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  1. AU="Morales-Ruiz, Valeria"
  2. TI=Prehemodialysis Care by Dietitians and First Year Mortality After Initiation of Hemodialysis

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  1. Article: Meta-analysis to Implement Alpha-Synuclein in Extracellular Vesicles as a Potential Biomarker for Parkinsons Disease.

    Juárez-Vaquera, Víctor H / Rosetti-Sciutto, Marcos F / Morales-Ruiz, Valeria / Adalid-Peralta, Laura V

    Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion

    2023  Volume 75, Issue 4, Page(s) 193–202

    Abstract: Background: ...

    Abstract Background:
    MeSH term(s) Humans ; alpha-Synuclein ; Biomarkers ; Extracellular Vesicles ; Parkinson Disease/diagnosis
    Chemical Substances alpha-Synuclein ; Biomarkers ; SNCA protein, human
    Language English
    Publishing date 2023-08-22
    Publishing country Mexico
    Document type Meta-Analysis ; Journal Article
    ZDB-ID 138348-6
    ISSN 0034-8376
    ISSN 0034-8376
    DOI 10.24875/RIC.23000017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 288: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Characterization of excretory/secretory products of the Taenia crassiceps cysticercus involved in the induction of regulatory T cells in vivo.

    Morales-Ruiz, Valeria / López-Recinos, Dina / Castañeda, María Gracia / Guevara-Salinas, Adrián / Parada-Colin, Cristina / Gómez-Fuentes, Sandra / Espitia-Pinzón, Clara / Hernández-González, Marisela / Adalid-Peralta, Laura

    Parasitology research

    2023  Volume 122, Issue 7, Page(s) 1489–1497

    Abstract: The ability to modulate the host immune response has allowed some parasites to establish themselves in the tissues of an immunocompetent organism. While some parasite excretion/secretion products (ESPs) were recently reported to induce differentiation of ...

    Abstract The ability to modulate the host immune response has allowed some parasites to establish themselves in the tissues of an immunocompetent organism. While some parasite excretion/secretion products (ESPs) were recently reported to induce differentiation of regulatory T cells (Tregs), their identity is not known. This work is aimed to identify and characterize ESPs of Taenia crassiceps cysticerci linked with Treg induction in vivo. ESPs were obtained from cultures of T. crassiceps cysticerci and inoculated in mice, measuring Treg levels by flow cytometry. Proteins in ESPs were analyzed by electrophoresis; then, ESPs were classified as either differential or conserved. Differentially included proteins were MS-sequenced and functionally characterized. Only 4 of 10 ESPs induced Tregs. Proteins with catalytic activity and those involved in immunological processes predominated, supporting the idea that these molecules could play an important role in the induction of Tregs.
    MeSH term(s) Animals ; Mice ; Taenia ; Cysticercus ; T-Lymphocytes, Regulatory ; Parasites ; Flow Cytometry ; Mice, Inbred BALB C
    Language English
    Publishing date 2023-04-28
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 284966-5
    ISSN 1432-1955 ; 0932-0113 ; 0044-3255
    ISSN (online) 1432-1955
    ISSN 0932-0113 ; 0044-3255
    DOI 10.1007/s00436-023-07847-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uh II Zs.124: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Efficacy of intravenous immunoglobulin in autoimmune neurological diseases. Literature systematic review and meta-analysis.

    Morales-Ruiz, Valeria / Juárez-Vaquera, Víctor Hugo / Rosetti-Sciutto, Marcos / Sánchez-Muñoz, Fausto / Adalid-Peralta, Laura

    Autoimmunity reviews

    2021  Volume 21, Issue 3, Page(s) 103019

    Abstract: Background: Corticosteroids are the first-line treatment for several common autoimmune neurological diseases. Other therapeutic approaches, including intravenous immunoglobulin (IVIg) and plasmapheresis, have shown mixed results in patient improvement.!# ...

    Abstract Background: Corticosteroids are the first-line treatment for several common autoimmune neurological diseases. Other therapeutic approaches, including intravenous immunoglobulin (IVIg) and plasmapheresis, have shown mixed results in patient improvement.
    Objective: To compare the efficacy of IVIg administration with that of corticosteroids, plasmapheresis, and placebo in autoimmune neurological diseases like Guillain-Barré syndrome, myasthenia gravis, chronic inflammatory demyelinating polyneuropathy, optic neuritis, and multiple sclerosis.
    Methods: A systematic review was performed on the databases PubMed, MEDLINE, Embase, and Cochrane. Controlled, randomized studies comparing the efficacy of IVIg with placebo, plasmapheresis, and/or glucocorticoid administration were selected. Only studies reporting the number of patients who improved after treatment were included, irrespective of language or publication year. In total, 23 reports were included in the meta-analysis study.
    Results: Our meta-analysis showed a beneficial effect of IVIg administration on patient improvement over placebo (OR = 2.79, CI [95%] = 1.40-5.55, P = 0.01). Meanwhile, IVIg administration showed virtually identical effects to plasmapheresis (OR = 0.83, CI [95%] = 0.45-1.55, P < 0.01). Finally, no significant differences were found in the efficacy of IVIg and glucocorticoid administration (OR = 0.98, Cl [95%] = 0.58-1.68, P = 0.13).
    Conclusion: IVIg can be regarded as a viable therapeutic approach, either as a first- or second-line therapy, and as an adjuvant therapy for autoimmune neurological diseases.
    MeSH term(s) Guillain-Barre Syndrome ; Humans ; Immunoglobulins, Intravenous/therapeutic use ; Myasthenia Gravis/drug therapy ; Plasma Exchange ; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating/drug therapy
    Chemical Substances Immunoglobulins, Intravenous
    Language English
    Publishing date 2021-12-15
    Publishing country Netherlands
    Document type Journal Article ; Meta-Analysis ; Review ; Systematic Review
    ZDB-ID 2144145-5
    ISSN 1873-0183 ; 1568-9972
    ISSN (online) 1873-0183
    ISSN 1568-9972
    DOI 10.1016/j.autrev.2021.103019
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5913: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Regulatory T Cells as an Escape Mechanism to the Immune Response in

    Adalid-Peralta, Laura / Lopez-Roblero, Alexander / Camacho-Vázquez, Cynthia / Nájera-Ocampo, Marisol / Guevara-Salinas, Adrián / Ruiz-Monroy, Nataly / Melo-Salas, Marlene / Morales-Ruiz, Valeria / López-Recinos, Dina / Ortiz-Hernández, Edgar / Demengeot, Jocelyne / Vazquez-Perez, Joel A / Arce-Sillas, Asiel / Gomez-Fuentes, Sandra / Parkhouse, Robert Michael Evans / Fragoso, Gladis / Sciutto, Edda / Sevilla-Reyes, Edgar E

    Frontiers in cellular and infection microbiology

    2021  Volume 11, Page(s) 630583

    Abstract: Murine cysticercosis ... ...

    Abstract Murine cysticercosis by
    MeSH term(s) Animals ; Immunity ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; T-Lymphocytes, Regulatory ; Taenia
    Language English
    Publishing date 2021-04-13
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2619676-1
    ISSN 2235-2988 ; 2235-2988
    ISSN (online) 2235-2988
    ISSN 2235-2988
    DOI 10.3389/fcimb.2021.630583
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: A novel, sequencing-free strategy for the functional characterization of Taenia solium proteomic fingerprint.

    Gomez-Fuentes, Sandra / Hernández-de la Fuente, Sarah / Morales-Ruiz, Valeria / López-Recinos, Dina / Guevara-Salinas, Adrián / Parada-Colin, María Cristina / Espitia, Clara / Ochoa-Leyva, Adrián / Sánchez, Filiberto / Villalobos, Nelly / Arce-Sillas, Asiel / Hernández, Marisela / Mora, Silvia Ivonne / Fragoso, Gladis / Sciutto, Edda / Adalid-Peralta, Laura

    PLoS neglected tropical diseases

    2021  Volume 15, Issue 2, Page(s) e0009104

    Abstract: The flatworm Taenia solium causes human and pig cysticercosis. When cysticerci are established in the human central nervous system, they cause neurocysticercosis, a potentially fatal disease. Neurocysticercosis is a persisting public health problem in ... ...

    Abstract The flatworm Taenia solium causes human and pig cysticercosis. When cysticerci are established in the human central nervous system, they cause neurocysticercosis, a potentially fatal disease. Neurocysticercosis is a persisting public health problem in rural regions of Mexico and other developing countries of Latin America, Asia, and Africa, where the infection is endemic. The great variability observed in the phenotypic and genotypic traits of cysticerci result in a great heterogeneity in the patterns of molecules secreted by them within their host. This work is aimed to identify and characterize cysticercal secretion proteins of T. solium cysticerci obtained from 5 naturally infected pigs from Guerrero, Mexico, using 2D-PAGE proteomic analysis. The isoelectric point (IP) and molecular weight (MW) of the spots were identified using the software ImageMaster 2D Platinum v.7.0. Since most secreted proteins are impossible to identify by mass spectrometry (MS) due to their low concentration in the sample, a novel strategy to predict their sequence was applied. In total, 108 conserved and 186 differential proteins were identified in five cysticercus cultures. Interestingly, we predicted the sequence of 14 proteins that were common in four out of five cysticercus cultures, which could be used to design vaccines or diagnostic methods for neurocysticercosis. A functional characterization of all sequences was performed using the algorithms SecretomeP, SignalP, and BlastKOALA. We found a possible link between signal transduction pathways in parasite cells and human cancer due to deregulation in signal transduction pathways. Bioinformatics analysis also demonstrated that the parasite release proteins by an exosome-like mechanism, which could be of biological interest.
    MeSH term(s) Animals ; Cysticercosis/veterinary ; Cysticercus/metabolism ; Electrophoresis, Gel, Two-Dimensional ; Helminth Proteins/genetics ; Helminth Proteins/isolation & purification ; Proteome ; Sequence Analysis, Protein ; Signal Transduction ; Swine ; Swine Diseases/parasitology ; Taenia solium/genetics ; Taenia solium/growth & development ; Taenia solium/metabolism
    Chemical Substances Helminth Proteins ; Proteome
    Language English
    Publishing date 2021-02-18
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2429704-5
    ISSN 1935-2735 ; 1935-2735
    ISSN (online) 1935-2735
    ISSN 1935-2735
    DOI 10.1371/journal.pntd.0009104
    Database MEDical Literature Analysis and Retrieval System OnLINE

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