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Artikel ; Online: Survey of nonsusceptible nasopharyngeal Streptococcus pneumoniae isolates in children attending day-care centers in Brazil.

Franco, Caritas M / Andrade, Ana Lucia S / Andrade, João G / Almeida e Silva, Simonne / Oliveira, C Renato M / Pimenta, Fabiana C / Lamaro-Cardoso, Juliana / Brandão, Angela P / Almeida, Samanta C G / Calix, Juan J / Nahm, Moon H / de Cunto Brandileone, Maria-Cristina

The Pediatric infectious disease journal

2010  Band 29, Heft 1, Seite(n) 77–79

Abstract: A survey of nasopharyngeal carriage of penicillin nonsusceptible pneumococcal (PNSp) isolates was conducted among 1192 children attending 62 day care centers in Brazil, where pneumococcal vaccination has not been routinely introduced. Nasopharyngeal ... ...

Abstract A survey of nasopharyngeal carriage of penicillin nonsusceptible pneumococcal (PNSp) isolates was conducted among 1192 children attending 62 day care centers in Brazil, where pneumococcal vaccination has not been routinely introduced. Nasopharyngeal pneumococcal carriage was detected in 686 (57.6%) infants, and 178 (25.9%) of them carried PNSp isolates. Being less than 24 months of age, hospitalization in the previous 3 months, and recurrent acute otitis media were independently associated with PNSp. Serotypes 14, 23F, 19A, 6A, 6B and 19F were the most common serotype isolated accounting for 80% of the PNSp. A high proportion (35/332) of non-(sero)typeable isolates was detected, 62.9% of them PNSp. Serotypes coverage projected for the pneumococcal conjugate vaccine (PCV) 13-valent vaccine (72%) was significantly higher compared with PCV7 (58.4%) and PCV 10-valent vaccine (59.3%).
Mesh-Begriff(e) Bacterial Typing Techniques ; Brazil/epidemiology ; Carrier State/epidemiology ; Carrier State/microbiology ; Child Day Care Centers ; Child, Preschool ; Cross-Sectional Studies ; Female ; Hospitalization/statistics & numerical data ; Humans ; Infant ; Male ; Nasopharynx/microbiology ; Otitis Media/epidemiology ; Penicillin Resistance ; Pneumococcal Infections/epidemiology ; Pneumococcal Infections/microbiology ; Prevalence ; Recurrence ; Serotyping ; Streptococcus pneumoniae/classification ; Streptococcus pneumoniae/drug effects ; Streptococcus pneumoniae/isolation & purification
Sprache Englisch
Erscheinungsdatum 2010-01-02
Erscheinungsland United States
Dokumenttyp Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID 392481-6
ISSN 1532-0987 ; 0891-3668
ISSN (online) 1532-0987
ISSN 0891-3668
DOI 10.1097/INF.0b013e3181af7e90
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