Artikel ; Online: The renaissance of alpha-methylene-gamma-butyrolactones: new synthetic approaches.
Angewandte Chemie (International ed. in English)
2009 Band 48, Heft 50, Seite(n) 9426–9451
Abstract: The amount of research activity concerning alpha-methylene-gamma-butyrolactones and alpha-alkylidene-gamma-butyrolactones has increased dramatically in recent years. This Review summarizes the structural types, biological activities, and biosynthesis of ... ...
Abstract | The amount of research activity concerning alpha-methylene-gamma-butyrolactones and alpha-alkylidene-gamma-butyrolactones has increased dramatically in recent years. This Review summarizes the structural types, biological activities, and biosynthesis of these compounds, concentrating on publications from the past 10 years. Traditional approaches to alpha-methylene-gamma-butyrolactones and alpha-alkylidene-gamma-butyrolactones are then reviewed together with novel approaches, including those from our own research group, reported more recently. |
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Mesh-Begriff(e) | 4-Butyrolactone/analogs & derivatives ; 4-Butyrolactone/biosynthesis ; 4-Butyrolactone/chemical synthesis ; 4-Butyrolactone/therapeutic use ; Drug Evaluation, Preclinical ; Molecular Structure ; Structure-Activity Relationship |
Chemische Substanzen | alpha-methylene gamma-butyrolactone (362Y256BOL) ; 4-Butyrolactone (OL659KIY4X) |
Sprache | Englisch |
Erscheinungsdatum | 2009-11-20 |
Erscheinungsland | Germany |
Dokumenttyp | Journal Article ; Research Support, Non-U.S. Gov't ; Review |
ZDB-ID | 2011836-3 |
ISSN | 1521-3773 ; 1433-7851 |
ISSN (online) | 1521-3773 |
ISSN | 1433-7851 |
DOI | 10.1002/anie.200903108 |
Datenquelle | MEDical Literature Analysis and Retrieval System OnLINE |
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