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  1. Artikel ; Online: PRESCRIBING PATTERNS AND THE USE OF ANTHELMINTIC DRUGS IN COLOMBIAN PATIENTS: A CROSS-SECTIONAL STUDY.

    Montes-Montoya, Maria Camila / Gaviria-Mendoza, Andrés / Murillo-Muñoz, Maria Mónica / Cardona-Ospina, Jaime Andrés / Machado-Alba, Jorge Enrique

    The Journal of parasitology

    2023  Band 109, Heft 6, Seite(n) 537–542

    Abstract: Intestinal parasites continue to be a public health problem in low- and middle-income countries. Broad use of anthelmintics during deworming programs is still necessary in many regions. However, description of the usage of these medications in general ... ...

    Abstract Intestinal parasites continue to be a public health problem in low- and middle-income countries. Broad use of anthelmintics during deworming programs is still necessary in many regions. However, description of the usage of these medications in general medical practice has been limited. The objective of this study was to determine the use of anthelmintic drugs and their indications in a group of Colombian patients. This was a descriptive study from a drug-dispensing database, identifying patients with prescriptions for anthelmintic drugs. A total of 381 cases were randomly selected, and their medical records were reviewed, analyzing sociodemographic, clinical, and pharmacological variables (indication of use). The lack of diagnosis registration or clinical manifestations of parasites was determined as a prescription without indication. In total, 50.9% (n = 194) of patients were female, and 67.4% of all patients were under 18 yr of age. The diagnosis of helminthiases was clearly stated in 114 (29.9%) patients, and only 4.2% (n = 16) of these had microbiological confirmation. The most commonly used anthelmintic drug was albendazole (70.4% of all prescriptions). The use of anthelmintics was not indicated in 266 cases (69.8%). Nutritional supplements or vitamin prescriptions were associated with using anthelmintics without indication (odds ratio: 2.25; 95% confidence interval: 1.26-4.03). A high proportion of patients lacked symptoms or diagnoses in their clinical records that supported the use of anthelmintic drugs.
    Mesh-Begriff(e) Adolescent ; Adult ; Child ; Female ; Humans ; Male ; Albendazole/therapeutic use ; Anthelmintics/therapeutic use ; Colombia/epidemiology ; Cross-Sectional Studies ; Helminthiasis/drug therapy ; Helminthiasis/epidemiology
    Chemische Substanzen Albendazole (F4216019LN) ; Anthelmintics
    Sprache Englisch
    Erscheinungsdatum 2023-11-08
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 300870-8
    ISSN 1937-2345 ; 0022-3395
    ISSN (online) 1937-2345
    ISSN 0022-3395
    DOI 10.1645/22-8
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Potential prescribing omissions in patients with cardiovascular disease.

    Murillo-Muñoz, María Mónica / Gaviria-Mendoza, Andrés / Machado-Alba, Jorge Enrique

    International journal of clinical practice

    2019  , Seite(n) e13428

    Abstract: Aims Potential prescribing omissions (PPOs) of medications are a frequent form of inadequate prescription drug practices. The objective of this study was to identify PPOs in a sample of elderly patients with cardiovascular disease. Methods Quasi- ... ...

    Abstract Aims Potential prescribing omissions (PPOs) of medications are a frequent form of inadequate prescription drug practices. The objective of this study was to identify PPOs in a sample of elderly patients with cardiovascular disease. Methods Quasi-experimental study. Data were collected from a population database. We included patients who were older than 65 years and had a diagnosis of hypertension, dyslipidaemia, diabetes mellitus, coronary heart disease, heart failure or atrial fibrillation in Colombia. PPOs were determined in a random sample of patients by the START-2 (Screening Tool to Alert doctors to Right Treatment) criteria. The impact of the PPO was determined after an educational intervention with the doctors who were responsible for treating said patients. Results A total of 630 patients, with a median age of 72 years (interquartile range: 68-78 years), were included; 56.2% were women. The most frequent diagnoses were arterial hypertension (94.1%, n = 593) and dyslipidaemia (56.5%, n = 356). We identified 100 patients (15.9%) with omissions equalling 139 PPOs, and the most common PPOs were due to a lack of angiotensin-converting enzyme inhibitors in patients associated with heart failure or coronary heart disease (n = 23, 16.5%) and a lack of statins (n = 20; 14.4%) and aspirin (n = 20; 14.4%) in coronary heart disease. Prescription adjustments were achieved in 35 patients (25.2%). Conclusions Potential prescribing omissions are common in elderly patients with cardiovascular disease. Educational interventions may contribute to a reduced PPO frequency and improve the quality of prescription drug administration.
    Sprache Englisch
    Erscheinungsdatum 2019-10-01
    Erscheinungsland India
    Dokumenttyp Journal Article
    ZDB-ID 1386246-7
    ISSN 1742-1241 ; 1368-5031
    ISSN (online) 1742-1241
    ISSN 1368-5031
    DOI 10.1111/ijcp.13428
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Trends in Opioid Use in a Cohort of Patients with Rheumatoid Arthritis.

    Machado-Duque, Manuel E / Ramírez-Valencia, Diana Marcela / Murillo-Muñoz, María Mónica / Machado-Alba, Jorge E

    Pain research & management

    2020  Band 2020, Seite(n) 3891436

    Abstract: The objective was to determine the trend in the use of opioid analgesics in a cohort of patients diagnosed with and treated for rheumatoid arthritis (RA) in 24 cities in Colombia. This retrospective cohort study included adult patients diagnosed with RA, ...

    Abstract The objective was to determine the trend in the use of opioid analgesics in a cohort of patients diagnosed with and treated for rheumatoid arthritis (RA) in 24 cities in Colombia. This retrospective cohort study included adult patients diagnosed with RA, which was managed in a specialized institution in Colombia between January 2011 and December 2012. The first rheumatology visit was recorded as an index date, and monthly monitoring of the analgesic medication received was performed until December 2017. Sociodemographic variables, the use of opioids, and concomitant prescriptions were evaluated. A total of 1,329 patients diagnosed with and treated for RA were included; they had a mean age of 61.2 ± 11.8 years and were predominantly females (
    Mesh-Begriff(e) Adult ; Aged ; Analgesics, Opioid/therapeutic use ; Anti-Inflammatory Agents, Non-Steroidal/therapeutic use ; Antirheumatic Agents/therapeutic use ; Arthritis, Rheumatoid/drug therapy ; Cohort Studies ; Colombia ; Female ; Humans ; Male ; Middle Aged ; Retrospective Studies
    Chemische Substanzen Analgesics, Opioid ; Anti-Inflammatory Agents, Non-Steroidal ; Antirheumatic Agents
    Sprache Englisch
    Erscheinungsdatum 2020-07-16
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 2041085-2
    ISSN 1918-1523 ; 1203-6765
    ISSN (online) 1918-1523
    ISSN 1203-6765
    DOI 10.1155/2020/3891436
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel ; Online: Gastroenterologists, Hepatologists, COVID-19 and the Use of Acetaminophen.

    Rodríguez-Morales, Alfonso J / Cardona-Ospina, Jaime A / Murillo-Muñoz, Maria Mónica

    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

    2020  Band 18, Heft 9, Seite(n) 2142–2143

    Mesh-Begriff(e) Acetaminophen ; Betacoronavirus ; COVID-19 ; Coronavirus Infections ; Gastroenterologists ; Humans ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2
    Chemische Substanzen Acetaminophen (362O9ITL9D)
    Schlagwörter covid19
    Sprache Englisch
    Erscheinungsdatum 2020-05-07
    Erscheinungsland United States
    Dokumenttyp Letter ; Comment
    ZDB-ID 2119789-1
    ISSN 1542-7714 ; 1542-3565
    ISSN (online) 1542-7714
    ISSN 1542-3565
    DOI 10.1016/j.cgh.2020.04.025
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel: Gastroenterologists, Hepatologists, COVID-19 and the Use of Acetaminophen

    Rodríguez-Morales, Alfonso J / Cardona-Ospina, Jaime A / Murillo-Muñoz, Maria Mónica

    Clin Gastroenterol Hepatol

    Schlagwörter covid19
    Verlag WHO
    Dokumenttyp Artikel
    Anmerkung WHO #Covidence: #197834
    Datenquelle COVID19

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  6. Artikel ; Online: Gastroenterologists, Hepatologists, COVID-19 and the Use of Acetaminophen

    Rodríguez-Morales, Alfonso J. / Cardona-Ospina, Jaime A. / Murillo-Muñoz, Maria Mónica

    Clinical Gastroenterology and Hepatology

    2020  Band 18, Heft 9, Seite(n) 2142–2143

    Schlagwörter Hepatology ; Gastroenterology ; covid19
    Sprache Englisch
    Verlag Elsevier BV
    Erscheinungsland us
    Dokumenttyp Artikel ; Online
    ZDB-ID 2119789-1
    ISSN 1542-7714 ; 1542-3565
    ISSN (online) 1542-7714
    ISSN 1542-3565
    DOI 10.1016/j.cgh.2020.04.025
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  7. Artikel ; Online: Effectiveness of lipid-lowering therapy among a sample of patients in Colombia.

    Machado-Alba, Jorge Enrique / Murillo-Muñoz, Maria Monica / Machado-Duque, Manuel Enrique

    Revista panamericana de salud publica = Pan American journal of public health

    2013  Band 33, Heft 6, Seite(n) 383–390

    Abstract: Objective: To determine the effectiveness of lipid-lowering therapy in a sample of patients affiliated with the Sistema General de Seguridad Social en Salud (the Colombian health system).: Methods: A cross-sectional study was conducted from 1 January ...

    Abstract Objective: To determine the effectiveness of lipid-lowering therapy in a sample of patients affiliated with the Sistema General de Seguridad Social en Salud (the Colombian health system).
    Methods: A cross-sectional study was conducted from 1 January 2010-30 June 2011. From a total of 8 316 patients in 10 cities, a random sample of 600 was stratified according to dyslipidemia. Information on sociodemographic and anthropometric characteristics, risk factors, and pharmacological and laboratory variables were obtained from medical records.
    Results: Subjects were predominantly female (56.2%), with a mean age of 65.1 ± 11.5 years; 93.2% had hypertension; 29.0%, diabetes mellitus; and 10.2%, a history of myocardial infarction. The patients were being treated with lovastatin (84.1%) or gemfibrozil (12.3%)-both at doses below what is recommended-or atorvastatin (1.8%). In patients with high cardiovascular risk, 38.6% achieved goals for low-density lipoprotein cholesterol (LDL-C) levels (<100 mg/dL). Among those at moderate risk, 49.4% reached the target level (< 130 mg/dL). On average, there was a 4.9% reduction in LDL-C. Sex, age, history of cardiovascular disease and/or diabetes mellitus, use of hydrochlorothiazide, and poor therapy adherence were statistically associated with a lack of dyslipidemia control.
    Conclusions: Because a lack LDL-C control occurred in patients with two or more of the following variables: male, more than 55 years of age, diabetes and/or a history of cardiovascular disease, received lower doses of lovastatin, or non-adherent to treatment, it is recommended that medication be increased based on clearly-defined therapeutic goals and that comorbidities be assessed and effectively treated.
    Mesh-Begriff(e) Aged ; Colombia ; Cross-Sectional Studies ; Dyslipidemias/drug therapy ; Female ; Humans ; Hypolipidemic Agents/therapeutic use ; Male ; Retrospective Studies ; Treatment Outcome
    Chemische Substanzen Hypolipidemic Agents
    Sprache Englisch
    Erscheinungsdatum 2013-06-25
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1376934-0
    ISSN 1680-5348 ; 1020-4989
    ISSN (online) 1680-5348
    ISSN 1020-4989
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Buch ; Artikel ; Online: Effectiveness of lipid-lowering therapy among a sample of patients in Colombia

    Machado-Alba, Jorge Enrique / Murillo-Muñoz, Maria Monica / Machado-Duque, Manuel Enrique

    2015  

    Schlagwörter Dyslipidemia ; Anticholesteremic Agents ; Efficacy ; Cardiovascular Diseases ; Lovastatin ; Gemfibrozil ; Colombia ; Dislipidemias ; Anticolesterolemiantes ; Enfermedades Cardiovasculares ; Lovastatina ; Gemfibrozilo ; Hipolipemiantes ; Colômbia ; Estudos Transversais ; Estudos Retrospectivos ; Resultado do Tratamento
    Erscheinungsdatum 2015-08-25T14:54:59Z
    Dokumenttyp Buch ; Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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