LIVIVO - Das Suchportal für Lebenswissenschaften

switch to English language
Erweiterte Suche

Suchergebnis

Treffer 1 - 10 von insgesamt 48

Suchoptionen

  1. Buch: Techniques in aquatic toxicology / [1]

    Ostrander, Gary K.

    (Environmental chemistry and toxicology aquatic sciences)

    1996  

    Verfasserangabe edited by Gary K. Ostrander
    Serientitel Environmental chemistry and toxicology aquatic sciences
    Techniques in aquatic toxicology
    Überordnung Techniques in aquatic toxicology
    Schlagwörter Wasseranalyse
    Schlagwörter Wasseruntersuchung ; Wasser
    Sprache Englisch
    Umfang 686 S. : Ill., graph. Darst.
    Verlag CRC
    Erscheinungsort Boca Raton u.a.
    Erscheinungsland Vereinigte Staaten
    Dokumenttyp Buch
    HBZ-ID HT007436283
    ISBN 1-566-70149-X ; 978-1-566-70149-5
    Datenquelle Katalog ZB MED Ernährung, Umwelt, Agrar

    Zusatzmaterialien

    Kategorien

  2. Buch ; Überordnung: Techniques in aquatic toxicology

    Ostrander, Gary K.

    1996  

    Verfasserangabe edited by Gary K. Ostrander
    Schlagwörter Water/Pollution/Toxicology/Measurement ; Water quality bioassay/Technique
    Sprache Englisch
    Erscheinungsverlauf 1996-9999
    Verlag CRC
    Erscheinungsort Boca Raton u.a.
    Erscheinungsland Vereinigte Staaten
    Dokumenttyp Buch ; Überordnung (Einzelbände anzeigen)
    Anmerkung Verlagsangabe wechselt
    HBZ-ID HT017443534
    Datenquelle Katalog ZB MED Ernährung, Umwelt, Agrar

    Zusatzmaterialien

    Kategorien

  3. Artikel ; Online: Castanospermine reduces Zika virus infection-associated seizure by inhibiting both the viral load and inflammation in mouse models.

    Tharappel, Anil M / Cheng, Yichen / Holmes, Eric H / Ostrander, Gary K / Tang, Hengli

    Antiviral research

    2020  Band 183, Seite(n) 104935

    Abstract: Zika virus (ZIKV) outbreaks have been reported worldwide, including a recent occurrence in Brazil where it spread rapidly, and an association with increased cases of microcephaly was observed in addition to neurological issues such as GBS that were ... ...

    Abstract Zika virus (ZIKV) outbreaks have been reported worldwide, including a recent occurrence in Brazil where it spread rapidly, and an association with increased cases of microcephaly was observed in addition to neurological issues such as GBS that were reported during previous outbreaks. Following infection of neuronal tissues, ZIKV can cause inflammation, which may lead to neuronal abnormalities, including seizures and paralysis. Therefore, a drug containing both anti-viral and immunosuppressive properties would be of great importance in combating ZIKV related neurological abnormalities. Castanospermine (CST) is potentially a right candidate drug as it reduced viral load and brain inflammation with the resulting appearance of delayed neuronal disorders, including seizures and paralysis in an Ifnar1
    Mesh-Begriff(e) Animals ; Antiviral Agents/therapeutic use ; Cell Line, Tumor ; Chlorocebus aethiops ; Disease Models, Animal ; Female ; Glioblastoma ; Humans ; Immunosuppressive Agents/therapeutic use ; Indolizines/therapeutic use ; Inflammation/drug therapy ; Inflammation/virology ; Male ; Mice ; Seizures/drug therapy ; Seizures/immunology ; Seizures/virology ; Vero Cells ; Viral Load/drug effects ; Zika Virus/drug effects ; Zika Virus Infection/complications ; Zika Virus Infection/drug therapy
    Chemische Substanzen Antiviral Agents ; Immunosuppressive Agents ; Indolizines ; castanospermine (Q0I3184XM7)
    Schlagwörter covid19
    Sprache Englisch
    Erscheinungsdatum 2020-09-16
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 306628-9
    ISSN 1872-9096 ; 0166-3542
    ISSN (online) 1872-9096
    ISSN 0166-3542
    DOI 10.1016/j.antiviral.2020.104935
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  4. Artikel: Transmissible Tumors: Breaking the Cancer Paradigm.

    Ostrander, Elaine A / Davis, Brian W / Ostrander, Gary K

    Trends in genetics : TIG

    2015  Band 32, Heft 1, Seite(n) 1–15

    Abstract: Transmissible tumors are those that have transcended the bounds of their incipient hosts by evolving the ability to infect another individual through direct transfer of cancer cells, thus becoming parasitic cancer clones. Coitus, biting, and scratching ... ...

    Abstract Transmissible tumors are those that have transcended the bounds of their incipient hosts by evolving the ability to infect another individual through direct transfer of cancer cells, thus becoming parasitic cancer clones. Coitus, biting, and scratching are transfer mechanisms for the two primary species studied, the domestic dog (Canis lupus familiaris) and the Tasmanian devil (Sarcophilus harrisii). Canine transmissible venereal tumors (CTVT) are likely thousands of years old, and have successfully travelled from host to host around the world, while the Tasmanian devil facial tumor disease (DFTD) is much younger and geographically localized. The dog tumor is not necessarily lethal, while the devil tumor has driven the population to near extinction. Transmissible tumors are uniform in that they have complex immunologic profiles, which allow them to escape immune detection by their hosts, sometimes for long periods of time. In this review, we explore how transmissible tumors in CTVT, DFTD, and as well as the soft-shell clam and Syrian hamster, can advance studies of tumor biology.
    Mesh-Begriff(e) Animals ; Biological Evolution ; Dog Diseases/transmission ; Dogs ; Facial Neoplasms/veterinary ; Genetic Variation ; Marsupialia ; Mesocricetus ; Mya ; Neoplasms/genetics ; Neoplasms/immunology ; Neoplasms/veterinary ; Venereal Tumors, Veterinary
    Sprache Englisch
    Erscheinungsdatum 2015-12-11
    Erscheinungsland England
    Dokumenttyp Journal Article ; Research Support, N.I.H., Intramural ; Review
    ZDB-ID 619240-3
    ISSN 1362-4555 ; 0168-9525 ; 0168-9479
    ISSN (online) 1362-4555
    ISSN 0168-9525 ; 0168-9479
    DOI 10.1016/j.tig.2015.10.001
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  5. Artikel ; Online: Molecular toxicology of corals: a review.

    Rotchell, Jeanette M / Ostrander, Gary K

    Journal of toxicology and environmental health. Part B, Critical reviews

    2011  Band 14, Heft 8, Seite(n) 571–592

    Abstract: Coral reefs worldwide have become increasingly affected by a phenomenon known as "coral bleaching," the loss of the symbiotic algae from the host corals. The underlying causes and mechanism(s) of coral bleaching are not well known, although several have ... ...

    Abstract Coral reefs worldwide have become increasingly affected by a phenomenon known as "coral bleaching," the loss of the symbiotic algae from the host corals. The underlying causes and mechanism(s) of coral bleaching are not well known, although several have been hypothesized. While coral bleaching has been a primary focus in recent years, corals respond differentially to numerous environmental stresses. The impacts of heat, hydrocarbons, salinity, sewage effluents, biocides, heavy metals, and ultraviolet light have been investigated in both laboratory experiments and field surveys among multiple coral species. Herein what is known regarding the biological impacts of such stresses on corals at the molecular level of organization is summarized. The objective is to focus attention at the early stages of biological effects in order to encourage and facilitate research that provide ways to understand how changes at the molecular level might elucidate processes likely occurring at the population level. This, in turn, should accelerate studies that may elucidate the cellular and physiological changes contributing to coral decline, rather than just document the continued global loss of coral diversity and abundance.
    Mesh-Begriff(e) Animals ; Anthozoa/drug effects ; Anthozoa/physiology ; Ecotoxicology/methods ; Environmental Monitoring ; Environmental Pollutants/adverse effects ; Environmental Pollutants/metabolism ; Fishes/genetics ; Molecular Biology ; Pigmentation/drug effects ; Sea Anemones/genetics ; Sequence Analysis, Protein ; Signal Transduction ; Species Specificity ; Urochordata/genetics
    Chemische Substanzen Environmental Pollutants
    Sprache Englisch
    Erscheinungsdatum 2011
    Erscheinungsland England
    Dokumenttyp Journal Article ; Review
    ZDB-ID 1415246-0
    ISSN 1521-6950 ; 1093-7404
    ISSN (online) 1521-6950
    ISSN 1093-7404
    DOI 10.1080/10937404.2011.615112
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  6. Buch: Techniques in aquatic toxicology

    Ostrander, Gary K

    (A CRC Press book)

    2005  

    Titelvarianten Aquatic toxicology
    Verfasserangabe ed. by Gary K. Ostrander
    Serientitel A CRC Press book
    Sprache Englisch
    Umfang XVI, 766 S., zahlr. Ill., graph. Darst., 27cm
    Verlag Taylor & Francis
    Erscheinungsort Boca Raton u.a.
    Dokumenttyp Buch
    Anmerkung Includes bibliographical references and index
    ISBN 1566706645 ; 9781566706643
    Datenquelle Ehemaliges Sondersammelgebiet Küsten- und Hochseefischerei

    Zusatzmaterialien

    Kategorien

  7. Buch: Techniques in aquatic toxicology

    Ostrander, Gary K

    (A CRC Press book)

    2005  

    Titelvarianten Aquatic toxicology
    Verfasserangabe ed. by Gary K. Ostrander
    Serientitel A CRC Press book
    Sprache Englisch
    Umfang XVI, 766 S., zahlr. Ill., graph. Darst., 27cm
    Verlag Taylor & Francis
    Erscheinungsort Boca Raton u.a.
    Dokumenttyp Buch
    Anmerkung Includes bibliographical references and index
    ISBN 1566706645 ; 9781566706643
    Datenquelle Katalog der Technische Informationsbibliothek Hannover

    Zusatzmaterialien

    Kategorien

  8. Buch: The laboratory fish

    Ostrander, Gary K

    (The handbook of experimental animals)

    2000  

    Verfasserangabe ed. by Gary K. Ostrander
    Serientitel The handbook of experimental animals
    Sprache Englisch
    Umfang XVI, 678 S, Ill., graph. Darst
    Verlag Acad. Press
    Erscheinungsort San Diego u.a.
    Dokumenttyp Buch
    Anmerkung Literaturangaben
    ISBN 0125296509 ; 9780125296502
    Datenquelle Ehemaliges Sondersammelgebiet Küsten- und Hochseefischerei

    Zusatzmaterialien

    Kategorien

  9. Buch: The laboratory fish

    Ostrander, Gary K

    (The handbook of experimental animals)

    2000  

    Verfasserangabe ed. by Gary K. Ostrander
    Serientitel The handbook of experimental animals
    Sprache Englisch
    Umfang XVI, 678 S, Ill., graph. Darst
    Verlag Acad. Press
    Erscheinungsort San Diego u.a.
    Dokumenttyp Buch
    Anmerkung Literaturangaben
    ISBN 0125296509 ; 9780125296502
    Datenquelle Bibliothek der Tierärztlichen Hochschule Hannover

    Zusatzmaterialien

    Kategorien

  10. Artikel ; Online: Genetics of athletic performance.

    Ostrander, Elaine A / Huson, Heather J / Ostrander, Gary K

    Annual review of genomics and human genetics

    2009  Band 10, Seite(n) 407–429

    Abstract: Performance enhancing polymorphisms (PEPs) are examples of natural genetic variation that affect the outcome of athletic challenges. Elite athletes, and what separates them from the average competitor, have been the subjects of discussion and debate for ... ...

    Abstract Performance enhancing polymorphisms (PEPs) are examples of natural genetic variation that affect the outcome of athletic challenges. Elite athletes, and what separates them from the average competitor, have been the subjects of discussion and debate for decades. While training, diet, and mental fitness are all clearly important contributors to achieving athletic success, the fact that individuals reaching the pinnacle of their chosen sports often share both physical and physiological attributes suggests a role for genetics. That multiple members of a family often participate in highly competitive events, such as the Olympics, further supports this argument. In this review, we discuss what is known regarding the genes and gene families, including the mitochondrial genome, that are believed to play a role in human athletic performance. Where possible, we describe the physiological impact of the critical gene variants and consider predictions about other potentially important genes. Finally, we discuss the implications of these findings on the future for competitive athletics.
    Mesh-Begriff(e) Athletic Performance ; DNA, Mitochondrial/genetics ; Doping in Sports ; Genetic Variation ; Humans ; Muscle, Skeletal/anatomy & histology ; Muscle, Skeletal/metabolism ; Phenotype ; Sports/physiology
    Chemische Substanzen DNA, Mitochondrial
    Sprache Englisch
    Erscheinungsdatum 2009
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, N.I.H., Intramural ; Review
    ZDB-ID 2037670-4
    ISSN 1545-293X ; 1527-8204
    ISSN (online) 1545-293X
    ISSN 1527-8204
    DOI 10.1146/annurev-genom-082908-150058
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

Zum Seitenanfang