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  1. Artikel ; Online: Pulmonary Artery Stump Thrombus in a Patient With Remote History of Rastelli Procedure.

    Li, Weijia / Guan, Xuan / Nguyen, James / Lee, Kelvin

    CASE (Philadelphia, Pa.)

    2024  Band 8, Heft 3Part A, Seite(n) 167–169

    Sprache Englisch
    Erscheinungsdatum 2024-03-08
    Erscheinungsland United States
    Dokumenttyp Case Reports
    ISSN 2468-6441
    ISSN (online) 2468-6441
    DOI 10.1016/j.case.2023.12.011
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  2. Artikel ; Online: Concentration Enrichment in a Dissolving Microdroplet: Accessing Sub-nanomolar Electroanalysis.

    Rana, Ashutosh / Nguyen, James H / Renault, Christophe / Dick, Jeffrey E

    Analytical chemistry

    2024  Band 96, Heft 14, Seite(n) 5384–5391

    Abstract: Droplet evaporation has previously been used as a concentration enrichment strategy; however, the measurement technique of choice requires quantification in rather large volumes. Electrochemistry has recently emerged as a method to robustly probe volumes ...

    Abstract Droplet evaporation has previously been used as a concentration enrichment strategy; however, the measurement technique of choice requires quantification in rather large volumes. Electrochemistry has recently emerged as a method to robustly probe volumes even down to the attoliter (10
    Sprache Englisch
    Erscheinungsdatum 2024-03-27
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 1508-8
    ISSN 1520-6882 ; 0003-2700
    ISSN (online) 1520-6882
    ISSN 0003-2700
    DOI 10.1021/acs.analchem.3c04971
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    Zs.A 4033: Hefte anzeigen Standort:
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  3. Artikel ; Online: Antidepressant Tapering Is Not Routine But Could Be.

    Phelps, James / Nguyen, James / Coskey, Olivia Pipitone

    Journal of the American Board of Family Medicine : JABFM

    2023  Band 36, Heft 1, Seite(n) 145–151

    Abstract: Introduction: When antidepressants are discontinued, severe withdrawal symptoms are possible. Some patients have few or no problems stopping, whereas others struggle. That struggle can be minimized or prevented with careful dose tapering. How often is ... ...

    Abstract Introduction: When antidepressants are discontinued, severe withdrawal symptoms are possible. Some patients have few or no problems stopping, whereas others struggle. That struggle can be minimized or prevented with careful dose tapering. How often is that done?
    Methods: Using 7 years of medical records, we determined the percentage of patients who received a prescription for the lowest available dose of their antidepressant before it was discontinued, as an indicator of a deliberate taper.
    Results: Over that period, 8.9% of patients had evidence of tapering. The percentage increased from 4.9% in 2014 to a plateau around 10% in the past 4 years.
    Discussion: While reports of severe withdrawal are increasingly recognized and must be addressed, our data suggest that many patients can discontinue their antidepressants without a taper through the lowest dose. However, it is difficult to identify which patients will struggle without a careful taper. A "one-size-fits-all" taper approach is recommended, balancing the need for withdrawal prevention with the need to avoid unnecessary complexity for the majority of patients. The first decrement is key for all patients: it must go well. Thereafter many patients may accelerate but all should receive a prescription for the lowest available dose of their antidepressant.
    Mesh-Begriff(e) Humans ; Antidepressive Agents/therapeutic use ; Substance Withdrawal Syndrome/etiology ; Substance Withdrawal Syndrome/prevention & control ; Substance Withdrawal Syndrome/drug therapy ; Recurrence
    Chemische Substanzen Antidepressive Agents
    Sprache Englisch
    Erscheinungsdatum 2023-01-18
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 2239939-2
    ISSN 1558-7118 ; 1557-2625
    ISSN (online) 1558-7118
    ISSN 1557-2625
    DOI 10.3122/jabfm.2022.220239R1
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  4. Artikel ; Online: Comment on: A qualitative analysis of Black men's attitudes toward obesity and bariatric surgery.

    James, Tayler J / Nguyen, James D / Martin, Matthew J

    Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery

    2023  Band 19, Heft 10, Seite(n) 1108–1109

    Mesh-Begriff(e) Male ; Humans ; Health Knowledge, Attitudes, Practice ; Obesity/surgery ; Bariatric Surgery
    Sprache Englisch
    Erscheinungsdatum 2023-06-28
    Erscheinungsland United States
    Dokumenttyp Editorial
    ZDB-ID 2274243-8
    ISSN 1878-7533 ; 1550-7289
    ISSN (online) 1878-7533
    ISSN 1550-7289
    DOI 10.1016/j.soard.2023.06.003
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    Zs.A 6572: Hefte anzeigen Standort:
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  5. Artikel ; Online: Bile Acids-A Peek Into Their History and Signaling.

    Nguyen, James T / Shaw, Ryan Philip Henry / Anakk, Sayeepriyadarshini

    Endocrinology

    2022  Band 163, Heft 11

    Abstract: Bile acids wear many hats, including those of an emulsifier to facilitate nutrient absorption, a cholesterol metabolite, and a signaling molecule in various tissues modulating itching to metabolism and cellular functions. Bile acids are synthesized in ... ...

    Abstract Bile acids wear many hats, including those of an emulsifier to facilitate nutrient absorption, a cholesterol metabolite, and a signaling molecule in various tissues modulating itching to metabolism and cellular functions. Bile acids are synthesized in the liver but exhibit wide-ranging effects indicating their ability to mediate organ-organ crosstalk. So, how does a steroid metabolite orchestrate such diverse functions? Despite the inherent chemical similarity, the side chain decorations alter the chemistry and biology of the different bile acid species and their preferences to bind downstream receptors distinctly. Identification of new modifications in bile acids is burgeoning, and some of it is associated with the microbiota within the intestine. Here, we provide a brief overview of the history and the various receptors that mediate bile acid signaling in addition to its crosstalk with the gut microbiota.
    Mesh-Begriff(e) Bile Acids and Salts/metabolism ; Cholesterol/metabolism ; Gastrointestinal Microbiome ; Intestines ; Liver/metabolism ; Signal Transduction
    Chemische Substanzen Bile Acids and Salts ; Cholesterol (97C5T2UQ7J)
    Sprache Englisch
    Erscheinungsdatum 2022-09-21
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 427856-2
    ISSN 1945-7170 ; 0013-7227
    ISSN (online) 1945-7170
    ISSN 0013-7227
    DOI 10.1210/endocr/bqac155
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel: Judgement aggregation in scientific collaborations: The case for waiving expertise.

    Marcoci, Alexandru / Nguyen, James

    Studies in history and philosophy of science

    2020  Band 84, Seite(n) 66–74

    Abstract: The fragmentation of academic disciplines forces individuals to specialise. In doing so, they become experts over their narrow area of research. However, ambitious scientific projects, such as the search for gravitational waves, require them to come ... ...

    Abstract The fragmentation of academic disciplines forces individuals to specialise. In doing so, they become experts over their narrow area of research. However, ambitious scientific projects, such as the search for gravitational waves, require them to come together and collaborate across disciplinary borders. How should scientists with expertise in different disciplines treat each others' expert claims? An intuitive answer is that the collaboration should defer to the opinions of experts. In this paper we show that under certain seemingly innocuous assumptions, this intuitive answer gives rise to an impossibility result when it comes to aggregating the beliefs of experts to deliver the beliefs of a collaboration as a whole. We then argue that when experts' beliefs come into conflict, they should waive their expert status.
    Mesh-Begriff(e) Humans ; Judgment
    Sprache Englisch
    Erscheinungsdatum 2020-09-08
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 202358-1
    ISSN 1879-2510 ; 0039-3681
    ISSN (online) 1879-2510
    ISSN 0039-3681
    DOI 10.1016/j.shpsa.2020.08.001
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    Verfügbar in ZB MED Bonn

    Z 91/732: Hefte anzeigen

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  7. Buch ; Online: Performance Analysis of Empirical Open-Circuit Voltage Modeling in Lithium Ion Batteries, Part-2

    Pillai, Prarthana / Nguyen, James / Balasingam, Balakumar

    Data Collection Procedure

    2023  

    Abstract: This paper is the second part of a series of papers about empirical approaches to open circuit voltage (OCV) modeling and its performance comparison in lithium-ion batteries. The first part of the series introduced various sources of uncertainties in the ...

    Abstract This paper is the second part of a series of papers about empirical approaches to open circuit voltage (OCV) modeling and its performance comparison in lithium-ion batteries. The first part of the series introduced various sources of uncertainties in the OCV models and established a theoretical relationship between uncertainties and the performance of a battery management system. In this paper, clearly defined approaches for low-rate OCV data collection are defined and described in detail. The data collection is designed with consideration to several parameters that affect the experimental time. Firstly, a more suitable method to fully charge the battery at different C-Rates is defined. Secondly, the OCV characterization following the full charge is described for various performance comparisons. Finally, optimal and efficient resistance estimation profiles are discussed. From the voltage, current and time data recorded using the procedure described in this paper, the OCV-SOC relationship is characterized and its uncertainties are modeled in the third part of this series of papers.
    Schlagwörter Electrical Engineering and Systems Science - Systems and Control
    Thema/Rubrik (Code) 330
    Erscheinungsdatum 2023-06-28
    Erscheinungsland us
    Dokumenttyp Buch ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  8. Buch ; Online: Performance Analysis of Empirical Open-Circuit Voltage Modeling in Lithium Ion Batteries, Part-1

    Pillai, Prarthana / Nguyen, James / Balasingam, Balakumar

    Performance Measures

    2023  

    Abstract: The open circuit voltage to the state of charge (OCVSOC) characteristic is crucial for battery management systems. Using the OCV-SOC curve, the SOC and the battery capacity can be estimated in real-time. Accurate SOC and capacity information are ... ...

    Abstract The open circuit voltage to the state of charge (OCVSOC) characteristic is crucial for battery management systems. Using the OCV-SOC curve, the SOC and the battery capacity can be estimated in real-time. Accurate SOC and capacity information are important to carry out the majority of battery management functionalities that ensure a safe, efficient, and reliable battery pack power system. Numerous approaches have been reported in the literature for improved SOC estimation and battery capacity estimation. These approaches focus on various estimation and filtering techniques to reduce the effect of measurement noise and uncertainties due to hysteresis and relaxation effects. Even though all the existing approaches to SOC estimation rely on the OCV-SOC characterization, little attention was paid to investigating the possibility of errors in the OCV-SOC characterization and the effect of uncertainty in the OCV-SOC curve on SOC and capacity estimates. In this paper, which is the first part of a series of three papers, the effect of OCV-SOC modeling error in the overall battery management system is discussed. The different sources of uncertainties in the OCV-SOC curve include cell-to-cell variation, temperature variation, aging drift, cycle rate effect, curve-fitting error, and measurement/estimation error. The proposed uncertainty models can be incorporated into battery management systems to improve their safety, performance, and reliability.
    Schlagwörter Electrical Engineering and Systems Science - Systems and Control
    Thema/Rubrik (Code) 690
    Erscheinungsdatum 2023-06-28
    Erscheinungsland us
    Dokumenttyp Buch ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  9. Buch ; Online: Performance Analysis of Empirical Open-Circuit Voltage Modeling in Lithium Ion Batteries, Part-3

    Pillai, Prarthana / Nguyen, James / Balasingam, Balakumar

    Experimental Results

    2023  

    Abstract: This paper is the third part of a series of papers about empirical approaches to open circuit voltage (OCV) modeling of lithium-ion batteries. The first part of the series proposed models to quantify various sources of uncertainties in the OCV models; ... ...

    Abstract This paper is the third part of a series of papers about empirical approaches to open circuit voltage (OCV) modeling of lithium-ion batteries. The first part of the series proposed models to quantify various sources of uncertainties in the OCV models; and, the second part of the series presented systematic data collection approaches to compute the uncertainties in the OCV-SOC models. This paper uses data collected from 28 OCV characterization experiments, performed according to the data collection plan presented, to compute and analyze the following three different OCV uncertainty metrics: cell-to-cell variations, cycle-rate error, and curve fitting error. From the computed metrics, it was observed that a lower C-Rate showed smaller errors in the OCV-SOC model and vice versa. The results reported in this paper establish a relationship between the C-Rate and the uncertainty of the OCV-SOC model. This research can be thus useful to battery researchers for quantifying the tradeoff between the time taken to complete the OCV characterization test and the corresponding uncertainty in the OCV-SOC modeling. Further, quantified uncertainty model parameters can be used to accurately characterize the uncertainty in various battery management functionalities, such as state of charge and state of health estimation.
    Schlagwörter Electrical Engineering and Systems Science - Systems and Control
    Erscheinungsdatum 2023-06-28
    Erscheinungsland us
    Dokumenttyp Buch ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  10. Artikel: emagnification: A tool for estimating effect-size magnification and performing design calculations in epidemiological studies.

    Miller, David J / Nguyen, James T / Bottai, Matteo

    The Stata journal

    2021  Band 20, Heft 3, Seite(n) 548–564

    Abstract: Artificial effect-size magnification (ESM) may occur in underpowered studies, where effects are reported only because they or their ... ...

    Abstract Artificial effect-size magnification (ESM) may occur in underpowered studies, where effects are reported only because they or their associated
    Sprache Englisch
    Erscheinungsdatum 2021-07-12
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 2209308-4
    ISSN 1536-8734 ; 1536-867X
    ISSN (online) 1536-8734
    ISSN 1536-867X
    DOI 10.1177/1536867x20953567
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