40 years and bilateral and symmetrical idiopathic epidermal melasma. Exclusion criteria included patients with dermal melasma (differentiated by Wood's light), melasma with pregnancy, and patients currently receiving hormone replacement therapy. Melasma pigmentary intensity was rated on a five-point scale in relation to the patient's normal facial skin (1, no difference; 2, slightly more pigmented; 3, moderately more pigmented; 4, markedly more pigmented; and 5, intensely more pigmented). The size of the lesions was measured directly using a millimeter grid scale. Ratings and measurements were made prior to treatment and at each of the follow-up visits (after 2, 4, 6, 8, and 10 weeks). Clinical evaluation was performed at week 4; the overall response was rated as excellent, good, fair, or poor. Color photographs were taken at the start and at week 4 of the study. Side-effects were observed and treated.
    Mesh-Begriff(e) Administration, Topical ; Adolescent ; Adult ; Female ; Glycyrrhetinic Acid/therapeutic use ; Humans ; Melanosis/drug therapy ; Melanosis/pathology ; Ointments ; Treatment Outcome
    Chemische Substanzen Ointments ; Glycyrrhetinic Acid (P540XA09DR)
    Sprache Englisch
    Erscheinungsdatum 2000-04
    Erscheinungsland England
    Dokumenttyp Clinical Trial ; Controlled Clinical Trial ; Journal Article
    ZDB-ID 412254-9
    ISSN 1365-4632 ; 0011-9059 ; 1461-1244
    ISSN (online) 1365-4632
    ISSN 0011-9059 ; 1461-1244
    DOI 10.1046/j.1365-4362.2000.00943.x
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel: Cutaneous vasculitis in western Africa.

    Amer, M / Metwalli, M

    Clinics in dermatology

    1999  Band 17, Heft 6, Seite(n) 655–658

    Mesh-Begriff(e) Africa, Western/epidemiology ; Female ; Humans ; Incidence ; Male ; Risk Factors ; Skin Diseases, Vascular/epidemiology ; Skin Diseases, Vascular/etiology ; Vasculitis/epidemiology ; Vasculitis/etiology
    Sprache Englisch
    Erscheinungsdatum 1999-11
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Review
    ZDB-ID 1064149-x
    ISSN 0738-081X
    ISSN 0738-081X
    DOI 10.1016/s0738-081x(99)00070-x
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel: Topical hydroquinone in the treatment of some hyperpigmentary disorders.

    Amer, M / Metwalli, M

    International journal of dermatology

    1998  Band 37, Heft 6, Seite(n) 449–450

    Mesh-Begriff(e) Adolescent ; Adult ; Dermatologic Agents/therapeutic use ; Female ; Humans ; Hydroquinones/therapeutic use ; Hyperpigmentation/drug therapy ; Male ; Middle Aged ; Treatment Outcome
    Chemische Substanzen Dermatologic Agents ; Hydroquinones ; hydroquinone (XV74C1N1AE)
    Sprache Englisch
    Erscheinungsdatum 1998-06
    Erscheinungsland England
    Dokumenttyp Clinical Trial ; Journal Article
    ZDB-ID 412254-9
    ISSN 1365-4632 ; 0011-9059 ; 1461-1244
    ISSN (online) 1365-4632
    ISSN 0011-9059 ; 1461-1244
    DOI 10.1046/j.1365-4362.1998.00499.x
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel: Environmental dermatology: an overview.

    Amer, M / Metwalli, M

    Clinics in dermatology

    1998  Band 16, Heft 1, Seite(n) 23–25

    Mesh-Begriff(e) Air Pollutants/adverse effects ; Causality ; Environmental Exposure/adverse effects ; Humans ; Risk Assessment ; Skin Diseases/diagnosis ; Skin Diseases/epidemiology ; Skin Diseases/etiology ; Socioeconomic Factors
    Chemische Substanzen Air Pollutants
    Sprache Englisch
    Erscheinungsdatum 1998-01
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Review
    ZDB-ID 1064149-x
    ISSN 0738-081X
    ISSN 0738-081X
    DOI 10.1016/s0738-081x(97)00166-1
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  8. Artikel: Skin diseases and enzymatic antioxidant activity among workers exposed to pesticides.

    Amer, M / Metwalli, M / Abu el-Magd, Y

    Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit

    2002  Band 8, Heft 2-3, Seite(n) 363–373

    Abstract: In this study, 150 workers exposed to pesticides and 50 healthy control subjects were given clinical and dermatological examinations, patch tests, tests of liver and renal function, complete blood count, blood sugar and urinalysis. Activity of the ... ...

    Abstract In this study, 150 workers exposed to pesticides and 50 healthy control subjects were given clinical and dermatological examinations, patch tests, tests of liver and renal function, complete blood count, blood sugar and urinalysis. Activity of the antioxidant enzymes superoxide dismutase, glutathione peroxidase and glutathione reductase was also evaluated. Dermatological findings were positive in 78%, 76% and 54% of workers exposed to organophosphates, pyrethroids and carbamate pesticides respectively. The patch test was positive in 70% of workers exposed to pyrethroids and 64% exposed to carbamate pesticides. Liver enzyme levels were generally increased in workers while antioxidant enzyme activity was significantly decreased in all workers compared with the controls.
    Mesh-Begriff(e) Adult ; Age Distribution ; Analysis of Variance ; Antioxidants/metabolism ; Carbaryl/poisoning ; Case-Control Studies ; Chemical Industry ; Dermatitis, Occupational/enzymology ; Dermatitis, Occupational/epidemiology ; Dermatitis, Occupational/etiology ; Diazinon/poisoning ; Egypt/epidemiology ; Glutathione Peroxidase/blood ; Glutathione Reductase/blood ; Humans ; Kidney Function Tests ; Lipid Peroxidation ; Liver Function Tests ; Male ; Middle Aged ; Occupational Exposure/adverse effects ; Occupational Exposure/analysis ; Occupational Exposure/statistics & numerical data ; Pesticides/poisoning ; Pyrethrins/poisoning ; Skin Absorption ; Skin Tests ; Superoxide Dismutase/blood ; Time Factors ; Urban Health/statistics & numerical data
    Chemische Substanzen Antioxidants ; Pesticides ; Pyrethrins ; Glutathione Peroxidase (EC 1.11.1.9) ; Superoxide Dismutase (EC 1.15.1.1) ; Glutathione Reductase (EC 1.8.1.7) ; Carbaryl (R890C8J3N1) ; Diazinon (YUS1M1Q929)
    Sprache Englisch
    Erscheinungsdatum 2002-03
    Erscheinungsland Egypt
    Dokumenttyp Journal Article
    ZDB-ID 1291071-5
    ISSN 1687-1634 ; 1020-3397
    ISSN (online) 1687-1634
    ISSN 1020-3397
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Buch ; Online: Skin diseases and enzymatic antioxidant activity among workers exposed to pesticides

    Amer, M. / Metwalli, M. / Abu El Magd, Y.

    2002  

    Abstract: 363-373 ... In this study, 150 workers exposed to pesticides and 50 healthy control subjects were given clinical and dermatological examinations, patch tests, tests of liver and renal function, complete blood count, blood sugar and urinalysis. Activity of ... ...

    Abstract 363-373

    In this study, 150 workers exposed to pesticides and 50 healthy control subjects were given clinical and dermatological examinations, patch tests, tests of liver and renal function, complete blood count, blood sugar and urinalysis. Activity of the antioxidant enzymes superoxide dismutase, glutathione peroxidase and glutathione reductase was also evaluated. Dermatological findings were positive in 78%, 76% and 54% of workers exposed to organophosphates, pyrethroids and carbamate pesticides respectively. The patch test was positive in 70% of workers exposed to pyrethroids and 64% exposed to carbamate pesticides. Liver enzyme levels were generally increased in workers while antioxidant enzyme activity was significantly decreased in all workers compared with the controls
    Schlagwörter Age Distribution ; Antioxidants ; Carbaryl ; Case-Control Studies ; Chemical Industry ; Dermatitis ; Occupational ; Glutathione Peroxidase ; Glutathione Reductase ; Liver Function Tests ; Skin Absorption ; Superoxide Dismutase ; Pesticides
    Sprache Englisch
    Dokumenttyp Buch ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  10. Artikel: Spectrophotometric determination of nizatidine and ranitidine through charge transfer complex formation.

    Walash, M / Sharaf-El Din, M / Metwalli, M E-S / RedaShabana, M

    Archives of pharmacal research

    2004  Band 27, Heft 7, Seite(n) 720–726

    Abstract: Two Spectrophotometric procedures are presented for the determination of two commonly used H2-receptor antagonists, nizatidine (I) and ranitidine hydrochloride (II). The methods are based mainly on charge transfer complexation reaction of these drugs ... ...

    Abstract Two Spectrophotometric procedures are presented for the determination of two commonly used H2-receptor antagonists, nizatidine (I) and ranitidine hydrochloride (II). The methods are based mainly on charge transfer complexation reaction of these drugs with either p-chloranilic acid (rho-CA) or 2, 3 dichloro-5, 6-dicyanoquinone (DDQ). The produced colored products are quantified spectrophotometrically at 515 and 467 nm in chloranilic acid and DDQ methods, respectively. The molar ratios for the reaction products and the optimum assay conditions were studied. The methods determine the cited drugs in concentration ranges of 20-200 and 20-160 microg/mL for nizatidine and ranges of 20-240 and 20-140 microg/mL for ranitidine with chloranilic acid and DDQ methods, respectively. A more detailed investigation of the complexes formed was made with respect to their composition, association constant, molar absorptivity and free energy change. The proposed procedures were successfully utilized in the determination of the drugs in pharmaceutical preparations. The standard addition method was applied by adding nizatidine and ranitidine to the previously analyzed tablets or capsules. The recovery of each drug was calculated by comparing the concentration obtained from the spiked mixtures with those of the pure drug. The results of analysis of commercial tablets and the recovery study (standard addition method) of the cited drugs suggested that there is no interference from any excipients, which are present in tablets or capsules. Statistical comparison of the results was performed with regard to accuracy and precision using student's t-test and F-ratio at 95% confidence level. There is no significant difference between the reported and proposed methods with regard to accuracy and precision.
    Mesh-Begriff(e) Anti-Ulcer Agents/analysis ; Benzoquinones/chemistry ; Capsules ; Chemical Phenomena ; Chemistry, Physical ; Indicators and Reagents ; Nizatidine/analysis ; Ranitidine/analysis ; Reference Standards ; Reproducibility of Results ; Solutions ; Spectrophotometry, Ultraviolet ; Tablets
    Chemische Substanzen Anti-Ulcer Agents ; Benzoquinones ; Capsules ; Indicators and Reagents ; Solutions ; Tablets ; dichlorodicyanobenzoquinone (1H5KD39UH7) ; Ranitidine (884KT10YB7) ; Nizatidine (P41PML4GHR) ; chloranilic acid (YJ8L3BB7Y4)
    Sprache Englisch
    Erscheinungsdatum 2004-07-21
    Erscheinungsland Korea (South)
    Dokumenttyp Journal Article
    ZDB-ID 447623-2
    ISSN 1976-3786 ; 0253-6269
    ISSN (online) 1976-3786
    ISSN 0253-6269
    DOI 10.1007/bf02980138
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