Artikel ; Online: The Safety of Anti-SARS-CoV-2 Vaccines
Journal of Clinical Medicine, Vol 11, Iss 1248, p
Vigilance Is Still Required
2022 Band 1248
Abstract: The opinion I put forward in this paper is that attention must continue to be paid to clinical observations compatible with a detrimental effect of anti-SARS-CoV-2 in certain diseases of immunological nature. Using the example of the atypical ... ...
Abstract | The opinion I put forward in this paper is that attention must continue to be paid to clinical observations compatible with a detrimental effect of anti-SARS-CoV-2 in certain diseases of immunological nature. Using the example of the atypical thrombocytopenic thromboses caused by adenoviral-vector-based vaccines, I argue that usual post-marketing pharmacovigilance programs may fail in identifying very rare vaccine-related disorders. Since the robust protective immunity induced by mRNA vaccines is related to their distinct capacity to induce strong stimulation of T follicular helper cells, I suggest that the safety of mRNA vaccines should be further assessed by appropriately designed epidemiological and mechanistic studies focusing on lymphoproliferative and autoimmune diseases in which T follicular helper cells were found to play a key role. |
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Schlagwörter | COVID-19 ; SARS-CoV-2 ; vaccine ; mRNA lymphoma ; T cell ; autoimmunity ; Medicine ; R |
Sprache | Englisch |
Erscheinungsdatum | 2022-02-01T00:00:00Z |
Verlag | MDPI AG |
Dokumenttyp | Artikel ; Online |
Datenquelle | BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl) |
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