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  1. Buch ; Online: Neurorehabilitation: Looking Back and Moving Forward

    Nasios, Grigorios / Messinis, Lambros / Dardiotis, Efthimios / Sgantzos, Markos

    2023  

    Schlagwörter Research & information: general ; Biology, life sciences ; Biochemistry ; Covid-19 ; telerehabilitation ; post-stroke rehabilitation ; virtual reality ; stroke ; percutaneous electric nerve stimulation ; transcutaneous electric nerve stimulation ; adult ; urinary bladder ; overactive ; urinary incontinence ; tibial nerve ; multiple sclerosis ; employment ; patient-reported outcome ; MSWDQ-23 ; validation ; rTMS ; dementia ; Alzheimer's disease ; magnetic stimulation ; non-pharmacological treatments ; refractory temporal seizures ; neurosurgery ; cognitive outcome ; memory ; long-term follow-up ; backward walking ; balance ; cerebral palsy ; mental motor imagery ; neurorehabilitation ; cost-utility ; upper extremity ; EQ-5D ; cognitive exercise therapy ; sensorimotor ; activity of daily living ; Parkinson's disease ; salivation ; clinical features ; non-motor ; motor ; sialorrhea ; drooling ; oxidative stress ; antioxidant defense ; Oxidative Status Index (OSI) ; hydroperoxides ; rehabilitation ; n/a
    Sprache Englisch
    Umfang 1 electronic resource (162 pages)
    Verlag MDPI - Multidisciplinary Digital Publishing Institute
    Erscheinungsort Basel
    Dokumenttyp Buch ; Online
    Anmerkung English
    HBZ-ID HT030374745
    ISBN 9783036578606 ; 3036578609
    Datenquelle ZB MED Katalog Medizin, Gesundheit, Ernährung, Umwelt, Agrar

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  2. Artikel: Detection and Prevention of Mild Cognitive Impairment and Dementia.

    Messinis, Lambros / Nasios, Grigorios / Ioannidis, Panagiotis / Patrikelis, Panayiotis

    Healthcare (Basel, Switzerland)

    2023  Band 11, Heft 16

    Abstract: Mild cognitive impairment (MCI) is characterized by cognitive deficits alongside essentially preserved competence in activities of daily living [ ... ]. ...

    Abstract Mild cognitive impairment (MCI) is characterized by cognitive deficits alongside essentially preserved competence in activities of daily living [...].
    Sprache Englisch
    Erscheinungsdatum 2023-08-08
    Erscheinungsland Switzerland
    Dokumenttyp Editorial
    ZDB-ID 2721009-1
    ISSN 2227-9032
    ISSN 2227-9032
    DOI 10.3390/healthcare11162232
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel: Neurorehabilitation: Looking Back and Moving Forward, 1st Edition.

    Nasios, Grigorios / Messinis, Lambros / Dardiotis, Efthimios / Sgantzos, Markos

    Healthcare (Basel, Switzerland)

    2023  Band 11, Heft 10

    Abstract: Rehabilitation is "a set of interventions designed to optimize functioning and reduce disability in individuals with health conditions in interaction with their environment", according to the recent report from the World Health Organization (WHO), ... ...

    Abstract Rehabilitation is "a set of interventions designed to optimize functioning and reduce disability in individuals with health conditions in interaction with their environment", according to the recent report from the World Health Organization (WHO), released in January 2023 [...].
    Sprache Englisch
    Erscheinungsdatum 2023-05-17
    Erscheinungsland Switzerland
    Dokumenttyp Editorial
    ZDB-ID 2721009-1
    ISSN 2227-9032
    ISSN 2227-9032
    DOI 10.3390/healthcare11101452
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel ; Online: Undetected language deficits in left or right hemisphere post-stroke patients.

    Martzoukou, Maria / Nousia, Anastasia / Nasios, Grigorios

    Applied neuropsychology. Adult

    2023  , Seite(n) 1–9

    Abstract: Previous studies have reported that widely used tests for aphasia identification are unable to detect the subtle language deficits of left hemisphere brain damaged (LHBD) individuals. Similarly, the language disorders of individuals with right hemisphere ...

    Abstract Previous studies have reported that widely used tests for aphasia identification are unable to detect the subtle language deficits of left hemisphere brain damaged (LHBD) individuals. Similarly, the language disorders of individuals with right hemisphere brain damage (RHBD) usually remain undetected, due to the lack of any specialized test for the evaluation of their language processing skills. The aim of the present study was to evaluate the language deficits of 80 individuals suffering from the effects of either a LHBD or RHBD stroke, who were diagnosed as having no aphasia or language deficits based on the application of Boston Diagnostic Aphasia Examination. Their language abilities were examined with the use of the Adults' Language Abilities Test, which explores morpho-syntactic and semantic phenomena of the Greek language in both the comprehension and production modalities. Results revealed that both groups of stroke survivors performed significantly worse compared to the group of healthy participants. Thus, it appears that the latent aphasia of LHBD and the language deficits of RHBD patients are likely to remain undetected and that patients are at risk of not receiving appropriate treatment if their language abilities are not evaluated by an effective and efficient battery of language tests.
    Sprache Englisch
    Erscheinungsdatum 2023-03-30
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 2673736-X
    ISSN 2327-9109 ; 2327-9095
    ISSN (online) 2327-9109
    ISSN 2327-9095
    DOI 10.1080/23279095.2023.2195111
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Volltext online

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  5. Artikel: Alzheimer Disease and HIV: Untangling the Gordian Knot.

    Messinis, Lambros / Nasios, Grigorios

    Neurology. Clinical practice

    2021  Band 11, Heft 5, Seite(n) 365–366

    Sprache Englisch
    Erscheinungsdatum 2021-11-18
    Erscheinungsland United States
    Dokumenttyp Editorial
    ZDB-ID 2645818-4
    ISSN 2163-0933 ; 2163-0402
    ISSN (online) 2163-0933
    ISSN 2163-0402
    DOI 10.1212/CPJ.0000000000001102
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel ; Online: Cognitive trajectories preluding the onset of different dementia entities: a descriptive longitudinal study using the NACC database.

    Liampas, Ioannis / Dimitriou, Nefeli / Siokas, Vasileios / Messinis, Lambros / Nasios, Grigorios / Dardiotis, Efthimios

    Aging clinical and experimental research

    2024  Band 36, Heft 1, Seite(n) 119

    Abstract: Objective: To describe the 10-year preclinical cognitive trajectories of older, non-demented individuals towards the onset of the four most prevalent types of dementia, i.e., Alzheimer's disease(AD), Lewy body(LBD), vascular(VD) and frontotemporal ... ...

    Abstract Objective: To describe the 10-year preclinical cognitive trajectories of older, non-demented individuals towards the onset of the four most prevalent types of dementia, i.e., Alzheimer's disease(AD), Lewy body(LBD), vascular(VD) and frontotemporal dementia(FTD).
    Methods: Our analysis focused on data from older (≥ 60years) NACC (National Alzheimer's Coordinating Center) participants. Four distinct presymptomatic dementia groups (AD-LBD-VD-FTD) and a comparison group of cognitively unimpaired(CU) participants were formed. Comprehensive cognitive assessments involving verbal episodic memory, semantic verbal fluency, confrontation naming, mental processing speed - attention and executive function - cognitive flexibility were conducted at baseline and on an approximately yearly basis. Descriptive analyses (adjusted general linear models) were performed to determine and compare the yearly cognitive scores of each group throughout the follow-up. Exploratory analyses were conducted to estimate the rates of cognitive decline.
    Results: There were 3343 participants who developed AD, 247 LBD, 108 FTD, 155 VD and 3398 composed the CU group. Participants with AD performed worse on episodic memory than those with VD and LBD for about 3 to 4 years prior to dementia onset (the FTD group documented an intermediate course). Presymptomatic verbal fluency and confrontation naming trajectories differentiated quite well between the FTD group and the remaining dementia entities. Participants with incident LBD and VD performed worse than those with AD on executive functions and mental processing speed-attention since about 5 years prior to the onset of dementia, and worse than those with FTD more proximally to the diagnosis of the disorder.
    Conclusions: Heterogeneous cognitive trajectories characterize the presymptomatic courses of the most prevalent dementia entities.
    Mesh-Begriff(e) Humans ; Aged ; Male ; Female ; Longitudinal Studies ; Cognition/physiology ; Dementia/epidemiology ; Neuropsychological Tests ; Middle Aged ; Alzheimer Disease/psychology ; Aged, 80 and over ; Disease Progression ; Databases, Factual ; Frontotemporal Dementia/psychology ; Frontotemporal Dementia/physiopathology ; Lewy Body Disease/psychology ; Lewy Body Disease/physiopathology ; Dementia, Vascular/psychology ; Dementia, Vascular/physiopathology ; Memory, Episodic ; Cognitive Dysfunction/diagnosis ; Executive Function/physiology
    Sprache Englisch
    Erscheinungsdatum 2024-05-23
    Erscheinungsland Germany
    Dokumenttyp Journal Article
    ZDB-ID 2104785-6
    ISSN 1720-8319 ; 1594-0667
    ISSN (online) 1720-8319
    ISSN 1594-0667
    DOI 10.1007/s40520-024-02769-9
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Volltext online

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  7. Artikel: Illiteracy, Neuropsychological Assessment, and Cognitive Rehabilitation: A Narrative Review.

    Petri, Maria / Messinis, Lambros / Patrikelis, Panayiotis / Nousia, Anastasia / Nasios, Grigorios

    Advances in experimental medicine and biology

    2023  Band 1425, Seite(n) 477–484

    Abstract: Object: Νeuropsychological assessment is particularly important for the accurate discrimination of cognitive abilities and weaknesses of patients in order to determine the appropriate therapeutic intervention. However, the reliability and validity of ... ...

    Abstract Object: Νeuropsychological assessment is particularly important for the accurate discrimination of cognitive abilities and weaknesses of patients in order to determine the appropriate therapeutic intervention. However, the reliability and validity of neuropsychological assessment appears to be influenced by a wide range of factors, including literacy and educational level.
    Aim: This systematic review evaluates neuropsychological tests appropriate for the valid assessment of illiterate individuals and the effectiveness of cognitive rehabilitation programs for illiterate and/or low-educated individuals according to the results of English language studies that have been published in the PubMed/Medline electronic database until August 2022 (no initiation date).
    Results: 49 studies were included for neuropsychological assessment and 4 studies for cognitive rehabilitation. In terms of investigating the validity and reliability of neuropsychological tests for the assessment of healthy illiterate individuals, most studies concluded that for the majority of neuropsychological tests there is a significant difference in performance between healthy illiterate and literate individuals. However, there was consensus among studies that the performance of illiterate subjects was equivalent to the performance of literate subjects on tasks depicting colored and real objects. Regarding cognitive rehabilitation programs, all four studies concluded that they are effective in improving the cognitive functions of illiterate and/or low-literate patients with mild cognitive impairment and/or mild dementia.
    Conclusions: For the assessment of illiterate individuals, it is imperative that neuropsychological tests with high ecological validity (i.e., tests related to activities of daily living) be administered so as not to underestimate their cognitive functioning. At the same time, cognitive enhancement/stimulation programs seem to be effective in this population group; however, this area needs further investigation.
    Mesh-Begriff(e) Humans ; Literacy ; Activities of Daily Living ; Reproducibility of Results ; Cognitive Training ; Neuropsychological Tests ; Cognitive Dysfunction/diagnosis
    Sprache Englisch
    Erscheinungsdatum 2023-08-23
    Erscheinungsland United States
    Dokumenttyp Systematic Review ; Journal Article
    ZDB-ID 410187-X
    ISSN 0065-2598
    ISSN 0065-2598
    DOI 10.1007/978-3-031-31986-0_46
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel: Cognitive Rehabilitation for Patients with Schizophrenia: A Narrative Review of Moderating Factors, Strategies, and Outcomes.

    Skokou, Maria / Messinis, Lambros / Nasios, Grigorios / Gourzis, Philippos / Dardiotis, Euthymios

    Advances in experimental medicine and biology

    2023  Band 1423, Seite(n) 193–199

    Abstract: Objective: Antipsychotic drugs constitute the basis of schizophrenia therapy; however, available pharmaceutical agents lack efficacy for treating the cognitive deficits caused by the illness. The aim of the present work is to present current data ... ...

    Abstract Objective: Antipsychotic drugs constitute the basis of schizophrenia therapy; however, available pharmaceutical agents lack efficacy for treating the cognitive deficits caused by the illness. The aim of the present work is to present current data regarding cognitive rehabilitation of schizophrenia, providing information and guidance to health professionals.
    Method: A literature search was conducted in the PubMed and Google Scholar Databases from inception up to 1/9/2022. Relevant articles were explored for factors affecting cognitive function, including genetics, psychopathology, time in the course of the illness, and drug therapy. Characteristics and outcome of cognitive rehabilitation programs are briefly presented.
    Results: A total of 562 relevant articles were retrieved, 39 of which were selected for the review. Factors contributing to a favorable outcome are young age, early phase of disease, symptomatic control of hostility and conceptual disorganization, lack of negative symptoms, management of drug side effects, and cognitive and cortical reserve. Some evidence for a procognitive effect seems to exist for atypical antipsychotics, clozapine, aripiprazole, memantine, modafinil, d-serine, and cycloserine. The Val/Val polymorphism of the COMT gene seems to be associated with worse outcome. Specific remediation strategies include programs such as Cognitive Enhancement Therapy (CET), Cognitive Adaptation Training (CAT), and RehaCom Cognitive Therapy Software, among others, all employing a range of techniques, from paper-and-pencil to computer-assisted, bottom-up, or top-down approaches, and varying neurocognitive targets.
    Conclusion: Cognitive symptoms, closely related to functional impairment, still remain a therapeutic challenge. Cognitive rehabilitation strategies are as yet the only treatment modality offering cognitive improvement to patients who struggle to recover.
    Mesh-Begriff(e) Humans ; Schizophrenia/drug therapy ; Schizophrenia/genetics ; Schizophrenia/diagnosis ; Cognitive Training ; Antipsychotic Agents/adverse effects ; Cognition ; Modafinil/pharmacology ; Modafinil/therapeutic use
    Chemische Substanzen Antipsychotic Agents ; Modafinil (R3UK8X3U3D)
    Sprache Englisch
    Erscheinungsdatum 2023-08-09
    Erscheinungsland United States
    Dokumenttyp Review ; Journal Article
    ZDB-ID 410187-X
    ISSN 0065-2598
    ISSN 0065-2598
    DOI 10.1007/978-3-031-31978-5_17
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel ; Online: Communication, Feeding and Swallowing Disorders in Neurological Diseases.

    Nasios, Grigorios / Messinis, Lambros / Dardiotis, Efthimios / Kassubek, Jan

    Behavioural neurology

    2022  Band 2022, Seite(n) 9851424

    Mesh-Begriff(e) Communication ; Deglutition Disorders ; Humans ; Nervous System Diseases/complications
    Sprache Englisch
    Erscheinungsdatum 2022-04-21
    Erscheinungsland Netherlands
    Dokumenttyp Editorial
    ZDB-ID 1001896-7
    ISSN 1875-8584 ; 0953-4180
    ISSN (online) 1875-8584
    ISSN 0953-4180
    DOI 10.1155/2022/9851424
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  10. Artikel: Pathophysiology and Symptomatology of Drooling in Parkinson's Disease.

    Polychronis, Sotirios / Nasios, Grigorios / Dardiotis, Efthimios / Messinis, Lambros / Pagano, Gennaro

    Healthcare (Basel, Switzerland)

    2022  Band 10, Heft 3

    Abstract: Drooling can present in patients with Parkinson's disease (PD), and it is manifested as an excessive pooling of saliva inside the oral cavity. Currently, the exact pathophysiological mechanism of drooling in PD is not yet fully explicated. Thus, it ... ...

    Abstract Drooling can present in patients with Parkinson's disease (PD), and it is manifested as an excessive pooling of saliva inside the oral cavity. Currently, the exact pathophysiological mechanism of drooling in PD is not yet fully explicated. Thus, it becomes crucial to understand if some clinical characteristics may emphasize drooling or if they are just concomitant. In PD, excessive drooling has been associated with a higher burden of non-motor symptoms, such as cognitive impairment, sleep problems, autonomic dysfunction, constipation and orthostatic hypotension, and of worse severity of motor fluctuations and bradykinesia. PD patients with excessive drooling also showed a reduction of striatal DAT availability at DaTSCAN imaging. Excessive drooling in patients with Parkinson's cannot be attributed to a single factor but to a mixture of factors, including but not limited to impaired nigrostriatal pathways.
    Sprache Englisch
    Erscheinungsdatum 2022-03-11
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2721009-1
    ISSN 2227-9032
    ISSN 2227-9032
    DOI 10.3390/healthcare10030516
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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