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Artikel: Anafilaxia por sugammadex en paciente pediátrico.

Joyanes-Romo, Juana Bautista / Navarro-Abad, Ana Isabel / Urra-Ardanaz, José Miguel / González-Jiménez, Óscar / Palacios, Alberto / Meneses-Sotomayor, Jaime Vinicio / Pascual, Marta / Villanueva, Ma Gracia / Garrido, Davinia / Joyanes, Ana / Galindo-Bonilla, Pedro Ángel

Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)

2021  Band 68, Heft 2, Seite(n) 137–139

Abstract: Introduction: Sugammadex is a cyclodextrin that reverses neuromuscular blockade, especially of rocuronium. The occurrence of anaphylaxis produced by its use is of 1:1000 and 1:20000; it is observed mainly in subjects of Asian origin.: Case report: A ... ...

Titelübersetzung Anaphylaxis sugammadex-induced in a pediatric patient.
Abstract Introduction: Sugammadex is a cyclodextrin that reverses neuromuscular blockade, especially of rocuronium. The occurrence of anaphylaxis produced by its use is of 1:1000 and 1:20000; it is observed mainly in subjects of Asian origin.
Case report: A 9-year-old boy of Asian origin who, after the administration of sugammadex, immediately manifested an episode of anaphylaxis, which was reverted by using adrenaline and antihistamines. The serum tryptase at two hours was 27.7 μg/L; at 6 weeks, it was 3 μ/L. The sugammadex 100 mg/mL skin test was positive. The basophil activation test was positive with sugammadex 20 mg/mL.
Conclusion: The temporal relationship between the administration of the drug, the clinical manifestations, the elevation of tryptase, and the diagnostic tests performed, disclosed the episode of anaphylaxis associated with hypersensitivity to sugammadex.
Mesh-Begriff(e) Anaphylaxis/chemically induced ; Child ; Humans ; Male ; Neuromuscular Nondepolarizing Agents/adverse effects ; Rocuronium ; Skin Tests ; Sugammadex/adverse effects
Chemische Substanzen Neuromuscular Nondepolarizing Agents ; Sugammadex (361LPM2T56) ; Rocuronium (WRE554RFEZ)
Sprache Spanisch
Erscheinungsdatum 2021-09-15
Erscheinungsland Mexico
Dokumenttyp Case Reports ; Journal Article
ZDB-ID 639125-4
ISSN 0002-5151
ISSN 0002-5151
DOI 10.29262/ram.v658i2.876
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