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  1. Artikel ; Online: Fluorescent nano-sized aggregates of halogen bonded complexes formed using perfluoropropyl iodides: a systematic comparison between two isomeric halogen bond acceptors, aniline and 4-methyl pyridine.

    Fan, Haiyan / Nurtay, Lazzat / Daniyeva, Nurgul / Benassi, Enrico

    Physical chemistry chemical physics : PCCP

    2023  Band 25, Heft 25, Seite(n) 16938–16951

    Abstract: The halogen bonds (XB) formed by the two isomers 4-methyl pyridine (MePy) and aniline (ANL) with heptafluoro-1-propyl iodide (n- ... ...

    Abstract The halogen bonds (XB) formed by the two isomers 4-methyl pyridine (MePy) and aniline (ANL) with heptafluoro-1-propyl iodide (n-C
    Sprache Englisch
    Erscheinungsdatum 2023-06-28
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 1476244-4
    ISSN 1463-9084 ; 1463-9076
    ISSN (online) 1463-9084
    ISSN 1463-9076
    DOI 10.1039/d3cp01225e
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Mechanism of the antimicrobial activity induced by phosphatase inhibitor sodium ortho-vanadate.

    Fan, Haiyan / Dukenbayev, Kanat / Nurtay, Lazzat / Nazir, Faisal / Daniyeva, Nurgul / Pham, Tri T / Benassi, Enrico

    Journal of inorganic biochemistry

    2024  Band 258, Seite(n) 112619

    Abstract: The present study describes a novel antimicrobial mechanism based on Sodium Orthovanadate (SOV), an alkaline phosphatase inhibitor. Scanning electron microscopy (SEM), transmission electron microscopy (TEM) and atomic force microscopy (AFM) were employed ...

    Abstract The present study describes a novel antimicrobial mechanism based on Sodium Orthovanadate (SOV), an alkaline phosphatase inhibitor. Scanning electron microscopy (SEM), transmission electron microscopy (TEM) and atomic force microscopy (AFM) were employed to examine the surface morphologies of the test organism, Escherichia coli (E. coli), during various antibacterial phases. Our results indicated that SOV kills bacteria by attacking cell wall growth and development, leaving E. coli's outer membrane intact. Our antimicrobial test indicated that the MIC of SOV for both E. coli and Lactococcus lactis (L. lactis) is 40 μM. A combination of quantum mechanical calculations and vibrational spectroscopy revealed that divanadate from SOV strongly coordinates with Ca
    Sprache Englisch
    Erscheinungsdatum 2024-05-27
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 162843-4
    ISSN 1873-3344 ; 0162-0134
    ISSN (online) 1873-3344
    ISSN 0162-0134
    DOI 10.1016/j.jinorgbio.2024.112619
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Intermolecular interactions in the crystalline structure of some polyhalogenated Di- And triamino Pyridines: Spectroscopical perspectives.

    Benassi, Enrico / Vaganova, Tamara / Malykhin, Evgenij / Gatilov, Yurij / Nurtay, Lazzat / Fan, Haiyan

    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy

    2022  Band 281, Seite(n) 121632

    Abstract: Supramolecular synthon is identified as a unit and provides important structural and energetic information in the study of organic crystals. However, the direct estimation of the supramolecular interaction remains challenging. In the present work six ... ...

    Abstract Supramolecular synthon is identified as a unit and provides important structural and energetic information in the study of organic crystals. However, the direct estimation of the supramolecular interaction remains challenging. In the present work six polyhalogenated di- or triamino pyridines were synthesised, their crystalline structure was characterised, and corresponding supramolecular synthons were studied using a combination of quantum mechanical calculations and FT-IR and Raman spectroscopy. Some distinctive features were identified especially for three vibrational normal modes (RNMs) related to the pyridine ring (viz. RNM
    Mesh-Begriff(e) Hydrogen Bonding ; Models, Molecular ; Quantum Theory ; Spectroscopy, Fourier Transform Infrared ; Spectrum Analysis, Raman ; Vibration
    Sprache Englisch
    Erscheinungsdatum 2022-07-16
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 210413-1
    ISSN 1873-3557 ; 0370-8322 ; 0584-8539 ; 1386-1425
    ISSN (online) 1873-3557
    ISSN 0370-8322 ; 0584-8539 ; 1386-1425
    DOI 10.1016/j.saa.2022.121632
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel ; Online: Novel carbon nanozymes with enhanced phosphatase-like catalytic activity for antimicrobial applications.

    Nurtay, Lazzat / Benassi, Enrico / Nazir, Faisal / Dastan, Dana / Utupova, Assem / Dautov, Adilet / Dukenbayev, Kanat / Xie, Yingqiu / Pham, Tri T / Fan, Haiyan

    Discover nano

    2023  Band 18, Heft 1, Seite(n) 76

    Abstract: In this work, Sulfur and Nitrogen co-doped carbon nanoparticles (SN-CNPs) were synthesized by hydrothermal method using dried beet powder as the carbon source. TEM and AFM images indicated that these SN-CNPs form a round-shape ball with an approximate ... ...

    Abstract In this work, Sulfur and Nitrogen co-doped carbon nanoparticles (SN-CNPs) were synthesized by hydrothermal method using dried beet powder as the carbon source. TEM and AFM images indicated that these SN-CNPs form a round-shape ball with an approximate diameter of 50 nm. The presence of Sulfur and Nitrogen in these carbon-based nanoparticles was confirmed by FTIR and XPS analyses. These SN-CNPs were found to have strong phosphatase-like enzymatic activity. The enzymatic behavior of SN-CNPs follows the Michaelis-Menten mechanism with greater v
    Sprache Englisch
    Erscheinungsdatum 2023-05-23
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ISSN 2731-9229
    ISSN (online) 2731-9229
    DOI 10.1186/s11671-023-03856-y
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: Nano-evolution and protein-based enzymatic evolution predicts novel types of natural product nanozymes of traditional Chinese medicine: cases of herbzymes of Taishan-Huangjing (

    Nazarbek, Guldan / Kutzhanova, Aidana / Nurtay, Lazzat / Mu, Chenglin / Kazybay, Bexultan / Li, Xugang / Ma, Cuiping / Amin, Amr / Xie, Yingqiu

    Nanoscale advances

    2021  Band 3, Heft 23, Seite(n) 6728–6738

    Abstract: Nanozymes and natural product-derived herbzymes have been identified in different types of enzymes simulating the natural protein-based enzyme function. How to explore and predict enzyme types of novel nanozymes when synthesized remains elusive. An ... ...

    Abstract Nanozymes and natural product-derived herbzymes have been identified in different types of enzymes simulating the natural protein-based enzyme function. How to explore and predict enzyme types of novel nanozymes when synthesized remains elusive. An informed analysis might be useful for the prediction. Here, we applied a protein-evolution analysis method to predict novel types of enzymes with experimental validation. First, reported nanozymes were analyzed by chemical classification and nano-evolution. We found that nanozymes are predominantly classified as protein-based EC1 oxidoreductase. In comparison, we analyzed the evolution of protein-based natural enzymes by a phylogenetic tree and the most conserved enzymes were found to be peroxidase and lyase. Therefore, the natural products of
    Sprache Englisch
    Erscheinungsdatum 2021-08-12
    Erscheinungsland England
    Dokumenttyp Journal Article
    ISSN 2516-0230
    ISSN (online) 2516-0230
    DOI 10.1039/d1na00475a
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel ; Online: Rhizoma polygonati

    Nurtay, Lazzat / Sun, Qinglei / Mu, Chenglin / Cao, Zhongshan / Wang, Qian / Liang, Zongsuo / Ma, Cuiping / Li, Xugang / Amin, Amr / Xie, Yingqiu

    Acupuncture and herbal medicine

    2021  Band 1, Heft 1, Seite(n) 31–38

    Abstract: Recently, traditional Chinese medicine-based treatment has succeeded in fighting coronavirus disease 2019 (COVID-19), ... ...

    Abstract Recently, traditional Chinese medicine-based treatment has succeeded in fighting coronavirus disease 2019 (COVID-19), and
    Sprache Englisch
    Erscheinungsdatum 2021-09-07
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Review
    ISSN 2765-8619
    ISSN (online) 2765-8619
    DOI 10.1097/HM9.0000000000000008
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel ; Online: Network pharmacology and experimental investigation of

    Xie, Yingqiu / Mu, Chengling / Kazybay, Bexultan / Sun, Qinglei / Kutzhanova, Aidana / Nazarbek, Guldan / Xu, Na / Nurtay, Lazzat / Wang, Qian / Amin, Amr / Li, Xugang

    Drug delivery

    2021  Band 28, Heft 1, Seite(n) 2187–2197

    Abstract: ... Rhizoma ... ...

    Abstract Rhizoma polygonati
    Mesh-Begriff(e) Cell Enlargement/drug effects ; Cell Line, Tumor ; Drugs, Chinese Herbal/pharmacology ; Humans ; Network Pharmacology/methods ; Plant Extracts/pharmacology ; Polygonatum ; Protein Interaction Maps ; Proto-Oncogene Proteins c-akt/drug effects ; TOR Serine-Threonine Kinases/drug effects
    Chemische Substanzen Drugs, Chinese Herbal ; Plant Extracts ; Proto-Oncogene Proteins c-akt (EC 2.7.11.1) ; TOR Serine-Threonine Kinases (EC 2.7.11.1)
    Sprache Englisch
    Erscheinungsdatum 2021-10-18
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 1213261-5
    ISSN 1521-0464 ; 1071-7544
    ISSN (online) 1521-0464
    ISSN 1071-7544
    DOI 10.1080/10717544.2021.1977422
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel ; Online: Generation of particle assemblies mimicking enzymatic activity by processing of herbal food: the case of rhizoma polygonati and other natural ingredients in traditional Chinese medicine.

    Benassi, Enrico / Fan, Haiyan / Sun, Qinglei / Dukenbayev, Kanat / Wang, Qian / Shaimoldina, Ainur / Tassanbiyeva, Aigerim / Nurtay, Lazzat / Nurkesh, Ayan / Kutzhanova, Aidana / Mu, Chenglin / Dautov, Adilet / Razbekova, Madina / Kabylda, Anar / Yang, Qing / Li, Ziye / Amin, Amr / Li, Xugang / Xie, Yingqiu

    Nanoscale advances

    2021  Band 3, Heft 8, Seite(n) 2222–2235

    Abstract: Processed herbs have been widely used in eastern and western medicine; however, the mechanism of their medicinal effects has not yet been revealed. It is commonly believed that a central role is played by chemically active molecules produced by the herbs' ...

    Abstract Processed herbs have been widely used in eastern and western medicine; however, the mechanism of their medicinal effects has not yet been revealed. It is commonly believed that a central role is played by chemically active molecules produced by the herbs' metabolism. In this work, processed rhizoma polygonati (RP) and other herbal foods are shown to exhibit intrinsic phosphatase-like (PL) activity bounded with the formation of nano-size flower-shaped assembly.
    Sprache Englisch
    Erscheinungsdatum 2021-01-13
    Erscheinungsland England
    Dokumenttyp Journal Article
    ISSN 2516-0230
    ISSN (online) 2516-0230
    DOI 10.1039/d0na00958j
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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