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  1. Artikel ; Online: Corrigendum to

    Moreno, E / Ortega, M S / Pohler, K G

    Reproduction, fertility, and development

    2024  Band 36, Heft 3, Seite(n) NULL

    Sprache Englisch
    Erscheinungsdatum 2024-01-25
    Erscheinungsland Australia
    Dokumenttyp Journal Article
    ZDB-ID 1019913-5
    ISSN 1448-5990 ; 1031-3613
    ISSN (online) 1448-5990
    ISSN 1031-3613
    DOI 10.1071/RDv36n2Ab65_CO
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  2. Artikel: Evaluation of Consumption of Poultry Products Enriched with Omega-3 Fatty Acids in Anthropometric, Biochemical, and Cardiovascular Parameters

    Ramirez Moreno, Esther / Añorve-Morga, Javier

    Journal of food quality, 2018:9620104

    2018  

    Abstract: An alternative for prevention and treatment for cardiovascular diseases (CVD) is increasing the intake of bioactive compounds as omega-3. However, several countries as México do not consume regularly foods with high content of omega-3, mainly fish ... ...

    Abstract An alternative for prevention and treatment for cardiovascular diseases (CVD) is increasing the intake of bioactive compounds as omega-3. However, several countries as México do not consume regularly foods with high content of omega-3, mainly fish products due to cultural, social, and economic factors. Therefore, the addition of omega-3 in other food sources could contribute to completing the requirements established of these fatty acids. To evaluate the effect of the consumption of poultry products supplemented with omega-3 in healthy population, a phase 1, double blind randomized, controlled parallel-group trial was carried out. After 14 weeks, the supplemented group had an increase in HDL, reducing the atherogenic index. The supplementation with omega-3 in poultry products could contribute to a cardioprotective effect. It is necessary to complete studies with a higher evaluation period to determine the improvement in anthropometric and cardiovascular parameters.
    Sprache Englisch
    Dokumenttyp Artikel
    Datenquelle Fachrepositorium Lebenswissenschaften

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  3. Artikel ; Online: The one hundred year journey of the genus Brucella (Meyer and Shaw 1920).

    Moreno, Edgardo

    FEMS microbiology reviews

    2020  Band 45, Heft 1

    Abstract: The genus Brucella, described by Meyer and Shaw in 1920, comprises bacterial pathogens of veterinary and public health relevance. For 36 years, the genus came to include three species that caused brucellosis in livestock and humans. In the second half of ...

    Abstract The genus Brucella, described by Meyer and Shaw in 1920, comprises bacterial pathogens of veterinary and public health relevance. For 36 years, the genus came to include three species that caused brucellosis in livestock and humans. In the second half of the 20th century, bacteriologists discovered five new species and several 'atypical' strains in domestic animals and wildlife. In 1990, the Brucella species were recognized as part of the Class Alphaproteobacteria, clustering with pathogens and endosymbionts of animals and plants such as Bartonella, Agrobacterium and Ochrobactrum; all bacteria that live in close association with eukaryotic cells. Comparisons with Alphaproteobacteria contributed to identify virulence factors and to establish evolutionary relationships. Brucella members have two circular chromosomes, are devoid of plasmids, and display close genetic relatedness. A proposal, asserting that all brucellae belong to a single species with several subspecies debated for over 70 years, was ultimately rejected in 2006 by the subcommittee of taxonomy, based on scientific, practical, and biosafety considerations. Following this, the nomenclature of having multiples Brucella species prevailed and defined according to their molecular characteristics, host preference, and virulence. The 100-year history of the genus corresponds to the chronicle of scientific efforts and the struggle for understanding brucellosis.
    Mesh-Begriff(e) Animals ; Brucella/classification ; Brucella/genetics ; Brucella/pathogenicity ; Brucellosis/microbiology ; Host Specificity ; Humans ; Terminology as Topic ; Virulence Factors/genetics
    Chemische Substanzen Virulence Factors
    Sprache Englisch
    Erscheinungsdatum 2020-10-04
    Erscheinungsland England
    Dokumenttyp Journal Article ; Review
    ZDB-ID 283740-7
    ISSN 1574-6976 ; 0168-6445
    ISSN (online) 1574-6976
    ISSN 0168-6445
    DOI 10.1093/femsre/fuaa045
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  4. Artikel ; Online: Changes in resource perception throughout the foraging visit contribute to task specialization in the honey bee Apis mellifera.

    Moreno, Emilia / Arenas, Andrés

    Scientific reports

    2023  Band 13, Heft 1, Seite(n) 8164

    Abstract: Division of labor is central to the ecological success of social insects. Among foragers of the honey bee, specialization for collecting nectar or pollen correlates with their sensitivity to sucrose. So far, differences in gustatory perception have been ... ...

    Abstract Division of labor is central to the ecological success of social insects. Among foragers of the honey bee, specialization for collecting nectar or pollen correlates with their sensitivity to sucrose. So far, differences in gustatory perception have been mostly studied in bees returning to the hive, but not during foraging. Here, we showed that the phase of the foraging visit (i.e. beginning or end) interacts with foraging specialization (i.e. predisposition to collect pollen or nectar) to modulate sucrose and pollen sensitivity in foragers. In concordance with previous studies, pollen foragers presented higher sucrose responsiveness than nectar foragers at the end of the foraging visit. On the contrary, pollen foragers were less responsive than nectar foragers at the beginning of the visit. Consistently, free-flying foragers accepted less concentrated sucrose solution during pollen gathering than immediately after entering the hive. Pollen perception also changes throughout foraging, as pollen foragers captured at the beginning of the visit learned and retained memories better when they were conditioned with pollen + sucrose as reward than when we used sucrose alone. Altogether, our results support the idea that changes in foragers' perception throughout the foraging visit contributes to task specialization.
    Mesh-Begriff(e) Bees ; Animals ; Feeding Behavior ; Plant Nectar ; Sucrose ; Learning ; Taste Perception
    Chemische Substanzen Plant Nectar ; Sucrose (57-50-1)
    Sprache Englisch
    Erscheinungsdatum 2023-05-19
    Erscheinungsland England
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-35163-y
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  5. Artikel ; Online: In Vitro Cell Transformation Assays: A Valuable Approach for Carcinogenic Potentiality Assessment of Nanomaterials.

    Chatterjee, Nivedita / Alfaro-Moreno, Ernesto

    International journal of molecular sciences

    2023  Band 24, Heft 9

    Abstract: This review explores the application of in vitro cell transformation assays (CTAs) as a screening platform to assess the carcinogenic potential of nanomaterials (NMs) resulting from continuously growing industrial production and use. The widespread ... ...

    Abstract This review explores the application of in vitro cell transformation assays (CTAs) as a screening platform to assess the carcinogenic potential of nanomaterials (NMs) resulting from continuously growing industrial production and use. The widespread application of NMs in various fields has raised concerns about their potential adverse effects, necessitating safety evaluations, particularly in long-term continuous exposure scenarios. CTAs present a realistic screening platform for known and emerging NMs by examining their resemblance to the hallmark of malignancy, including high proliferation rates, loss of contact inhibition, the gain of anchorage-independent growth, cellular invasion, dysregulation of the cell cycle, apoptosis resistance, and ability to form tumors in experimental animals. Through the deliberate transformation of cells via chronic NM exposure, researchers can investigate the tumorigenic properties of NMs and the underlying mechanisms of cancer development. This article examines NM-induced cell transformation studies, focusing on identifying existing knowledge gaps. Specifically, it explores the physicochemical properties of NMs, experimental models, assays, dose and time requirements for cell transformation, and the underlying mechanisms of malignancy. Our review aims to advance understanding in this field and identify areas for further investigation.
    Mesh-Begriff(e) Animals ; Carcinogens/toxicity ; Carcinogenesis/chemically induced ; Cell Transformation, Neoplastic/chemically induced ; Nanostructures/toxicity ; Nanostructures/chemistry ; Neoplasms
    Chemische Substanzen Carcinogens
    Sprache Englisch
    Erscheinungsdatum 2023-05-04
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms24098219
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  6. Artikel: Organic Acids, Antioxidants, and Dietary Fiber of Mexican Blackberry (Rubus fruticosus) Residues cv. Tupy

    Cruz-Cansino, Nelly / Añorve-Morga, Javier / Castañeda-Ovando, Araceli / Ramirez Moreno, Esther

    Journal of food quality, 2018:5950761

    2018  

    Abstract: Blackberry fruit processing generates residues comprised of peel, seeds, and pulp that are abundant in flavonoids, colorants, and organic acids. The objective of this study was to determine the organic acids, antioxidants, and dietary fiber content of ... ...

    Abstract Blackberry fruit processing generates residues comprised of peel, seeds, and pulp that are abundant in flavonoids, colorants, and organic acids. The objective of this study was to determine the organic acids, antioxidants, and dietary fiber content of blackberry residues and compare antioxidants and dietary fiber content of a prune-based commercial product. The ABTS, DPPH, and FRAP methodologies were used for antioxidant capacity. The blackberry residues exhibited a high amount of malic acid (5706.37 mg/100 g db), phenols (4016.43 mg GAE/100 g db), and anthocyanins content (364.53 mg/100 g db) compared with the commercial product. These compounds contributed to the antioxidant capacity (by ABTS) of both products but were 20 times higher in blackberry residues. The fruit residues were able to reduce iron (by FRAP) 4.4 times compared to the prune-based product. Total dietary fiber (44.26%) and functional properties as water retention capacity (2.94 g/g), swelling capacity (5.00 mL/g), and fat absorption capacity (1.98 mL/g) of blackberry residues were significantly higher than those of the commercial sample. The results demonstrated that, due to its antioxidant compounds and functional properties, the blackberry residue can be considered a source of components with potential benefit to human health.
    Sprache Englisch
    Dokumenttyp Artikel
    Datenquelle Fachrepositorium Lebenswissenschaften

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  7. Artikel ; Online: The geodynamic origin of Los Humeros volcanic field in Mexico: insights from numerical simulations.

    Bayona, A / Manea, V C / Manea, M / Yoshioka, S / Moreno, E / Suenaga, N

    Scientific reports

    2023  Band 13, Heft 1, Seite(n) 22284

    Abstract: Compared to normal arc-related volcanic eruptions, the formation of a volcanic caldera is a relatively atypical event. During caldera formation a series of large volumes of magma are erupted, reducing the structural support for the rock above the magma ... ...

    Abstract Compared to normal arc-related volcanic eruptions, the formation of a volcanic caldera is a relatively atypical event. During caldera formation a series of large volumes of magma are erupted, reducing the structural support for the rock above the magma chamber and creating a large depression at the surface called caldera. Los Humeros volcanic field (LHVF) represents one of the largest volcanic calderas in Mexico. It is located some 400 km from the trench at the eastern edge of the Trans Mexican Volcanic Belt where the depth to the Cocos slab is more than 300 km. In this study we employ high-resolution two-dimensional thermomechanical numerical simulations of magma intrusions and a horizontal tectonic strain rate to better understand the influence of crustal deformation for the formation of Los Humeros caldera. A minimum number of three thermal anomaly pulses of hydrated mantle material (with diameter of 15 km or more) and a regional strain rate of 7.927 × 10
    Sprache Englisch
    Erscheinungsdatum 2023-12-14
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-49292-x
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  8. Artikel ; Online: Unilateral cerebral amyloid angiopathy after neurointervention.

    Lázaro Romero, A / Moreno Loscertales, C / Marta Moreno, E

    Neurologia (Barcelona, Spain)

    2022  Band 37, Heft 4, Seite(n) 310–312

    Mesh-Begriff(e) Cerebral Amyloid Angiopathy/complications ; Cerebral Amyloid Angiopathy/diagnostic imaging ; Humans
    Sprache Englisch
    Erscheinungsdatum 2022-04-22
    Erscheinungsland Spain
    Dokumenttyp Letter
    ZDB-ID 2654369-2
    ISSN 2173-5808 ; 2173-5808
    ISSN (online) 2173-5808
    ISSN 2173-5808
    DOI 10.1016/j.nrleng.2021.05.009
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  9. Artikel ; Online: A review of three decades of use of the cattle brucellosis rough vaccine Brucella abortus RB51: myths and facts.

    Blasco, J M / Moreno, E / Muñoz, P M / Conde-Álvarez, R / Moriyón, I

    BMC veterinary research

    2023  Band 19, Heft 1, Seite(n) 211

    Abstract: Cattle brucellosis is a severe zoonosis of worldwide distribution caused by Brucella abortus and B. melitensis. In some countries with appropriate infrastructure, animal tagging and movement control, eradication was possible through efficient diagnosis ... ...

    Abstract Cattle brucellosis is a severe zoonosis of worldwide distribution caused by Brucella abortus and B. melitensis. In some countries with appropriate infrastructure, animal tagging and movement control, eradication was possible through efficient diagnosis and vaccination with B. abortus S19, usually combined with test-and-slaughter (T/S). Although S19 elicits anti-smooth lipopolysaccharide antibodies that may interfere in the differentiation of infected and vaccinated animals (DIVA), this issue is minimized using appropriate S19 vaccination protocols and irrelevant when high-prevalence makes mass vaccination necessary or when eradication requisites are not met. However, S19 has been broadly replaced by vaccine RB51 (a rifampin-resistant rough mutant) as it is widely accepted that is DIVA, safe and as protective as S19. These RB51 properties are critically reviewed here using the evidence accumulated in the last 35 years. Controlled experiments and field evidence shows that RB51 interferes in immunosorbent assays (iELISA, cELISA and others) and in complement fixation, issues accentuated by revaccinating animals previously immunized with RB51 or S19. Moreover, contacts with virulent brucellae elicit anti-smooth lipopolysaccharide antibodies in RB51 vaccinated animals. Thus, accepting that RB51 is truly DIVA results in extended diagnostic confusions and, when combined with T/S, unnecessary over-culling. Studies supporting the safety of RB51 are flawed and, on the contrary, there is solid evidence that RB51 is excreted in milk and abortifacient in pregnant animals, thus being released in abortions and vaginal fluids. These problems are accentuated by the RB51 virulence in humans, lack diagnostic serological tests detecting these infections and RB51 rifampicin resistance. In controlled experiments, protection by RB51 compares unfavorably with S19 and lasts less than four years with no evidence that RB51-revaccination bolsters immunity, and field studies reporting its usefulness are flawed. There is no evidence that RB51 protects cattle against B. melitensis, infection common when raised together with small ruminants. Finally, data acumulated during cattle brucellosis eradication in Spain shows that S19-T/S is far more efficacious than RB51-T/S, which does not differ from T/S alone. We conclude that the assumption that RB51 is DIVA, safe, and efficaceous results from the uncritical repetition of imperfectly examined evidence, and advise against its use.
    Mesh-Begriff(e) Pregnancy ; Female ; Humans ; Cattle ; Animals ; Brucella abortus ; Brucellosis/veterinary ; Lipopolysaccharides ; Brucella Vaccine ; Abortion, Veterinary ; Vaccination/veterinary ; Antibodies, Bacterial ; Cattle Diseases
    Chemische Substanzen Lipopolysaccharides ; Brucella Vaccine ; Antibodies, Bacterial
    Sprache Englisch
    Erscheinungsdatum 2023-10-18
    Erscheinungsland England
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2191675-5
    ISSN 1746-6148 ; 1746-6148
    ISSN (online) 1746-6148
    ISSN 1746-6148
    DOI 10.1186/s12917-023-03773-3
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  10. Artikel: Dupilumab: A Review of Present Indications and Off-Label Uses.

    Muñoz-Bellido, F J / Moreno, E / Dávila, I

    Journal of investigational allergology & clinical immunology

    2021  Band 32, Heft 2, Seite(n) 97–115

    Abstract: Recent advances in our understanding of T2 inflammation have revealed more diseases in which T2 inflammation is involved. Dupilumab is a recently developed monoclonal antibody that blocks signaling of IL-4 and IL-13, both of which are crucial cytokines ... ...

    Abstract Recent advances in our understanding of T2 inflammation have revealed more diseases in which T2 inflammation is involved. Dupilumab is a recently developed monoclonal antibody that blocks signaling of IL-4 and IL-13, both of which are crucial cytokines in the T2 response. New possible indications are increasingly explored and include skin diseases, such as prurigo nodularis, nummular eczema, allergic contact dermatitis, chronic hand eczema, spontaneous chronic urticaria, bullous pemphigoid, alopecia areata, and Netherton syndrome, as well as respiratory diseases, such as allergic bronchopulmonary aspergillosis, chronic eosinophilic pneumonia, and allergic rhinitis. In addition, eosinophilic gastrointestinal disorders, particularly eosinophilic esophagitis, and food allergy, are also research fields of interest. Here, we review published data and clinical trials examining the use of dupilumab in these disorders.
    Mesh-Begriff(e) Antibodies, Monoclonal, Humanized/therapeutic use ; Eczema/drug therapy ; Humans ; Inflammation ; Off-Label Use
    Chemische Substanzen Antibodies, Monoclonal, Humanized ; dupilumab (420K487FSG)
    Sprache Englisch
    Erscheinungsdatum 2021-03-03
    Erscheinungsland Spain
    Dokumenttyp Journal Article ; Review
    ZDB-ID 1128657-x
    ISSN 1018-9068
    ISSN 1018-9068
    DOI 10.18176/jiaci.0682
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