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  1. Artikel: Development of Simple and Sensitive Score to Assess the Risk of Pneumonia in COVID-19 Patients.

    Hormanstorfer, Macarena / Ragusa, Martin A / Poggio, Lucia / Moreira-Facundo, Jorge / Orellana-Villa, Zulma / Bobrowski, Florencia A / Martinez-Serventi, Joaquin / Piombi Adanza, Santiago N / Enrique Barletta, Jose A / Sisto, Alicia / Delle-Piane, Hugo / Carrillo, Juan M / Presas, Jose L / Paulin, Francisco

    Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion

    2020  Band 73, Heft 1, Seite(n) 52–58

    Abstract: Background: Severe pneumonia is the most common cause of intensive care unit (ICU) admission and death due to novel coronavirus (SARS-CoV-2) respiratory disease (COVID-19). Due to its rapid outbreak, units for the evaluation of febrile patients in the ... ...

    Abstract Background: Severe pneumonia is the most common cause of intensive care unit (ICU) admission and death due to novel coronavirus (SARS-CoV-2) respiratory disease (COVID-19). Due to its rapid outbreak, units for the evaluation of febrile patients in the pre-hospital setting were created.
    Objective: The objective of the study was to develop a sensitive and simple tool to assess the risk of pneumonia in COVID-19 patients and thus select which patients would require a chest imaging study.
    Materials and methods: We conducted a cross-sectional study in a cohort of individuals with suspected COVID-19 evaluated in a public academic healthcare center in Buenos Aires city. All adult patients with positive RT-PCR assay for SARS-COV2 between April 24 and May 19 of 2020 were included in the study. Pneumonia was defined as the presence of compatible signs and symptoms with imaging confirmation. Univariate and multivariate logistic regression was performed. A risk indicator score was developed.
    Results: One hundred and forty-eight patients were included, 71 (48%) received the diagnosis of pneumonia. The final clinical model included four variables: age >- 40 years, cough, absence of sore throat, and respiratory rate >- 22. To create the score, we assigned values to the variables according to their ORs: 2 points for respiratory rate >- 22 and 1 point to the other variables. The AUC of the ROC curve was 0.80 (CI 95% 0.73-0.86). A cutoff value of 2 showed a sensitivity of 95.7% and a specificity of 43.24%.
    Conclusion: This sensible score may improve the risk stratification of COVID-19 patients in the pre-hospital setting.
    Mesh-Begriff(e) Adolescent ; Adult ; Argentina ; COVID-19/complications ; COVID-19/diagnosis ; Cohort Studies ; Cross-Sectional Studies ; Female ; Fever/diagnosis ; Fever/virology ; Humans ; Intensive Care Units ; Male ; Middle Aged ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/etiology ; Prospective Studies ; Reverse Transcriptase Polymerase Chain Reaction ; Risk ; Sensitivity and Specificity ; Severity of Illness Index ; Young Adult
    Schlagwörter covid19
    Sprache Englisch
    Erscheinungsdatum 2020-10-19
    Erscheinungsland Mexico
    Dokumenttyp Journal Article
    ZDB-ID 138348-6
    ISSN 0034-8376
    ISSN 0034-8376
    DOI 10.24875/RIC.20000295
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel: Development of Simple and Sensitive Score to Assess the Risk of Pneumonia in COVID-19 Patients

    Hormanstorfer, Macarena / Ragusa, Martin A / Poggio, Lucia / Moreira-Facundo, Jorge / Orellana-Villa, Zulma / Bobrowski, Florencia A / Martinez-Serventi, Joaquin / Piombi Adanza, Santiago N / Enrique Barletta, Jose A / Sisto, Alicia / Delle-Piane, Hugo / Carrillo, Juan M / Presas, Jose L / Paulin, Francisco

    Rev. invest. clin

    Abstract: BACKGROUND: Severe pneumonia is the most common cause of intensive care unit (ICU) admission and death due to novel coronavirus (SARS-CoV-2) respiratory disease (COVID-19). Due to its rapid outbreak, units for the evaluation of febrile patients in the ... ...

    Abstract BACKGROUND: Severe pneumonia is the most common cause of intensive care unit (ICU) admission and death due to novel coronavirus (SARS-CoV-2) respiratory disease (COVID-19). Due to its rapid outbreak, units for the evaluation of febrile patients in the pre-hospital setting were created. OBJECTIVE: The objective of the study was to develop a sensitive and simple tool to assess the risk of pneumonia in COVID-19 patients and thus select which patients would require a chest imaging study. MATERIALS AND METHODS: We conducted a cross-sectional study in a cohort of individuals with suspected COVID-19 evaluated in a public academic healthcare center in Buenos Aires city. All adult patients with positive RT-PCR assay for SARS-COV2 between April 24 and May 19 of 2020 were included in the study. Pneumonia was defined as the presence of compatible signs and symptoms with imaging confirmation. Univariate and multivariate logistic regression was performed. A risk indicator score was developed. RESULTS: One hundred and forty-eight patients were included, 71 (48%) received the diagnosis of pneumonia. The final clinical model included four variables: age >- 40 years, cough, absence of sore throat, and respiratory rate >- 22. To create the score, we assigned values to the variables according to their ORs: 2 points for respiratory rate >- 22 and 1 point to the other variables. The AUC of the ROC curve was 0.80 (CI 95% 0.73-0.86). A cutoff value of 2 showed a sensitivity of 95.7% and a specificity of 43.24%. CONCLUSION: This sensible score may improve the risk stratification of COVID-19 patients in the pre-hospital setting.
    Schlagwörter covid19
    Verlag WHO
    Dokumenttyp Artikel
    Anmerkung WHO #Covidence: #875093
    Datenquelle COVID19

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