Article ; Online: A COVID-19 patient with intense burning pain.
2020 Volume 26, Issue 5, Page(s) 800–801
Abstract: A woman in her forties with asthma and COPD was admitted to a general medical floor with respiratory symptoms, body aches, and anosmia. Reverse transcription polymerase chain reaction detected severe acute respiratory syndrome coronavirus-2. Admission ... ...
| Abstract | A woman in her forties with asthma and COPD was admitted to a general medical floor with respiratory symptoms, body aches, and anosmia. Reverse transcription polymerase chain reaction detected severe acute respiratory syndrome coronavirus-2. Admission labs, including biomarkers of the systemic immunological dysfunction seen in many cases of coronavirus disease 2019 (COVID-19), were within normal ranges. On the second day of admission, she developed neck and back pain that was constant, burning in quality, and exacerbated by light touch and heat. Wearing clothing caused pain and interfered with her sleep. The area was tender to light finger stroke. The patient was given acetaminophen, NSAIDs, and opioids with no relief of pain. However, gabapentin was effective. At follow-up 1 month later, her symptoms were improved and still relieved by gabapentin. Neuropathic pain was seen in over 2% of COVID-19 patients in one observational study. The pain seen in our case was bilateral, involved an area innervated by multiple levels of spinal nerves, and was limited to the back. While it is rare, a significant number of COVID-19 patients are afflicted by neuropathic pain, and our case illustrates that gabapentin may be effective. |
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| MeSH term(s) | Acetaminophen/therapeutic use ; Analgesics/therapeutic use ; Asthma-Chronic Obstructive Pulmonary Disease Overlap Syndrome/complications ; Asthma-Chronic Obstructive Pulmonary Disease Overlap Syndrome/drug therapy ; Asthma-Chronic Obstructive Pulmonary Disease Overlap Syndrome/pathology ; Asthma-Chronic Obstructive Pulmonary Disease Overlap Syndrome/virology ; Back Pain/complications ; Back Pain/drug therapy ; Back Pain/pathology ; Back Pain/virology ; Betacoronavirus/pathogenicity ; COVID-19 ; Coronavirus Infections/complications ; Coronavirus Infections/drug therapy ; Coronavirus Infections/pathology ; Coronavirus Infections/virology ; Female ; Gabapentin/therapeutic use ; Humans ; Middle Aged ; Neck Pain/complications ; Neck Pain/drug therapy ; Neck Pain/pathology ; Neck Pain/virology ; Olfaction Disorders/complications ; Olfaction Disorders/drug therapy ; Olfaction Disorders/pathology ; Olfaction Disorders/virology ; Pain/complications ; Pain/drug therapy ; Pain/pathology ; Pain/virology ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/drug therapy ; Pneumonia, Viral/pathology ; Pneumonia, Viral/virology ; SARS-CoV-2 ; Treatment Outcome |
| Chemical Substances | Analgesics ; Acetaminophen (362O9ITL9D) ; Gabapentin (6CW7F3G59X) |
| Keywords | covid19 |
| Language | English |
| Publishing date | 2020-08-10 |
| Publishing country | United States |
| Document type | Case Reports ; Journal Article |
| ZDB-ID | 1283265-0 |
| ISSN | 1538-2443 ; 1355-0284 |
| ISSN (online) | 1538-2443 |
| ISSN | 1355-0284 |
| DOI | 10.1007/s13365-020-00887-4 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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